Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 167
- −2 vs. Q4 2023
- Shares held
- 68.0M
- +1.33M (+2.0%) vs. Q4 2023
- Total value
- $2.95B
- −$119.7M (−3.9%) vs. Q4 2023
- New holders
- 25
- 63 more added
- Sold out
- 27
- 54 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 7,747,591 | $335.7M | 0.25% | −305,057−3.8% | Reduced |
| BlackRock Inc. | 6,529,646 | $282.9M | 0.01% | +177,896+2.8% | Added |
| Baker Bros. Advisors LP | 6,398,365 | $277.2M | 3.48% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 5,330,412 | $231.0M | 2.94% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 5,111,601 | $221.5M | 0.05% | +63,667+1.3% | Added |
| Vanguard Group Inc | 3,304,146 | $143.2M | 0.00% | +77,208+2.4% | Added |
| Perceptive Advisors LLC | 3,268,579 | $141.6M | 2.50% | +1,114,469+51.7% | Added |
| State Street Corp | 3,013,838 | $130.6M | 0.01% | +807,820+36.6% | Added |
| NEA Management Company, LLC | 2,909,956 | $126.1M | 7.83% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 2,190,179 | $94.9M | 4.00% | −181,125−7.6% | Reduced |
| Federated Hermes, Inc. | 1,661,097 | $72.0M | 0.17% | −649,858−28.1% | Reduced |
| Rock Springs Capital Management LP | 1,522,893 | $66.0M | 1.68% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 1,500,000 | $65.0M | 0.39% | −250,000−14.3% | Reduced |
| Pictet Asset Management Holding SA | 1,211,679 | $52.5M | 0.06% | +47,718+4.1% | Added |
| Geode Capital Management, LLC | 1,180,705 | $51.2M | 0.00% | +61,576+5.5% | Added |
| Commodore Capital LP | 1,050,000 | $45.5M | 3.04% | −500,000−32.3% | Reduced |
| Driehaus Capital Management LLC | 855,505 | $37.1M | 0.37% | +256,600+42.8% | Added |
| Checkpoint Capital L.P. | 825,500 | $35.8M | 23.91% | +95,500+13.1% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 730,643 | $31.7M | 0.11% | +578,800+381.2% | Added |
| OrbiMed Advisors LLC | 704,842 | $30.5M | 0.60% | +168,200+31.3% | Added |
| Janus Henderson Group PLC | 621,427 | $26.9M | 0.01% | −465−0.1% | Reduced |
| Canada Pension Plan Investment Board | 577,000 | $25.0M | 0.03% | +310,000+116.1% | Added |
| Cormorant Asset Management, LP | 550,000 | $23.8M | 1.05% | 00.0% | Unchanged |
| Opaleye Management Inc. | 515,000 | $22.3M | 4.86% | −95,000−15.6% | Reduced |
| Northern Trust Corp | 502,855 | $21.8M | 0.00% | +1,761+0.4% | Added |
| Price T Rowe Associates Inc | 481,533 | $20.9M | 0.00% | −90,764−15.9% | Reduced |
| Voloridge Investment Management, LLC | 473,455 | $20.5M | 0.07% | +110,738+30.5% | Added |
| Charles Schwab Investment Management Inc | 406,745 | $17.6M | 0.00% | +9,060+2.3% | Added |
| National Bank of Canada | 367,517 | $14.4M | 0.03% | +128,517+53.8% | Added |
| Assenagon Asset Management S.A. | 285,651 | $12.4M | 0.03% | −15,985−5.3% | Reduced |
| Lord, Abbett & Co. LLC | 281,157 | $12.2M | 0.04% | −2,361−0.8% | Reduced |
| Artisan Partners Limited Partnership | 271,421 | $11.8M | 0.02% | 00.0% | Unchanged |
| Franklin Resources Inc | 220,905 | $9.57M | 0.00% | +215,029+3,659.4% | Added |
| Rafferty Asset Management, LLC | 218,657 | $9.47M | 0.04% | +97,003+79.7% | Added |
| UBS Asset Management Americas Inc | 206,980 | $8.97M | 0.00% | −2,958−1.4% | Reduced |
| Wellington Management Group LLP | 193,523 | $8.39M | 0.00% | +53,721+38.4% | Added |
| Citigroup Inc | 190,520 | $8.26M | 0.01% | +136,220+250.9% | Added |
| Silverarc Capital Management, LLC | 183,776 | $7.96M | 2.23% | +9,528+5.5% | Added |
| Morgan Stanley | 182,870 | $7.92M | 0.00% | −48,786−21.1% | Reduced |
| Voya Investment Management LLC | 172,752 | $7.49M | 0.01% | +107,761+165.8% | Added |
| Samsara BioCapital, LLC | 172,647 | $7.48M | 1.16% | 00.0% | Unchanged |
| Woodline Partners LP | 172,207 | $7.46M | 0.07% | +97,357+130.1% | Added |
| UBS Group AG | 171,565 | $7.43M | 0.00% | +85,610+99.6% | Added |
| Bank of New York Mellon Corp | 167,838 | $7.27M | 0.00% | −12,384−6.9% | Reduced |
| Nisa Investment Advisors, LLC | 145,291 | $6.30M | 0.04% | +144,035+11,467.8% | Added |
| Nuveen Asset Management, LLC | 142,735 | $6.18M | 0.00% | −934−0.7% | Reduced |
| Barclays PLC | 127,536 | $5.53M | 0.00% | −123,879−49.3% | Reduced |
| Ghost Tree Capital, LLC | 125,000 | $5.42M | 1.74% | +125,000 | New |
| Bank of America Corp | 111,114 | $4.81M | 0.00% | +41,244+59.0% | Added |
| Squarepoint Ops LLC | 108,755 | $4.71M | 0.02% | +93,405+608.5% | Added |
| JGP Global Gestao de Recursos Ltda. | 105,814 | $4.58M | 2.95% | +100,126+1,760.3% | Added |
| Susquehanna International Group, LLP | 103,253 | $4.47M | 0.01% | +71,021+220.3% | Added |
| Swiss National Bank | 93,300 | $4.04M | 0.00% | +3,600+4.0% | Added |
| Clearbridge Investments, LLC | 90,004 | $3.90M | 0.00% | −1,154−1.3% | Reduced |
| Rice Hall James & Associates, LLC | 89,726 | $3.89M | 0.22% | +121+0.1% | Added |
| Invesco Ltd. | 88,205 | $3.82M | 0.00% | −47,526−35.0% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 86,967 | $3.77M | 0.20% | +20,259+30.4% | Added |
| Rhumbline Advisers | 76,724 | $3.32M | 0.00% | +3,552+4.9% | Added |
| Wedge Capital Management L L P | 73,873 | $3.20M | 0.05% | −2,634−3.4% | Reduced |
| AQR Capital Management LLC | 70,999 | $3.08M | 0.01% | +56,017+373.9% | Added |
| Algert Global LLC | 69,048 | $2.99M | 0.12% | +40,245+139.7% | Added |
| Jefferies Financial Group Inc. | 68,566 | $2.97M | 0.06% | −13,495−16.4% | Reduced |
| Castleark Management LLC | 63,900 | $2.77M | 0.12% | +63,900 | New |
| Altium Capital Management LP | 57,271 | $2.48M | 1.11% | +50,786+783.1% | Added |
| BNP Paribas Arbitrage, SA | 56,009 | $2.43M | 0.00% | −7,076−11.2% | Reduced |
| JPMorgan Chase & Co | 54,504 | $2.36M | 0.00% | −23,095−29.8% | Reduced |
| Alliancebernstein L.P. | 53,430 | $2.32M | 0.00% | −960−1.8% | Reduced |
| Norges Bank | 50,870 | $2.20M | 0.00% | +50,870 | New |
| Nan Fung Group Holdings Ltd | 49,120 | $2.13M | 1.97% | +9,050+22.6% | Added |
| California State Teachers Retirement System | 47,894 | $2.08M | 0.00% | −1,103−2.3% | Reduced |
| Manufacturers Life Insurance Company, The | 47,624 | $2.06M | 0.00% | +8,386+21.4% | Added |
| Legal & General Group Plc | 47,416 | $2.05M | 0.00% | +588+1.3% | Added |
| Exome Asset Management LLC | 45,603 | $1.98M | 1.69% | −26,600−36.8% | Reduced |
| Credit Suisse AG | 43,164 | $1.87M | 0.00% | +1,152+2.7% | Added |
| Alps Advisors Inc | 42,419 | $1.84M | 0.01% | +2,204+5.5% | Added |
| Atom Investors LP | 41,276 | $1.79M | 0.22% | +16,345+65.6% | Added |
| Profund Advisors LLC | 34,281 | $1.49M | 0.06% | +13,790+67.3% | Added |
| State of Wisconsin Investment Board | 33,304 | $1.44M | 0.00% | −4,110−11.0% | Reduced |
| Comerica Bank | 33,118 | $1.44M | 0.01% | −933−2.7% | Reduced |
| New York State Common Retirement Fund | 32,811 | $1.42M | 0.00% | −63−0.2% | Reduced |
| FMR LLC | 29,020 | $1.26M | 0.00% | −500,110−94.5% | Reduced |
| Deutsche Bank AG | 28,159 | $1.22M | 0.00% | +1,111+4.1% | Added |
| Stifel Financial Corp | 27,937 | $1.21M | 0.00% | −2,688−8.8% | Reduced |
| TD Asset Management Inc | 27,600 | $1.20M | 0.00% | −10,200−27.0% | Reduced |
| MetLife Investment Management | 27,123 | $1.18M | 0.01% | 00.0% | Unchanged |
| Wells Fargo & Company | 26,985 | $1.17M | 0.00% | −12,774−32.1% | Reduced |
| Graham Capital Management, L.P. | 26,436 | $1.15M | 0.03% | +26,436 | New |
| Jane Street Group, LLC | 26,318 | $1.14M | 0.00% | −158,041−85.7% | Reduced |
| American International Group, Inc. | 26,318 | $1.14M | 0.00% | +781+3.1% | Added |
| Harbor Capital Advisors, Inc. | 22,781 | $987.0K | 0.13% | +22,781 | New |
| Twinbeech Capital LP | 22,714 | $984.2K | 0.02% | +22,714 | New |
| Ameriprise Financial Inc | 20,980 | $909.1K | 0.00% | 00.0% | Unchanged |
| Fiduciary Trust Co | 20,000 | $866.6K | 0.01% | 00.0% | Unchanged |
| Marshall Wace, LLP | 19,750 | $855.8K | 0.00% | +19,750 | New |
| Ensign Peak Advisors, Inc | 17,659 | $765.2K | 0.00% | −891−4.8% | Reduced |
| Campbell & CO Investment Adviser LLC | 16,331 | $707.6K | 0.06% | +5,589+52.0% | Added |
| Handelsbanken Fonder AB | 15,921 | $690.0K | 0.00% | +3,600+29.2% | Added |
| Bayesian Capital Management, LP | 15,355 | $665.3K | 0.06% | +15,355 | New |
| Victory Capital Management Inc | 15,085 | $653.6K | 0.00% | −167,212−91.7% | Reduced |
| Parkwood LLC | 15,033 | $651.0K | 0.07% | +4,835+47.4% | Added |