Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2023
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 169
- +25 vs. Q3 2023
- Shares held
- 66.7M
- −1.44M (−2.1%) vs. Q3 2023
- Total value
- $3.07B
- +$1.50B (+96.3%) vs. Q3 2023
- New holders
- 45
- 41 more added
- Sold out
- 20
- 64 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 8,052,648 | $370.2M | 0.29% | −214,773−2.6% | Reduced |
| Baker Bros. Advisors LP | 6,398,365 | $294.1M | 3.35% | −303,984−4.5% | Reduced |
| BlackRock Inc. | 6,351,750 | $292.0M | 0.01% | +151,868+2.4% | Added |
| Ra Capital Management, L.P. | 5,330,412 | $245.0M | 3.83% | −345,655−6.1% | Reduced |
| Goldman Sachs Group Inc | 5,047,934 | $232.1M | 0.05% | −112,607−2.2% | Reduced |
| Vanguard Group Inc | 3,226,938 | $148.3M | 0.00% | +212,370+7.0% | Added |
| NEA Management Company, LLC | 2,909,956 | $133.8M | 8.92% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 2,371,304 | $109.0M | 5.83% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 2,310,955 | $106.2M | 0.26% | −30,380−1.3% | Reduced |
| State Street Corp | 2,206,018 | $101.4M | 0.00% | −159,838−6.8% | Reduced |
| Perceptive Advisors LLC | 2,154,110 | $99.0M | 2.21% | +1,773,282+465.6% | Added |
| Polar Capital Holdings Plc | 1,750,000 | $80.4M | 0.56% | −750,000−30.0% | Reduced |
| Commodore Capital LP | 1,550,000 | $71.3M | 6.23% | −525,000−25.3% | Reduced |
| Rock Springs Capital Management LP | 1,522,893 | $70.0M | 1.73% | −74,230−4.6% | Reduced |
| Pictet Asset Management Holding SA | 1,163,961 | $53.5M | 0.06% | +1,163,961 | New |
| Geode Capital Management, LLC | 1,119,129 | $51.5M | 0.01% | +74,072+7.1% | Added |
| Checkpoint Capital L.P. | 730,000 | $33.6M | 23.42% | +730,000 | New |
| Janus Henderson Group PLC | 621,892 | $28.6M | 0.02% | −443,853−41.6% | Reduced |
| Opaleye Management Inc. | 610,000 | $28.0M | 7.53% | −43,000−6.6% | Reduced |
| Driehaus Capital Management LLC | 598,905 | $27.5M | 0.33% | +324,381+118.2% | Added |
| Price T Rowe Associates Inc | 572,297 | $26.3M | 0.00% | +361,945+172.1% | Added |
| Cormorant Asset Management, LP | 550,000 | $25.3M | 1.21% | −300,000−35.3% | Reduced |
| OrbiMed Advisors LLC | 536,642 | $24.7M | 0.49% | −47,000−8.1% | Reduced |
| FMR LLC | 529,130 | $24.3M | 0.00% | −339,344−39.1% | Reduced |
| Northern Trust Corp | 501,094 | $23.0M | 0.00% | −2,928−0.6% | Reduced |
| VR Adviser, LLC | 495,983 | $22.8M | 1.56% | −594,017−54.5% | Reduced |
| Charles Schwab Investment Management Inc | 397,685 | $18.3M | 0.00% | +12,937+3.4% | Added |
| Voloridge Investment Management, LLC | 362,717 | $16.7M | 0.07% | +342,350+1,680.9% | Added |
| Assenagon Asset Management S.A. | 301,636 | $13.9M | 0.04% | −105,654−25.9% | Reduced |
| Lord, Abbett & Co. LLC | 283,518 | $13.0M | 0.05% | +283,518 | New |
| Artisan Partners Limited Partnership | 271,421 | $12.5M | 0.02% | +271,421 | New |
| Canada Pension Plan Investment Board | 267,000 | $12.3M | 0.02% | +267,000 | New |
| Barclays PLC | 251,415 | $11.6M | 0.01% | +10,154+4.2% | Added |
| National Bank of Canada | 239,000 | $10.8M | 0.02% | +108,000+82.4% | Added |
| Morgan Stanley | 231,656 | $10.6M | 0.00% | −204,752−46.9% | Reduced |
| UBS Asset Management Americas Inc | 209,938 | $9.65M | 0.00% | −127,326−37.8% | Reduced |
| Jane Street Group, LLC | 184,359 | $8.47M | 0.01% | +40,357+28.0% | Added |
| Victory Capital Management Inc | 182,297 | $8.38M | 0.01% | +162,247+809.2% | Added |
| Bank of New York Mellon Corp | 180,222 | $8.28M | 0.00% | +2,846+1.6% | Added |
| Silverarc Capital Management, LLC | 174,248 | $8.01M | 2.47% | −86,289−33.1% | Reduced |
| Samsara BioCapital, LLC | 172,647 | $7.94M | 1.23% | −172,646−50.0% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 151,843 | $6.98M | 0.02% | −25,157−14.2% | Reduced |
| Nuveen Asset Management, LLC | 143,669 | $6.60M | 0.00% | +2,084+1.5% | Added |
| Wellington Management Group LLP | 139,802 | $6.43M | 0.00% | +2,359+1.7% | Added |
| Invesco Ltd. | 135,731 | $6.24M | 0.00% | +107,357+378.4% | Added |
| D. E. Shaw & Co., Inc. | 128,492 | $5.91M | 0.01% | +128,492 | New |
| Rafferty Asset Management, LLC | 121,654 | $5.59M | 0.02% | −41,150−25.3% | Reduced |
| Citadel Advisors LLC | 113,915 | $5.24M | 0.01% | −141,518−55.4% | Reduced |
| Dimensional Fund Advisors LP | 96,948 | $4.46M | 0.00% | 00.0% | Unchanged |
| Clearbridge Investments, LLC | 91,158 | $4.19M | 0.00% | −91,667−50.1% | Reduced |
| Swiss National Bank | 89,700 | $4.12M | 0.00% | −10,200−10.2% | Reduced |
| Rice Hall James & Associates, LLC | 89,605 | $4.12M | 0.24% | −67,821−43.1% | Reduced |
| UBS Group AG | 85,955 | $3.95M | 0.00% | +59,304+222.5% | Added |
| Jefferies Financial Group Inc. | 82,061 | $3.77M | 0.06% | −41,599−33.6% | Reduced |
| Natixis | 80,500 | $3.70M | 0.03% | +80,500 | New |
| JPMorgan Chase & Co | 77,599 | $3.57M | 0.00% | +5,188+7.2% | Added |
| Wedge Capital Management L L P | 76,507 | $3.52M | 0.06% | −28,213−26.9% | Reduced |
| Woodline Partners LP | 74,850 | $3.44M | 0.04% | +74,850 | New |
| Rhumbline Advisers | 73,172 | $3.36M | 0.00% | −287−0.4% | Reduced |
| Exome Asset Management LLC | 72,203 | $3.32M | 3.28% | +72,203 | New |
| Bank of America Corp | 69,870 | $3.21M | 0.00% | −40,373−36.6% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 66,708 | $3.07M | 0.18% | +26,562+66.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 65,544 | $3.01M | 0.01% | −66,118−50.2% | Reduced |
| Voya Investment Management LLC | 64,991 | $2.99M | 0.00% | −19,268−22.9% | Reduced |
| BNP Paribas Arbitrage, SA | 63,085 | $2.90M | 0.01% | +7,842+14.2% | Added |
| Zimmer Partners, LP | 61,800 | $2.84M | 0.10% | −20,700−25.1% | Reduced |
| HRT Financial LP | 54,534 | $2.51M | 0.02% | +3,982+7.9% | Added |
| Alliancebernstein L.P. | 54,390 | $2.50M | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 54,300 | $2.50M | 0.00% | −14,844−21.5% | Reduced |
| California State Teachers Retirement System | 48,997 | $2.25M | 0.00% | −2,537−4.9% | Reduced |
| Legal & General Group Plc | 46,828 | $2.15M | 0.00% | +3,674+8.5% | Added |
| Credit Suisse AG | 42,012 | $1.93M | 0.00% | −1,306−3.0% | Reduced |
| Alps Advisors Inc | 40,215 | $1.85M | 0.01% | −1,736−4.1% | Reduced |
| ExodusPoint Capital Management, LP | 40,197 | $1.85M | 0.02% | −112,246−73.6% | Reduced |
| Nan Fung Group Holdings Ltd | 40,070 | $1.84M | 1.15% | 00.0% | Unchanged |
| Wells Fargo & Company | 39,759 | $1.83M | 0.00% | −13,950−26.0% | Reduced |
| Manufacturers Life Insurance Company, The | 39,238 | $1.80M | 0.00% | +19,075+94.6% | Added |
| TD Asset Management Inc | 37,800 | $1.74M | 0.00% | +37,800 | New |
| State of Wisconsin Investment Board | 37,414 | $1.72M | 0.00% | −1,223−3.2% | Reduced |
| Millennium Management LLC | 34,831 | $1.60M | 0.00% | −3,941−10.2% | Reduced |
| Comerica Bank | 34,051 | $1.57M | 0.01% | −11,620−25.4% | Reduced |
| New York State Common Retirement Fund | 32,874 | $1.51M | 0.00% | +12,233+59.3% | Added |
| Bellevue Group AG | 32,869 | $1.51M | 0.02% | −40,431−55.2% | Reduced |
| Susquehanna International Group, LLP | 32,232 | $1.48M | 0.00% | +1,776+5.8% | Added |
| Stifel Financial Corp | 30,625 | $1.41M | 0.00% | −15,365−33.4% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 29,444 | $1.35M | 0.00% | −889−2.9% | Reduced |
| Algert Global LLC | 28,803 | $1.32M | 0.05% | −4,610−13.8% | Reduced |
| MetLife Investment Management | 27,123 | $1.25M | 0.01% | 00.0% | Unchanged |
| Deutsche Bank AG | 27,048 | $1.24M | 0.00% | −404−1.5% | Reduced |
| Virtu Financial LLC | 26,501 | $1.22M | 0.10% | +26,501 | New |
| American International Group, Inc. | 25,537 | $1.17M | 0.00% | −103−0.4% | Reduced |
| Atom Investors LP | 24,931 | $1.15M | 0.20% | +5,545+28.6% | Added |
| Ameriprise Financial Inc | 20,980 | $964.5K | 0.00% | −1,000−4.5% | Reduced |
| Profund Advisors LLC | 20,491 | $942.0K | 0.04% | −7,327−26.3% | Reduced |
| Fiduciary Trust Co | 20,000 | $919.4K | 0.02% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 18,550 | $852.7K | 0.00% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 18,473 | $849.2K | 0.02% | +4,154+29.0% | Added |
| Prelude Capital Management, LLC | 17,406 | $800.2K | 0.07% | +1,000+6.1% | Added |
| Royal Bank of Canada | 16,132 | $743.0K | 0.00% | +4,089+34.0% | Added |
| Squarepoint Ops LLC | 15,350 | $705.6K | 0.00% | +15,350 | New |