Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 162
- +28 vs. Q3 2024
- Shares held
- 21.7M
- +2.85M (+15.1%) vs. Q3 2024
- Total value
- $1.67B
- +$580.5M (+53.2%) vs. Q3 2024
- New holders
- 38
- 56 more added
- Sold out
- 10
- 52 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cormorant Asset Management, LP | 1,693,219 | $130.3M | 7.16% | +823,219+94.6% | Added |
| BlackRock, Inc. | 1,462,445 | $112.5M | 0.00% | +160,010+12.3% | Added |
| Perceptive Advisors LLC | 1,329,735 | $102.3M | 2.85% | +165,700+14.2% | Added |
| Price T Rowe Associates Inc | 1,208,522 | $93.0M | 0.01% | +88,442+7.9% | Added |
| Morgan Stanley | 1,163,526 | $89.5M | 0.01% | +1,083,026+1,345.4% | Added |
| Vanguard Group Inc | 1,063,639 | $81.9M | 0.00% | +24,645+2.4% | Added |
| Capital Research Global Investors | 993,569 | $76.5M | 0.02% | −3,525−0.4% | Reduced |
| VR Adviser, LLC | 989,985 | $76.2M | 5.23% | +283,854+40.2% | Added |
| Janus Henderson Group PLC | 929,523 | $71.6M | 0.04% | +405,957+77.5% | Added |
| State Street Corp | 768,655 | $59.2M | 0.00% | −20,969−2.7% | Reduced |
| Ra Capital Management, L.P. | 761,955 | $58.6M | 0.78% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 605,010 | $46.6M | 0.08% | −249,073−29.2% | Reduced |
| Assenagon Asset Management S.A. | 559,082 | $43.0M | 0.08% | +548,986+5,437.7% | Added |
| Point72 Asset Management, L.P. | 521,273 | $40.1M | 0.11% | −511,971−49.5% | Reduced |
| Verition Fund Management LLC | 464,508 | $35.7M | 0.18% | −94,643−16.9% | Reduced |
| Geode Capital Management, LLC | 406,711 | $31.3M | 0.00% | +7,873+2.0% | Added |
| Franklin Resources Inc | 389,835 | $30.0M | 0.01% | −55,398−12.4% | Reduced |
| CIBC Asset Management Inc | 366,756 | $28.2M | 0.09% | +117,817+47.3% | Added |
| Baker Bros. Advisors LP | 331,533 | $25.5M | 0.27% | +8,428+2.6% | Added |
| Nuveen Asset Management, LLC | 306,911 | $23.6M | 0.01% | +2,084+0.7% | Added |
| Kingdon Capital Management, L.L.C. | 303,000 | $23.3M | 3.99% | −65,000−17.7% | Reduced |
| Velan Capital Investment Management LP | 300,000 | $23.1M | 19.92% | −50,666−14.4% | Reduced |
| Goldman Sachs Group Inc | 279,395 | $21.5M | 0.00% | −225−0.1% | Reduced |
| Soleus Capital Management, L.P. | 243,540 | $18.7M | 1.42% | −15,858−6.1% | Reduced |
| Alyeska Investment Group, L.P. | 226,788 | $17.5M | 0.07% | +226,788 | New |
| FMR LLC | 188,367 | $14.5M | 0.00% | −85,528−31.2% | Reduced |
| 5AM Venture Management, LLC | 170,000 | $13.1M | 3.12% | −170,000−50.0% | Reduced |
| Northern Trust Corp | 167,590 | $12.9M | 0.00% | +15,323+10.1% | Added |
| Driehaus Capital Management LLC | 164,912 | $12.7M | 0.10% | −1,144−0.7% | Reduced |
| Susquehanna International Group, LLP | 157,925 | $12.2M | 0.02% | +128,931+444.7% | Added |
| Millennium Management LLC | 150,892 | $11.6M | 0.01% | +146,723+3,519.4% | Added |
| Charles Schwab Investment Management Inc | 142,892 | $11.0M | 0.00% | +5,840+4.3% | Added |
| StemPoint Capital LP | 134,178 | $10.3M | 2.59% | −39,856−22.9% | Reduced |
| UBS Group AG | 120,267 | $9.26M | 0.00% | +90,717+307.0% | Added |
| PFM Health Sciences, LP | 119,509 | $9.20M | 0.70% | −63,583−34.7% | Reduced |
| Norges Bank | 118,900 | $9.15M | 0.00% | +113,900+2,278.0% | Added |
| Candriam Luxembourg S.C.A. | 117,970 | $9.08M | 0.05% | −44,061−27.2% | Reduced |
| Voloridge Investment Management, LLC | 116,062 | $8.93M | 0.03% | +40,875+54.4% | Added |
| Polar Asset Management Partners Inc. | 98,617 | $7.59M | 0.11% | +98,617 | New |
| Citigroup Inc | 95,047 | $7.31M | 0.01% | +11,697+14.0% | Added |
| Citadel Advisors LLC | 93,190 | $7.17M | 0.01% | +45,156+94.0% | Added |
| Sphera Funds Management Ltd. | 91,583 | $7.05M | 1.30% | −60,724−39.9% | Reduced |
| Walleye Capital LLC | 89,613 | $6.90M | 0.07% | +34,000+61.1% | Added |
| Invesco Ltd. | 86,983 | $6.69M | 0.00% | −20,730−19.2% | Reduced |
| Alliancebernstein L.P. | 78,627 | $6.05M | 0.00% | +60,587+335.8% | Added |
| Silverarc Capital Management, LLC | 72,516 | $5.58M | 1.25% | +5,471+8.2% | Added |
| Acuta Capital Partners, LLC | 67,500 | $5.19M | 5.23% | +10,000+17.4% | Added |
| 72 Investment Holdings, LLC | 65,933 | $5.07M | 10.33% | 00.0% | Unchanged |
| Wellington Management Group LLP | 63,934 | $4.92M | 0.00% | −155,973−70.9% | Reduced |
| Marshall Wace, LLP | 58,305 | $4.49M | 0.01% | −111,790−65.7% | Reduced |
| TD Asset Management Inc | 52,898 | $4.07M | 0.00% | +9,000+20.5% | Added |
| D. E. Shaw & Co., Inc. | 47,993 | $3.69M | 0.00% | +1,629+3.5% | Added |
| Bank of New York Mellon Corp | 46,856 | $3.61M | 0.00% | −1,351−2.8% | Reduced |
| First Turn Management, LLC | 45,536 | $3.50M | 0.63% | +45,536 | New |
| Pictet Asset Management Holding SA | 45,427 | $3.50M | 0.00% | +45,427 | New |
| Ally Bridge Group (NY) LLC | 44,982 | $3.46M | 2.97% | −28,203−38.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 43,100 | $3.32M | 0.02% | +14,649+51.5% | Added |
| Simplify Asset Management Inc. | 43,085 | $3.32M | 0.23% | +43,085 | New |
| Jacobs Levy Equity Management, Inc | 39,999 | $3.08M | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 38,483 | $2.96M | 0.00% | +3,344+9.5% | Added |
| Barclays PLC | 37,288 | $2.87M | 0.00% | +158+0.4% | Added |
| Tri Locum Partners LP | 37,269 | $2.87M | 0.59% | +37,269 | New |
| Jane Street Group, LLC | 37,144 | $2.86M | 0.00% | −1,401−3.6% | Reduced |
| Rafferty Asset Management, LLC | 33,629 | $2.59M | 0.01% | −1,730−4.9% | Reduced |
| Qube Research & Technologies Ltd | 31,999 | $2.46M | 0.00% | −12,704−28.4% | Reduced |
| Moody Aldrich Partners LLC | 30,677 | $2.36M | 0.44% | −928−2.9% | Reduced |
| Ensign Peak Advisors, Inc | 27,650 | $2.13M | 0.00% | +27,650 | New |
| UBS Oconnor LLC | 26,503 | $2.04M | 0.05% | −11,987−31.1% | Reduced |
| Swiss National Bank | 26,100 | $2.01M | 0.00% | +1,000+4.0% | Added |
| Rhumbline Advisers | 22,769 | $1.75M | 0.00% | −347−1.5% | Reduced |
| Two Sigma Investments, LP | 20,066 | $1.54M | 0.00% | −2,700−11.9% | Reduced |
| UBS Asset Management Americas Inc | 18,615 | $1.43M | 0.00% | +2,747+17.3% | Added |
| PCG Wealth Advisors, LLC | 17,282 | $1.33M | 0.49% | −77−0.4% | Reduced |
| Simplex Trading, LLC | 16,854 | $1.30M | 0.04% | +4,436+35.7% | Added |
| American Century Companies Inc | 15,594 | $1.20M | 0.00% | +5,281+51.2% | Added |
| Deutsche Bank AG | 15,324 | $1.18M | 0.00% | +5,009+48.6% | Added |
| Alps Advisors Inc | 15,066 | $1.16M | 0.01% | +1,637+12.2% | Added |
| Legal & General Group Plc | 14,439 | $1.11M | 0.00% | +610+4.4% | Added |
| California State Teachers Retirement System | 12,726 | $979.4K | 0.00% | +275+2.2% | Added |
| J. Goldman & Co LP | 11,634 | $895.4K | 0.03% | +11,634 | New |
| Jump Financial, LLC | 11,188 | $861.0K | 0.02% | +11,188 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 11,135 | $856.0K | 0.00% | +258+2.4% | Added |
| HighVista Strategies LLC | 10,951 | $842.8K | 0.31% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 10,682 | $822.1K | 0.00% | −1,966−15.5% | Reduced |
| MetLife Investment Management | 10,675 | $821.5K | 0.00% | +544+5.4% | Added |
| Hussman Strategic Advisors, Inc. | 10,500 | $808.1K | 0.24% | −10,500−50.0% | Reduced |
| Woodline Partners LP | 9,948 | $765.6K | 0.01% | +9,948 | New |
| JPMorgan Chase & Co | 9,693 | $746.0K | 0.00% | +1,879+24.0% | Added |
| Fred Alger Management, LLC | 9,496 | $730.8K | 0.00% | −927−8.9% | Reduced |
| Trexquant Investment LP | 9,115 | $701.5K | 0.01% | −6,317−40.9% | Reduced |
| Wells Fargo & Company | 8,612 | $662.8K | 0.00% | +2,746+46.8% | Added |
| Corebridge Financial, Inc. | 8,574 | $659.9K | 0.00% | −646−7.0% | Reduced |
| Nicholas Investment Partners, LP | 8,481 | $652.7K | 0.06% | +8,481 | New |
| Ellsworth Advisors, LLC | 8,150 | $627.2K | 0.16% | +8,150 | New |
| New York State Common Retirement Fund | 7,847 | $603.9K | 0.00% | +847+12.1% | Added |
| Squarepoint Ops LLC | 7,782 | $598.9K | 0.00% | −6,876−46.9% | Reduced |
| AQR Capital Management LLC | 6,704 | $515.9K | 0.00% | −18,564−73.5% | Reduced |
| Profund Advisors LLC | 6,559 | $504.8K | 0.02% | −488−6.9% | Reduced |
| Intech Investment Management LLC | 6,338 | $487.8K | 0.00% | +2,567+68.1% | Added |
| State Board of Administration of Florida Retirement System | 6,040 | $464.8K | 0.00% | −230−3.7% | Reduced |