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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
113
+3 vs. Q1 2024
Shares held
18.4M
+2.51M (+15.7%) vs. Q1 2024
Total value
$762.1M
−$209.2M (−21.5%) vs. Q1 2024
New holders
38
43 more added
Sold out
35
25 more reduced

1 institution that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 113 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2024: $762.1M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2024.

Institutions holding PRAX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.1,294,000$53.5M0.00%+1,072,255+483.6%Added
Ra Capital Management, L.P.1,235,599$51.1M0.68%+407,219+49.2%Added
Adage Capital Partners GP, L.L.C.1,134,083$46.9M0.09%−258,945−18.6%Reduced
Point72 Asset Management, L.P.1,051,701$43.5M0.14%+97,561+10.2%Added
Vanguard Group Inc977,145$40.4M0.00%+233,076+31.3%Added
Price T Rowe Associates Inc938,579$38.8M0.00%+402,580+75.1%Added
State Street Corp819,142$33.9M0.00%+774,634+1,740.4%Added
Perceptive Advisors LLC750,230$31.0M0.75%−71,359−8.7%Reduced
Verition Fund Management LLC748,320$31.0M0.24%+202,912+37.2%Added
VR Adviser, LLC706,131$29.2M1.86%+50.0%Added
Cormorant Asset Management, LP685,000$28.3M1.65%−625,000−47.7%Reduced
Soleus Capital Management, L.P.533,015$22.0M1.94%+495,747+1,330.2%Added
PFM Health Sciences, LP453,146$18.7M1.02%−24,459−5.1%Reduced
Vestal Point Capital, LP440,000$18.2M1.36%+230,000+109.5%Added
Kingdon Capital Management, L.L.C.415,000$17.2M2.65%+65,000+18.6%Added
Geode Capital Management, LLC395,059$16.3M0.00%+260,342+193.3%Added
Deep Track Capital, LP389,546$16.1M0.48%+389,546New
Janus Henderson Group PLC381,685$15.9M0.01%+71,626+23.1%Added
Velan Capital Investment Management LP350,666$14.5M8.31%00.0%Unchanged
5AM Venture Management, LLC340,000$14.1M3.15%00.0%Unchanged
FMR LLC290,979$12.0M0.00%−151,642−34.3%Reduced
Sphera Funds Management Ltd.283,424$11.7M1.91%+106,285+60.0%Added
Driehaus Capital Management LLC264,688$10.9M0.11%−1,808−0.7%Reduced
Octagon Capital Advisors LP260,000$10.8M1.77%00.0%Unchanged
Marshall Wace, LLP248,381$10.3M0.01%+127,357+105.2%Added
Franklin Resources Inc239,898$9.92M0.00%+94,603+65.1%Added
CIBC Asset Management Inc192,667$7.97M0.03%+363+0.2%Added
Morgan Stanley184,319$7.62M0.00%+84,183+84.1%Added
Nuveen Asset Management, LLC174,667$7.22M0.00%+174,667New
Acuta Capital Partners, LLC164,431$6.80M5.73%+2,129+1.3%Added
Ally Bridge Group (NY) LLC153,379$6.34M3.78%−6,107−3.8%Reduced
Baker Bros. Advisors LP131,533$5.44M0.07%00.0%Unchanged
Goldman Sachs Group Inc130,997$5.42M0.00%+32,362+32.8%Added
Millennium Management LLC90,909$3.76M0.00%−86,043−48.6%Reduced
Qube Research & Technologies Ltd90,693$3.75M0.01%−42,249−31.8%Reduced
Renaissance Technologies LLC75,433$3.12M0.01%+63,329+523.2%Added
Tri Locum Partners LP75,319$3.12M0.79%−31,175−29.3%Reduced
Silverarc Capital Management, LLC67,296$2.78M0.69%−123,260−64.7%Reduced
72 Investment Holdings, LLC65,933$2.73M6.85%00.0%Unchanged
Jacobs Levy Equity Management, Inc63,361$2.62M0.01%+11,813+22.9%Added
Wellington Management Group LLP51,513$2.13M0.00%+11,948+30.2%Added
TD Asset Management Inc51,312$2.12M0.00%+16,312+46.6%Added
Bank of New York Mellon Corp49,510$2.05M0.00%+49,510New
Northern Trust Corp48,069$1.99M0.00%+20,790+76.2%Added
Charles Schwab Investment Management Inc47,474$1.96M0.00%+40,785+609.7%Added
Rafferty Asset Management, LLC41,358$1.71M0.01%+41,358New
Ovata Capital Management Ltd40,000$1.65M0.90%+20,000+100.0%Added
Bank of America Corp38,554$1.59M0.00%+19,550+102.9%Added
UBS Oconnor LLC35,729$1.48M0.04%+1,000+2.9%Added
Manufacturers Life Insurance Company, The35,308$1.46M0.00%+15,443+77.7%Added
Voloridge Investment Management, LLC35,223$1.46M0.01%+7,556+27.3%Added
Jane Street Group, LLC32,093$1.33M0.00%−14,973−31.8%Reduced
Norges Bank32,005$1.32M0.00%+27,005+540.1%Added
Swiss National Bank32,000$1.32M0.00%+32,000New
StemPoint Capital LP29,259$1.21M0.36%+2,366+8.8%Added
UBS Group AG26,777$1.11M0.00%+26,769+334,612.5%Added
Moody Aldrich Partners LLC24,381$1.01M0.20%+24,381New
Two Sigma Investments, LP23,966$991.2K0.00%+594+2.5%Added
Trexquant Investment LP22,807$943.3K0.01%+18,464+425.1%Added
Citadel Advisors LLC22,646$936.6K0.00%−3,362−12.9%Reduced
Rhumbline Advisers22,192$917.9K0.00%+22,040+14,500.0%Added
UBS Asset Management Americas Inc21,882$905.0K0.00%+21,882New
D. E. Shaw & Co., Inc.21,077$871.7K0.00%+21,077New
Hussman Strategic Advisors, Inc.21,000$868.6K0.24%+21,000New
Assenagon Asset Management S.A.19,761$817.3K0.00%−51,492−72.3%Reduced
Alliancebernstein L.P.18,040$746.1K0.00%+18,040New
PCG Wealth Advisors, LLC17,441$721.4K0.31%+4,524+35.0%Added
Barclays PLC16,371$677.1K0.00%−74−0.4%Reduced
Alpine Global Management, LLC16,328$675.3K0.12%+16,328New
California State Teachers Retirement System15,945$659.5K0.00%+15,945New
Jump Financial, LLC14,321$592.3K0.01%+10,872+315.2%Added
Legal & General Group Plc14,041$580.7K0.00%+14,041New
Squarepoint Ops LLC13,348$552.1K0.00%+6,942+108.4%Added
Alps Advisors Inc13,342$551.8K0.00%+13,342New
Engineers Gate Manager LP12,659$523.6K0.01%+8,415+198.3%Added
State of Wisconsin Investment Board11,950$494.3K0.00%+11,950New
Ballentine Partners, LLC10,911$451.3K0.01%+10,911New
Corebridge Financial, Inc.9,277$383.8K0.00%+9,277New
Invesco Ltd.8,812$364.5K0.00%−86,369−90.7%Reduced
Deutsche Bank AG7,909$327.1K0.00%+7,757+5,103.3%Added
Profund Advisors LLC7,686$317.9K0.01%+7,686New
Citigroup Inc7,611$314.8K0.00%−7,507−49.7%Reduced
JPMorgan Chase & Co7,366$304.7K0.00%−44,006−85.7%Reduced
New York State Common Retirement Fund7,000$289.5K0.00%+7,000New
Bank of Montreal6,765$284.5K0.00%+6,765New
Dimensional Fund Advisors LP6,888$284.2K0.00%−8,152−54.2%Reduced
Man Group plc6,658$275.4K0.00%−9,263−58.2%Reduced
Boothbay Fund Management, LLC6,368$263.4K0.01%−36,435−85.1%Reduced
State Board of Administration of Florida Retirement System6,270$259.3K0.00%+6,270New
Wells Fargo & Company6,077$251.3K0.00%+5,423+829.2%Added
Voya Investment Management LLC5,824$240.9K0.00%+5,824New
Windmill Hill Asset Management Ltd5,268$217.9K0.09%00.0%Unchanged
Standard Life Aberdeen plc4,999$206.8K0.00%00.0%Unchanged
MetLife Investment Management4,423$182.9K0.00%+4,423New
Fred Alger Management, LLC2,595$107.3K0.00%−44,446−94.5%Reduced
Virtus ETF Advisers LLC2,260$93.5K0.05%+2,260New
BNP Paribas Arbitrage, SA2,029$83.9K0.00%−4,721−69.9%Reduced
Russell Investments Group, Ltd.2,000$82.7K0.00%+2,000New
Quarry LP2,000$82.7K0.03%+2,000New
Ameritas Investment Partners, Inc.1,689$69.9K0.00%+1,689New