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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.57B in total; Duquesne Family Office is the only superinvestor holding it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Rhythm Pharmaceuticals, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
6 filings
6 insiders, $28.8M in total
Insiders trading
6
Net value
−$28.8M
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Rhythm Pharmaceuticals, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Rhythm Pharmaceuticals, Inc.
NameTitleLast reported holdingLast filingFilings, past year
Meeker David PPresident and CEO239,258Sep 14, 20263
Smith Hunter CChief Financial Officer114,024Sep 1, 20267
Joshi ManherChief Medical Officer–Aug 18, 20261
Shulman JosephChief Technical Officer15,915Aug 17, 20266
Garfield AlastairChief Scientific Officer2,295Aug 17, 20264
Chien JenniferEVP, Head of North America0Aug 14, 20263
Mazabraud YannEVP, Head of International55,655Aug 14, 20266
McGirr David W JDirector11,712Jun 25, 20261
Good Jennifer LDirector11,712Jun 25, 20261
Jean ChristopheDirector11,712Jun 25, 20261
Arbuckle Stuart ADirector11,712Jun 25, 20261
Tetrault Lynn A.Director11,712Jun 25, 20262
German Christopher PaulCorporate Controller & CAO0May 19, 20265
Popovits Kimberly JDirector–Apr 3, 20261
Mathers Edward TDirector14,168IndirectMar 16, 20262
Cramer Pamela J.Chief Human Resources Officer29,376Feb 13, 20265
Bedrosian Camille LDirector7,000Jun 26, 20250
Roberts William T.Chief Accounting Officer7,872Mar 31, 20230
Manning Linda ShapiroChief Medical Officer–Feb 11, 20220

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Sep 14, 2026 (view filing)7:37 PM ETSep 14Same dayMeeker David PPresident and CEOSSale−50.0K$102.67−$5.13M−17.3%239.3K after5 lots10b5-1
Sep 1, 2026 (view filing)4:22 PM ETAug 311 daySmith Hunter CChief Financial OfficerSSale−62.8K$105.46−$6.62M−35.5%114.0K after3 lots10b5-1
Aug 17, 2026 (view filing)6:00 PM ETAug 134 daysShulman JosephChief Technical OfficerSSale−5.08K$119.75−$608.2K−24.2%15.9K after10b5-1
Aug 17, 2026 (view filing)5:57 PM ETAug 134 daysGarfield AlastairChief Scientific OfficerSSale−7.76K$117.57−$912.7K−77.2%2.29K after4 lots10b5-1
Aug 14, 2026 (view filing)7:04 PM ETAug 131 dayChien JenniferEVP, Head of North AmericaSSale−75.8K$117.38−$8.90M−100.0%0 after10b5-1
Aug 14, 2026 (view filing)7:01 PM ETAug 122 daysMazabraud YannEVP, Head of InternationalSSale−57.0K$116.15−$6.62M−50.6%55.7K after6 lots10b5-1
Jun 24, 2026 (view filing)Jun 222 daysTetrault Lynn A.DirectorSSale−37.0K$100.32−$3.71M−84.1%7.00K after10b5-1
May 19, 2026 (view filing)May 154 daysGerman Christopher PaulCorporate Controller & CAOSSale−4.64K$92.21−$428.1K−100.0%0 after
Mar 6, 2026 (view filing)Mar 42 daysGerman Christopher PaulCorporate Controller & CAOSSale−5.61K$89.56−$502.8K−97.2%160 after
Feb 19, 2026 (view filing)Feb 17-192 daysSmith Hunter CChief Financial OfficerSSale−7.95K$101.31−$805.8K−6.7%110.5K after9 lots10b5-1
Feb 12, 2026 (view filing)Feb 10-122 daysSmith Hunter CChief Financial OfficerSSale−7.07K$100.21−$708.6K−5.6%118.5K after10 lots10b5-1
Feb 6, 2026 (view filing)Feb 4-52 daysSmith Hunter CChief Financial OfficerSSale−6.63K$106.02−$702.7K−5.0%125.5K after4 lots10b5-1
Dec 15, 2025 (view filing)Dec 114 daysCramer Pamela J.Chief Human Resources OfficerSSale−3.35K$111.00−$371.9K−13.9%20.8K after10b5-1
Nov 24, 2025 (view filing)Nov 204 daysCramer Pamela J.Chief Human Resources OfficerSSale−3.35K$105.00−$351.8K−13.9%20.8K after10b5-1
Nov 12, 2025 (view filing)Nov 7-105 daysCramer Pamela J.Chief Human Resources OfficerSSale−22.9K$99.00−$2.26M−52.3%20.8K after2 lots10b5-1
Nov 3, 2025 (view filing)Oct 304 daysShulman JosephChief Technical OfficerSSale−9.75K$115.24−$1.12M−53.4%8.51K after10b5-1
Oct 30, 2025 (view filing)Oct 282 daysShulman JosephChief Technical OfficerSSale−2.81K$115.01−$323.8K−24.9%8.51K after10b5-1
Oct 20, 2025 (view filing)Oct 164 daysShulman JosephChief Technical OfficerSSale−14.4K$112.03−$1.62M−62.9%8.51K after3 lots10b5-1
Sep 4, 2025 (view filing)Sep 22 daysShulman JosephChief Technical OfficerSSale−16.8K$105.30−$1.77M−66.4%8.51K after10b5-1
Aug 25, 2025 (view filing)Aug 214 daysShulman JosephChief Technical OfficerSSale−4.19K$100.07−$419.1K−33.0%8.51K after10b5-1
Aug 14, 2025 (view filing)Aug 12-132 daysSmith Hunter CChief Financial OfficerSSale−28.1K$96.29−$2.70M−19.4%116.9K after2 lots10b5-1
Aug 14, 2025 (view filing)Aug 122 daysGerman Christopher PaulCorporate Controller & CAOSSale−1.50K$95.00−$142.5K−61.9%922 after10b5-1
Aug 13, 2025 (view filing)Aug 112 daysShulman JosephChief Technical OfficerSSale−3.98K$90.08−$358.9K−31.9%8.51K after10b5-1
Jul 29, 2025 (view filing)Jul 29Same dayCramer Pamela J.Chief Human Resources OfficerSSale−1.52K$85.93−$130.6K−6.8%20.8K after10b5-1
Jul 11, 2025 (view filing)Jul 92 daysSmith Hunter CChief Financial OfficerSSale−42.1K$80.48−$3.39M−26.5%116.9K after3 lots10b5-1
Jul 11, 2025 (view filing)Jul 92 daysShulman JosephChief Technical OfficerSSale−7.97K$77.78−$619.8K−48.4%8.51K after2 lots10b5-1
Jul 11, 2025 (view filing)Jul 92 daysGerman Christopher PaulCorporate Controller & CAOSSale−3.82K$80.75−$308.2K−80.5%922 after2 lots10b5-1
Jul 11, 2025 (view filing)Jul 92 daysCramer Pamela J.Chief Human Resources OfficerSSale−15.6K$77.13−$1.20M−44.8%19.2K after3 lots10b5-1
Jul 3, 2025 (view filing)Jul 21 dayGarfield AlastairChief Scientific OfficerSSale−1.32K$64.81−$85.5K−29.7%3.13K after2 lots10b5-1
Jun 12, 2025 (view filing)Jun 102 daysGerman Christopher PaulCorporate Controller & CAOSSale−2.07K$67.19−$139.0K−52.3%1.89K after10b5-1
Jun 10, 2025 (view filing)Jun 64 daysCramer Pamela J.Chief Human Resources OfficerSSale−7.03K$68.05−$478.5K−26.8%19.2K after10b5-1
Jun 5, 2025 (view filing)Jun 32 daysMcGirr David W JDirectorSSale−65.4K$65.22−$4.27M−95.6%3.00K after2 lots10b5-1
Jun 5, 2025 (view filing)Jun 32 daysMeeker David PPresident and CEOSSale−43.6K$65.04−$2.84M−17.8%201.8K after2 lots10b5-1
Jun 3, 2025 (view filing)May 304 daysSmith Hunter CChief Financial OfficerSSale−23.4K$61.41−$1.44M−17.6%109.9K after2 lots10b5-1
May 1, 2025 (view filing)Apr 292 daysCramer Pamela J.Chief Human Resources OfficerSSale−7.03K$65.09−$457.6K−26.8%19.2K after10b5-1
May 1, 2025 (view filing)Apr 292 daysMazabraud YannEVP, Head of InternationalSSale−6.75K$65.08−$439.0K−15.2%37.7K after10b5-1
Apr 10, 2025 (view filing)Apr 82 daysCramer Pamela J.Chief Human Resources OfficerSSale−20.8K$60.14−$1.25M−51.9%19.2K after4 lots10b5-1
Apr 10, 2025 (view filing)Apr 82 daysMazabraud YannEVP, Head of InternationalSSale−17.8K$60.98−$1.08M−44.0%22.6K after2 lots10b5-1
Mar 24, 2025 (view filing)Mar 213 daysGerman Christopher PaulCorporate Controller & CAOSSale−344$54.23−$18.7K−10.6%2.89K after
Mar 18, 2025 (view filing)Mar 144 daysMazabraud YannEVP, Head of InternationalSSale−75.0K$51.48−$3.86M−65.0%40.4K after2 lots10b5-1
Feb 19, 2025 (view filing)Feb 19Same daySmith Hunter CChief Financial OfficerSSale−2.21K$57.22−$126.7K−2.0%109.9K after10b5-1
Feb 19, 2025 (view filing)Feb 19Same dayShulman JosephChief Technical OfficerSSale−1.23K$57.22−$70.3K−12.6%8.51K after10b5-1
Feb 19, 2025 (view filing)Feb 19Same dayMeeker David PPresident and CEOSSale−9.90K$57.22−$566.2K−4.7%201.3K after10b5-1
Feb 19, 2025 (view filing)Feb 19Same dayChien JenniferEVP, Head of North AmericaSSale−2.04K$57.22−$116.4K−25.8%5.86K after10b5-1
Feb 19, 2025 (view filing)Feb 19Same dayGerman Christopher PaulCorporate Controller & CAOSSale−635$57.22−$36.3K−23.5%2.07K after
Feb 19, 2025 (view filing)Feb 19Same dayCramer Pamela J.Chief Human Resources OfficerSSale−982$57.22−$56.2K−4.9%19.2K after10b5-1
Feb 14, 2025 (view filing)Feb 122 daysSmith Hunter CChief Financial OfficerSSale−751$56.39−$42.3K−0.7%105.5K after2 lots10b5-1
Feb 14, 2025 (view filing)Feb 122 daysShulman JosephChief Technical OfficerSSale−469$56.40−$26.5K−7.7%5.61K after2 lots10b5-1
Feb 14, 2025 (view filing)Feb 12-132 daysChien JenniferEVP, Head of North AmericaSSale−3.02K$57.03−$172.2K−55.8%2.39K after4 lots10b5-1
Feb 11, 2025 (view filing)Feb 11Same dayShulman JosephChief Technical OfficerSSale−794$57.51−$45.7K−99.2%6.08 after2 lots10b5-1