Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 203
- +28 vs. Q3 2024
- Shares held
- 64.9M
- −2.70M (−4.0%) vs. Q3 2024
- Total value
- $3.63B
- +$92.1M (+2.6%) vs. Q3 2024
- New holders
- 52
- 66 more added
- Sold out
- 24
- 53 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 6,950,715 | $389.1M | 0.01% | +61,457+0.9% | Added |
| Primecap Management Co | 6,571,190 | $367.9M | 0.28% | −645,721−8.9% | Reduced |
| Ra Capital Management, L.P. | 6,084,412 | $340.6M | 4.53% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 6,084,249 | $340.6M | 3.64% | −314,117−4.9% | Reduced |
| Perceptive Advisors LLC | 3,680,473 | $206.0M | 5.74% | +120,259+3.4% | Added |
| Vanguard Group Inc | 3,442,600 | $192.7M | 0.00% | −5,311−0.2% | Reduced |
| NEA Management Company, LLC | 2,909,956 | $162.9M | 9.19% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 1,869,808 | $104.7M | 4.34% | −547,144−22.6% | Reduced |
| State Street Corp | 1,840,870 | $103.1M | 0.00% | −152,296−7.6% | Reduced |
| Goldman Sachs Group Inc | 1,812,206 | $101.4M | 0.02% | −2,067,590−53.3% | Reduced |
| Federated Hermes, Inc. | 1,549,635 | $86.7M | 0.19% | −114,265−6.9% | Reduced |
| Polar Capital Holdings Plc | 1,500,000 | $84.0M | 0.47% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 1,290,975 | $72.3M | 0.60% | −8,515−0.7% | Reduced |
| Geode Capital Management, LLC | 1,255,799 | $70.3M | 0.01% | −3890.0% | Reduced |
| Janus Henderson Group PLC | 1,219,554 | $68.3M | 0.03% | +621,432+103.9% | Added |
| Alkeon Capital Management LLC | 1,167,700 | $65.4M | 0.38% | 00.0% | Unchanged |
| Rock Springs Capital Management LP | 1,162,718 | $65.1M | 2.48% | −65,375−5.3% | Reduced |
| Checkpoint Capital L.P. | 727,982 | $40.8M | 20.74% | +64,601+9.7% | Added |
| Marshall Wace, LLP | 692,803 | $38.8M | 0.05% | +286,188+70.4% | Added |
| Price T Rowe Associates Inc | 685,152 | $38.4M | 0.00% | +134,622+24.5% | Added |
| Hood River Capital Management LLC | 643,691 | $36.0M | 0.53% | +29,093+4.7% | Added |
| Loomis Sayles & Co L P | 618,485 | $34.6M | 0.04% | −18,143−2.8% | Reduced |
| Morgan Stanley | 560,087 | $31.4M | 0.00% | +95,483+20.6% | Added |
| Northern Trust Corp | 545,314 | $30.5M | 0.00% | +46,848+9.4% | Added |
| Opaleye Management Inc. | 500,000 | $28.0M | 4.90% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 440,250 | $24.6M | 0.00% | +6,384+1.5% | Added |
| OrbiMed Advisors LLC | 400,000 | $22.4M | 0.46% | −35,900−8.2% | Reduced |
| Cormorant Asset Management, LP | 400,000 | $22.4M | 1.23% | 00.0% | Unchanged |
| Sofinnova Investments, Inc. | 397,428 | $22.2M | 1.63% | +120,750+43.6% | Added |
| Voloridge Investment Management, LLC | 380,537 | $21.3M | 0.08% | +27,214+7.7% | Added |
| Pictet Asset Management Holding SA | 375,349 | $21.0M | 0.02% | +46,010+14.0% | Added |
| Candriam Luxembourg S.C.A. | 332,392 | $18.6M | 0.11% | −62,985−15.9% | Reduced |
| Invesco Ltd. | 302,846 | $17.0M | 0.00% | +38,429+14.5% | Added |
| Silverarc Capital Management, LLC | 273,896 | $15.3M | 3.43% | +18,318+7.2% | Added |
| Franklin Resources Inc | 268,205 | $15.0M | 0.00% | +8,789+3.4% | Added |
| JPMorgan Chase & Co | 264,585 | $14.8M | 0.00% | +182,993+224.3% | Added |
| UBS Group AG | 254,264 | $14.2M | 0.00% | +177,630+231.8% | Added |
| UBS Asset Management Americas Inc | 218,544 | $12.2M | 0.00% | −6,829−3.0% | Reduced |
| StemPoint Capital LP | 208,016 | $11.6M | 2.92% | +166,748+404.1% | Added |
| Norges Bank | 205,649 | $11.5M | 0.00% | +139,373+210.3% | Added |
| Samsara BioCapital, LLC | 172,647 | $9.66M | 1.33% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 160,651 | $8.99M | 0.03% | +58,005+56.5% | Added |
| Integral Health Asset Management, LLC | 150,000 | $8.40M | 0.74% | +150,000 | New |
| Bank of New York Mellon Corp | 148,246 | $8.30M | 0.00% | −680−0.5% | Reduced |
| Nuveen Asset Management, LLC | 146,903 | $8.22M | 0.00% | −972−0.7% | Reduced |
| Walleye Capital LLC | 144,342 | $8.08M | 0.08% | +144,342 | New |
| Balyasny Asset Management LLC | 138,363 | $7.75M | 0.02% | +138,363 | New |
| Barclays PLC | 135,397 | $7.58M | 0.00% | +29,000+27.3% | Added |
| First Trust Advisors LP | 118,337 | $6.62M | 0.01% | +47,575+67.2% | Added |
| FMR LLC | 113,109 | $6.33M | 0.00% | +62,814+124.9% | Added |
| Lazard Asset Management LLC | 106,261 | $5.95M | 0.01% | +106,261 | New |
| Bank of America Corp | 104,488 | $5.85M | 0.00% | −1,762−1.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 99,447 | $5.57M | 0.25% | −1,514−1.5% | Reduced |
| Voya Investment Management LLC | 97,169 | $5.44M | 0.01% | −5,663−5.5% | Reduced |
| Qube Research & Technologies Ltd | 95,235 | $5.33M | 0.01% | +95,235 | New |
| Swiss National Bank | 90,200 | $5.05M | 0.00% | +900+1.0% | Added |
| BNP Paribas Arbitrage, SA | 85,249 | $4.77M | 0.00% | +70,824+491.0% | Added |
| Cinctive Capital Management LP | 82,755 | $4.63M | 0.25% | +82,755 | New |
| Rhumbline Advisers | 82,731 | $4.63M | 0.00% | +2,017+2.5% | Added |
| Standard Life Aberdeen plc | 80,517 | $4.51M | 0.01% | −32,287−28.6% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 76,084 | $4.26M | 0.01% | +76,084 | New |
| Diadema Partners LP | 75,000 | $4.20M | 4.73% | +75,000 | New |
| Citigroup Inc | 69,777 | $3.91M | 0.00% | +28,580+69.4% | Added |
| EAM Investors, LLC | 63,078 | $3.53M | 0.50% | +63,078 | New |
| Alliancebernstein L.P. | 61,470 | $3.44M | 0.00% | +1,900+3.2% | Added |
| Manufacturers Life Insurance Company, The | 59,969 | $3.36M | 0.00% | +11,266+23.1% | Added |
| Schonfeld Strategic Advisors LLC | 59,700 | $3.34M | 0.02% | +29,165+95.5% | Added |
| Jane Street Group, LLC | 58,415 | $3.27M | 0.01% | −50,771−46.5% | Reduced |
| EAM Global Investors LLC | 56,936 | $3.19M | 0.57% | +56,936 | New |
| Ameriprise Financial Inc | 53,367 | $2.99M | 0.00% | +11,480+27.4% | Added |
| Legal & General Group Plc | 51,803 | $2.90M | 0.00% | +951+1.9% | Added |
| Susquehanna International Group, LLP | 50,664 | $2.84M | 0.00% | +29,183+135.9% | Added |
| Rafferty Asset Management, LLC | 50,394 | $2.82M | 0.01% | −14,182−22.0% | Reduced |
| Artia Global Partners LP | 50,000 | $2.80M | 1.13% | +50,000 | New |
| Alps Advisors Inc | 49,700 | $2.78M | 0.02% | +49,700 | New |
| Nan Fung Group Holdings Ltd | 49,120 | $2.75M | 2.35% | 00.0% | Unchanged |
| Deutsche Bank AG | 48,745 | $2.73M | 0.00% | +15,481+46.5% | Added |
| Wedge Capital Management L L P | 48,411 | $2.71M | 0.05% | −433−0.9% | Reduced |
| D. E. Shaw & Co., Inc. | 48,198 | $2.70M | 0.00% | +43,904+1,022.4% | Added |
| TD Asset Management Inc | 47,800 | $2.68M | 0.00% | +16,000+50.3% | Added |
| PDT Partners, LLC | 43,583 | $2.44M | 0.22% | +32,083+279.0% | Added |
| California State Teachers Retirement System | 43,533 | $2.44M | 0.00% | −383−0.9% | Reduced |
| Algert Global LLC | 41,551 | $2.33M | 0.05% | −12,620−23.3% | Reduced |
| Citadel Advisors LLC | 40,419 | $2.26M | 0.00% | −62,359−60.7% | Reduced |
| HighVista Strategies LLC | 37,426 | $2.10M | 0.78% | 00.0% | Unchanged |
| Wells Fargo & Company | 37,324 | $2.09M | 0.00% | +7,850+26.6% | Added |
| Principal Financial Group Inc | 36,884 | $2.06M | 0.00% | +4,298+13.2% | Added |
| State of New Jersey Common Pension Fund D | 35,004 | $1.96M | 0.01% | +35,004 | New |
| American Century Companies Inc | 33,766 | $1.89M | 0.00% | +33,766 | New |
| SEI Investments Co | 33,522 | $1.88M | 0.00% | +4,501+15.5% | Added |
| MetLife Investment Management | 33,498 | $1.88M | 0.01% | +1,846+5.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 33,156 | $1.86M | 0.00% | +654+2.0% | Added |
| State of Wisconsin Investment Board | 32,262 | $1.81M | 0.00% | −191−0.6% | Reduced |
| ADAR1 Capital Management, LLC | 30,941 | $1.73M | 0.36% | +30,941 | New |
| Harbor Capital Advisors, Inc. | 30,252 | $1.69M | 0.07% | −11,116−26.9% | Reduced |
| Intech Investment Management LLC | 28,092 | $1.57M | 0.02% | +15,706+126.8% | Added |
| Corebridge Financial, Inc. | 27,220 | $1.52M | 0.01% | −2,054−7.0% | Reduced |
| Wellington Management Group LLP | 25,555 | $1.43M | 0.00% | −2,161−7.8% | Reduced |
| Crestline Management, LP | 25,062 | $1.40M | 0.05% | +6,064+31.9% | Added |
| Bellevue Group AG | 23,596 | $1.32M | 0.03% | +7,896+50.3% | Added |