Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 309
- +20 vs. Q1 2026
- Shares held
- 33.7M
- +5.40M (+19.0%) vs. Q1 2026
- Total value
- $11.3B
- +$2.17B (+23.8%) vs. Q1 2026
- New holders
- 59
- 123 more added
- Sold out
- 39
- 93 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Jupiter Topco LLC | 3,421,374 | $1.15B | 0.47% | +3,421,374 | New |
| FMR LLC | 2,316,907 | $775.7M | 0.03% | +155,964+7.2% | Added |
| BlackRock, Inc. | 2,292,585 | $767.5M | 0.01% | −32,344−1.4% | Reduced |
| Perceptive Advisors LLC | 2,035,986 | $681.6M | 10.58% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,753,198 | $587.0M | 2.94% | 00.0% | Unchanged |
| Orbis Allan Gray Ltd | 1,529,788 | $512.2M | 1.76% | −942,692−38.1% | Reduced |
| Vanguard Portfolio Management LLC | 1,335,185 | $447.0M | 0.02% | +578,437+76.4% | Added |
| Vanguard Capital Management LLC | 1,235,299 | $413.6M | 0.01% | +13,355+1.1% | Added |
| State Street Corp | 1,026,443 | $343.7M | 0.01% | +142,205+16.1% | Added |
| Adage Capital Partners GP, L.L.C. | 1,015,480 | $340.0M | 0.48% | +199,741+24.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 963,351 | $322.5M | 3.36% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 959,048 | $321.1M | 1.86% | +9,823+1.0% | Added |
| Price T Rowe Associates Inc | 942,999 | $315.7M | 0.03% | +312,147+49.5% | Added |
| Morgan Stanley | 854,112 | $285.9M | 0.02% | +20,621+2.5% | Added |
| Geode Capital Management, LLC | 748,039 | $250.5M | 0.01% | +97,135+14.9% | Added |
| Cormorant Asset Management, LP | 640,000 | $214.3M | 10.98% | −245,500−27.7% | Reduced |
| Goldman Sachs Group Inc | 548,830 | $183.7M | 0.02% | −161,904−22.8% | Reduced |
| Bank of America Corp | 546,930 | $183.1M | 0.01% | +12,326+2.3% | Added |
| Invesco Ltd. | 537,548 | $180.0M | 0.01% | +476,151+775.5% | Added |
| Hood River Capital Management LLC | 425,167 | $142.3M | 1.03% | +66,549+18.6% | Added |
| Norges Bank | 346,969 | $116.2M | 0.01% | +346,969 | New |
| Franklin Resources Inc | 327,124 | $109.5M | 0.02% | +51,001+18.5% | Added |
| Pictet Asset Management Holding SA | 291,689 | $98.0M | 0.09% | +5,045+1.8% | Added |
| Polar Capital Holdings Plc | 279,131 | $93.5M | 0.26% | +279,131 | New |
| Vivo Capital, LLC | 271,116 | $90.8M | 8.29% | −67,779−20.0% | Reduced |
| Logos Global Management LP | 260,000 | $87.0M | 3.75% | −25,000−8.8% | Reduced |
| Northern Trust Corp | 240,887 | $80.6M | 0.01% | +12,953+5.7% | Added |
| American Century Companies Inc | 237,315 | $79.5M | 0.04% | +109,061+85.0% | Added |
| OrbiMed Advisors LLC | 230,100 | $77.0M | 1.46% | +57,600+33.4% | Added |
| Charles Schwab Investment Management Inc | 220,008 | $73.7M | 0.01% | +4,561+2.1% | Added |
| Westfield Capital Management Co LP | 218,898 | $73.3M | 0.24% | +218,236+32,966.2% | Added |
| Woodline Partners LP | 200,013 | $67.0M | 0.21% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 188,409 | $63.1M | 0.03% | +45,327+31.7% | Added |
| Vanguard Fiduciary Trust Co | 188,161 | $63.0M | 0.01% | +18,259+10.7% | Added |
| Affinity Asset Advisors, LLC | 185,000 | $61.9M | 3.03% | +15,000+8.8% | Added |
| Soleus Capital Management, L.P. | 177,517 | $59.4M | 2.05% | −153,000−46.3% | Reduced |
| Standard Life Aberdeen plc | 166,399 | $55.7M | 0.08% | −6,085−3.5% | Reduced |
| T. Rowe Price Investment Management, Inc. | 160,477 | $53.7M | 0.04% | −14,760−8.4% | Reduced |
| Qube Research & Technologies Ltd | 152,475 | $51.0M | 0.06% | +24,247+18.9% | Added |
| Marshall Wace, LLP | 137,008 | $45.9M | 0.04% | +91,859+203.5% | Added |
| UBS Group AG | 131,046 | $43.9M | 0.01% | +22,600+20.8% | Added |
| Wellington Management Group LLP | 125,867 | $42.1M | 0.01% | −48,483−27.8% | Reduced |
| Voya Investment Management LLC | 122,227 | $40.9M | 0.04% | +94,093+334.4% | Added |
| Nuveen, LLC | 108,032 | $36.2M | 0.01% | +35,989+50.0% | Added |
| Massachusetts Financial Services Co | 107,409 | $36.0M | 0.01% | +100,021+1,353.8% | Added |
| MetLife Investment Management | 90,543 | $30.3M | 0.14% | +9,613+11.9% | Added |
| Neuberger Berman Group LLC | 89,468 | $30.0M | 0.02% | +63,508+244.6% | Added |
| Velan Capital Investment Management LP | 88,781 | $29.7M | 18.21% | −12,000−11.9% | Reduced |
| Bank of New York Mellon Corp | 85,376 | $28.6M | 0.00% | −1,671−1.9% | Reduced |
| First Turn Management, LLC | 83,528 | $28.0M | 2.99% | +41,087+96.8% | Added |
| Acuta Capital Partners, LLC | 82,796 | $27.7M | 19.32% | −2,105−2.5% | Reduced |
| Alyeska Investment Group, L.P. | 80,846 | $27.1M | 0.07% | +8,668+12.0% | Added |
| ADAR1 Capital Management, LLC | 74,253 | $24.9M | 1.17% | +72,753+4,850.2% | Added |
| Frontier Capital Management Co LLC | 74,207 | $24.8M | 0.23% | +20,842+39.1% | Added |
| Ensign Peak Advisors, Inc | 72,952 | $24.4M | 0.04% | +4,569+6.7% | Added |
| Ikarian Capital, LLC | 72,842 | $24.4M | 3.99% | +1,261+1.8% | Added |
| Alliancebernstein L.P. | 71,518 | $23.0M | 0.01% | +43,818+158.2% | Added |
| 72 Investment Holdings, LLC | 65,933 | $22.1M | 44.18% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 65,679 | $22.0M | 2.45% | −5,873−8.2% | Reduced |
| Ameriprise Financial Inc | 64,295 | $21.5M | 0.00% | +33,075+105.9% | Added |
| Deutsche Bank AG | 64,263 | $21.5M | 0.01% | +6,484+11.2% | Added |
| Raymond James Financial Inc | 61,980 | $20.8M | 0.01% | +56,660+1,065.0% | Added |
| Candriam Luxembourg S.C.A. | 60,856 | $20.4M | 0.09% | −2,772−4.4% | Reduced |
| AQR Capital Management LLC | 58,446 | $19.6M | 0.01% | −210−0.4% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 56,840 | $19.0M | 0.03% | +56,840 | New |
| Russell Investments Group, Ltd. | 51,033 | $17.1M | 0.01% | +27,921+120.8% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 48,118 | $16.1M | 0.02% | +686+1.4% | Added |
| JPMorgan Chase & Co | 44,085 | $15.8M | 0.00% | −36,095−45.0% | Reduced |
| Boxer Capital Management, LLC | 46,457 | $15.6M | 1.17% | 00.0% | Unchanged |
| Swiss National Bank | 46,100 | $15.4M | 0.01% | −600−1.3% | Reduced |
| ArrowMark Colorado Holdings LLC | 46,030 | $15.4M | 0.64% | −71,821−60.9% | Reduced |
| California Public Employees Retirement System | 45,370 | $15.2M | 0.01% | +3,207+7.6% | Added |
| KVP Capital Advisors, LP | 42,900 | $14.4M | 10.54% | 00.0% | Unchanged |
| SEB Asset Management AB | 42,705 | $14.3M | 0.05% | +42,705 | New |
| Squarepoint Ops LLC | 42,501 | $14.2M | 0.03% | +40,491+2,014.5% | Added |
| SEI Investments Co | 40,117 | $13.4M | 0.01% | +10,592+35.9% | Added |
| Integral Health Asset Management, LLC | 40,000 | $13.4M | 0.55% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 38,684 | $13.0M | 0.17% | +44+0.1% | Added |
| PFM Health Sciences, LP | 38,575 | $12.9M | 1.12% | +3,137+8.9% | Added |
| StemPoint Capital LP | 37,243 | $12.5M | 2.16% | −19,024−33.8% | Reduced |
| UBS Asset Management Americas Inc | 36,187 | $12.1M | 0.00% | −1,958−5.1% | Reduced |
| Burkehill Global Management, LP | 35,000 | $11.7M | 0.42% | 00.0% | Unchanged |
| University of Wisconsin Foundation | 34,730 | $11.6M | 9.21% | +9,515+37.7% | Added |
| B Group, Inc. | 33,237 | $11.1M | 6.32% | 00.0% | Unchanged |
| Rhumbline Advisers | 32,347 | $10.8M | 0.01% | −532−1.6% | Reduced |
| Dimensional Fund Advisors LP | 31,574 | $10.6M | 0.00% | +413+1.3% | Added |
| HighVista Strategies LLC | 30,210 | $10.1M | 2.31% | +3,887+14.8% | Added |
| Lord, Abbett & Co. LLC | 29,662 | $9.93M | 0.03% | +43+0.1% | Added |
| Clearbridge Investments, LLC | 27,981 | $9.37M | 0.01% | +27,981 | New |
| Wells Fargo & Company | 27,889 | $9.34M | 0.00% | +16,275+140.1% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 27,185 | $9.12M | 0.01% | −559−2.0% | Reduced |
| Exome Asset Management LLC | 27,205 | $9.11M | 5.62% | −18,264−40.2% | Reduced |
| TD Asset Management Inc | 27,162 | $9.09M | 0.01% | −7,984−22.7% | Reduced |
| Capital Fund Management S.A. | 27,058 | $9.06M | 0.06% | +27,058 | New |
| California State Teachers Retirement System | 26,603 | $8.91M | 0.01% | −874−3.2% | Reduced |
| Manufacturers Life Insurance Company, The | 26,147 | $8.75M | 0.01% | −3,946−13.1% | Reduced |
| WCM Investment Management, LLC | 24,739 | $8.67M | 0.02% | +24,739 | New |
| Peregrine Capital Management LLC | 25,790 | $8.63M | 0.28% | +25,790 | New |
| Allianz Asset Management GmbH | 25,744 | $8.62M | 0.01% | +11,714+83.5% | Added |
| Castleark Management LLC | 24,390 | $8.17M | 0.22% | +24,390 | New |