Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 98
- +1 vs. Q3 2021
- Shares held
- 48.5M
- +497.7K (+1.0%) vs. Q3 2021
- Total value
- $483.6M
- −$142.8M (−22.8%) vs. Q3 2021
- New holders
- 13
- 39 more added
- Sold out
- 12
- 29 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 6,256,991 | $62.4M | 0.04% | +75,900+1.2% | Added |
| NEA Management Company, LLC | 4,912,306 | $49.0M | 0.99% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 4,871,067 | $48.6M | 0.86% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 3,863,239 | $38.6M | 0.19% | 00.0% | Unchanged |
| BlackRock Inc. | 3,328,061 | $33.2M | 0.00% | −33,925−1.0% | Reduced |
| Janus Henderson Group PLC | 3,133,935 | $31.3M | 0.01% | −48,447−1.5% | Reduced |
| Goldman Sachs Group Inc | 3,096,548 | $30.9M | 0.01% | +191,229+6.6% | Added |
| Federated Hermes, Inc. | 2,803,335 | $28.0M | 0.05% | −207,718−6.9% | Reduced |
| Vanguard Group Inc | 2,323,521 | $23.2M | 0.00% | +10,443+0.5% | Added |
| State Street Corp | 1,931,090 | $19.3M | 0.00% | −293,627−13.2% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 1,867,467 | $18.6M | 0.39% | −122,158−6.1% | Reduced |
| Franklin Resources Inc | 1,536,872 | $15.3M | 0.01% | +1,368,789+814.4% | Added |
| MPM Asset Management LLC | 909,258 | $9.07M | 1.96% | 00.0% | Unchanged |
| Wellington Management Group LLP | 745,883 | $7.44M | 0.00% | −100,069−11.8% | Reduced |
| Geode Capital Management, LLC | 714,028 | $7.13M | 0.00% | +46,370+6.9% | Added |
| Assenagon Asset Management S.A. | 684,746 | $6.83M | 0.03% | +182,476+36.3% | Added |
| Rock Springs Capital Management LP | 627,180 | $6.26M | 0.14% | +15,000+2.5% | Added |
| FMR LLC | 546,320 | $5.45M | 0.00% | +463,042+556.0% | Added |
| Northern Trust Corp | 429,071 | $4.28M | 0.00% | +8,637+2.1% | Added |
| Samsara BioCapital, LLC | 345,293 | $3.45M | 0.69% | +45,000+15.0% | Added |
| Millennium Management LLC | 313,704 | $3.13M | 0.00% | +96,780+44.6% | Added |
| Charles Schwab Investment Management Inc | 289,106 | $2.89M | 0.00% | +22,744+8.5% | Added |
| Morgan Stanley | 268,363 | $2.68M | 0.00% | +62,897+30.6% | Added |
| Nuveen Asset Management, LLC | 202,378 | $2.02M | 0.00% | −11,604−5.4% | Reduced |
| Endurant Capital Management LP | 197,462 | $1.97M | 0.53% | +197,462 | New |
| Dimensional Fund Advisors LP | 158,869 | $1.59M | 0.00% | −21,576−12.0% | Reduced |
| Bank of New York Mellon Corp | 156,918 | $1.57M | 0.00% | +495+0.3% | Added |
| Rice Hall James & Associates, LLC | 127,546 | $1.27M | 0.05% | −22,174−14.8% | Reduced |
| Bank of America Corp | 122,635 | $1.22M | 0.00% | −81,828−40.0% | Reduced |
| Rafferty Asset Management, LLC | 111,594 | $1.11M | 0.01% | +28,740+34.7% | Added |
| UBS Group AG | 103,580 | $1.03M | 0.00% | +22,610+27.9% | Added |
| Citigroup Inc | 96,017 | $958.0K | 0.00% | +36,291+60.8% | Added |
| SG Americas Securities, LLC | 91,659 | $915.0K | 0.01% | −17,644−16.1% | Reduced |
| Swiss National Bank | 77,700 | $775.0K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 73,913 | $738.0K | 0.00% | −60,673−45.1% | Reduced |
| Susquehanna International Group, LLP | 64,468 | $643.0K | 0.00% | +11,265+21.2% | Added |
| Rhumbline Advisers | 60,537 | $604.0K | 0.00% | −750−1.2% | Reduced |
| Caxton Associates LP | 59,397 | $593.0K | 0.08% | +59,397 | New |
| California State Teachers Retirement System | 53,489 | $534.0K | 0.00% | +997+1.9% | Added |
| Barclays PLC | 53,469 | $533.0K | 0.00% | +18,175+51.5% | Added |
| Hennion & Walsh Asset Management, Inc. | 52,212 | $521.0K | 0.03% | +3,262+6.7% | Added |
| Norges Bank | 51,161 | $511.0K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 48,400 | $483.0K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 46,400 | $463.0K | 0.00% | +23,648+103.9% | Added |
| Alliancebernstein L.P. | 44,800 | $447.0K | 0.00% | +3,200+7.7% | Added |
| BNP Paribas Arbitrage, SA | 37,374 | $373.0K | 0.00% | +26,466+242.6% | Added |
| New York State Common Retirement Fund | 30,576 | $305.0K | 0.00% | −4,589−13.0% | Reduced |
| Tudor Investment Corp Et Al | 29,478 | $294.0K | 0.01% | +29,478 | New |
| UBS Asset Management Americas Inc | 29,431 | $293.7K | 0.00% | +4,216+16.7% | Added |
| Credit Suisse AG | 28,417 | $283.0K | 0.00% | +2,837+11.1% | Added |
| ACT Capital Management, LLC | 27,500 | $274.0K | 0.20% | −3,500−11.3% | Reduced |
| Deutsche Bank AG | 26,754 | $267.0K | 0.00% | +115+0.4% | Added |
| HRT Financial LP | 25,918 | $258.0K | 0.00% | +25,918 | New |
| Manufacturers Life Insurance Company, The | 24,695 | $246.0K | 0.00% | +272+1.1% | Added |
| Invesco Ltd. | 24,248 | $243.0K | 0.00% | −3,085−11.3% | Reduced |
| American International Group, Inc. | 23,411 | $234.0K | 0.00% | −700−2.9% | Reduced |
| JPMorgan Chase & Co | 22,280 | $223.0K | 0.00% | −221−1.0% | Reduced |
| Wells Fargo & Company | 21,143 | $210.0K | 0.00% | +18,930+855.4% | Added |
| Engineers Gate Manager LP | 20,633 | $206.0K | 0.01% | +20,633 | New |
| Virtus ETF Advisers LLC | 17,290 | $173.0K | 0.07% | +7,061+69.0% | Added |
| Voya Investment Management LLC | 17,216 | $172.0K | 0.00% | −43−0.2% | Reduced |
| ProShare Advisors LLC | 16,707 | $168.0K | 0.00% | +332+2.0% | Added |
| Hantz Financial Services, Inc. | 16,869 | $168.0K | 0.00% | +10,986+186.7% | Added |
| Parametric Portfolio Associates LLC | 16,190 | $162.0K | 0.00% | −2,660−14.1% | Reduced |
| ExodusPoint Capital Management, LP | 15,475 | $154.0K | 0.00% | +3,874+33.4% | Added |
| MetLife Investment Management | 15,372 | $153.4K | 0.00% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 14,661 | $146.0K | 0.00% | +14,661 | New |
| State Board of Administration of Florida Retirement System | 13,990 | $140.0K | 0.00% | +146+1.1% | Added |
| Legal & General Group Plc | 13,263 | $132.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 8,531 | $85.0K | 0.00% | +3,951+86.3% | Added |
| Macquarie Group Ltd | 8,155 | $81.0K | 0.00% | +464+6.0% | Added |
| Exane Derivatives | 7,886 | $78.7K | 0.02% | +7,886 | New |
| Metropolitan Life Insurance Co | 7,534 | $75.2K | 0.00% | −1,259−14.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 5,398 | $54.0K | 0.00% | −173−3.1% | Reduced |
| Ensign Peak Advisors, Inc | 5,090 | $51.0K | 0.00% | +5,090 | New |
| Aquatic Capital Management LLC | 4,000 | $40.0K | 0.08% | +4,000 | New |
| Ameritas Investment Partners, Inc. | 3,454 | $34.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 3,348 | $33.0K | 0.00% | −1,056−24.0% | Reduced |
| US Bancorp | 3,164 | $32.0K | 0.00% | +3,068+3,195.8% | Added |
| Nisa Investment Advisors, LLC | 3,600 | $27.0K | 0.00% | +3,050+554.5% | Added |
| Tower Research Capital LLC (TRC) | 2,518 | $25.0K | 0.00% | −679−21.2% | Reduced |
| Sierra Capital LLC | 2,400 | $24.0K | 0.00% | −1,200−33.3% | Reduced |
| Great West Life Assurance Co | 2,363 | $23.0K | 0.00% | 00.0% | Unchanged |
| FourThought Financial, LLC | 2,159 | $22.0K | 0.00% | +1,589+278.8% | Added |
| Koshinski Asset Management, Inc. | 1,060 | $10.6K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 350 | $3.00K | 0.00% | 00.0% | Unchanged |
| Bessemer Group Inc | 251 | $3.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 210 | $2.00K | 0.00% | −600−74.1% | Reduced |
| Group One Trading, L.P. | 241 | $2.00K | 0.00% | 00.0% | Unchanged |
| State of Wyoming | 208 | $2.00K | 0.00% | −11−5.0% | Reduced |
| Daiwa Securities Group Inc. | 172 | $2.00K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 200 | $2.00K | 0.00% | +200 | New |
| Signaturefd, LLC | 111 | $1.00K | 0.00% | −1,853−94.3% | Reduced |
| Newbridge Financial Services Group, Inc. | 65 | $1.00K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 83 | $1.00K | 0.00% | +83 | New |
| Parallel Advisors, LLC | 50 | $0 | 0.00% | −131−72.4% | Reduced |
| Ellevest, Inc. | 10 | $0 | 0.00% | +10 | New |
| Beaird Harris Wealth Management, LLC | 49 | $0 | 0.00% | +49 | New |
| Gilder Gagnon Howe & Co LLC | 0 | $0 | 0.00% | −1,496,424−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −49,845−100.0% | Sold out |