Skip to main content

Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
80
+12 vs. Q1 2021
Shares held
41.2M
+4.54M (+12.4%) vs. Q1 2021
Total value
$751.0M
−$437.3M (−36.8%) vs. Q1 2021
New holders
24
38 more added
Sold out
12
10 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 80 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2021: $751.0M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2021.

Institutions holding PRAX in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Blackstone Group Inc.5,801,487$106.1M0.25%−2,700,000−31.8%Reduced
FMR LLC4,702,929$86.0M0.01%+413,704+9.6%Added
Eventide Asset Management, LLC3,787,053$67.7M0.91%+273,972+7.8%Added
Janus Henderson Group PLC2,978,485$54.4M0.02%+1,915,096+180.1%Added
Vida Ventures Advisors, LLC2,939,329$53.7M13.47%00.0%Unchanged
Vanguard Group Inc2,547,753$46.6M0.00%+1,532,184+150.9%Added
Citadel Advisors LLC1,858,913$34.0M0.04%+256,033+16.0%Added
Avoro Capital Advisors LLC1,600,000$29.2M0.51%+3,505+0.2%Added
BlackRock Inc.1,513,973$27.7M0.00%+305,922+25.3%Added
Alliancebernstein L.P.1,419,368$25.9M0.01%+527,815+59.2%Added
Artal Group S.A.1,200,000$21.9M0.50%+450,000+60.0%Added
Cormorant Asset Management, LP1,024,145$18.7M0.73%−50,000−4.7%Reduced
72 Investment Holdings, LLC988,995$18.1M28.49%00.0%Unchanged
Novo Holdings A/S910,450$16.6M0.74%−1,531,630−62.7%Reduced
Point72 Asset Management, L.P.786,995$14.4M0.07%+650,000+474.5%Added
Harvard Management Co Inc778,517$14.2M0.82%00.0%Unchanged
Adage Capital Partners GP, L.L.C.587,081$10.7M0.02%+175,000+42.5%Added
Laurion Capital Management LP493,658$9.02M0.14%+443,658+887.3%Added
PFM Health Sciences, LP455,374$8.32M0.27%+455,374New
Verition Fund Management LLC412,448$7.54M0.11%−62,008−13.1%Reduced
Woodline Partners LP356,440$6.52M0.12%+104,777+41.6%Added
State Street Corp351,313$6.42M0.00%−378,844−51.9%Reduced
Geode Capital Management, LLC344,017$6.29M0.00%+133,859+63.7%Added
Franklin Resources Inc274,806$5.02M0.00%+24,800+9.9%Added
Kingdon Capital Management, L.L.C.250,000$4.57M0.70%+250,000New
Northern Trust Corp223,186$4.08M0.00%+102,496+84.9%Added
Endurant Capital Management LP199,565$3.65M1.00%+199,565New
Jennison Associates LLC197,510$3.61M0.00%00.0%Unchanged
Marshall Wace, LLP188,836$3.45M0.02%+188,836New
Two Sigma Investments, LP184,292$3.37M0.01%+184,292New
Marshall Wace North America L.P.139,897$2.56M0.01%−178,069−56.0%Reduced
Nuveen Asset Management, LLC120,004$2.19M0.00%+63,439+112.2%Added
Charles Schwab Investment Management Inc119,719$2.19M0.00%+47,071+64.8%Added
Raymond James & Associates116,323$2.13M0.00%+116,323New
Morgan Stanley100,017$1.83M0.00%+95,608+2,168.5%Added
Monashee Investment Management LLC100,000$1.83M0.22%+100,000New
Goldman Sachs Group Inc86,386$1.58M0.00%−13,283−13.3%Reduced
Sphera Funds Management Ltd.75,600$1.38M0.13%+75,600New
Tekla Capital Management LLC75,000$1.37M0.04%00.0%Unchanged
Alyeska Investment Group, L.P.75,000$1.37M0.02%+75,000New
Bank of New York Mellon Corp68,931$1.26M0.00%+35,683+107.3%Added
Millennium Management LLC61,314$1.12M0.00%+35,625+138.7%Added
Alps Advisors Inc57,455$1.05M0.01%+57,455New
Swiss National Bank48,000$877.0K0.00%+48,000New
Cubist Systematic Strategies, LLC47,797$874.0K0.01%+44,612+1,400.7%Added
D. E. Shaw & Co., Inc.45,264$827.0K0.00%+45,264New
Voloridge Investment Management, LLC43,304$792.0K0.01%+43,304New
Renaissance Technologies LLC37,400$684.0K0.00%+37,400New
Citigroup Inc36,893$674.0K0.00%−9,794−21.0%Reduced
California State Teachers Retirement System33,632$615.0K0.00%+17,001+102.2%Added
State of Wisconsin Investment Board31,500$576.0K0.00%+31,500New
Alta Wealth Advisors LLC31,028$567.0K0.42%+31,028New
Rhumbline Advisers29,070$531.0K0.00%+18,481+174.5%Added
Two Sigma Advisers, LP24,100$441.0K0.00%+24,100New
New York State Common Retirement Fund20,989$384.0K0.00%+10,489+99.9%Added
Los Angeles Capital Management LLC17,600$322.0K0.00%−830−4.5%Reduced
Squarepoint Ops LLC17,427$319.0K0.00%+17,427New
Deutsche Bank AG16,964$310.0K0.00%+9,457+126.0%Added
JPMorgan Chase & Co16,400$300.0K0.00%+8,944+120.0%Added
Cna Financial Corp14,831$271.0K0.08%+4,900+49.3%Added
Manufacturers Life Insurance Company, The14,543$266.0K0.00%+8,184+128.7%Added
Bank of America Corp14,271$262.0K0.00%+1,803+14.5%Added
American International Group, Inc.13,666$250.0K0.00%+7,238+112.6%Added
Bradley Foster & Sargent Inc11,000$201.0K0.00%+4,000+57.1%Added
MetLife Investment Management10,839$198.1K0.00%+5,643+108.6%Added
Credit Suisse AG10,826$197.0K0.00%+10,826New
Virtus ETF Advisers LLC10,801$197.0K0.08%+10,801New
Tower Research Capital LLC (TRC)4,290$78.0K0.00%+3,249+312.1%Added
Legal & General Group Plc2,952$54.0K0.00%+1,802+156.7%Added
STRS Ohio2,700$49.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,912$35.0K0.00%+988+106.9%Added
Royal Bank of Canada1,673$31.0K0.00%+809+93.6%Added
O'Shaughnessy Asset Management, LLC1,004$18.0K0.00%+1,004New
Evolution Wealth Advisors, LLC642$12.0K0.00%+421+190.5%Added
Rockefeller Capital Management L.P.400$7.00K0.00%+400New
Wells Fargo & Company185$3.00K0.00%−1,633−89.8%Reduced
US Bancorp180$3.00K0.00%+180New
Bessemer Group Inc62$1.00K0.00%00.0%Unchanged
Parallel Advisors, LLC47$1.00K0.00%+47New
Newbridge Financial Services Group, Inc.23$00.00%00.0%Unchanged
Acuta Capital Partners, LLC0$00.00%−154,229−100.0%Sold out
Maven Securities LTD0$00.00%−48,693−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−37,594−100.0%Sold out
California Public Employees Retirement System0$00.00%−21,118−100.0%Sold out
First Midwest Bank Trust Division0$00.00%−6,930−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−3,631−100.0%Sold out
Pacer Advisors, Inc.0$00.00%−870−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−356−100.0%Sold out
Bank of Montreal0$00.00%−303−100.0%Sold out
Patriot Financial Group Insurance Agency, LLC0$00.00%−49−100.0%Sold out
Private Capital Group, LLC0$00.00%−24−100.0%Sold out
Captrust Financial Advisors0$00.00%−14−100.0%Sold out