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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
309
+20 vs. Q1 2026
Shares held
33.7M
+5.40M (+19.0%) vs. Q1 2026
Total value
$11.3B
+$2.17B (+23.8%) vs. Q1 2026
New holders
59
123 more added
Sold out
39
93 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 309 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2026: $11.3B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2026.

Institutions holding PRAX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Citigroup Inc23,599$7.90M0.00%+17,953+318.0%Added
Vanguard Asset Management, Ltd22,634$7.58M0.01%+634+2.9%Added
Ishara Investments LP22,550$7.55M5.65%00.0%Unchanged
Man Group plc21,164$7.09M0.01%+17,991+567.0%Added
Susquehanna Portfolio Strategies, LLC21,126$7.07M0.11%−2,125−9.1%Reduced
SummitTX Capital, L.P.19,779$6.62M0.17%−17,059−46.3%Reduced
Prudential Financial Inc19,541$6.54M0.01%−10,969−36.0%Reduced
Moody Aldrich Partners LLC19,066$6.38M1.15%−2,622−12.1%Reduced
Legal & General Group Plc19,030$6.37M0.00%+548+3.0%Added
Two Sigma Investments, LP18,758$6.28M0.00%+1,160+6.6%Added
Boothbay Fund Management, LLC17,968$6.02M0.12%+381+2.2%Added
Algert Global LLC17,478$5.85M0.07%+1,310+8.1%Added
J. Goldman & Co LP16,186$5.42M0.19%+522+3.3%Added
First Trust Advisors LP16,087$5.39M0.00%−17,248−51.7%Reduced
Mutual of America Capital Management LLC15,432$5.17M0.05%+2,959+23.7%Added
Victory Capital Management Inc15,160$5.08M0.00%+1,028+7.3%Added
State of Wisconsin Investment Board13,750$4.60M0.01%−892−6.1%Reduced
Creative Planning13,512$4.52M0.00%−2,774−17.0%Reduced
Nicholas Investment Partners, LP13,113$4.39M0.25%+9,165+232.1%Added
Atika Capital Management LLC12,900$4.32M0.43%+12,900New
Erste Asset Management GmbH12,200$4.28M0.03%+1,700+16.2%Added
Vanguard Global Advisers, LLC12,052$4.03M0.00%+717+6.3%Added
Connor, Clark & Lunn Investment Management Ltd.12,046$4.03M0.01%+4,852+67.4%Added
Rafferty Asset Management, LLC11,470$3.84M0.01%−3,718−24.5%Reduced
New York State Common Retirement Fund11,441$3.83M0.00%+2,692+30.8%Added
Readystate Asset Management LP10,548$3.53M0.14%+10,548New
Schonfeld Strategic Advisors LLC10,306$3.45M0.02%+10,306New
Handelsbanken Fonder AB9,840$3.29M0.01%+9,840New
Zurcher Kantonalbank (Zurich Cantonalbank)9,280$3.11M0.01%+5,231+129.2%Added
Nomura Asset Management International Inc.8,429$2.82M0.00%+8,429New
Cinctive Capital Management LP8,300$2.78M0.11%+8,300New
Virginia Retirement Systems Et Al8,060$2.70M0.02%+6,260+347.8%Added
Kornitzer Capital Management Inc8,020$2.69M0.06%+8,020New
Atom Investors LP7,859$2.63M0.23%−13,337−62.9%Reduced
Seven Fleet Capital Management LP7,540$2.52M0.42%+7,540New
State of New Jersey Common Pension Fund D7,429$2.49M0.01%−629−7.8%Reduced
Schroder Investment Management Group7,093$2.49M0.00%+7,093New
Police & Firemen's Retirement System of New Jersey7,414$2.48M0.02%+425+6.1%Added
Citadel Advisors LLC7,331$2.45M0.00%+7,331New
Polen Capital Management LLC7,252$2.43M0.02%−2,791−27.8%Reduced
Vestmark Advisory Solutions, Inc.6,681$2.24M0.02%00.0%Unchanged
Allspring Global Investments Holdings, LLC6,884$2.20M0.00%−1,652−19.4%Reduced
Royce & Associates LP6,544$2.19M0.02%+6,544New
RE Advisers Corp6,500$2.18M0.05%+3,200+97.0%Added
Sofinnova Investments, Inc.6,440$2.16M0.12%−57,240−89.9%Reduced
Fifth Third Bancorp6,359$2.13M0.00%+2,770+77.2%Added
Arizona State Retirement System6,340$2.12M0.01%−136−2.1%Reduced
State Board of Administration of Florida Retirement System6,306$2.11M0.00%+404+6.8%Added
Nisa Investment Advisors, LLC6,111$2.05M0.01%−169−2.7%Reduced
Profund Advisors LLC6,097$2.04M0.06%−984−13.9%Reduced
Barclays PLC6,095$2.04M0.00%−884−12.7%Reduced
Royal Bank of Canada6,065$2.03M0.00%+1,932+46.7%Added
Vanguard Investments Australia, Ltd.5,936$1.99M0.00%00.0%Unchanged
Intech Investment Management LLC5,612$1.88M0.02%−1,365−19.6%Reduced
KLP Kapitalforvaltning AS5,200$1.74M0.01%00.0%Unchanged
D. E. Shaw & Co., Inc.5,140$1.72M0.00%+5,140New
Ghisallo Capital Management LLC5,000$1.67M0.03%00.0%Unchanged
Carl P. Sherr & Co., LLC4,889$1.64M0.69%+3,917+403.0%Added
Lion Point Capital, LP4,450$1.49M7.13%00.0%Unchanged
China Universal Asset Management Co., Ltd.4,437$1.49M0.09%−505−10.2%Reduced
SG Americas Securities, LLC4,321$1.45M0.00%+3,469+407.2%Added
STRS Ohio4,300$1.44M0.01%+700+19.4%Added
ProShare Advisors LLC4,208$1.41M0.00%−780−15.6%Reduced
FORA Capital, LLC4,205$1.41M0.10%+793+23.2%Added
Hussman Strategic Advisors, Inc.4,200$1.41M0.32%00.0%Unchanged
Envestnet Asset Management Inc4,179$1.40M0.00%−683−14.0%Reduced
Glenmede Trust Co NA4,096$1.37M0.01%+686+20.1%Added
Coastal Bridge Advisors, LLC3,846$1.29M0.08%−60−1.5%Reduced
Guggenheim Capital LLC3,846$1.29M0.01%+1,176+44.0%Added
Quantinno Capital Management LP3,708$1.24M0.00%+388+11.7%Added
Susquehanna International Group, LLP3,594$1.20M0.00%−4,923−57.8%Reduced
Scientech Research LLC3,378$1.13M0.92%+2,709+404.9%Added
Integrated Quantitative Investments LLC3,173$1.06M0.17%+1,920+153.2%Added
Legato Capital Management LLC3,171$1.06M0.09%+2,501+373.3%Added
LPL Financial LLC3,152$1.06M0.00%+229+7.8%Added
New York Life Investment Management LLC3,137$1.05M0.01%+3,137New
State of Wyoming2,768$926.7K0.09%+2,768New
Quarry LP2,754$922.0K0.15%+4+0.1%Added
ACT Capital Management, LLC2,700$903.9K0.59%00.0%Unchanged
Teacher Retirement System of Texas2,688$899.9K0.00%−374−12.2%Reduced
Jump Financial, LLC2,621$877.5K0.01%+2,621New
Allstate Corp2,500$837.0K0.01%−1,012−28.8%Reduced
Artia Global Partners LP2,500$837.0K0.16%00.0%Unchanged
Xponance, Inc.2,476$828.9K0.01%+56+2.3%Added
Arrowpoint Investment Partners (Singapore) Pte. Ltd.2,461$823.9K0.24%−1,394−36.2%Reduced
Public Employees Retirement Association of Colorado2,390$800.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,322$777.4K0.02%+989+74.2%Added
Ameritas Investment Partners, Inc.2,281$763.7K0.02%+168+8.0%Added
Tudor Investment Corp Et Al2,183$730.8K0.00%+2,183New
Jain Global LLC2,170$726.5K0.01%+2,170New
Captrust Financial Advisors2,153$720.8K0.00%+2,153New
Wexford Capital LP2,000$669.6K0.09%+2,000New
Ethic Inc.1,972$660.2K0.01%−18−0.9%Reduced
Polymer Capital Management (US) LLC1,940$649.5K0.10%+1,940New
Principal Financial Group Inc1,922$643.5K0.00%+769+66.7%Added
Magnetar Financial LLC1,911$639.8K0.01%+1,911New
Balyasny Asset Management LLC1,880$629.4K0.00%+1,880New
Bellevue Group AG1,847$618.4K0.01%+90+5.1%Added
Federation des caisses Desjardins du Quebec1,831$613.0K0.00%+1,831New
Amundi1,715$574.2K0.00%−87−4.8%Reduced