Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 304
- +23 vs. Q1 2026
- Shares held
- 77.2M
- +4.58M (+6.3%) vs. Q1 2026
- Total value
- $8.55B
- +$2.21B (+34.8%) vs. Q1 2026
- New holders
- 64
- 105 more added
- Sold out
- 41
- 101 more reduced
4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Asset Management, Ltd | 53,279 | $5.92M | 0.00% | +3,590+7.2% | Added |
| Man Group plc | 50,788 | $5.64M | 0.01% | +46,766+1,162.8% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $5.45M | 4.15% | 00.0% | Unchanged |
| Canada Pension Plan Investment Board | 47,400 | $5.26M | 0.00% | +47,400 | New |
| Hillsdale Investment Management Inc. | 44,000 | $4.89M | 0.11% | +3,700+9.2% | Added |
| Legal & General Group Plc | 43,908 | $4.88M | 0.00% | −3,124−6.6% | Reduced |
| Cinctive Capital Management LP | 42,739 | $4.75M | 0.19% | +42,739 | New |
| Zweig-DiMenna Associates LLC | 42,100 | $4.67M | 0.42% | +42,100 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 41,929 | $4.66M | 0.00% | −1,943−4.4% | Reduced |
| TD Asset Management Inc | 38,778 | $4.31M | 0.00% | 00.0% | Unchanged |
| EFG International AG | 33,577 | $3.73M | 0.07% | −637−1.9% | Reduced |
| First Trust Advisors LP | 32,482 | $3.61M | 0.00% | −53,024−62.0% | Reduced |
| Exome Asset Management LLC | 32,209 | $3.58M | 2.21% | −8,372−20.6% | Reduced |
| Rafferty Asset Management, LLC | 32,207 | $3.58M | 0.01% | −17,898−35.7% | Reduced |
| State of Wisconsin Investment Board | 32,189 | $3.57M | 0.01% | −4,382−12.0% | Reduced |
| MetLife Investment Management | 32,104 | $3.56M | 0.02% | +3,215+11.1% | Added |
| D. E. Shaw & Co., Inc. | 30,168 | $3.35M | 0.00% | −2,484−7.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 29,159 | $3.23M | 0.00% | −5,518−15.9% | Reduced |
| Schonfeld Strategic Advisors LLC | 28,607 | $3.18M | 0.02% | +28,607 | New |
| Aspiriant, LLC | 27,960 | $3.10M | 0.08% | −5,047−15.3% | Reduced |
| Mutual of America Capital Management LLC | 27,861 | $3.09M | 0.03% | +5,332+23.7% | Added |
| Creative Planning | 25,835 | $2.87M | 0.00% | +4,750+22.5% | Added |
| Vanguard Global Advisers, LLC | 23,654 | $2.63M | 0.00% | −6,046−20.4% | Reduced |
| Wedge Capital Management L L P | 23,422 | $2.60M | 0.04% | −1,113−4.5% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,109 | $2.57M | 0.00% | +7,511+48.2% | Added |
| SEI Investments Co | 22,087 | $2.45M | 0.00% | −18,598−45.7% | Reduced |
| Advisors Asset Management, Inc. | 21,896 | $2.43M | 0.04% | +3,178+17.0% | Added |
| SG Americas Securities, LLC | 21,333 | $2.37M | 0.00% | +2,573+13.7% | Added |
| Captrust Financial Advisors | 19,945 | $2.21M | 0.00% | +1,798+9.9% | Added |
| Aquatic Capital Management LLC | 19,754 | $2.19M | 0.08% | −9,917−33.4% | Reduced |
| Legato Capital Management LLC | 19,024 | $2.11M | 0.18% | +19,024 | New |
| Dimensional Fund Advisors LP | 18,973 | $2.11M | 0.00% | −178−0.9% | Reduced |
| Handelsbanken Fonder AB | 18,921 | $2.10M | 0.01% | +1,400+8.0% | Added |
| Lazard Asset Management LLC | 18,319 | $2.03M | 0.00% | −14,569−44.3% | Reduced |
| Knights of Columbus Asset Advisors LLC | 18,043 | $2.00M | 0.10% | +2,454+15.7% | Added |
| State of New Jersey Common Pension Fund D | 17,664 | $1.96M | 0.01% | −1,722−8.9% | Reduced |
| Profund Advisors LLC | 16,805 | $1.87M | 0.05% | −5,982−26.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 16,280 | $1.81M | 0.01% | +1,686+11.6% | Added |
| Los Angeles Capital Management LLC | 15,641 | $1.74M | 0.01% | +6,422+69.7% | Added |
| State Board of Administration of Florida Retirement System | 15,342 | $1.70M | 0.00% | +692+4.7% | Added |
| Arizona State Retirement System | 15,073 | $1.67M | 0.01% | −508−3.3% | Reduced |
| Vanguard Investments Australia, Ltd. | 14,666 | $1.63M | 0.00% | +739+5.3% | Added |
| Natixis Advisors, L.P. | 14,483 | $1.61M | 0.00% | +14,483 | New |
| Tudor Investment Corp Et Al | 13,886 | $1.54M | 0.01% | −5,760−29.3% | Reduced |
| Jasper Ridge Partners, L.P. | 13,845 | $1.54M | 0.03% | 00.0% | Unchanged |
| HighVista Strategies LLC | 13,657 | $1.52M | 0.35% | −3,139−18.7% | Reduced |
| Barclays PLC | 13,209 | $1.47M | 0.00% | +2,557+24.0% | Added |
| Virtus Investment Advisers, Inc. | 13,158 | $1.46M | 0.34% | +5,724+77.0% | Added |
| Stifel Financial Corp | 12,689 | $1.41M | 0.00% | +350+2.8% | Added |
| KLP Kapitalforvaltning AS | 12,500 | $1.39M | 0.00% | 00.0% | Unchanged |
| Entropy Technologies, LP | 12,077 | $1.34M | 0.05% | +1,759+17.0% | Added |
| Jones Financial Companies LLLP | 12,066 | $1.33M | 0.00% | +7,148+145.3% | Added |
| Intech Investment Management LLC | 11,664 | $1.30M | 0.01% | −2,075−15.1% | Reduced |
| DnB Asset Management AS | 11,465 | $1.27M | 0.00% | +270+2.4% | Added |
| Bridgefront Capital, LLC | 11,282 | $1.25M | 0.33% | −1,213−9.7% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 11,073 | $1.23M | 0.02% | +11,073 | New |
| Guggenheim Capital LLC | 10,984 | $1.22M | 0.01% | −5,570−33.6% | Reduced |
| Mackenzie Financial Corp | 10,936 | $1.21M | 0.00% | +10,936 | New |
| China Universal Asset Management Co., Ltd. | 10,917 | $1.21M | 0.07% | −1,201−9.9% | Reduced |
| Cannon Financial Strategists, Inc. | 10,000 | $1.11M | 0.13% | 00.0% | Unchanged |
| ProShare Advisors LLC | 9,476 | $1.05M | 0.00% | −1,244−11.6% | Reduced |
| AlphaCentric Advisors LLC | 9,449 | $1.05M | 0.89% | +152+1.6% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 9,393 | $1.04M | 0.00% | −53,543−85.1% | Reduced |
| Inceptionr LLC | 9,353 | $1.04M | 0.26% | +4,974+113.6% | Added |
| Marshall Wace, LLP | 8,174 | $907.6K | 0.00% | −1,454−15.1% | Reduced |
| Exchange Traded Concepts, LLC | 7,966 | $884.5K | 0.00% | −497−5.9% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 7,925 | $879.9K | 0.02% | +7,925 | New |
| Toth Financial Advisory Corp | 7,800 | $866.0K | 0.08% | −2,200−22.0% | Reduced |
| Victory Capital Management Inc | 7,679 | $852.6K | 0.00% | −12,825−62.5% | Reduced |
| The PNC Financial Services Group, Inc. | 7,657 | $850.2K | 0.00% | +719+10.4% | Added |
| Pathstone Holdings, LLC | 6,911 | $767.3K | 0.00% | +6,911 | New |
| Teacher Retirement System of Texas | 6,370 | $707.3K | 0.00% | −960−13.1% | Reduced |
| State of Wyoming | 6,354 | $705.5K | 0.07% | +6,354 | New |
| LPL Financial LLC | 6,284 | $697.7K | 0.00% | +86+1.4% | Added |
| STRS Ohio | 6,000 | $666.2K | 0.00% | −22,914−79.2% | Reduced |
| Walleye Capital LLC | 5,996 | $665.7K | 0.00% | +5,996 | New |
| Rockefeller Capital Management L.P. | 5,945 | $660.1K | 0.00% | +1,101+22.7% | Added |
| Great West Life Assurance Co | 5,797 | $642.0K | 0.00% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 5,601 | $622.0K | 0.00% | +5,601 | New |
| E. Ohman J:or Asset Management AB | 5,523 | $613.2K | 0.01% | +1,114+25.3% | Added |
| Gotham Asset Management, LLC | 5,516 | $612.4K | 0.00% | +668+13.8% | Added |
| Public Employees Retirement Association of Colorado | 5,463 | $607.0K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 5,465 | $606.8K | 0.00% | +475+9.5% | Added |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 5,440 | $604.0K | 0.02% | +790+17.0% | Added |
| Ameritas Investment Partners, Inc. | 5,010 | $556.3K | 0.01% | +645+14.8% | Added |
| Fulcrum Asset Management LLP | 5,049 | $555.6K | 0.06% | +5,049 | New |
| Allstate Corp | 4,925 | $546.8K | 0.01% | +4,925 | New |
| E Fund Management Co., Ltd. | 4,751 | $527.5K | 0.01% | −1,702−26.4% | Reduced |
| Two Sigma Investments, LP | 4,600 | $510.7K | 0.00% | +300+7.0% | Added |
| Susquehanna International Group, LLP | 4,372 | $485.4K | 0.00% | −46,412−91.4% | Reduced |
| Fifth Third Bancorp | 4,290 | $476.4K | 0.00% | −970−18.4% | Reduced |
| Abel Hall, LLC | 4,258 | $472.8K | 0.08% | +243+6.1% | Added |
| Principal Financial Group Inc | 4,220 | $468.5K | 0.00% | −1,417−25.1% | Reduced |
| O'Shaughnessy Asset Management, LLC | 4,122 | $457.7K | 0.00% | +4,122 | New |
| JustInvest LLC | 4,054 | $450.1K | 0.00% | +952+30.7% | Added |
| Matisse Capital | 4,000 | $444.1K | 0.18% | +4,000 | New |
| Magnetar Financial LLC | 3,908 | $433.9K | 0.00% | +3,908 | New |
| Mitsubishi UFJ Trust & Banking Corp | 3,860 | $428.6K | 0.00% | +3,860 | New |
| Quantinno Capital Management LP | 3,838 | $426.1K | 0.00% | −13−0.3% | Reduced |
| Envestnet Asset Management Inc | 3,769 | $418.5K | 0.00% | +3,769 | New |