Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 152
- +9 vs. Q2 2025
- Shares held
- 24.7M
- +519.5K (+2.2%) vs. Q2 2025
- Total value
- $1.31B
- +$291.9M (+28.8%) vs. Q2 2025
- New holders
- 27
- 60 more added
- Sold out
- 18
- 45 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 2,763,859 | $146.5M | 0.07% | +230,454+9.1% | Added |
| Adage Capital Partners GP, L.L.C. | 2,374,085 | $125.8M | 0.20% | +399,500+20.2% | Added |
| BlackRock, Inc. | 1,801,080 | $95.5M | 0.00% | +210,952+13.3% | Added |
| Perceptive Advisors LLC | 1,564,554 | $82.9M | 2.40% | +811,633+107.8% | Added |
| Point72 Asset Management, L.P. | 1,495,986 | $79.3M | 0.17% | +541,911+56.8% | Added |
| Vanguard Group Inc | 1,267,286 | $67.2M | 0.00% | +51,642+4.2% | Added |
| Price T Rowe Associates Inc | 1,003,490 | $53.2M | 0.01% | −469,585−31.9% | Reduced |
| Cormorant Asset Management, LP | 1,000,000 | $53.0M | 3.66% | −625,000−38.5% | Reduced |
| State Street Corp | 907,108 | $48.1M | 0.00% | +209,015+29.9% | Added |
| Soleus Capital Management, L.P. | 859,166 | $45.5M | 2.43% | −107,574−11.1% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 840,851 | $44.6M | 0.68% | +153,920+22.4% | Added |
| Baker Bros. Advisors LP | 689,488 | $36.5M | 0.26% | 00.0% | Unchanged |
| Morgan Stanley | 643,495 | $34.1M | 0.00% | −582,844−47.5% | Reduced |
| Goldman Sachs Group Inc | 593,021 | $31.4M | 0.00% | +367,029+162.4% | Added |
| Driehaus Capital Management LLC | 500,551 | $26.5M | 0.19% | −30,437−5.7% | Reduced |
| Bank of America Corp | 482,861 | $25.6M | 0.00% | +29,458+6.5% | Added |
| Geode Capital Management, LLC | 457,032 | $24.2M | 0.00% | +5,301+1.2% | Added |
| Woodline Partners LP | 417,669 | $22.1M | 0.10% | +371,717+808.9% | Added |
| Assenagon Asset Management S.A. | 409,779 | $21.7M | 0.03% | −194,519−32.2% | Reduced |
| CIBC Asset Management Inc | 388,759 | $20.6M | 0.06% | 00.0% | Unchanged |
| Franklin Resources Inc | 314,157 | $16.7M | 0.00% | +70.0% | Added |
| Vivo Capital, LLC | 198,895 | $10.5M | 0.85% | +31,295+18.7% | Added |
| Sofinnova Investments, Inc. | 172,833 | $9.16M | 0.56% | +157,116+999.7% | Added |
| 5AM Venture Management, LLC | 170,000 | $9.01M | 3.30% | 00.0% | Unchanged |
| Northern Trust Corp | 168,353 | $8.92M | 0.00% | −45,359−21.2% | Reduced |
| Charles Schwab Investment Management Inc | 161,661 | $8.57M | 0.00% | +9,217+6.0% | Added |
| Algert Global LLC | 160,818 | $8.52M | 0.14% | +133,248+483.3% | Added |
| Alyeska Investment Group, L.P. | 141,516 | $7.50M | 0.02% | +16,516+13.2% | Added |
| Velan Capital Investment Management LP | 132,805 | $7.04M | 6.61% | −16,529−11.1% | Reduced |
| Logos Global Management LP | 125,000 | $6.63M | 0.65% | −100,000−44.4% | Reduced |
| Readystate Asset Management LP | 109,177 | $5.79M | 0.28% | +109,177 | New |
| Exome Asset Management LLC | 101,996 | $5.41M | 3.57% | +42,994+72.9% | Added |
| UBS Group AG | 96,812 | $5.13M | 0.00% | +10,278+11.9% | Added |
| HighVista Strategies LLC | 95,002 | $5.04M | 1.23% | +27,714+41.2% | Added |
| Barclays PLC | 76,637 | $4.06M | 0.00% | −12,087−13.6% | Reduced |
| Kennedy Capital Management, Inc. | 76,218 | $4.04M | 0.09% | +5,773+8.2% | Added |
| Tri Locum Partners LP | 75,986 | $4.03M | 0.93% | −119,446−61.1% | Reduced |
| Marshall Wace, LLP | 68,141 | $3.61M | 0.00% | +68,141 | New |
| 72 Investment Holdings, LLC | 65,933 | $3.49M | 5.14% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 62,866 | $3.33M | 0.02% | −805−1.3% | Reduced |
| Wellington Management Group LLP | 61,241 | $3.25M | 0.00% | +5,360+9.6% | Added |
| PFM Health Sciences, LP | 60,578 | $3.21M | 0.27% | −24,135−28.5% | Reduced |
| Sphera Funds Management Ltd. | 57,901 | $3.07M | 0.73% | −51,856−47.2% | Reduced |
| Qube Research & Technologies Ltd | 57,304 | $3.04M | 0.00% | +57,304 | New |
| Bank of New York Mellon Corp | 56,288 | $2.98M | 0.00% | +3,735+7.1% | Added |
| Silverarc Capital Management, LLC | 51,210 | $2.71M | 0.39% | +41,210+412.1% | Added |
| Acuta Capital Partners, LLC | 49,751 | $2.64M | 2.72% | −24,336−32.8% | Reduced |
| FMR LLC | 43,211 | $2.29M | 0.00% | +5,111+13.4% | Added |
| TD Asset Management Inc | 40,884 | $2.17M | 0.00% | −23,054−36.1% | Reduced |
| Boothbay Fund Management, LLC | 39,660 | $2.10M | 0.05% | −78,461−66.4% | Reduced |
| Nuveen, LLC | 38,549 | $2.04M | 0.00% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 37,573 | $1.99M | 0.01% | +12,768+51.5% | Added |
| Dimensional Fund Advisors LP | 37,414 | $1.98M | 0.00% | +37,414 | New |
| Manufacturers Life Insurance Company, The | 35,829 | $1.90M | 0.00% | −20,302−36.2% | Reduced |
| Swiss National Bank | 35,500 | $1.88M | 0.00% | +4,700+15.3% | Added |
| SummitTX Capital, L.P. | 34,928 | $1.85M | 0.08% | +34,928 | New |
| Y-Intercept (Hong Kong) Ltd | 32,186 | $1.71M | 0.04% | +32,186 | New |
| Jane Street Group, LLC | 31,687 | $1.68M | 0.00% | +18,684+143.7% | Added |
| B Group, Inc. | 31,500 | $1.67M | 1.60% | −3,500−10.0% | Reduced |
| Congress Asset Management Co | 30,439 | $1.61M | 0.01% | +30,439 | New |
| Susquehanna International Group, LLP | 29,337 | $1.55M | 0.00% | −17,590−37.5% | Reduced |
| First Trust Advisors LP | 28,966 | $1.54M | 0.00% | +28,966 | New |
| Ikarian Capital, LLC | 28,571 | $1.51M | 0.34% | −248,379−89.7% | Reduced |
| Prelude Capital Management, LLC | 28,102 | $1.49M | 0.12% | +8,202+41.2% | Added |
| Knott David M Jr | 28,000 | $1.48M | 0.62% | +28,000 | New |
| Rhumbline Advisers | 26,794 | $1.42M | 0.00% | −547−2.0% | Reduced |
| JPMorgan Chase & Co | 26,208 | $1.39M | 0.00% | +12,270+88.0% | Added |
| UBS Asset Management Americas Inc | 23,756 | $1.26M | 0.00% | −73,189−75.5% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 23,251 | $1.23M | 0.02% | +17,501+304.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 22,836 | $1.21M | 0.00% | −1,037−4.3% | Reduced |
| Simplex Trading, LLC | 22,529 | $1.19M | 0.03% | −2,799−11.1% | Reduced |
| AQR Capital Management LLC | 21,904 | $1.16M | 0.00% | +7,324+50.2% | Added |
| Dark Forest Capital Management LP | 21,684 | $1.15M | 0.04% | +21,684 | New |
| Invesco Ltd. | 20,868 | $1.11M | 0.00% | +4,929+30.9% | Added |
| Quarry LP | 20,001 | $1.06M | 0.26% | +15,201+316.7% | Added |
| D. E. Shaw & Co., Inc. | 19,796 | $1.05M | 0.00% | +740+3.9% | Added |
| California State Teachers Retirement System | 18,583 | $984.9K | 0.00% | +2,237+13.7% | Added |
| Alliancebernstein L.P. | 18,060 | $957.2K | 0.00% | +20+0.1% | Added |
| Legal & General Group Plc | 16,824 | $891.7K | 0.00% | +154+0.9% | Added |
| Group One Trading, L.P. | 16,628 | $881.3K | 0.03% | +16,628 | New |
| American Century Companies Inc | 15,268 | $809.2K | 0.00% | +15,268 | New |
| PCG Wealth Advisors, LLC | 14,483 | $767.6K | 0.22% | +14,483 | New |
| Jacobs Levy Equity Management, Inc | 13,898 | $736.6K | 0.00% | −31,184−69.2% | Reduced |
| Deutsche Bank AG | 13,856 | $734.4K | 0.00% | +1,732+14.3% | Added |
| Wells Fargo & Company | 13,605 | $721.1K | 0.00% | +2,353+20.9% | Added |
| SG Americas Securities, LLC | 13,496 | $715.0K | 0.00% | +13,496 | New |
| HSBC Holdings PLC | 11,172 | $594.7K | 0.00% | +11,172 | New |
| MetLife Investment Management | 10,520 | $557.6K | 0.00% | 00.0% | Unchanged |
| Hussman Strategic Advisors, Inc. | 10,500 | $556.5K | 0.12% | 00.0% | Unchanged |
| Alps Advisors Inc | 10,424 | $552.5K | 0.00% | −570−5.2% | Reduced |
| State of Wisconsin Investment Board | 9,033 | $478.7K | 0.00% | −5,726−38.8% | Reduced |
| Trexquant Investment LP | 8,905 | $472.0K | 0.00% | +8,905 | New |
| Freestone Grove Partners LP | 8,269 | $438.3K | 0.00% | +8,269 | New |
| Profund Advisors LLC | 8,079 | $428.2K | 0.01% | +2,818+53.6% | Added |
| Citadel Advisors LLC | 7,798 | $413.3K | 0.00% | −2,568−24.8% | Reduced |
| Intech Investment Management LLC | 7,754 | $411.0K | 0.00% | −965−11.1% | Reduced |
| Nisa Investment Advisors, LLC | 7,129 | $377.8K | 0.00% | +6,500+1,033.4% | Added |
| Phoenix Holdings Ltd. | 6,817 | $361.5K | 0.00% | +6,817 | New |
| Creative Planning | 6,660 | $353.0K | 0.00% | +165+2.5% | Added |
| New York State Common Retirement Fund | 6,600 | $349.8K | 0.00% | 00.0% | Unchanged |