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Rhythm Pharmaceuticals, Inc.

RYTM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001649904

In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
285
+10 vs. Q4 2025
Shares held
73.6M
+6.99M (+10.5%) vs. Q4 2025
Total value
$6.42B
−$704.3M (−9.9%) vs. Q4 2025
New holders
63
102 more added
Sold out
53
89 more reduced

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 285 institutions
Q1 2021: 124 institutionsQ2 2021: 105 institutionsQ3 2021: 97 institutionsQ4 2021: 98 institutionsQ1 2022: 111 institutionsQ2 2022: 90 institutionsQ3 2022: 101 institutionsQ4 2022: 115 institutionsQ1 2023: 126 institutionsQ2 2023: 116 institutionsQ3 2023: 144 institutionsQ4 2023: 169 institutionsQ1 2024: 167 institutionsQ2 2024: 165 institutionsQ3 2024: 176 institutionsQ4 2024: 203 institutionsQ1 2025: 228 institutionsQ2 2025: 227 institutionsQ3 2025: 264 institutionsQ4 2025: 281 institutionsQ1 2026: 285 institutionsQ2 2026: 304 institutions
Value heldQ1 2026: $6.42B
Q1 2021: $1.01BQ2 2021: $905.6MQ3 2021: $626.3MQ4 2021: $483.6MQ1 2022: $562.7MQ2 2022: $190.8MQ3 2022: $1.45BQ4 2022: $1.81BQ1 2023: $1.08BQ2 2023: $1.09BQ3 2023: $1.56BQ4 2023: $3.07BQ1 2024: $2.95BQ2 2024: $2.85BQ3 2024: $3.55BQ4 2024: $3.63BQ1 2025: $3.44BQ2 2025: $4.20BQ3 2025: $7.20BQ4 2025: $7.80BQ1 2026: $6.42BQ2 2026: $8.55B
Institutions holding RYTM and their total value by quarter
QuarterHoldersValue
Q2 2026304$8.55B
Q1 2026285$6.42B
Q4 2025281$7.80B
Q3 2025264$7.20B
Q2 2025227$4.20B
Q1 2025228$3.44B
Q4 2024203$3.63B
Q3 2024176$3.55B
Q2 2024165$2.85B
Q1 2024167$2.95B
Q4 2023169$3.07B
Q3 2023144$1.56B
Q2 2023116$1.09B
Q1 2023126$1.08B
Q4 2022115$1.81B
Q3 2022101$1.45B
Q2 202290$190.8M
Q1 2022111$562.7M
Q4 202198$483.6M
Q3 202197$626.3M
Q2 2021105$905.6M
Q1 2021124$1.01B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding RYTM in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Bay Harbor Wealth Management, LLC1$860.00%00.0%Unchanged
HFM Investment Advisors, LLC1$870.00%−1−50.0%Reduced
Pinnacle Wealth Planning Services, Inc.2$1740.00%+2New
DiNuzzo Private Wealth, Inc.3$2610.00%00.0%Unchanged
GHP Investment Advisors, Inc.3$2610.00%+3New
Godfrey Financial Associates, Inc.3$2610.00%+3New
Huntington National Bank5$4350.00%+5New
Toronto Dominion Bank6$5220.00%00.0%Unchanged
Twin Peaks Wealth Advisors, LLC6$5220.00%+6New
LRI Investments, LLC6$5220.00%+6New
Fortitude Family Office, LLC9$7830.00%+3+50.0%Added
JFS Wealth Advisors, LLC10$8700.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.11$9570.00%+2+22.2%Added
Whipplewood Advisors, LLC11$9570.00%+11New
Dogwood Wealth Management LLC11$9570.00%+11New
Bare Financial Services, Inc13$1.13K0.00%−9−40.9%Reduced
UMA Financial Services, Inc.16$1.39K0.00%00.0%Unchanged
Parallel Advisors, LLC25$2.17K0.00%00.0%Unchanged
CVA Family Office, LLC28$2.44K0.00%+16+133.3%Added
Root Financial Partners, LLC31$2.70K0.00%−12−27.9%Reduced
Parkside Financial Bank & Trust33$2.87K0.00%00.0%Unchanged
Bessemer Group Inc30$3.00K0.00%−36−54.5%Reduced
First Horizon Corp35$3.04K0.00%+5+16.7%Added
Versant Capital Management, Inc36$3.13K0.00%00.0%Unchanged
Golden State Equity Partners37$3.22K0.00%+37New
Advisory Services Network, LLC37$3.22K0.00%+37New
IFP Advisors, Inc46$4.00K0.00%+10+27.8%Added
Optiver Holding B.V.50$4.35K0.00%−42−45.7%Reduced
Cedar Mountain Advisors, LLC51$4.43K0.00%+51New
Larson Financial Group LLC52$4.52K0.00%−25−32.5%Reduced
Royal Bank of Canada62$5.00K0.00%−1,614−96.3%Reduced
Eastern Bank59$5.13K0.00%00.0%Unchanged
Harbour Investments, Inc.60$5.22K0.00%00.0%Unchanged
WPG Advisers, LLC60$5.22K0.00%00.0%Unchanged
Allworth Financial LP83$7.22K0.00%−26−23.9%Reduced
Rothschild Investment LLC86$7.48K0.00%−5−5.5%Reduced
Cassaday & Co Wealth Management LLC93$8.09K0.00%+93New
Danske Bank A/S100$8.70K0.00%−1,000−90.9%Reduced
Basecamp Wealth Advisors LLC114$9.91K0.00%−11−8.8%Reduced
Sound Income Strategies, LLC114$10.0K0.00%+114New
Essential Partners LLC120$10.4K0.00%−103−46.2%Reduced
Truvestments Capital LLC138$12.0K0.00%00.0%Unchanged
True Wealth Design, LLC147$12.8K0.00%00.0%Unchanged
E Fund Management (Hong Kong) Co., Ltd.154$13.4K0.01%+154New
Signaturefd, LLC224$19.5K0.00%−8−3.4%Reduced
Smartleaf Asset Management LLC264$20.4K0.00%−135−33.8%Reduced
Covestor Ltd245$21.0K0.01%−334−57.7%Reduced
GAMMA Investing LLC267$23.2K0.00%−94−26.0%Reduced
SBI Securities Co., Ltd.302$26.3K0.00%−41−12.0%Reduced
Sterling Capital Management LLC343$29.8K0.00%−1−0.3%Reduced
SRS Capital Advisors, Inc.368$32.1K0.00%−13−3.4%Reduced
EverSource Wealth Advisors, LLC549$47.7K0.00%+283+106.4%Added
Kemnay Advisory Services Inc.562$48.9K0.01%+355+171.5%Added
Farther Finance Advisors, LLC645$56.8K0.00%+3+0.5%Added
Advisor Group Holdings, Inc.939$81.7K0.00%−100−9.6%Reduced
Mitsubishi UFJ Asset Management (UK) Ltd.1,000$87.0K0.04%+1,000New
Bellevue Group AG1,016$88.4K0.00%−6,488−86.5%Reduced
US Bancorp1,041$90.5K0.00%+88+9.2%Added
Nisa Investment Advisors, LLC1,138$99.0K0.00%−12,001−91.3%Reduced
Quantbot Technologies LP1,363$118.5K0.00%+1,363New
GF Fund Management Co. Ltd.1,498$130.3K0.00%+188+14.4%Added
KBC Group NV1,707$148.0K0.00%00.0%Unchanged
Whittier Trust Co1,811$157.5K0.00%00.0%Unchanged
ZRC Wealth Management, LLC1,971$171.4K0.06%00.0%Unchanged
Acadian Asset Management LLC2,218$192.0K0.00%−3,887−63.7%Reduced
Centaurus Financial, Inc.2,314$201.0K0.01%−75−3.1%Reduced
Verdad Advisers, LP2,445$212.6K0.24%+2,445New
Cornerstone Partners Capital Management, LLC2,462$214.1K0.53%+2,462New
Integrated Wealth Concepts LLC2,480$215.7K0.00%+2,480New
Northwest & Ethical Investments L.P.2,491$216.6K0.01%+2,491New
CWM, LLC2,536$220.6K0.00%−231−8.3%Reduced
Two Sigma Securities, LLC2,545$221.3K0.03%−2,398−48.5%Reduced
DRW Securities, LLC2,562$222.8K0.01%+2,562New
Blackstone Group Inc.2,600$226.1K0.00%+2,600New
CIBC Bancorp USA Inc.2,663$231.6K0.00%+2,663New
MAI Capital Management2,710$235.7K0.00%+2,708+135,400.0%Added
CIBC Asset Management Inc2,848$247.7K0.00%00.0%Unchanged
Cim Investment Mangement Inc2,993$260.3K0.07%00.0%Unchanged
Allianz Asset Management GmbH3,000$260.9K0.00%−5,000−62.5%Reduced
Ethic Inc.3,003$261.2K0.00%+3,003New
Chicago Partners Investment Group LLC3,125$266.2K0.01%+386+14.1%Added
Leo Wealth, LLC3,088$268.6K0.02%−3,864−55.6%Reduced
JustInvest LLC3,102$269.8K0.00%+723+30.4%Added
Cerity Partners LLC3,215$279.6K0.00%−449−12.3%Reduced
Marex Group plc3,288$286.0K0.00%+3,288New
Swiss Life Asset Management Ltd3,341$290.6K0.00%+688+25.9%Added
Mirae Asset Global Investments Co., Ltd.3,562$309.8K0.00%+319+9.8%Added
Freestone Capital Holdings, LLC3,700$321.8K0.01%00.0%Unchanged
Brevan Howard Capital Management LP3,777$328.5K0.00%+3,777New
Bank of Montreal3,801$330.6K0.00%+3,801New
Quantinno Capital Management LP3,851$334.9K0.00%+20+0.5%Added
Ensign Peak Advisors, Inc3,859$335.6K0.00%00.0%Unchanged
Fox Run Management, L.L.C.4,499$347.5K0.06%+4,499New
Centiva Capital, LP4,000$347.9K0.02%+4,000New
Abel Hall, LLC4,015$349.2K0.07%+1,875+87.6%Added
Amundi4,017$349.4K0.00%+4,017New
Man Group plc4,022$349.8K0.00%−5,536−57.9%Reduced
Jones Financial Companies LLLP4,918$372.9K0.00%+4,687+2,029.0%Added
Two Sigma Investments, LP4,300$374.0K0.00%+4,300New
Ameritas Investment Partners, Inc.4,365$379.6K0.01%00.0%Unchanged