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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q4 2024

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
+28 vs. Q3 2024
Shares held
64.9M
−2.70M (−4.0%) vs. Q3 2024
Total value
$3.63B
+$92.1M (+2.6%) vs. Q3 2024
New holders
52
66 more added
Sold out
24
53 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 203 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 305 institutions
Value heldQ4 2024: $3.63B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026305$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2024.

Institutions holding RYTM in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Fiduciary Trust Co20,000$1.12M0.01%00.0%Unchanged
Bryce Point Capital, LLC19,607$1.10M0.32%+19,607New
Stifel Financial Corp19,516$1.09M0.00%−326−1.6%Reduced
Persistent Asset Partners Ltd18,312$1.09M0.93%+18,312New
Engineers Gate Manager LP19,183$1.07M0.02%+19,183New
Castleark Management LLC18,390$1.03M0.04%−870−4.5%Reduced
ProShare Advisors LLC18,328$1.03M0.00%+4,370+31.3%Added
Ensign Peak Advisors, Inc17,659$988.6K0.00%00.0%Unchanged
Victory Capital Management Inc17,152$960.2K0.00%−1,034−5.7%Reduced
Comerica Bank17,113$958.0K0.00%−447−2.5%Reduced
Handelsbanken Fonder AB17,021$953.0K0.00%−2,300−11.9%Reduced
New York State Common Retirement Fund16,850$943.3K0.00%00.0%Unchanged
HSBC Holdings PLC16,287$921.2K0.00%+16,287New
STRS Ohio16,400$918.1K0.00%+10,200+164.5%Added
Quantinno Capital Management LP16,120$902.4K0.01%00.0%Unchanged
AQR Capital Management LLC15,857$887.7K0.00%−16,952−51.7%Reduced
Millennium Management LLC15,259$854.2K0.00%−21,718−58.7%Reduced
Tudor Investment Corp Et Al15,245$853.4K0.01%+15,245New
State Board of Administration of Florida Retirement System14,670$821.2K0.00%00.0%Unchanged
Teacher Retirement System of Texas13,586$761.0K0.00%+2,117+18.5%Added
Arizona State Retirement System13,287$743.8K0.00%+119+0.9%Added
Two Sigma Advisers, LP13,100$733.3K0.00%+300+2.3%Added
China Universal Asset Management Co., Ltd.13,031$729.5K0.07%+1,273+10.8%Added
Exchange Traded Concepts, LLC12,375$692.8K0.01%−2,682−17.8%Reduced
Police & Firemen's Retirement System of New Jersey11,655$652.4K0.01%+11,655New
Atom Investors LP11,605$649.6K0.08%+11,605New
Great West Life Assurance Co11,578$648.0K0.00%00.0%Unchanged
Profund Advisors LLC10,481$586.7K0.02%−2,877−21.5%Reduced
Creative Planning10,224$572.3K0.00%+1,630+19.0%Added
Cannon Financial Strategists, Inc.10,000$559.8K0.10%+10,000New
KLP Kapitalforvaltning AS9,300$520.6K0.00%+9,300New
Aquatic Capital Management LLC9,223$516.3K0.01%+9,223New
Zurcher Kantonalbank (Zurich Cantonalbank)9,034$505.7K0.00%−67−0.7%Reduced
Verition Fund Management LLC8,037$449.9K0.00%+8,037New
Trexquant Investment LP7,798$436.5K0.01%+7,798New
XTX Topco Ltd7,605$425.7K0.04%+7,605New
Omers Administration Corp7,600$425.4K0.00%+7,600New
Advisors Asset Management, Inc.7,074$396.0K0.01%+7,074New
Farringdon Capital, Ltd.6,854$383.7K0.16%+6,854New
Gotham Asset Management, LLC6,786$379.9K0.00%−2,685−28.3%Reduced
Jain Global LLC6,700$375.1K0.01%+6,700New
Virtus ETF Advisers LLC6,280$351.6K0.14%−1,143−15.4%Reduced
Allianz Asset Management GmbH6,100$341.5K0.00%+2,000+48.8%Added
Connor, Clark & Lunn Investment Management Ltd.6,089$340.9K0.00%+6,089New
Y-Intercept (Hong Kong) Ltd5,866$328.4K0.02%+5,866New
Jasper Ridge Partners, L.P.5,639$315.7K0.01%00.0%Unchanged
Ameritas Investment Partners, Inc.5,546$310.5K0.01%00.0%Unchanged
Public Employees Retirement Association of Colorado5,463$306.0K0.00%00.0%Unchanged
JGP Global Gestao de Recursos Ltda.5,378$301.1K0.69%−51,000−90.5%Reduced
Dark Forest Capital Management LP5,211$291.7K0.04%+5,211New
CIBC World Markets Corp5,123$286.8K0.00%+5,123New
Bridgefront Capital, LLC4,604$257.7K0.09%+4,604New
Tower Research Capital LLC (TRC)4,539$254.1K0.01%+4,161+1,100.8%Added
Mariner, LLC4,525$253.6K0.00%+4,525New
Mackenzie Financial Corp4,343$243.1K0.00%00.0%Unchanged
Texas Treasury Safekeeping Trust Co4,230$237.0K0.01%00.0%Unchanged
LPL Financial LLC4,175$233.7K0.00%−4,323−50.9%Reduced
Prudential Financial Inc4,155$233.6K0.00%−104−2.4%Reduced
Xponance, Inc.4,168$233.3K0.00%+4,168New
Raymond James Financial Inc3,892$217.9K0.00%+3,892New
Chicago Partners Investment Group LLC3,696$213.9K0.01%−1,029−21.8%Reduced
Freestone Capital Holdings, LLC3,700$207.1K0.01%+3,700New
Simplex Trading, LLC2,475$138.0K0.00%+2,475New
KBC Group NV2,251$126.0K0.00%+988+78.2%Added
Mirae Asset Global Investments Co., Ltd.2,048$113.8K0.00%−163−7.4%Reduced
ZRC Wealth Management, LLC1,971$110.3K0.05%00.0%Unchanged
Amalgamated Bank1,875$105.0K0.00%00.0%Unchanged
Whittier Trust Co1,760$98.5K0.00%−240−12.0%Reduced
CWM, LLC1,344$75.0K0.00%+417+45.0%Added
GF Fund Management Co. Ltd.1,290$72.2K0.00%+1,290New
Nisa Investment Advisors, LLC1,285$71.9K0.00%−64,955−98.1%Reduced
Royal Bank of Canada1,214$68.0K0.00%−5,071−80.7%Reduced
ORG Wealth Partners, LLC1,206$67.5K0.02%00.0%Unchanged
State of Wyoming1,084$60.7K0.01%+1,084New
Natixis997$55.8K0.00%−10,190−91.1%Reduced
Russell Investments Group, Ltd.997$55.8K0.00%+3+0.3%Added
R Squared Ltd780$43.7K0.04%+780New
Advisor Group Holdings, Inc.673$37.7K0.00%+5+0.7%Added
SBI Securities Co., Ltd.666$37.3K0.00%+666New
Raleigh Capital Management Inc.500$28.0K0.01%+500New
SRS Capital Advisors, Inc.454$25.4K0.00%+400+740.7%Added
Ameriflex Group, Inc.360$21.4K0.01%+360New
The PNC Financial Services Group, Inc.304$17.0K0.00%+181+147.2%Added
Jones Financial Companies LLLP231$12.9K0.00%00.0%Unchanged
Signaturefd, LLC222$12.4K0.00%+9+4.2%Added
GAMMA Investing LLC201$11.3K0.00%+80+66.1%Added
Daiwa Securities Group Inc.203$11.0K0.00%−24−10.6%Reduced
Smartleaf Asset Management LLC193$10.9K0.00%+73+60.8%Added
US Bancorp141$7.89K0.00%00.0%Unchanged
Truvestments Capital LLC138$7.72K0.00%00.0%Unchanged
Lindbrook Capital, LLC126$7.05K0.00%00.0%Unchanged
Rothschild Investment LLC65$3.64K0.00%+55+550.0%Added
Sterling Capital Management LLC56$3.13K0.00%00.0%Unchanged
Bessemer Group Inc30$2.00K0.00%00.0%Unchanged
Parallel Advisors, LLC19$1.06K0.00%00.0%Unchanged
Covestor Ltd10$1.00K0.00%+7+233.3%Added
Farther Finance Advisors, LLC14$7840.00%00.0%Unchanged
CVA Family Office, LLC12$6720.00%00.0%Unchanged
EverSource Wealth Advisors, LLC12$6720.00%+12New
Whipplewood Advisors, LLC11$6160.00%+11New