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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
103
+3 vs. Q4 2021
Shares held
45.4M
+1.56M (+3.6%) vs. Q4 2021
Total value
$463.4M
−$399.8M (−46.3%) vs. Q4 2021
New holders
13
39 more added
Sold out
10
26 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 103 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ1 2022: $463.4M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2021.

Institutions holding PRAX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Blackstone Group Inc.4,894,109$50.0M0.13%00.0%Unchanged
FMR LLC4,602,871$47.0M0.00%+26,642+0.6%Added
Eventide Asset Management, LLC4,395,000$44.9M0.70%+584,401+15.3%Added
Janus Henderson Group PLC3,333,943$34.0M0.02%−8,626−0.3%Reduced
Vanguard Group Inc3,322,140$33.9M0.00%+29,697+0.9%Added
Vida Ventures Advisors, LLC2,939,329$30.0M17.45%00.0%Unchanged
BlackRock Inc.2,529,761$25.8M0.00%+33,065+1.3%Added
Avoro Capital Advisors LLC2,150,000$22.0M0.40%+370,000+20.8%Added
Alliancebernstein L.P.2,049,840$20.9M0.01%+176,330+9.4%Added
Citadel Advisors LLC1,550,306$15.8M0.02%−73,217−4.5%Reduced
State Street Corp1,393,386$14.2M0.00%+125,571+9.9%Added
Point72 Asset Management, L.P.1,328,943$13.6M0.06%−117,450−8.1%Reduced
Artal Group S.A.1,200,000$12.3M0.52%00.0%Unchanged
72 Investment Holdings, LLC988,995$10.1M11.05%00.0%Unchanged
PFM Health Sciences, LP864,819$8.83M0.34%+228,915+36.0%Added
Adage Capital Partners GP, L.L.C.792,081$8.09M0.02%+100,000+14.4%Added
Harvard Management Co Inc778,517$7.95M0.80%00.0%Unchanged
Cormorant Asset Management, LP752,406$7.68M0.59%00.0%Unchanged
Geode Capital Management, LLC627,288$6.40M0.00%+29,905+5.0%Added
Laurion Capital Management LP545,379$5.57M0.13%−7,200−1.3%Reduced
Kingdon Capital Management, L.L.C.414,489$4.23M0.72%00.0%Unchanged
Northern Trust Corp317,611$3.24M0.00%+3,291+1.0%Added
Woodline Partners LP308,746$3.15M0.05%00.0%Unchanged
Franklin Resources Inc274,812$2.81M0.00%00.0%Unchanged
Charles Schwab Investment Management Inc254,175$2.60M0.00%+6,414+2.6%Added
Novo Holdings A/S250,000$2.55M0.13%00.0%Unchanged
Nuveen Asset Management, LLC224,868$2.46M0.00%+6,253+2.9%Added
Verition Fund Management LLC236,374$2.41M0.05%+24,081+11.3%Added
Goldman Sachs Group Inc139,550$1.43M0.00%+63,664+83.9%Added
Raymond James & Associates118,334$1.21M0.00%+400.0%Added
Two Sigma Investments, LP114,263$1.17M0.00%−37,898−24.9%Reduced
Bank of New York Mellon Corp109,522$1.12M0.00%+1,940+1.8%Added
Bank of America Corp106,790$1.09M0.00%+14,454+15.7%Added
Endurant Capital Management LP79,452$811.0K0.24%−10,109−11.3%Reduced
Millennium Management LLC77,870$795.0K0.00%+43,634+127.5%Added
State of Wisconsin Investment Board75,800$774.0K0.00%+44,300+140.6%Added
Tekla Capital Management LLC75,000$766.0K0.03%00.0%Unchanged
Morgan Stanley72,098$737.0K0.00%+51,807+255.3%Added
UBS Group AG71,918$734.0K0.00%−14,187−16.5%Reduced
Renaissance Technologies LLC71,800$733.0K0.00%+58,700+448.1%Added
Rafferty Asset Management, LLC70,207$717.0K0.00%+2,716+4.0%Added
Two Sigma Advisers, LP57,300$585.0K0.00%−5,300−8.5%Reduced
Swiss National Bank53,100$542.0K0.00%+3,900+7.9%Added
Alps Advisors Inc46,747$477.0K0.01%−5,160−9.9%Reduced
Values First Advisors, Inc.45,990$470.0K0.30%+10,419+29.3%Added
Rhumbline Advisers41,376$422.0K0.00%+3,467+9.1%Added
JPMorgan Chase & Co33,795$345.0K0.00%+5,022+17.5%Added
California State Teachers Retirement System33,709$344.0K0.00%−3,372−9.1%Reduced
Alta Wealth Advisors LLC31,028$317.0K0.19%00.0%Unchanged
Citigroup Inc30,284$309.0K0.00%−50,381−62.5%Reduced
Trexquant Investment LP28,048$286.0K0.01%+12,062+75.5%Added
Price T Rowe Associates Inc27,527$281.0K0.00%+791+3.0%Added
New York State Common Retirement Fund21,711$222.0K0.00%+25+0.1%Added
Deutsche Bank AG21,243$217.0K0.00%−1,938−8.4%Reduced
State Board of Administration of Florida Retirement System20,861$213.0K0.00%00.0%Unchanged
Man Group plc20,300$207.0K0.00%+20,300New
Quantum Private Wealth, LLC20,161$205.0K0.09%00.0%Unchanged
MetLife Investment Management19,433$198.4K0.00%+6,340+48.4%Added
Cna Financial Corp18,741$191.0K0.06%+510+2.8%Added
Susquehanna International Group, LLP18,187$186.0K0.00%−8,465−31.8%Reduced
American International Group, Inc.16,539$169.0K0.00%−1,165−6.6%Reduced
Susquehanna Fundamental Investments, LLC16,453$168.0K0.00%−1,907−10.4%Reduced
Cubist Systematic Strategies, LLC16,072$164.0K0.00%+6,473+67.4%Added
Credit Suisse AG15,563$159.0K0.00%−964−5.8%Reduced
Manufacturers Life Insurance Company, The14,722$150.3K0.00%−3,305−18.3%Reduced
Dynamic Technology Lab Private Ltd13,649$139.0K0.02%+13,649New
Jump Financial, LLC13,400$137.0K0.01%+13,400New
OneAscent Wealth Management LLC13,172$134.0K0.07%+13,172New
Voya Investment Management LLC12,538$128.0K0.00%00.0%Unchanged
Invesco Ltd.12,499$127.0K0.00%+407+3.4%Added
Veritable, L.P.11,908$122.0K0.00%00.0%Unchanged
Prospera Financial Services Inc11,669$119.0K0.00%+11,669New
Cetera Advisors LLC11,194$114.0K0.00%+11,194New
ProShare Advisors LLC10,955$112.0K0.00%−2,642−19.4%Reduced
Bradley Foster & Sargent Inc11,000$112.0K0.00%00.0%Unchanged
OneAscent Financial Services LLC10,557$108.0K0.08%+10,557New
Zuckerman Investment Group, LLC10,479$107.0K0.02%00.0%Unchanged
Virtus ETF Advisers LLC8,515$87.0K0.04%−510−5.7%Reduced
Legal & General Group Plc7,902$81.0K0.00%00.0%Unchanged
Barclays PLC5,512$56.0K0.00%+5,512New
Tower Research Capital LLC (TRC)4,711$48.0K0.00%+3,391+256.9%Added
Ensign Peak Advisors, Inc4,370$45.0K0.00%00.0%Unchanged
Amalgamated Bank4,137$42.0K0.00%+4,137New
Amalgamated Financial Corp.4,137$42.0K0.00%+4,137New
Wells Fargo & Company2,969$31.0K0.00%−13,129−81.6%Reduced
Ameritas Investment Partners, Inc.2,483$25.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,443$24.9K0.00%−6,340−72.2%Reduced
Royal Bank of Canada2,047$21.0K0.00%−4,620−69.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)1,573$16.0K0.00%+1,573New
Point72 Hong Kong Ltd1,284$13.0K0.00%−281−18.0%Reduced
Macquarie Group Ltd1,239$13.0K0.00%00.0%Unchanged
Quantbot Technologies LP1,100$11.0K0.00%+700+175.0%Added
Nisa Investment Advisors, LLC710$7.00K0.00%−3,090−81.3%Reduced
Rockefeller Capital Management L.P.468$4.00K0.00%+42+9.9%Added
US Bancorp268$3.00K0.00%−481−64.2%Reduced
Signaturefd, LLC299$3.00K0.00%−108−26.5%Reduced
Group One Trading, L.P.309$3.00K0.00%+309New
Daiwa Securities Group Inc.131$1.00K0.00%00.0%Unchanged
Bessemer Group Inc62$1.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC126$1.00K0.00%+100+384.6%Added