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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
−6 vs. Q1 2022
Shares held
43.1M
−2.24M (−4.9%) vs. Q1 2022
Total value
$105.5M
−$357.7M (−77.2%) vs. Q1 2022
New holders
21
38 more added
Sold out
27
21 more reduced

2 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 95 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2022: $105.5M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2022.

Institutions holding PRAX in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State Street Corp5,098,669$12.5M0.00%+3,705,283+265.9%Added
Blackstone Group Inc.4,894,109$12.0M0.04%00.0%Unchanged
Eventide Asset Management, LLC3,518,062$8.62M0.18%−876,938−20.0%Reduced
PFM Health Sciences, LP3,297,347$8.08M0.32%+2,432,528+281.3%Added
BlackRock Inc.2,970,762$7.28M0.00%+441,001+17.4%Added
Vida Ventures Advisors, LLC2,939,329$7.20M6.08%00.0%Unchanged
Vanguard Group Inc2,541,298$6.23M0.00%−780,842−23.5%Reduced
Adage Capital Partners GP, L.L.C.1,756,041$4.30M0.01%+963,960+121.7%Added
Citadel Advisors LLC1,439,694$3.53M0.00%−110,612−7.1%Reduced
Artal Group S.A.1,200,000$2.94M0.16%00.0%Unchanged
Kingdon Capital Management, L.L.C.1,155,989$2.83M0.76%+741,500+178.9%Added
72 Investment Holdings, LLC988,995$2.42M3.74%00.0%Unchanged
Verition Fund Management LLC840,232$2.06M0.04%+603,858+255.5%Added
Acadian Asset Management LLC829,117$2.03M0.01%+829,117New
Harvard Management Co Inc778,517$1.91M0.22%00.0%Unchanged
Geode Capital Management, LLC636,907$1.56M0.00%+9,619+1.5%Added
Goldman Sachs Group Inc595,690$1.46M0.00%+456,140+326.9%Added
Morgan Stanley527,223$1.29M0.00%+455,125+631.3%Added
Laurion Capital Management LP486,669$1.19M0.05%−58,710−10.8%Reduced
FMR LLC483,019$1.18M0.00%−4,119,852−89.5%Reduced
Two Sigma Investments, LP403,632$989.0K0.00%+289,369+253.2%Added
Northern Trust Corp371,466$911.0K0.00%+53,855+17.0%Added
Bank of America Corp312,035$764.0K0.00%+205,245+192.2%Added
Woodline Partners LP308,746$756.0K0.01%00.0%Unchanged
Millennium Management LLC277,102$679.0K0.00%+199,232+255.9%Added
Charles Schwab Investment Management Inc258,316$633.0K0.00%+4,141+1.6%Added
Citigroup Inc243,569$597.0K0.00%+213,285+704.3%Added
Nuveen Asset Management, LLC241,242$591.0K0.00%+16,374+7.3%Added
Rafferty Asset Management, LLC229,840$563.0K0.01%+159,633+227.4%Added
Two Sigma Advisers, LP221,000$541.0K0.00%+163,700+285.7%Added
Renaissance Technologies LLC217,400$533.0K0.00%+145,600+202.8%Added
UBS Oconnor LLC215,776$529.0K0.01%+215,776New
Occudo Quantitative Strategies LP212,830$521.0K0.04%+212,830New
EcoR1 Capital, LLC210,100$515.0K0.02%+210,100New
Schonfeld Strategic Advisors LLC172,978$423.0K0.00%+172,978New
UBS Group AG156,707$384.0K0.00%+84,789+117.9%Added
Cubist Systematic Strategies, LLC119,875$294.0K0.00%+103,803+645.9%Added
Raymond James & Associates117,540$288.0K0.00%−794−0.7%Reduced
Los Angeles Capital Management LLC107,445$263.0K0.00%+107,445New
Bank of New York Mellon Corp103,744$254.0K0.00%−5,778−5.3%Reduced
ExodusPoint Capital Management, LP103,819$254.0K0.00%+103,819New
Point72 Asset Management, L.P.100,000$245.0K0.00%−1,228,943−92.5%Reduced
Jane Street Group, LLC96,930$238.0K0.00%+96,930New
D. E. Shaw & Co., Inc.96,923$237.0K0.00%+96,923New
Swiss National Bank85,800$210.0K0.00%+32,700+61.6%Added
Endurant Capital Management LP79,097$194.0K0.07%−355−0.4%Reduced
Tekla Capital Management LLC75,000$184.0K0.01%00.0%Unchanged
Susquehanna International Group, LLP74,071$181.0K0.00%+55,884+307.3%Added
XTX Topco Ltd71,196$174.0K0.07%+71,196New
Graham Capital Management, L.P.54,016$132.0K0.01%+54,016New
Alliancebernstein L.P.53,300$131.0K0.00%−1,996,540−97.4%Reduced
State of Wisconsin Investment Board53,281$131.0K0.00%−22,519−29.7%Reduced
SG Americas Securities, LLC49,223$121.0K0.00%+49,223New
Rhumbline Advisers48,464$119.0K0.00%+7,088+17.1%Added
California State Teachers Retirement System46,738$115.0K0.00%+13,029+38.7%Added
Jump Financial, LLC42,900$105.0K0.00%+29,500+220.1%Added
Price T Rowe Associates Inc40,964$100.0K0.00%+13,437+48.8%Added
PEAK6 Investments LLC74,468$85.6K0.00%+74,468New
Alta Wealth Advisors LLC31,028$76.0K0.05%00.0%Unchanged
New York State Common Retirement Fund26,231$64.0K0.00%+4,520+20.8%Added
E Fund Management Co., Ltd.26,064$64.0K0.01%+26,064New
Simplex Trading, LLC24,788$60.0K0.00%+24,788New
JPMorgan Chase & Co22,481$55.0K0.00%−11,314−33.5%Reduced
Squarepoint Ops LLC21,560$53.0K0.00%+21,560New
State Board of Administration of Florida Retirement System20,871$51.0K0.00%+100.0%Added
Quantbot Technologies LP21,050$51.0K0.00%+19,950+1,813.6%Added
Quantum Private Wealth, LLC20,384$49.0K0.03%+223+1.1%Added
Cornercap Investment Counsel Inc20,008$49.0K0.01%+20,008New
Deutsche Bank AG18,946$47.0K0.00%−2,297−10.8%Reduced
American International Group, Inc.17,707$43.0K0.00%+1,168+7.1%Added
AQR Capital Management LLC17,396$43.0K0.00%+17,396New
Credit Suisse AG15,301$37.0K0.00%−262−1.7%Reduced
Tower Research Capital LLC (TRC)13,882$34.0K0.00%+9,171+194.7%Added
Invesco Ltd.12,989$32.0K0.00%+490+3.9%Added
Legal & General Group Plc12,736$31.0K0.00%+4,834+61.2%Added
Cetera Advisors LLC11,194$27.0K0.00%00.0%Unchanged
Zuckerman Investment Group, LLC10,479$26.0K0.00%00.0%Unchanged
Amalgamated Bank4,679$11.0K0.00%+542+13.1%Added
Group One Trading, L.P.4,108$10.0K0.00%+3,799+1,229.4%Added
Wells Fargo & Company2,958$7.00K0.00%−11−0.4%Reduced
Ameritas Investment Partners, Inc.2,483$6.00K0.00%00.0%Unchanged
Barclays PLC1,899$5.00K0.00%−3,613−65.5%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)1,573$4.00K0.00%00.0%Unchanged
Cutler Group LP1,700$4.00K0.00%+1,700New
Macquarie Group Ltd1,239$3.00K0.00%00.0%Unchanged
Captrust Financial Advisors1,345$3.00K0.00%+1,345New
Royal Bank of Canada213$1.00K0.00%−1,834−89.6%Reduced
Nisa Investment Advisors, LLC550$1.00K0.00%−160−22.5%Reduced
Rockefeller Capital Management L.P.666$1.00K0.00%+198+42.3%Added
US Bancorp205$1.00K0.00%−63−23.5%Reduced
Signaturefd, LLC207$1.00K0.00%−92−30.8%Reduced
Quadrant Capital Group LLC408$1.00K0.00%+408New
Daiwa Securities Group Inc.131$00.00%00.0%Unchanged
Lindbrook Capital, LLC115$00.00%−11−8.7%Reduced
Newbridge Financial Services Group, Inc.23$00.00%00.0%Unchanged
Janus Henderson Group PLC0$00.00%−3,333,943−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−2,150,000−100.0%Sold out
Cormorant Asset Management, LP0$00.00%−752,406−100.0%Sold out
Franklin Resources Inc0$00.00%−274,812−100.0%Sold out
Novo Holdings A/S0$00.00%−250,000−100.0%Sold out