Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2024
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 176
- +12 vs. Q2 2024
- Shares held
- 67.7M
- +5.14M (+8.2%) vs. Q2 2024
- Total value
- $3.55B
- +$976.9M (+38.0%) vs. Q2 2024
- New holders
- 31
- 61 more added
- Sold out
- 19
- 54 more reduced
1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 7,216,911 | $378.1M | 0.28% | −95,480−1.3% | Reduced |
| BlackRock, Inc. | 6,889,258 | $360.9M | 0.01% | +6,889,258 | New |
| Baker Bros. Advisors LP | 6,398,366 | $335.2M | 3.47% | +10.0% | Added |
| Ra Capital Management, L.P. | 6,084,412 | $318.8M | 3.68% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 3,879,796 | $203.3M | 0.04% | −1,408,839−26.6% | Reduced |
| Perceptive Advisors LLC | 3,560,214 | $186.5M | 4.00% | +113,635+3.3% | Added |
| Vanguard Group Inc | 3,447,911 | $180.6M | 0.00% | +87,216+2.6% | Added |
| NEA Management Company, LLC | 2,909,956 | $152.5M | 8.31% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 2,416,952 | $126.6M | 5.08% | +45,648+1.9% | Added |
| State Street Corp | 1,993,166 | $104.4M | 0.00% | −10,716−0.5% | Reduced |
| Federated Hermes, Inc. | 1,663,900 | $87.2M | 0.19% | +3,116+0.2% | Added |
| Polar Capital Holdings Plc | 1,500,000 | $78.6M | 0.46% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 1,299,490 | $68.1M | 0.58% | +117,120+9.9% | Added |
| Geode Capital Management, LLC | 1,256,188 | $65.8M | 0.01% | +3,499+0.3% | Added |
| Rock Springs Capital Management LP | 1,228,093 | $64.3M | 2.09% | −52,400−4.1% | Reduced |
| Alkeon Capital Management LLC | 1,167,700 | $61.2M | 0.34% | +167,700+16.8% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 1,111,043 | $58.2M | 0.14% | +143,800+14.9% | Added |
| Checkpoint Capital L.P. | 663,381 | $34.8M | 17.24% | −258,719−28.1% | Reduced |
| Commodore Capital LP | 650,000 | $34.1M | 2.13% | −575,000−46.9% | Reduced |
| Loomis Sayles & Co L P | 636,628 | $33.4M | 0.04% | +636,628 | New |
| Hood River Capital Management LLC | 614,598 | $32.2M | 0.52% | +614,598 | New |
| Janus Henderson Group PLC | 598,122 | $31.3M | 0.02% | +4,480+0.8% | Added |
| Price T Rowe Associates Inc | 550,530 | $28.8M | 0.00% | +24,588+4.7% | Added |
| Opaleye Management Inc. | 500,000 | $26.2M | 4.37% | −15,000−2.9% | Reduced |
| Northern Trust Corp | 498,466 | $26.1M | 0.00% | −982−0.2% | Reduced |
| Morgan Stanley | 464,604 | $24.3M | 0.00% | −11,047−2.3% | Reduced |
| OrbiMed Advisors LLC | 435,900 | $22.8M | 0.42% | −268,942−38.2% | Reduced |
| Charles Schwab Investment Management Inc | 433,866 | $22.7M | 0.00% | +5,908+1.4% | Added |
| Marshall Wace, LLP | 406,615 | $21.3M | 0.03% | +299,806+280.7% | Added |
| Cormorant Asset Management, LP | 400,000 | $21.0M | 1.11% | −75,000−15.8% | Reduced |
| Candriam Luxembourg S.C.A. | 395,377 | $20.7M | 0.12% | +123,979+45.7% | Added |
| Voloridge Investment Management, LLC | 353,323 | $18.5M | 0.07% | −108,865−23.6% | Reduced |
| National Bank of Canada | 341,507 | $17.9M | 0.02% | −62,735−15.5% | Reduced |
| Pictet Asset Management Holding SA | 329,339 | $17.3M | 0.02% | −472,457−58.9% | Reduced |
| Sofinnova Investments, Inc. | 276,678 | $14.5M | 1.20% | +276,678 | New |
| Invesco Ltd. | 264,417 | $13.9M | 0.00% | −12,283−4.4% | Reduced |
| Silverarc Capital Management, LLC | 255,578 | $13.4M | 3.02% | +70,916+38.4% | Added |
| Franklin Resources Inc | 259,416 | $13.0M | 0.00% | +26,739+11.5% | Added |
| UBS Asset Management Americas Inc | 225,373 | $11.8M | 0.00% | −11,058−4.7% | Reduced |
| Samsara BioCapital, LLC | 172,647 | $9.04M | 1.74% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 148,926 | $7.80M | 0.00% | −42,945−22.4% | Reduced |
| Nuveen Asset Management, LLC | 147,875 | $7.75M | 0.00% | −1,244−0.8% | Reduced |
| Woodline Partners LP | 143,823 | $7.53M | 0.06% | +99,576+225.0% | Added |
| Great Lakes Advisors, LLC | 136,950 | $7.17M | 0.06% | +136,950 | New |
| Standard Life Aberdeen plc | 112,804 | $5.91M | 0.01% | 00.0% | Unchanged |
| Jane Street Group, LLC | 109,186 | $5.72M | 0.01% | −37,314−25.5% | Reduced |
| Barclays PLC | 106,397 | $5.57M | 0.00% | +52,766+98.4% | Added |
| Bank of America Corp | 106,250 | $5.57M | 0.00% | +14,207+15.4% | Added |
| Voya Investment Management LLC | 102,832 | $5.39M | 0.01% | +65,021+172.0% | Added |
| Citadel Advisors LLC | 102,778 | $5.38M | 0.01% | +102,778 | New |
| Lord, Abbett & Co. LLC | 102,646 | $5.38M | 0.02% | +55+0.1% | Added |
| Hennion & Walsh Asset Management, Inc. | 100,961 | $5.29M | 0.25% | +4,583+4.8% | Added |
| Swiss National Bank | 89,300 | $4.68M | 0.00% | +600+0.7% | Added |
| Clearbridge Investments, LLC | 87,424 | $4.58M | 0.00% | −684−0.8% | Reduced |
| JPMorgan Chase & Co | 81,592 | $4.27M | 0.00% | −58,554−41.8% | Reduced |
| Rhumbline Advisers | 80,714 | $4.23M | 0.00% | −2,349−2.8% | Reduced |
| Ghost Tree Capital, LLC | 78,842 | $4.13M | 1.41% | −38,546−32.8% | Reduced |
| UBS Group AG | 76,634 | $4.01M | 0.00% | +10,692+16.2% | Added |
| First Trust Advisors LP | 70,762 | $3.71M | 0.00% | −20,248−22.2% | Reduced |
| Canada Pension Plan Investment Board | 67,000 | $3.51M | 0.00% | −350,000−83.9% | Reduced |
| Norges Bank | 66,276 | $3.47M | 0.00% | +23,038+53.3% | Added |
| Nisa Investment Advisors, LLC | 66,240 | $3.47M | 0.02% | −308,107−82.3% | Reduced |
| Rafferty Asset Management, LLC | 64,576 | $3.38M | 0.01% | −7,986−11.0% | Reduced |
| Alliancebernstein L.P. | 59,570 | $3.12M | 0.00% | −1,500−2.5% | Reduced |
| JGP Global Gestao de Recursos Ltda. | 56,378 | $2.95M | 5.78% | +50,564+869.7% | Added |
| Algert Global LLC | 54,171 | $2.84M | 0.08% | −49,961−48.0% | Reduced |
| Legal & General Group Plc | 50,852 | $2.66M | 0.00% | +1,081+2.2% | Added |
| FMR LLC | 50,295 | $2.63M | 0.00% | +22,306+79.7% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $2.57M | 2.22% | 00.0% | Unchanged |
| Wedge Capital Management L L P | 48,844 | $2.56M | 0.04% | −14,353−22.7% | Reduced |
| Manufacturers Life Insurance Company, The | 48,703 | $2.55M | 0.00% | −588−1.2% | Reduced |
| California State Teachers Retirement System | 43,916 | $2.30M | 0.00% | −841−1.9% | Reduced |
| Ameriprise Financial Inc | 41,887 | $2.19M | 0.00% | +1,472+3.6% | Added |
| Harbor Capital Advisors, Inc. | 41,368 | $2.17M | 0.09% | +6,741+19.5% | Added |
| StemPoint Capital LP | 41,268 | $2.16M | 0.65% | +41,268 | New |
| Citigroup Inc | 41,197 | $2.16M | 0.00% | +21,205+106.1% | Added |
| HighVista Strategies LLC | 37,426 | $1.96M | 0.68% | +23,064+160.6% | Added |
| Millennium Management LLC | 36,977 | $1.94M | 0.00% | +36,977 | New |
| Deutsche Bank AG | 33,264 | $1.74M | 0.00% | +7,204+27.6% | Added |
| AQR Capital Management LLC | 32,809 | $1.72M | 0.00% | −71,021−68.4% | Reduced |
| Principal Financial Group Inc | 32,586 | $1.71M | 0.00% | +23,054+241.9% | Added |
| State of Wisconsin Investment Board | 32,453 | $1.70M | 0.00% | −6,974−17.7% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 32,502 | $1.70M | 0.00% | +2,111+6.9% | Added |
| MetLife Investment Management | 31,652 | $1.66M | 0.01% | 00.0% | Unchanged |
| TD Asset Management Inc | 31,800 | $1.63M | 0.00% | +800+2.6% | Added |
| Schonfeld Strategic Advisors LLC | 30,535 | $1.60M | 0.01% | +19,614+179.6% | Added |
| Wells Fargo & Company | 29,474 | $1.54M | 0.00% | −61−0.2% | Reduced |
| Corebridge Financial, Inc. | 29,274 | $1.53M | 0.01% | −180−0.6% | Reduced |
| SEI Investments Co | 29,021 | $1.52M | 0.00% | +21,651+293.8% | Added |
| Wellington Management Group LLP | 27,716 | $1.45M | 0.00% | −174,610−86.3% | Reduced |
| Penserra Capital Management LLC | 25,063 | $1.31M | 0.03% | +25,063 | New |
| Susquehanna International Group, LLP | 21,481 | $1.13M | 0.00% | −2,644−11.0% | Reduced |
| Assenagon Asset Management S.A. | 20,052 | $1.05M | 0.00% | −209,439−91.3% | Reduced |
| Fiduciary Trust Co | 20,000 | $1.05M | 0.01% | 00.0% | Unchanged |
| Stifel Financial Corp | 19,842 | $1.04M | 0.00% | −8,216−29.3% | Reduced |
| Handelsbanken Fonder AB | 19,321 | $1.01M | 0.00% | +3,400+21.4% | Added |
| Castleark Management LLC | 19,260 | $1.01M | 0.04% | +250+1.3% | Added |
| Crestline Management, LP | 18,998 | $995.3K | 0.06% | +18,998 | New |
| Victory Capital Management Inc | 18,186 | $952.8K | 0.00% | +11,137+158.0% | Added |
| Jefferies Financial Group Inc. | 18,000 | $943.0K | 0.02% | +18,000 | New |