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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

Q2 2026 vs. Q1 2026

How the institutions holding Rhythm Pharmaceuticals, Inc. changed between Q1 2026 and Q2 2026.

All holders in Q2 2026All holders in Q1 2026

13F holders of RYTM: Q1 2026 compared with Q2 2026
MeasureQ1 2026Of which not filed for Q2 2026Q2 2026Change
Holders2853305+23
Shares73.6M923.8K77.2M+4.58M (+6.3%)
Value$6.42B$80.4M$8.55B+$2.21B (+34.8%)

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (64)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q2 2026 but not at the end of Q1 2026.

Institutions new to RYTM in Q2 2026
InstitutionSharesValue% of portfolio
Jupiter Topco LLC925,490$102.8M0.04%
Norges Bank685,844$76.1M0.01%
Duquesne Family Office LLCSuperinvestorDuquesne Family Office203,618$22.6M0.52%
Assenagon Asset Management S.A.186,491$20.7M0.03%
First Turn Management, LLC154,018$17.1M1.83%
Nicholas Investment Partners, LP139,270$15.5M0.87%
Segall Bryant & Hamill, LLC121,866$13.5M0.16%
Longaeva Partners L.P.110,074$12.2M0.35%
Sphera Funds Management Ltd.80,400$8.93M1.28%
Capital Fund Management S.A.68,548$7.61M0.05%
Trexquant Investment LP56,248$6.25M0.04%
Canada Pension Plan Investment Board47,400$5.26M0.00%
Cinctive Capital Management LP42,739$4.75M0.19%
Zweig-DiMenna Associates LLC42,100$4.67M0.42%
Schonfeld Strategic Advisors LLC28,607$3.18M0.02%
Legato Capital Management LLC19,024$2.11M0.18%
Natixis Advisors, L.P.14,483$1.61M0.00%
Susquehanna Portfolio Strategies, LLC11,073$1.23M0.02%
Mackenzie Financial Corp10,936$1.21M0.00%
Y-Intercept (Hong Kong) Ltd7,925$879.9K0.02%
Pathstone Holdings, LLC6,911$767.3K0.00%
State of Wyoming6,354$705.5K0.07%
Walleye Capital LLC5,996$665.7K0.00%
Teachers Retirement System of the State of Kentucky5,601$622.0K0.00%
Fulcrum Asset Management LLP5,049$555.6K0.06%
Allstate Corp4,925$546.8K0.01%
O'Shaughnessy Asset Management, LLC4,122$457.7K0.00%
Matisse Capital4,000$444.1K0.18%
Magnetar Financial LLC3,908$433.9K0.00%
Mitsubishi UFJ Trust & Banking Corp3,860$428.6K0.00%
Envestnet Asset Management Inc3,769$418.5K0.00%
Virginia Retirement Systems Et Al3,700$410.8K0.00%
Sound View Wealth Advisors Group, LLC3,682$408.8K0.03%
Simplex Trading, LLC3,435$381.4K0.01%
CWM Advisors, LLC3,417$379.4K0.02%
Yorktown Management & Research Co Inc3,300$366.4K0.22%
Capstone Investment Advisors, LLC3,005$333.6K0.00%
Group One Trading, L.P.2,981$331.0K0.01%
Jane Street Group, LLC2,710$300.9K0.00%
Nykredit A/S2,525$280.4K0.00%
M&T Bank Corp2,178$241.8K0.00%
Cetera Investment Advisers2,098$232.9K0.00%
Everence Capital Management Inc2,053$228.0K0.01%
PSP Research LLC2,000$222.1K0.12%
nVerses Capital, LLC1,908$211.8K0.33%
Wealth Enhancement Advisory Services, LLC1,885$204.3K0.00%
Clear Street Markets LLC543$60.3K0.01%
Pacer Advisors, Inc.538$60.0K0.00%
Bayforest Capital Ltd511$56.7K0.05%
Global Retirement Partners, LLC460$51.1K0.00%
Accent Capital Management, LLC107$11.9K0.01%
SMA Capital LLC92$10.2K0.00%
Zions Bancorporation, National Association56$6.22K0.00%
Hurley Capital, LLC56$6.22K0.00%
Quarry LP29$3.22K0.00%
SJS Investment Consulting Inc.20$2.22K0.00%
Clearstead Advisors, LLC7$7790.00%
Hughes Financial Services, LLC6$6660.00%
Montag A & Associates Inc5$5640.00%
Ares Financial Consulting, LLC5$5550.00%
Silver Grove Financial Group, Inc.5$5550.00%
Downshift Financial, LLC2$2220.00%
Massmutual Trust Co FSB1$1110.00%
Principia Wealth Advisory, LLC1$1110.00%

Sold out (41)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q1 2026 and filed for Q2 2026 without it.

Institutions that sold out of RYTM in Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Lord, Abbett & Co. LLC348,953$30.3M
Hood River Capital Management LLC239,912$20.9M
M&G Plc138,567$12.1M
Balyasny Asset Management LLC52,967$4.61M
Castleark Management LLC52,279$4.55M
Harvest Investment Services, LLC48,468$4.22M
Utah Retirement Systems42,177$3.67M
Alyeska Investment Group, L.P.32,589$2.83M
Harbor Capital Advisors, Inc.30,353$2.64M
PDT Partners, LLC27,232$2.37M
HSBC Holdings PLC14,307$1.22M
Hudson Bay Capital Management LP9,120$793.2K
HighTower Advisors, LLC9,058$787.8K
Prelude Capital Management, LLC8,372$728.1K
IMC-Chicago, LLC6,697$582.4K
Texas Treasury Safekeeping Trust Co6,154$535.0K
Campbell & CO Investment Adviser LLC5,958$518.2K
Blueshift Asset Management, LLC5,787$503.3K
Centiva Capital, LP4,000$347.9K
Fox Run Management, L.L.C.4,499$347.5K
Bank of Montreal3,801$330.6K
Brevan Howard Capital Management LP3,777$328.5K
Chicago Partners Investment Group LLC3,125$266.2K
Ethic Inc.3,003$261.2K
MAI Capital Management2,710$235.7K
Blackstone Group Inc.2,600$226.1K
DRW Securities, LLC2,562$222.8K
Two Sigma Securities, LLC2,545$221.3K
Cornerstone Partners Capital Management, LLC2,462$214.1K
Verdad Advisers, LP2,445$212.6K
Quantbot Technologies LP1,363$118.5K
Sound Income Strategies, LLC114$10.0K
Eastern Bank59$5.13K
Advisory Services Network, LLC37$3.22K
Golden State Equity Partners37$3.22K
Root Financial Partners, LLC31$2.70K
JFS Wealth Advisors, LLC10$870
Toronto Dominion Bank6$522
Twin Peaks Wealth Advisors, LLC6$522
HFM Investment Advisors, LLC1$87
Bay Harbor Wealth Management, LLC1$86

Not filed for Q2 2026 yet (3)

Institutions that held Rhythm Pharmaceuticals, Inc. at the end of Q1 2026 and haven't filed a 13F for Q2 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding RYTM in Q1 2026 that haven't filed for Q2 2026
InstitutionShares, Q1 2026Value, Q1 2026
Janus Henderson Group PLC918,153$79.9M
Leo Wealth, LLC3,088$268.6K
CWM, LLC2,536$220.6K