Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 104
- −4 vs. Q3 2022
- Shares held
- 45.4M
- +3.28M (+7.8%) vs. Q3 2022
- Total value
- $108.1M
- +$12.4M (+13.0%) vs. Q3 2022
- New holders
- 18
- 26 more added
- Sold out
- 22
- 41 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Blackstone Group Inc. | 4,894,109 | $11.6M | 0.04% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 3,518,062 | $8.37M | 0.17% | 00.0% | Unchanged |
| BlackRock Inc. | 2,971,762 | $7.07M | 0.00% | −272,440−8.4% | Reduced |
| Kingdon Capital Management, L.L.C. | 2,855,989 | $6.80M | 1.76% | +1,700,000+147.1% | Added |
| PFM Health Sciences, LP | 2,777,467 | $6.61M | 0.28% | −681,058−19.7% | Reduced |
| Adage Capital Partners GP, L.L.C. | 2,256,041 | $5.37M | 0.01% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 1,830,315 | $4.36M | 0.03% | +1,830,315 | New |
| Vanguard Group Inc | 1,786,296 | $4.25M | 0.00% | −18,057−1.0% | Reduced |
| Verition Fund Management LLC | 1,670,371 | $3.98M | 0.08% | +766,063+84.7% | Added |
| EcoR1 Capital, LLC | 1,585,324 | $3.77M | 0.11% | +89,000+5.9% | Added |
| Bank of America Corp | 1,514,921 | $3.61M | 0.00% | +1,481,427+4,423.0% | Added |
| Vida Ventures Advisors, LLC | 1,469,665 | $3.50M | 4.70% | −1,469,664−50.0% | Reduced |
| Acadian Asset Management LLC | 1,353,530 | $3.22M | 0.02% | +331,869+32.5% | Added |
| Artal Group S.A. | 1,200,000 | $2.86M | 0.16% | 00.0% | Unchanged |
| 72 Investment Holdings, LLC | 988,995 | $2.35M | 1.08% | 00.0% | Unchanged |
| State Street Corp | 885,793 | $2.11M | 0.00% | +10,441+1.2% | Added |
| Octagon Capital Advisors LP | 800,000 | $1.90M | 0.30% | +800,000 | New |
| Harvard Management Co Inc | 778,517 | $1.85M | 0.23% | 00.0% | Unchanged |
| Citadel Advisors LLC | 755,330 | $1.80M | 0.00% | −325,769−30.1% | Reduced |
| Goldman Sachs Group Inc | 719,452 | $1.71M | 0.00% | −403,151−35.9% | Reduced |
| Geode Capital Management, LLC | 693,582 | $1.65M | 0.00% | +58,866+9.3% | Added |
| Ally Bridge Group (NY) LLC | 630,584 | $1.50M | 1.46% | +630,584 | New |
| MPM Oncology Impact Management LP | 610,000 | $1.45M | 0.38% | +610,000 | New |
| D. E. Shaw & Co., Inc. | 574,426 | $1.37M | 0.00% | +290,367+102.2% | Added |
| Two Sigma Advisers, LP | 447,700 | $1.07M | 0.00% | −56,100−11.1% | Reduced |
| CIBC Asset Management Inc | 379,637 | $903.5K | 0.00% | +379,637 | New |
| Federated Hermes, Inc. | 368,430 | $876.9K | 0.00% | +284,953+341.4% | Added |
| Renaissance Technologies LLC | 364,000 | $866.0K | 0.00% | −85,116−19.0% | Reduced |
| Northern Trust Corp | 351,871 | $837.5K | 0.00% | −18,723−5.1% | Reduced |
| Man Group plc | 306,661 | $729.9K | 0.00% | +67,202+28.1% | Added |
| Two Sigma Investments, LP | 278,772 | $663.5K | 0.00% | −163,215−36.9% | Reduced |
| Jacobs Levy Equity Management, Inc | 252,017 | $599.8K | 0.00% | −15,029−5.6% | Reduced |
| Laurion Capital Management LP | 196,669 | $468.1K | 0.01% | −1,429−0.7% | Reduced |
| Nuveen Asset Management, LLC | 191,561 | $455.0K | 0.00% | −5,080−2.6% | Reduced |
| Morgan Stanley | 182,057 | $433.3K | 0.00% | −92,816−33.8% | Reduced |
| Millennium Management LLC | 167,067 | $398.0K | 0.00% | −814,871−83.0% | Reduced |
| AQR Capital Management LLC | 160,529 | $382.1K | 0.00% | −91,223−36.2% | Reduced |
| Ikarian Capital, LLC | 150,000 | $357.0K | 0.15% | +150,000 | New |
| XTX Topco Ltd | 148,001 | $352.2K | 0.07% | +14,114+10.5% | Added |
| Los Angeles Capital Management LLC | 132,325 | $314.9K | 0.00% | +26,210+24.7% | Added |
| Bank of New York Mellon Corp | 118,790 | $282.7K | 0.00% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 117,292 | $279.0K | 0.00% | +76,245+185.8% | Added |
| Raymond James & Associates | 115,540 | $275.0K | 0.00% | −2,000−1.7% | Reduced |
| Bridgeway Capital Management, LLC | 113,600 | $270.4K | 0.01% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 110,363 | $262.7K | 0.00% | +26,178+31.1% | Added |
| HRT Financial LP | 105,846 | $251.0K | 0.00% | −96,058−47.6% | Reduced |
| Point72 Asset Management, L.P. | 100,000 | $238.0K | 0.00% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 98,409 | $234.2K | 0.08% | −1,591−1.6% | Reduced |
| Alliancebernstein L.P. | 80,700 | $192.1K | 0.00% | +17,100+26.9% | Added |
| Tekla Capital Management LLC | 75,000 | $178.5K | 0.01% | 00.0% | Unchanged |
| Cornercap Investment Counsel Inc | 72,975 | $173.7K | 0.03% | +230+0.3% | Added |
| Schonfeld Strategic Advisors LLC | 67,900 | $161.6K | 0.00% | −44,100−39.4% | Reduced |
| Susquehanna Fundamental Investments, LLC | 62,252 | $148.2K | 0.00% | −10,759−14.7% | Reduced |
| Jane Street Group, LLC | 57,774 | $137.5K | 0.00% | −45,624−44.1% | Reduced |
| Rhumbline Advisers | 55,450 | $132.0K | 0.00% | +263+0.5% | Added |
| Ameriprise Financial Inc | 54,698 | $130.0K | 0.00% | +100.0% | Added |
| Public Employees Retirement System of Ohio | 50,286 | $120.0K | 0.00% | −11,414−18.5% | Reduced |
| Price T Rowe Associates Inc | 47,933 | $114.0K | 0.00% | +12,324+34.6% | Added |
| Walleye Capital LLC | 43,745 | $104.1K | 0.00% | +17,006+63.6% | Added |
| Occudo Quantitative Strategies LP | 43,710 | $104.0K | 0.01% | −62,791−59.0% | Reduced |
| ExodusPoint Capital Management, LP | 42,360 | $101.0K | 0.00% | −21,849−34.0% | Reduced |
| Alta Wealth Advisors LLC | 31,028 | $73.8K | 0.05% | 00.0% | Unchanged |
| Thrivent Financial for Lutherans | 27,223 | $66.0K | 0.00% | +27,223 | New |
| Algert Global LLC | 26,830 | $63.9K | 0.00% | +26,830 | New |
| Atom Investors LP | 26,597 | $63.3K | 0.03% | +26,597 | New |
| Tower Research Capital LLC (TRC) | 26,601 | $63.0K | 0.00% | +9,559+56.1% | Added |
| New York State Common Retirement Fund | 26,332 | $62.7K | 0.00% | −73−0.3% | Reduced |
| Squarepoint Ops LLC | 25,618 | $61.0K | 0.00% | −151,588−85.5% | Reduced |
| Boothbay Fund Management, LLC | 25,560 | $60.8K | 0.00% | +25,560 | New |
| Tri Locum Partners LP | 24,147 | $57.0K | 0.03% | +24,147 | New |
| JPMorgan Chase & Co | 22,880 | $54.0K | 0.00% | −757−3.2% | Reduced |
| State Board of Administration of Florida Retirement System | 20,871 | $49.7K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 20,205 | $48.1K | 0.00% | −14,557−41.9% | Reduced |
| Panagora Asset Management Inc | 18,854 | $44.9K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 18,800 | $44.7K | 0.00% | +18,800 | New |
| American International Group, Inc. | 18,531 | $44.1K | 0.00% | +570+3.2% | Added |
| Voya Investment Management LLC | 18,069 | $43.0K | 0.00% | +18,069 | New |
| Cubist Systematic Strategies, LLC | 17,920 | $42.6K | 0.00% | −99,551−84.7% | Reduced |
| Mariner, LLC | 17,693 | $42.0K | 0.00% | +4,398+33.1% | Added |
| Allspring Global Investments Holdings, LLC | 16,175 | $38.5K | 0.00% | +16,175 | New |
| California State Teachers Retirement System | 15,639 | $37.2K | 0.00% | −30,632−66.2% | Reduced |
| Deutsche Bank AG | 13,964 | $33.2K | 0.00% | +253+1.8% | Added |
| SG Americas Securities, LLC | 13,739 | $33.0K | 0.00% | −4,078−22.9% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 13,865 | $33.0K | 0.00% | −54,642−79.8% | Reduced |
| Cetera Advisors LLC | 11,194 | $26.6K | 0.00% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 11,103 | $26.4K | 0.00% | +11,103 | New |
| Invesco Ltd. | 10,640 | $25.3K | 0.00% | −2,253−17.5% | Reduced |
| Quantum Private Wealth, LLC | 10,640 | $25.3K | 0.02% | −4,477−29.6% | Reduced |
| Barclays PLC | 10,539 | $25.1K | 0.00% | +8,935+557.0% | Added |
| Zuckerman Investment Group, LLC | 10,479 | $24.9K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 10,255 | $24.4K | 0.00% | +10,255 | New |
| Amalgamated Bank | 4,688 | $11.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 4,780 | $11.0K | 0.00% | +4,225+761.3% | Added |
| FMR LLC | 4,507 | $10.7K | 0.00% | −445,518−99.0% | Reduced |
| Legal & General Group Plc | 4,438 | $10.5K | 0.00% | −8,298−65.2% | Reduced |
| Ameritas Investment Partners, Inc. | 2,483 | $10.2K | 0.00% | 00.0% | Unchanged |
| Point72 Middle East FZE | 2,269 | $5.40K | 0.00% | +2,269 | New |
| Citigroup Inc | 2,056 | $4.89K | 0.00% | −7,422−78.3% | Reduced |
| Cutler Group LP | 1,700 | $4.00K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 1,222 | $2.00K | 0.00% | −11,620−90.5% | Reduced |