Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 291
- +48 vs. Q4 2025
- Shares held
- 31.8M
- +3.79M (+13.5%) vs. Q4 2025
- Total value
- $10.2B
- +$1.98B (+24.0%) vs. Q4 2025
- New holders
- 80
- 121 more added
- Sold out
- 32
- 68 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 3,458,863 | $1.11B | 0.53% | +218,777+6.8% | Added |
| Orbis Allan Gray Ltd | 2,472,480 | $796.6M | 3.36% | +1,217,318+97.0% | Added |
| BlackRock, Inc. | 2,324,929 | $749.1M | 0.01% | +246,429+11.9% | Added |
| FMR LLC | 2,160,943 | $696.2M | 0.04% | +802,268+59.0% | Added |
| Perceptive Advisors LLC | 2,035,986 | $656.0M | 12.96% | +40,000+2.0% | Added |
| Baker Bros. Advisors LP | 1,753,198 | $564.9M | 3.24% | +626,710+55.6% | Added |
| Vanguard Capital Management LLC | 1,221,944 | $393.7M | 0.01% | +1,221,944 | New |
| Deerfield Management Company, L.P. (Series C) | 963,351 | $310.4M | 3.66% | +60,000+6.6% | Added |
| Driehaus Capital Management LLC | 949,225 | $305.8M | 2.25% | +16,164+1.7% | Added |
| Cormorant Asset Management, LP | 885,500 | $285.3M | 14.38% | −64,500−6.8% | Reduced |
| State Street Corp | 884,238 | $284.9M | 0.01% | +2,023+0.2% | Added |
| Morgan Stanley | 833,491 | $268.5M | 0.02% | −56,398−6.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 815,739 | $262.8M | 0.41% | −149,574−15.5% | Reduced |
| Vanguard Portfolio Management LLC | 756,748 | $243.8M | 0.01% | +756,748 | New |
| Goldman Sachs Group Inc | 710,734 | $229.0M | 0.03% | −5,450−0.8% | Reduced |
| Geode Capital Management, LLC | 650,904 | $209.8M | 0.01% | +88,525+15.7% | Added |
| Price T Rowe Associates Inc | 630,852 | $203.3M | 0.02% | −155,135−19.7% | Reduced |
| Bank of America Corp | 534,604 | $172.2M | 0.01% | +11,841+2.3% | Added |
| Ra Capital Management, L.P. | 373,787 | $120.4M | 1.28% | 00.0% | Unchanged |
| Hood River Capital Management LLC | 358,618 | $115.5M | 1.16% | +69,151+23.9% | Added |
| Vivo Capital, LLC | 338,895 | $109.2M | 9.08% | +10,000+3.0% | Added |
| Soleus Capital Management, L.P. | 330,517 | $106.5M | 4.31% | −32,449−8.9% | Reduced |
| Logos Global Management LP | 285,000 | $91.8M | 4.73% | −90,000−24.0% | Reduced |
| Pictet Asset Management Holding SA | 286,644 | $91.4M | 0.10% | +46,056+19.1% | Added |
| Franklin Resources Inc | 276,123 | $89.0M | 0.02% | −79,951−22.5% | Reduced |
| Northern Trust Corp | 227,934 | $73.4M | 0.01% | +35,650+18.5% | Added |
| Charles Schwab Investment Management Inc | 215,447 | $69.4M | 0.01% | +17,146+8.6% | Added |
| Woodline Partners LP | 200,013 | $64.4M | 0.24% | +94,601+89.7% | Added |
| T. Rowe Price Investment Management, Inc. | 175,237 | $56.5M | 0.04% | −101,155−36.6% | Reduced |
| Wellington Management Group LLP | 174,350 | $56.2M | 0.01% | −2,212−1.3% | Reduced |
| OrbiMed Advisors LLC | 172,500 | $55.6M | 1.26% | +78,000+82.5% | Added |
| Standard Life Aberdeen plc | 172,484 | $55.6M | 0.09% | +37,492+27.8% | Added |
| Affinity Asset Advisors, LLC | 170,000 | $54.8M | 3.21% | −15,000−8.1% | Reduced |
| Vanguard Fiduciary Trust Co | 169,902 | $54.7M | 0.01% | +169,902 | New |
| BNP Paribas Arbitrage, SA | 143,082 | $46.1M | 0.03% | +138,456+2,993.0% | Added |
| American Century Companies Inc | 128,254 | $41.3M | 0.02% | +52,888+70.2% | Added |
| Qube Research & Technologies Ltd | 128,228 | $41.3M | 0.06% | −40,669−24.1% | Reduced |
| ArrowMark Colorado Holdings LLC | 117,851 | $38.0M | 1.01% | +87,851+292.8% | Added |
| UBS Group AG | 108,446 | $34.9M | 0.01% | +19,246+21.6% | Added |
| Velan Capital Investment Management LP | 100,781 | $32.5M | 20.34% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 87,047 | $28.0M | 0.01% | +9,150+11.7% | Added |
| Acuta Capital Partners, LLC | 84,901 | $27.4M | 19.46% | +1,865+2.2% | Added |
| MetLife Investment Management | 80,930 | $26.1M | 0.13% | +68,506+551.4% | Added |
| Alyeska Investment Group, L.P. | 72,178 | $23.3M | 0.07% | −2,198−3.0% | Reduced |
| Nuveen, LLC | 72,043 | $23.2M | 0.01% | +22,073+44.2% | Added |
| Ikarian Capital, LLC | 71,581 | $23.1M | 3.30% | −15,000−17.3% | Reduced |
| Silverarc Capital Management, LLC | 71,552 | $23.1M | 2.72% | −10,913−13.2% | Reduced |
| JPMorgan Chase & Co | 80,180 | $22.2M | 0.00% | +24,880+45.0% | Added |
| Ensign Peak Advisors, Inc | 68,383 | $22.0M | 0.04% | +4,100+6.4% | Added |
| 72 Investment Holdings, LLC | 65,933 | $21.2M | 42.83% | 00.0% | Unchanged |
| Sofinnova Investments, Inc. | 63,680 | $20.5M | 1.03% | −62,042−49.3% | Reduced |
| Candriam Luxembourg S.C.A. | 63,628 | $20.5M | 0.11% | −46,962−42.5% | Reduced |
| Invesco Ltd. | 61,397 | $19.8M | 0.00% | −15,691−20.4% | Reduced |
| AQR Capital Management LLC | 58,656 | $18.9M | 0.01% | +29,828+103.5% | Added |
| Deutsche Bank AG | 57,779 | $18.6M | 0.01% | +6,968+13.7% | Added |
| StemPoint Capital LP | 56,267 | $18.1M | 3.48% | +35,200+167.1% | Added |
| Frontier Capital Management Co LLC | 53,365 | $17.2M | 0.18% | +53,365 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 47,432 | $15.3M | 0.03% | +10,055+26.9% | Added |
| Swiss National Bank | 46,700 | $15.0M | 0.01% | +6,200+15.3% | Added |
| Boxer Capital Management, LLC | 46,457 | $15.0M | 1.97% | 00.0% | Unchanged |
| Exome Asset Management LLC | 45,469 | $14.6M | 8.62% | −12,653−21.8% | Reduced |
| Marshall Wace, LLP | 45,149 | $14.5M | 0.02% | −24,093−34.8% | Reduced |
| KVP Capital Advisors, LP | 42,900 | $13.8M | 10.32% | 00.0% | Unchanged |
| First Turn Management, LLC | 42,441 | $13.7M | 1.53% | +6,692+18.7% | Added |
| California Public Employees Retirement System | 42,163 | $13.6M | 0.01% | +42,163 | New |
| Canada Pension Plan Investment Board | 40,130 | $12.9M | 0.01% | −29,582−42.4% | Reduced |
| Integral Health Asset Management, LLC | 40,000 | $12.9M | 0.68% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 38,640 | $12.4M | 0.21% | −28,460−42.4% | Reduced |
| UBS Asset Management Americas Inc | 38,145 | $12.3M | 0.00% | +2,857+8.1% | Added |
| SummitTX Capital, L.P. | 36,838 | $11.9M | 0.38% | −4,791−11.5% | Reduced |
| PFM Health Sciences, LP | 35,438 | $11.4M | 1.20% | +4,275+13.7% | Added |
| TD Asset Management Inc | 35,146 | $11.3M | 0.01% | −11,000−23.8% | Reduced |
| Burkehill Global Management, LP | 35,000 | $11.3M | 0.56% | +10,000+40.0% | Added |
| First Trust Advisors LP | 33,335 | $10.7M | 0.01% | −55,369−62.4% | Reduced |
| B Group, Inc. | 33,237 | $10.7M | 7.94% | 00.0% | Unchanged |
| Rhumbline Advisers | 32,879 | $10.6M | 0.01% | +4,555+16.1% | Added |
| Ally Bridge Group (NY) LLC | 32,810 | $10.6M | 10.50% | +12,928+65.0% | Added |
| Ameriprise Financial Inc | 31,220 | $10.1M | 0.00% | +8,505+37.4% | Added |
| Dimensional Fund Advisors LP | 31,161 | $10.0M | 0.00% | +7,618+32.4% | Added |
| Prudential Financial Inc | 30,510 | $9.83M | 0.01% | +15,648+105.3% | Added |
| Manufacturers Life Insurance Company, The | 30,093 | $9.70M | 0.01% | −3,198−9.6% | Reduced |
| Lord, Abbett & Co. LLC | 29,619 | $9.54M | 0.03% | −1,137−3.7% | Reduced |
| SEI Investments Co | 29,525 | $9.51M | 0.01% | +13,729+86.9% | Added |
| Voya Investment Management LLC | 28,134 | $9.06M | 0.01% | +14,479+106.0% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 27,744 | $8.89M | 0.01% | +2,185+8.5% | Added |
| California State Teachers Retirement System | 27,477 | $8.85M | 0.01% | +7,806+39.7% | Added |
| HighVista Strategies LLC | 26,323 | $8.48M | 2.34% | +482+1.9% | Added |
| Neuberger Berman Group LLC | 25,960 | $8.36M | 0.01% | +282+1.1% | Added |
| Alliancebernstein L.P. | 27,700 | $8.16M | 0.00% | +2,630+10.5% | Added |
| University of Wisconsin Foundation | 25,215 | $8.12M | 7.21% | +25,215 | New |
| Congress Asset Management Co | 24,839 | $8.00M | 0.06% | −6,407−20.5% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 23,251 | $7.49M | 0.11% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 23,112 | $7.45M | 0.01% | +2,500+12.1% | Added |
| Ishara Investments LP | 22,550 | $7.27M | 7.34% | −17,450−43.6% | Reduced |
| Vanguard Asset Management, Ltd | 22,000 | $7.09M | 0.01% | +22,000 | New |
| Moody Aldrich Partners LLC | 21,688 | $6.99M | 1.26% | −20,043−48.0% | Reduced |
| Atom Investors LP | 21,196 | $6.83M | 0.49% | +4,709+28.6% | Added |
| EAM Investors, LLC | 18,995 | $6.12M | 0.71% | −1,946−9.3% | Reduced |
| Legal & General Group Plc | 18,482 | $5.95M | 0.00% | +501+2.8% | Added |
| Two Sigma Investments, LP | 17,598 | $5.67M | 0.00% | −5,500−23.8% | Reduced |