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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 305 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
285
+10 vs. Q4 2025
Shares held
73.6M
+6.99M (+10.5%) vs. Q4 2025
Total value
$6.42B
−$704.3M (−9.9%) vs. Q4 2025
New holders
63
102 more added
Sold out
53
89 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 285 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 305 institutions
Value heldQ1 2026: $6.42B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026305$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding RYTM in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Marex Group plc3,288$286.0K0.00%+3,288New
Cerity Partners LLC3,215$279.6K0.00%−449−12.3%Reduced
JustInvest LLC3,102$269.8K0.00%+723+30.4%Added
Leo Wealth, LLC3,088$268.6K0.02%−3,864−55.6%Reduced
Chicago Partners Investment Group LLC3,125$266.2K0.01%+386+14.1%Added
Ethic Inc.3,003$261.2K0.00%+3,003New
Allianz Asset Management GmbH3,000$260.9K0.00%−5,000−62.5%Reduced
Cim Investment Mangement Inc2,993$260.3K0.07%00.0%Unchanged
CIBC Asset Management Inc2,848$247.7K0.00%00.0%Unchanged
MAI Capital Management2,710$235.7K0.00%+2,708+135,400.0%Added
CIBC Bancorp USA Inc.2,663$231.6K0.00%+2,663New
Blackstone Group Inc.2,600$226.1K0.00%+2,600New
DRW Securities, LLC2,562$222.8K0.01%+2,562New
Two Sigma Securities, LLC2,545$221.3K0.03%−2,398−48.5%Reduced
CWM, LLC2,536$220.6K0.00%−231−8.3%Reduced
Northwest & Ethical Investments L.P.2,491$216.6K0.01%+2,491New
Integrated Wealth Concepts LLC2,480$215.7K0.00%+2,480New
Cornerstone Partners Capital Management, LLC2,462$214.1K0.53%+2,462New
Verdad Advisers, LP2,445$212.6K0.24%+2,445New
Centaurus Financial, Inc.2,314$201.0K0.01%−75−3.1%Reduced
Acadian Asset Management LLC2,218$192.0K0.00%−3,887−63.7%Reduced
ZRC Wealth Management, LLC1,971$171.4K0.06%00.0%Unchanged
Whittier Trust Co1,811$157.5K0.00%00.0%Unchanged
KBC Group NV1,707$148.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,498$130.3K0.00%+188+14.4%Added
Quantbot Technologies LP1,363$118.5K0.00%+1,363New
Nisa Investment Advisors, LLC1,138$99.0K0.00%−12,001−91.3%Reduced
US Bancorp1,041$90.5K0.00%+88+9.2%Added
Bellevue Group AG1,016$88.4K0.00%−6,488−86.5%Reduced
Mitsubishi UFJ Asset Management (UK) Ltd.1,000$87.0K0.04%+1,000New
Advisor Group Holdings, Inc.939$81.7K0.00%−100−9.6%Reduced
Farther Finance Advisors, LLC645$56.8K0.00%+3+0.5%Added
Kemnay Advisory Services Inc.562$48.9K0.01%+355+171.5%Added
EverSource Wealth Advisors, LLC549$47.7K0.00%+283+106.4%Added
SRS Capital Advisors, Inc.368$32.1K0.00%−13−3.4%Reduced
Sterling Capital Management LLC343$29.8K0.00%−1−0.3%Reduced
SBI Securities Co., Ltd.302$26.3K0.00%−41−12.0%Reduced
GAMMA Investing LLC267$23.2K0.00%−94−26.0%Reduced
Covestor Ltd245$21.0K0.01%−334−57.7%Reduced
Smartleaf Asset Management LLC264$20.4K0.00%−135−33.8%Reduced
Signaturefd, LLC224$19.5K0.00%−8−3.4%Reduced
E Fund Management (Hong Kong) Co., Ltd.154$13.4K0.01%+154New
True Wealth Design, LLC147$12.8K0.00%00.0%Unchanged
Truvestments Capital LLC138$12.0K0.00%00.0%Unchanged
Essential Partners LLC120$10.4K0.00%−103−46.2%Reduced
Sound Income Strategies, LLC114$10.0K0.00%+114New
Basecamp Wealth Advisors LLC114$9.91K0.00%−11−8.8%Reduced
Danske Bank A/S100$8.70K0.00%−1,000−90.9%Reduced
Cassaday & Co Wealth Management LLC93$8.09K0.00%+93New
Rothschild Investment LLC86$7.48K0.00%−5−5.5%Reduced
Allworth Financial LP83$7.22K0.00%−26−23.9%Reduced
Harbour Investments, Inc.60$5.22K0.00%00.0%Unchanged
WPG Advisers, LLC60$5.22K0.00%00.0%Unchanged
Eastern Bank59$5.13K0.00%00.0%Unchanged
Royal Bank of Canada62$5.00K0.00%−1,614−96.3%Reduced
Larson Financial Group LLC52$4.52K0.00%−25−32.5%Reduced
Cedar Mountain Advisors, LLC51$4.43K0.00%+51New
Optiver Holding B.V.50$4.35K0.00%−42−45.7%Reduced
IFP Advisors, Inc46$4.00K0.00%+10+27.8%Added
Advisory Services Network, LLC37$3.22K0.00%+37New
Golden State Equity Partners37$3.22K0.00%+37New
Versant Capital Management, Inc36$3.13K0.00%00.0%Unchanged
First Horizon Corp35$3.04K0.00%+5+16.7%Added
Bessemer Group Inc30$3.00K0.00%−36−54.5%Reduced
Parkside Financial Bank & Trust33$2.87K0.00%00.0%Unchanged
Root Financial Partners, LLC31$2.70K0.00%−12−27.9%Reduced
CVA Family Office, LLC28$2.44K0.00%+16+133.3%Added
Parallel Advisors, LLC25$2.17K0.00%00.0%Unchanged
UMA Financial Services, Inc.16$1.39K0.00%00.0%Unchanged
Bare Financial Services, Inc13$1.13K0.00%−9−40.9%Reduced
Keating Financial Advisory Services, Inc.11$9570.00%+2+22.2%Added
Whipplewood Advisors, LLC11$9570.00%+11New
Dogwood Wealth Management LLC11$9570.00%+11New
JFS Wealth Advisors, LLC10$8700.00%00.0%Unchanged
Fortitude Family Office, LLC9$7830.00%+3+50.0%Added
Toronto Dominion Bank6$5220.00%00.0%Unchanged
Twin Peaks Wealth Advisors, LLC6$5220.00%+6New
LRI Investments, LLC6$5220.00%+6New
Huntington National Bank5$4350.00%+5New
DiNuzzo Private Wealth, Inc.3$2610.00%00.0%Unchanged
GHP Investment Advisors, Inc.3$2610.00%+3New
Godfrey Financial Associates, Inc.3$2610.00%+3New
Pinnacle Wealth Planning Services, Inc.2$1740.00%+2New
HFM Investment Advisors, LLC1$870.00%−1−50.0%Reduced
Bay Harbor Wealth Management, LLC1$860.00%00.0%Unchanged
NEA Management Company, LLC0$00.00%−2,909,956−100.0%Sold out
Jennison Associates LLC0$00.00%−918,567−100.0%Sold out
First Turn Management, LLC0$00.00%−146,303−100.0%Sold out
Zweig-DiMenna Associates LLC0$00.00%−81,600−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−60,575−100.0%Sold out
StemPoint Capital LP0$00.00%−58,915−100.0%Sold out
EAM Investors, LLC0$00.00%−57,327−100.0%Sold out
Rhenman & Partners Asset Management AB0$00.00%−35,000−100.0%Sold out
Nicholas Investment Partners, LP0$00.00%−34,710−100.0%Sold out
Magnetar Financial LLC0$00.00%−29,598−100.0%Sold out
Penserra Capital Management LLC0$00.00%−21,514−100.0%Sold out
Hennion & Walsh Asset Management, Inc.0$00.00%−10,908−100.0%Sold out
Fred Alger Management, LLC0$00.00%−9,301−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−9,200−100.0%Sold out
Headlands Technologies LLC0$00.00%−8,632−100.0%Sold out