Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 307 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
Q3 2026 data is still coming in: 120 institutions have reported holding RYTM so far. See Q3 2026
- Institutional holders
- 307
- +23 vs. Q1 2026
- Shares held
- 77.2M
- +4.58M (+6.3%) vs. Q1 2026
- Total value
- $8.55B
- +$2.21B (+34.8%) vs. Q1 2026
- New holders
- 64
- 106 more added
- Sold out
- 41
- 101 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 307 | $8.55B |
| Q1 2026 | 287 | $6.42B |
| Q4 2025 | 283 | $7.80B |
| Q3 2025 | 266 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 177 | $3.55B |
| Q2 2024 | 166 | $2.85B |
| Q1 2024 | 168 | $2.95B |
| Q4 2023 | 170 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,666,837 | $740.2M | 6.43% | 00.0% | Unchanged |
| BlackRock, Inc. | 6,156,902 | $683.6M | 0.01% | −80,249−1.3% | Reduced |
| Baker Bros. Advisors LP | 5,604,483 | $622.3M | 3.12% | 00.0% | Unchanged |
| Primecap Management Co | 3,168,853 | $351.8M | 0.21% | −248,656−7.3% | Reduced |
| Vanguard Portfolio Management LLC | 3,136,895 | $348.3M | 0.02% | +96,177+3.2% | Added |
| Vanguard Capital Management LLC | 3,005,977 | $333.8M | 0.01% | +38,152+1.3% | Added |
| JPMorgan Chase & Co | 2,652,746 | $292.2M | 0.02% | +1,099,102+70.7% | Added |
| Perceptive Advisors LLC | 2,586,295 | $287.2M | 4.46% | +212,500+9.0% | Added |
| State Street Corp | 2,573,529 | $285.7M | 0.01% | +301,678+13.3% | Added |
| Price T Rowe Associates Inc | 2,566,171 | $284.9M | 0.03% | +911,295+55.1% | Added |
| Westfield Capital Management Co LP | 2,208,595 | $245.2M | 0.80% | +279,472+14.5% | Added |
| Goldman Sachs Group Inc | 2,126,502 | $236.1M | 0.02% | +161,070+8.2% | Added |
| Federated Hermes, Inc. | 1,785,716 | $198.3M | 0.29% | +499,413+38.8% | Added |
| Polar Capital Holdings Plc | 1,663,632 | $184.7M | 0.52% | +48,046+3.0% | Added |
| Geode Capital Management, LLC | 1,533,698 | $170.3M | 0.01% | +117,429+8.3% | Added |
| Capital Research Global Investors | 1,532,303 | $170.1M | 0.02% | +416,843+37.4% | Added |
| Citadel Advisors LLC | 1,263,652 | $140.3M | 0.08% | −154,967−10.9% | Reduced |
| Checkpoint Capital L.P. | 1,186,000 | $131.7M | 33.79% | −41,200−3.4% | Reduced |
| Siren, L.L.C. | 1,136,275 | $126.2M | 2.56% | +410,764+56.6% | Added |
| Morgan Stanley | 1,112,240 | $123.5M | 0.01% | +408,262+58.0% | Added |
| FMR LLC | 1,025,840 | $113.9M | 0.00% | −663,831−39.3% | Reduced |
| Pictet Asset Management Holding SA | 957,785 | $106.3M | 0.10% | +290,739+43.6% | Added |
| Jupiter Topco LLC | 925,490 | $102.8M | 0.04% | +925,490 | New |
| Woodline Partners LP | 758,891 | $84.3M | 0.26% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 894,723 | $77.8M | 0.03% | −15,690−1.7% | Reduced |
| Clearbridge Investments, LLC | 696,473 | $77.3M | 0.06% | +87,036+14.3% | Added |
| Rock Springs Capital Management LP | 692,598 | $76.9M | 3.75% | +2,850+0.4% | Added |
| Norges Bank | 685,844 | $76.1M | 0.01% | +685,844 | New |
| Franklin Resources Inc | 577,033 | $64.1M | 0.01% | −49,812−7.9% | Reduced |
| Charles Schwab Investment Management Inc | 552,738 | $61.4M | 0.01% | +26,279+5.0% | Added |
| Integral Health Asset Management, LLC | 550,000 | $61.1M | 2.51% | −50,000−8.3% | Reduced |
| Invesco Ltd. | 543,271 | $60.3M | 0.00% | +178,965+49.1% | Added |
| Northern Trust Corp | 540,332 | $60.0M | 0.01% | +41,818+8.4% | Added |
| UBS Asset Management Americas Inc | 514,850 | $57.2M | 0.01% | −26,600−4.9% | Reduced |
| Wellington Management Group LLP | 488,747 | $54.3M | 0.01% | +214,990+78.5% | Added |
| Vanguard Fiduciary Trust Co | 445,723 | $49.5M | 0.01% | +23,812+5.6% | Added |
| Loomis Sayles & Co L P | 434,102 | $48.2M | 0.06% | −31,000−6.7% | Reduced |
| Candriam Luxembourg S.C.A. | 433,025 | $48.0M | 0.22% | −31,315−6.7% | Reduced |
| Squarepoint Ops LLC | 422,921 | $47.0M | 0.09% | +159,953+60.8% | Added |
| Point72 Asset Management, L.P. | 414,210 | $46.0M | 0.07% | −432,591−51.1% | Reduced |
| Sofinnova Investments, Inc. | 408,027 | $45.3M | 2.42% | −42,069−9.3% | Reduced |
| Ameriprise Financial Inc | 401,634 | $44.6M | 0.01% | +17,677+4.6% | Added |
| Adage Capital Partners GP, L.L.C. | 397,000 | $44.1M | 0.06% | −328,744−45.3% | Reduced |
| Bank of New York Mellon Corp | 394,044 | $43.8M | 0.01% | +100,746+34.3% | Added |
| Braidwell LP | 381,128 | $42.3M | 1.57% | +70,500+22.7% | Added |
| Artisan Partners Limited Partnership | 354,816 | $39.4M | 0.06% | −35,853−9.2% | Reduced |
| Bank of America Corp | 325,470 | $36.1M | 0.00% | −303,197−48.2% | Reduced |
| OrbiMed Advisors LLC | 322,900 | $35.9M | 0.68% | +8,800+2.8% | Added |
| Millennium Management LLC | 316,719 | $35.2M | 0.02% | −135,106−29.9% | Reduced |
| Silverarc Capital Management, LLC | 311,461 | $34.6M | 3.85% | +5,461+1.8% | Added |
| Voya Investment Management LLC | 272,974 | $30.3M | 0.03% | +39,164+16.8% | Added |
| Capital World Investors | 221,450 | $24.6M | 0.00% | +105,757+91.4% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 203,618 | $22.6M | 0.52% | +203,618 | New |
| Nuveen, LLC | 203,078 | $22.5M | 0.01% | +85,702+73.0% | Added |
| BNP Paribas Arbitrage, SA | 197,374 | $21.9M | 0.01% | −50,502−20.4% | Reduced |
| Kennedy Capital Management, Inc. | 193,215 | $21.5M | 0.38% | +127,397+193.6% | Added |
| Assenagon Asset Management S.A. | 186,491 | $20.7M | 0.03% | +186,491 | New |
| Schroder Investment Management Group | 160,518 | $17.7M | 0.01% | +28,844+21.9% | Added |
| First Turn Management, LLC | 154,018 | $17.1M | 1.83% | +154,018 | New |
| New York State Common Retirement Fund | 148,152 | $16.4M | 0.02% | +22,945+18.3% | Added |
| UBS Group AG | 144,378 | $16.0M | 0.00% | −87,272−37.7% | Reduced |
| Nicholas Investment Partners, LP | 139,270 | $15.5M | 0.87% | +139,270 | New |
| ADAR1 Capital Management, LLC | 136,158 | $15.1M | 0.71% | −75,292−35.6% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 135,867 | $15.1M | 0.03% | −15,975−10.5% | Reduced |
| Qube Research & Technologies Ltd | 134,410 | $14.9M | 0.02% | −143,533−51.6% | Reduced |
| NEXTBio Capital Management LP | 131,758 | $14.6M | 6.73% | +5,680+4.5% | Added |
| Driehaus Capital Management LLC | 129,285 | $14.4M | 0.08% | −307,261−70.4% | Reduced |
| SummitTX Capital, L.P. | 126,401 | $14.0M | 0.37% | −39,198−23.7% | Reduced |
| Logos Global Management LP | 125,000 | $13.9M | 0.60% | −325,000−72.2% | Reduced |
| Opaleye Management Inc. | 122,500 | $13.6M | 1.23% | −500−0.4% | Reduced |
| Segall Bryant & Hamill, LLC | 121,866 | $13.5M | 0.16% | +121,866 | New |
| Deutsche Bank AG | 115,232 | $12.8M | 0.00% | −26,369−18.6% | Reduced |
| Longaeva Partners L.P. | 110,074 | $12.2M | 0.35% | +110,074 | New |
| Swiss National Bank | 109,700 | $12.2M | 0.01% | −2,500−2.2% | Reduced |
| PFM Health Sciences, LP | 101,550 | $11.3M | 0.98% | −35,071−25.7% | Reduced |
| Standard Life Aberdeen plc | 94,946 | $10.5M | 0.01% | +15,589+19.6% | Added |
| Axiom Investors LLC | 86,880 | $9.65M | 0.08% | −4,869−5.3% | Reduced |
| Russell Investments Group, Ltd. | 86,709 | $9.63M | 0.01% | −29,003−25.1% | Reduced |
| First Light Asset Management, LLC | 85,765 | $9.52M | 0.58% | −1,416−1.6% | Reduced |
| Algert Global LLC | 83,431 | $9.26M | 0.11% | +24,918+42.6% | Added |
| Granahan Investment Management Inc | 83,270 | $9.25M | 0.33% | +5,561+7.2% | Added |
| Neuberger Berman Group LLC | 83,035 | $9.22M | 0.01% | +9,601+13.1% | Added |
| Sphera Funds Management Ltd. | 80,400 | $8.93M | 1.28% | +80,400 | New |
| WCM Investment Management, LLC | 80,552 | $8.86M | 0.02% | −68−0.1% | Reduced |
| Atom Investors LP | 73,465 | $8.16M | 0.73% | +16,465+28.9% | Added |
| Silvercrest Asset Management Group LLC | 73,432 | $8.15M | 0.05% | +26,545+56.6% | Added |
| Rhumbline Advisers | 73,333 | $8.14M | 0.01% | +3,475+5.0% | Added |
| Wells Fargo & Company | 72,147 | $8.01M | 0.00% | +38,039+111.5% | Added |
| Prudential Financial Inc | 69,145 | $7.68M | 0.01% | +38,955+129.0% | Added |
| Capital Fund Management S.A. | 68,548 | $7.61M | 0.05% | +68,548 | New |
| Renaissance Technologies LLC | 68,281 | $7.58M | 0.01% | −189,730−73.5% | Reduced |
| Picton Mahoney Asset Management | 65,880 | $7.31M | 0.07% | +15,508+30.8% | Added |
| California State Teachers Retirement System | 64,031 | $7.11M | 0.01% | −1,775−2.7% | Reduced |
| Blue Owl Capital Holdings LP | 61,455 | $6.82M | 1.04% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 61,147 | $6.79M | 0.06% | +43,372+244.0% | Added |
| AQR Capital Management LLC | 59,208 | $6.57M | 0.00% | −71−0.1% | Reduced |
| Citigroup Inc | 58,347 | $6.48M | 0.00% | +46,011+373.0% | Added |
| Raymond James Financial Inc | 58,069 | $6.45M | 0.00% | +8,149+16.3% | Added |
| Manufacturers Life Insurance Company, The | 57,170 | $6.35M | 0.00% | +6,401+12.6% | Added |
| Trexquant Investment LP | 56,248 | $6.25M | 0.04% | +56,248 | New |