Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 100
- +8 vs. Q3 2021
- Shares held
- 43.8M
- +1.17M (+2.8%) vs. Q3 2021
- Total value
- $863.1M
- +$74.7M (+9.5%) vs. Q3 2021
- New holders
- 16
- 45 more added
- Sold out
- 8
- 16 more reduced
1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Blackstone Group Inc. | 4,894,109 | $96.4M | 0.24% | −446,546−8.4% | Reduced |
| FMR LLC | 4,576,229 | $90.2M | 0.01% | −80,600−1.7% | Reduced |
| Eventide Asset Management, LLC | 3,810,599 | $75.1M | 0.96% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 3,342,569 | $65.9M | 0.03% | +63,404+1.9% | Added |
| Vanguard Group Inc | 3,292,443 | $64.9M | 0.00% | +84,518+2.6% | Added |
| Vida Ventures Advisors, LLC | 2,939,329 | $57.9M | 21.66% | 00.0% | Unchanged |
| BlackRock Inc. | 2,496,696 | $49.2M | 0.00% | +352,027+16.4% | Added |
| Alliancebernstein L.P. | 1,873,510 | $36.9M | 0.01% | +228,502+13.9% | Added |
| Avoro Capital Advisors LLC | 1,780,000 | $35.1M | 0.60% | +180,000+11.3% | Added |
| Citadel Advisors LLC | 1,623,523 | $32.0M | 0.03% | −15,207−0.9% | Reduced |
| Point72 Asset Management, L.P. | 1,446,393 | $28.5M | 0.13% | +309,398+27.2% | Added |
| State Street Corp | 1,267,815 | $25.0M | 0.00% | +759,911+149.6% | Added |
| Artal Group S.A. | 1,200,000 | $23.6M | 0.69% | 00.0% | Unchanged |
| 72 Investment Holdings, LLC | 988,995 | $19.5M | 17.29% | 00.0% | Unchanged |
| Harvard Management Co Inc | 778,517 | $15.3M | 1.44% | 00.0% | Unchanged |
| Cormorant Asset Management, LP | 752,406 | $14.8M | 0.88% | −271,755−26.5% | Reduced |
| Adage Capital Partners GP, L.L.C. | 692,081 | $13.6M | 0.02% | +80,000+13.1% | Added |
| PFM Health Sciences, LP | 635,904 | $12.5M | 0.44% | +180,530+39.6% | Added |
| Geode Capital Management, LLC | 597,383 | $11.8M | 0.00% | +13,129+2.2% | Added |
| Laurion Capital Management LP | 552,579 | $10.9M | 0.19% | +58,000+11.7% | Added |
| Kingdon Capital Management, L.L.C. | 414,489 | $8.16M | 1.22% | 00.0% | Unchanged |
| Northern Trust Corp | 314,320 | $6.19M | 0.00% | +16,096+5.4% | Added |
| Woodline Partners LP | 308,746 | $6.08M | 0.09% | 00.0% | Unchanged |
| Franklin Resources Inc | 274,812 | $5.41M | 0.00% | +60.0% | Added |
| Novo Holdings A/S | 250,000 | $4.92M | 0.23% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 247,761 | $4.88M | 0.00% | +9,846+4.1% | Added |
| Nuveen Asset Management, LLC | 218,615 | $4.31M | 0.00% | +93,396+74.6% | Added |
| Verition Fund Management LLC | 212,293 | $4.18M | 0.05% | −199,999−48.5% | Reduced |
| Jennison Associates LLC | 193,834 | $3.82M | 0.00% | −1,588−0.8% | Reduced |
| Two Sigma Investments, LP | 152,161 | $3.00M | 0.01% | +25,553+20.2% | Added |
| Raymond James & Associates | 118,294 | $2.33M | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 107,582 | $2.12M | 0.00% | +3,994+3.9% | Added |
| Bank of America Corp | 92,336 | $1.82M | 0.00% | +67,315+269.0% | Added |
| Endurant Capital Management LP | 89,561 | $1.76M | 0.48% | −64,038−41.7% | Reduced |
| UBS Group AG | 86,105 | $1.70M | 0.00% | +86,050+156,454.5% | Added |
| Citigroup Inc | 80,665 | $1.59M | 0.00% | +42,550+111.6% | Added |
| Goldman Sachs Group Inc | 75,886 | $1.50M | 0.00% | −32,993−30.3% | Reduced |
| Tekla Capital Management LLC | 75,000 | $1.48M | 0.05% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 67,491 | $1.33M | 0.01% | +67,491 | New |
| Two Sigma Advisers, LP | 62,600 | $1.23M | 0.00% | +32,600+108.7% | Added |
| Alps Advisors Inc | 51,907 | $1.02M | 0.01% | −3,136−5.7% | Reduced |
| Swiss National Bank | 49,200 | $969.0K | 0.00% | +1,200+2.5% | Added |
| Rhumbline Advisers | 37,909 | $747.0K | 0.00% | +2,271+6.4% | Added |
| California State Teachers Retirement System | 37,081 | $730.0K | 0.00% | +1,723+4.9% | Added |
| Values First Advisors, Inc. | 35,571 | $701.0K | 0.42% | +9,094+34.3% | Added |
| Millennium Management LLC | 34,236 | $674.0K | 0.00% | −77,745−69.4% | Reduced |
| State of Wisconsin Investment Board | 31,500 | $621.0K | 0.00% | 00.0% | Unchanged |
| Alta Wealth Advisors LLC | 31,028 | $611.0K | 0.38% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 28,773 | $568.0K | 0.00% | +5,747+25.0% | Added |
| Price T Rowe Associates Inc | 26,736 | $527.0K | 0.00% | +5,976+28.8% | Added |
| Susquehanna International Group, LLP | 26,652 | $525.0K | 0.00% | +26,652 | New |
| Deutsche Bank AG | 23,181 | $457.0K | 0.00% | +2,058+9.7% | Added |
| New York State Common Retirement Fund | 21,686 | $427.0K | 0.00% | +5,436+33.5% | Added |
| State Board of Administration of Florida Retirement System | 20,861 | $411.0K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 20,291 | $400.0K | 0.00% | +5,807+40.1% | Added |
| Quantum Private Wealth, LLC | 20,161 | $397.0K | 0.15% | +20,161 | New |
| Parametric Portfolio Associates LLC | 19,976 | $394.0K | 0.00% | +4,172+26.4% | Added |
| Susquehanna Fundamental Investments, LLC | 18,360 | $362.0K | 0.01% | +18,360 | New |
| Cna Financial Corp | 18,231 | $359.0K | 0.09% | +1,390+8.3% | Added |
| Manufacturers Life Insurance Company, The | 18,027 | $355.0K | 0.00% | +252+1.4% | Added |
| American International Group, Inc. | 17,704 | $349.0K | 0.00% | −27−0.2% | Reduced |
| Credit Suisse AG | 16,527 | $327.0K | 0.00% | +3,344+25.4% | Added |
| Wells Fargo & Company | 16,098 | $318.0K | 0.00% | +14,570+953.5% | Added |
| Marshall Wace, LLP | 16,087 | $316.0K | 0.00% | −185,224−92.0% | Reduced |
| Trexquant Investment LP | 15,986 | $315.0K | 0.02% | +15,986 | New |
| ProShare Advisors LLC | 13,597 | $267.0K | 0.00% | +13,597 | New |
| Renaissance Technologies LLC | 13,100 | $258.0K | 0.00% | +13,100 | New |
| MetLife Investment Management | 13,093 | $257.9K | 0.00% | +2,254+20.8% | Added |
| Voya Investment Management LLC | 12,538 | $247.0K | 0.00% | +580+4.9% | Added |
| Invesco Ltd. | 12,092 | $239.0K | 0.00% | +1,183+10.8% | Added |
| Veritable, L.P. | 11,908 | $235.0K | 0.00% | 00.0% | Unchanged |
| Bradley Foster & Sargent Inc | 11,000 | $217.0K | 0.00% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 10,725 | $211.0K | 0.03% | +10,725 | New |
| Zuckerman Investment Group, LLC | 10,479 | $206.0K | 0.03% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 9,635 | $190.0K | 0.00% | −9,848−50.5% | Reduced |
| Cubist Systematic Strategies, LLC | 9,599 | $189.0K | 0.00% | +2,189+29.5% | Added |
| Virtus ETF Advisers LLC | 9,025 | $178.0K | 0.07% | −1,235−12.0% | Reduced |
| Metropolitan Life Insurance Co | 8,783 | $173.0K | 0.00% | +485+5.8% | Added |
| Legal & General Group Plc | 7,902 | $156.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 6,667 | $132.0K | 0.00% | +3,058+84.7% | Added |
| Ensign Peak Advisors, Inc | 4,370 | $86.0K | 0.00% | +4,370 | New |
| Nisa Investment Advisors, LLC | 3,800 | $56.0K | 0.00% | +3,800 | New |
| Ameritas Investment Partners, Inc. | 2,483 | $49.0K | 0.00% | 00.0% | Unchanged |
| Point72 Hong Kong Ltd | 1,565 | $31.0K | 0.00% | +1,565 | New |
| Tower Research Capital LLC (TRC) | 1,320 | $26.0K | 0.00% | +179+15.7% | Added |
| Macquarie Group Ltd | 1,239 | $24.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 749 | $15.0K | 0.00% | +519+225.7% | Added |
| Rockefeller Capital Management L.P. | 426 | $8.00K | 0.00% | +26+6.5% | Added |
| Signaturefd, LLC | 407 | $8.00K | 0.00% | +266+188.7% | Added |
| Quantbot Technologies LP | 400 | $7.00K | 0.00% | +400 | New |
| Daiwa Securities Group Inc. | 131 | $3.00K | 0.00% | +131 | New |
| Simplex Trading, LLC | 135 | $2.00K | 0.00% | +135 | New |
| Parallel Advisors, LLC | 75 | $1.00K | 0.00% | −91−54.8% | Reduced |
| Quadrant Capital Group LLC | 49 | $1.00K | 0.00% | −75−60.5% | Reduced |
| Bessemer Group Inc | 62 | $1.00K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 53 | $1.00K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 26 | $1.00K | 0.00% | 00.0% | Unchanged |
| Tarbox Family Office, Inc. | 60 | $1.00K | 0.00% | +60 | New |
| Newbridge Financial Services Group, Inc. | 23 | $0 | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 22 | $0 | 0.00% | +22 | New |