Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.57B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2022
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 101
- +13 vs. Q2 2022
- Shares held
- 59.5M
- +13.5M (+29.5%) vs. Q2 2022
- Total value
- $1.45B
- +$1.25B (+657.6%) vs. Q2 2022
- New holders
- 35
- 36 more added
- Sold out
- 22
- 19 more reduced
2 institutions that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.57B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.32B |
| Q2 2025 | 227 | $4.22B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.86B |
| Q1 2024 | 167 | $2.98B |
| Q4 2023 | 169 | $3.09B |
| Q3 2023 | 144 | $1.57B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.09B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.48B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $484.7M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Primecap Management Co | 7,026,892 | $172.2M | 0.17% | +662,798+10.4% | Added |
| Federated Hermes, Inc. | 6,306,866 | $154.5M | 0.45% | +1,911,266+43.5% | Added |
| Baker Bros. Advisors LP | 6,062,702 | $148.5M | 0.97% | +1,937,640+47.0% | Added |
| Ra Capital Management, L.P. | 5,471,067 | $134.0M | 2.86% | +600,000+12.3% | Added |
| Goldman Sachs Group Inc | 4,777,178 | $117.0M | 0.03% | +1,616,792+51.2% | Added |
| NEA Management Company, LLC | 4,912,306 | $108.3M | 5.41% | 00.0% | Unchanged |
| BlackRock Inc. | 3,537,499 | $86.7M | 0.00% | +2,359,924+200.4% | Added |
| State Street Corp | 3,127,905 | $76.6M | 0.00% | +2,876,846+1,145.9% | Added |
| Vanguard Group Inc | 2,234,272 | $54.7M | 0.00% | +84,546+3.9% | Added |
| Frazier Life Sciences Management, L.P. | 1,894,000 | $46.4M | 3.57% | +1,894,000 | New |
| Rock Springs Capital Management LP | 1,760,865 | $43.1M | 1.11% | +357,567+25.5% | Added |
| Alkeon Capital Management LLC | 1,705,000 | $41.8M | 0.29% | +205,000+13.7% | Added |
| Janus Henderson Group PLC | 1,561,083 | $38.2M | 0.03% | −518,994−25.0% | Reduced |
| FMR LLC | 1,370,948 | $33.6M | 0.00% | +813,954+146.1% | Added |
| Opaleye Management Inc. | 810,000 | $19.8M | 8.20% | +448,000+123.8% | Added |
| Polar Capital Holdings Plc | 714,739 | $17.5M | 0.11% | +714,739 | New |
| Assenagon Asset Management S.A. | 470,410 | $11.5M | 0.05% | −219,310−31.8% | Reduced |
| Geode Capital Management, LLC | 388,112 | $9.51M | 0.00% | −11,682−2.9% | Reduced |
| Samsara BioCapital, LLC | 345,293 | $8.46M | 1.97% | 00.0% | Unchanged |
| Citigroup Inc | 272,187 | $6.67M | 0.01% | +269,921+11,911.8% | Added |
| Rafferty Asset Management, LLC | 262,288 | $6.43M | 0.07% | +262,288 | New |
| Voloridge Investment Management, LLC | 243,408 | $5.96M | 0.03% | +243,408 | New |
| Morgan Stanley | 230,197 | $5.64M | 0.00% | −200,550−46.6% | Reduced |
| Dimensional Fund Advisors LP | 223,131 | $5.47M | 0.00% | −30,110−11.9% | Reduced |
| Bank of America Corp | 218,409 | $5.35M | 0.00% | +169,297+344.7% | Added |
| Susquehanna International Group, LLP | 214,522 | $5.26M | 0.01% | +150,261+233.8% | Added |
| Charles Schwab Investment Management Inc | 204,269 | $5.00M | 0.00% | +31,539+18.3% | Added |
| EAM Investors, LLC | 198,699 | $4.87M | 1.06% | +198,699 | New |
| Walleye Capital LLC | 191,373 | $4.69M | 0.11% | +191,373 | New |
| Parkman Healthcare Partners LLC | 187,989 | $4.61M | 1.31% | +187,989 | New |
| D. E. Shaw & Co., Inc. | 183,069 | $4.49M | 0.01% | +146,577+401.7% | Added |
| Rice Hall James & Associates, LLC | 170,357 | $4.17M | 0.24% | +11,357+7.1% | Added |
| Altium Capital Management LP | 170,000 | $4.17M | 1.57% | +170,000 | New |
| Barclays PLC | 164,353 | $4.03M | 0.00% | +155,063+1,669.1% | Added |
| Wellington Management Group LLP | 153,213 | $3.75M | 0.00% | +67,648+79.1% | Added |
| Northern Trust Corp | 114,109 | $2.80M | 0.00% | +2,860+2.6% | Added |
| Cubist Systematic Strategies, LLC | 111,511 | $2.73M | 0.02% | +13,420+13.7% | Added |
| Swiss National Bank | 89,600 | $2.19M | 0.00% | +6,300+7.6% | Added |
| Tudor Investment Corp Et Al | 83,796 | $2.05M | 0.05% | −41,620−33.2% | Reduced |
| BNP Paribas Arbitrage, SA | 80,933 | $1.98M | 0.01% | +60,347+293.1% | Added |
| Prosight Management, LP | 80,000 | $1.96M | 1.08% | +80,000 | New |
| EAM Global Investors LLC | 78,976 | $1.94M | 0.51% | +78,976 | New |
| UBS Oconnor LLC | 72,375 | $1.77M | 0.02% | +72,375 | New |
| Ghost Tree Capital, LLC | 65,000 | $1.59M | 0.65% | +65,000 | New |
| Voya Investment Management LLC | 63,595 | $1.56M | 0.00% | +63,595 | New |
| Squarepoint Ops LLC | 57,994 | $1.42M | 0.01% | +13,830+31.3% | Added |
| Citadel Advisors LLC | 55,835 | $1.37M | 0.00% | −112,223−66.8% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 51,802 | $1.27M | 0.08% | −717−1.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 48,903 | $1.20M | 0.01% | +48,903 | New |
| Nuveen Asset Management, LLC | 40,290 | $987.0K | 0.00% | −915−2.2% | Reduced |
| Bank of New York Mellon Corp | 39,908 | $978.0K | 0.00% | +18,413+85.7% | Added |
| Stratos Wealth Partners, LTD. | 38,615 | $946.0K | 0.03% | +38,615 | New |
| State of Wisconsin Investment Board | 38,505 | $943.0K | 0.00% | −169,196−81.5% | Reduced |
| Candriam Luxembourg S.C.A. | 38,234 | $937.0K | 0.01% | +38,234 | New |
| Credit Suisse AG | 35,484 | $869.0K | 0.00% | +10,962+44.7% | Added |
| California State Teachers Retirement System | 32,520 | $797.0K | 0.00% | +574+1.8% | Added |
| Fiduciary Trust Co | 30,000 | $735.0K | 0.02% | +10,000+50.0% | Added |
| UBS Asset Management Americas Inc | 29,937 | $733.5K | 0.00% | −24,886−45.4% | Reduced |
| DekaBank Deutsche Girozentrale | 30,000 | $711.0K | 0.00% | +30,000 | New |
| Driehaus Capital Management LLC | 22,993 | $563.0K | 0.01% | +22,993 | New |
| Raymond James & Associates | 22,600 | $554.0K | 0.00% | +22,600 | New |
| Fred Alger Management, LLC | 20,286 | $497.0K | 0.00% | +20,286 | New |
| Stifel Financial Corp | 19,580 | $480.0K | 0.00% | +619+3.3% | Added |
| SEI Investments Co | 19,258 | $472.0K | 0.00% | +19,258 | New |
| Ameriprise Financial Inc | 18,140 | $445.0K | 0.00% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 18,035 | $442.0K | 0.04% | +18,035 | New |
| ClariVest Asset Management LLC | 16,800 | $412.0K | 0.02% | +16,800 | New |
| Price T Rowe Associates Inc | 16,300 | $400.0K | 0.00% | +16,300 | New |
| LMR Partners LLP | 15,713 | $385.0K | 0.01% | 00.0% | Unchanged |
| Harvest Investment Services, LLC | 13,941 | $341.0K | 0.42% | +13,941 | New |
| UBS Group AG | 12,635 | $309.0K | 0.00% | +5,128+68.3% | Added |
| Teacher Retirement System of Texas | 12,369 | $303.0K | 0.00% | +12,369 | New |
| Allianz Asset Management GmbH | 11,900 | $292.0K | 0.00% | +11,900 | New |
| Ensign Peak Advisors, Inc | 11,170 | $274.0K | 0.00% | −18,175−61.9% | Reduced |
| Arizona State Retirement System | 10,271 | $252.0K | 0.00% | +41+0.4% | Added |
| Legal & General Group Plc | 9,768 | $239.0K | 0.00% | −2,479−20.2% | Reduced |
| Gsa Capital Partners LLP | 9,092 | $223.0K | 0.03% | −14,055−60.7% | Reduced |
| Tower Research Capital LLC (TRC) | 8,474 | $207.0K | 0.00% | +2,670+46.0% | Added |
| Macquarie Group Ltd | 5,992 | $200.0K | 0.00% | −2,163−26.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 6,188 | $152.0K | 0.00% | +2,446+65.4% | Added |
| Sierra Capital LLC | 2,400 | $59.0K | 0.01% | 00.0% | Unchanged |
| Great West Life Assurance Co | 2,363 | $58.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 2,174 | $54.0K | 0.00% | −6,754−75.6% | Reduced |
| JPMorgan Chase & Co | 2,211 | $54.0K | 0.00% | +1,770+401.4% | Added |
| Focused Wealth Management, Inc | 2,000 | $49.0K | 0.01% | +2,000 | New |
| Denali Advisors LLC | 1,900 | $47.0K | 0.02% | +1,900 | New |
| New York State Common Retirement Fund | 1,072 | $26.0K | 0.00% | +758+241.4% | Added |
| Cutler Group LP | 1,000 | $24.0K | 0.00% | −336−25.1% | Reduced |
| IFP Advisors, Inc | 600 | $20.0K | 0.00% | +600 | New |
| Bank of Montreal | 567 | $14.0K | 0.00% | +567 | New |
| China Universal Asset Management Co., Ltd. | 475 | $12.0K | 0.01% | +475 | New |
| The PNC Financial Services Group, Inc. | 350 | $9.00K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 200 | $5.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 209 | $5.00K | 0.00% | −1−0.5% | Reduced |
| Signaturefd, LLC | 204 | $5.00K | 0.00% | +204 | New |
| Daiwa Securities Group Inc. | 172 | $4.00K | 0.00% | 00.0% | Unchanged |
| Hantz Financial Services, Inc. | 115 | $3.00K | 0.00% | −22,171−99.5% | Reduced |
| Newbridge Financial Services Group, Inc. | 65 | $2.00K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 65 | $2.00K | 0.00% | +65 | New |
| Beaird Harris Wealth Management, LLC | 49 | $1.00K | 0.00% | 00.0% | Unchanged |