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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
304
+23 vs. Q1 2026
Shares held
77.2M
+4.58M (+6.3%) vs. Q1 2026
Total value
$8.55B
+$2.21B (+34.8%) vs. Q1 2026
New holders
64
105 more added
Sold out
41
101 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 304 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ2 2026: $8.55B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q1 2026.

Institutions holding RYTM in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Ensign Peak Advisors, Inc3,709$411.8K0.00%−150−3.9%Reduced
Freestone Capital Holdings, LLC3,700$410.8K0.01%00.0%Unchanged
Virginia Retirement Systems Et Al3,700$410.8K0.00%+3,700New
Sound View Wealth Advisors Group, LLC3,682$408.8K0.03%+3,682New
Swiss Life Asset Management Ltd3,539$392.9K0.00%+198+5.9%Added
Simplex Trading, LLC3,435$381.4K0.01%+3,435New
Amundi3,422$379.9K0.00%−595−14.8%Reduced
CWM Advisors, LLC3,417$379.4K0.02%+3,417New
Yorktown Management & Research Co Inc3,300$366.4K0.22%+3,300New
Cerity Partners LLC3,137$348.3K0.00%−78−2.4%Reduced
Mirae Asset Global Investments Co., Ltd.3,068$340.6K0.00%−494−13.9%Reduced
CIBC Bancorp USA Inc.3,048$338.4K0.00%+385+14.5%Added
Capstone Investment Advisors, LLC3,005$333.6K0.00%+3,005New
Allianz Asset Management GmbH3,000$333.1K0.00%00.0%Unchanged
Group One Trading, L.P.2,981$331.0K0.01%+2,981New
Jane Street Group, LLC2,710$300.9K0.00%+2,710New
Nykredit A/S2,525$280.4K0.00%+2,525New
Integrated Wealth Concepts LLC2,481$275.5K0.00%+10.0%Added
Centaurus Financial, Inc.2,454$272.0K0.01%+140+6.1%Added
M&T Bank Corp2,178$241.8K0.00%+2,178New
CIBC Asset Management Inc2,112$234.5K0.00%−736−25.8%Reduced
Cetera Investment Advisers2,098$232.9K0.00%+2,098New
Tower Research Capital LLC (TRC)2,067$229.5K0.01%−5,648−73.2%Reduced
Everence Capital Management Inc2,053$228.0K0.01%+2,053New
Marex Group plc2,000$222.1K0.00%−1,288−39.2%Reduced
PSP Research LLC2,000$222.1K0.12%+2,000New
XTX Topco Ltd1,996$221.6K0.00%−57,506−96.6%Reduced
CenterBook Partners LP1,975$219.3K0.01%−7,051−78.1%Reduced
ZRC Wealth Management, LLC1,971$218.8K0.07%00.0%Unchanged
nVerses Capital, LLC1,908$211.8K0.33%+1,908New
Wealth Enhancement Advisory Services, LLC1,885$204.3K0.00%+1,885New
Whittier Trust Co1,760$196.6K0.00%−51−2.8%Reduced
KBC Group NV1,707$190.0K0.00%00.0%Unchanged
Royal Bank of Canada1,661$184.0K0.00%+1,599+2,579.0%Added
Nisa Investment Advisors, LLC1,494$165.9K0.00%+356+31.3%Added
GF Fund Management Co. Ltd.1,448$160.8K0.00%−50−3.3%Reduced
Northwest & Ethical Investments L.P.1,100$121.0K0.00%−1,391−55.8%Reduced
US Bancorp1,020$113.3K0.00%−21−2.0%Reduced
Bellevue Group AG1,016$112.8K0.00%00.0%Unchanged
Mitsubishi UFJ Asset Management (UK) Ltd.1,000$111.0K0.05%00.0%Unchanged
Advisor Group Holdings, Inc.982$109.0K0.00%+43+4.6%Added
Liberty Mutual Group Asset Management Inc.880$97.7K0.01%−19,634−95.7%Reduced
SRS Capital Advisors, Inc.814$90.4K0.00%+446+121.2%Added
Farther Finance Advisors, LLC653$72.5K0.00%+8+1.2%Added
Kemnay Advisory Services Inc.616$68.4K0.01%+54+9.6%Added
Acadian Asset Management LLC609$67.0K0.00%−1,609−72.5%Reduced
Clear Street Markets LLC543$60.3K0.01%+543New
Pacer Advisors, Inc.538$60.0K0.00%+538New
Bayforest Capital Ltd511$56.7K0.05%+511New
Global Retirement Partners, LLC460$51.1K0.00%+460New
GAMMA Investing LLC364$40.4K0.00%+97+36.3%Added
Smartleaf Asset Management LLC264$29.1K0.00%00.0%Unchanged
Signaturefd, LLC231$25.6K0.00%+7+3.1%Added
Optiver Holding B.V.220$24.4K0.00%+170+340.0%Added
SBI Securities Co., Ltd.217$24.1K0.00%−85−28.1%Reduced
E Fund Management (Hong Kong) Co., Ltd.209$23.2K0.01%+55+35.7%Added
Sterling Capital Management LLC194$21.5K0.00%−149−43.4%Reduced
Covestor Ltd179$20.0K0.01%−66−26.9%Reduced
True Wealth Design, LLC147$16.3K0.00%00.0%Unchanged
Truvestments Capital LLC138$15.3K0.00%00.0%Unchanged
Allworth Financial LP137$15.2K0.00%+54+65.1%Added
Rothschild Investment LLC109$12.1K0.00%+23+26.7%Added
Larson Financial Group LLC107$11.9K0.00%+55+105.8%Added
Accent Capital Management, LLC107$11.9K0.01%+107New
Danske Bank A/S100$11.1K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC94$10.4K0.00%−20−17.5%Reduced
Cassaday & Co Wealth Management LLC93$10.3K0.00%00.0%Unchanged
SMA Capital LLC92$10.2K0.00%+92New
Essential Partners LLC77$8.55K0.00%−43−35.8%Reduced
EverSource Wealth Advisors, LLC70$7.77K0.00%−479−87.2%Reduced
Pinnacle Wealth Planning Services, Inc.67$7.44K0.00%+65+3,250.0%Added
Harbour Investments, Inc.60$6.66K0.00%00.0%Unchanged
WPG Advisers, LLC58$6.44K0.00%−2−3.3%Reduced
Zions Bancorporation, National Association56$6.22K0.00%+56New
Hurley Capital, LLC56$6.22K0.00%+56New
First Horizon Corp53$5.88K0.00%+18+51.4%Added
Cedar Mountain Advisors, LLC51$5.66K0.00%00.0%Unchanged
Versant Capital Management, Inc36$4.00K0.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.35$3.89K0.00%+24+218.2%Added
Parkside Financial Bank & Trust33$3.66K0.00%00.0%Unchanged
Quarry LP29$3.22K0.00%+29New
Bessemer Group Inc30$3.00K0.00%00.0%Unchanged
IFP Advisors, Inc27$3.00K0.00%−19−41.3%Reduced
Parallel Advisors, LLC21$2.33K0.00%−4−16.0%Reduced
Fortitude Family Office, LLC21$2.33K0.00%+12+133.3%Added
SJS Investment Consulting Inc.20$2.22K0.00%+20New
UMA Financial Services, Inc.16$1.78K0.00%00.0%Unchanged
CVA Family Office, LLC12$1.33K0.00%−16−57.1%Reduced
Whipplewood Advisors, LLC11$1.22K0.00%00.0%Unchanged
Dogwood Wealth Management LLC11$1.22K0.00%00.0%Unchanged
Bare Financial Services, Inc8$8880.00%−5−38.5%Reduced
Clearstead Advisors, LLC7$7790.00%+7New
LRI Investments, LLC6$6660.00%00.0%Unchanged
Hughes Financial Services, LLC6$6660.00%+6New
Montag A & Associates Inc5$5640.00%+5New
Huntington National Bank5$5550.00%00.0%Unchanged
Ares Financial Consulting, LLC5$5550.00%+5New
Silver Grove Financial Group, Inc.5$5550.00%+5New
GHP Investment Advisors, Inc.3$3340.00%00.0%Unchanged
Godfrey Financial Associates, Inc.3$3330.00%00.0%Unchanged