Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 111
- +51 vs. Q4 2023
- Shares held
- 15.9M
- +7.90M (+98.6%) vs. Q4 2023
- Total value
- $971.3M
- +$792.7M (+443.9%) vs. Q4 2023
- New holders
- 58
- 30 more added
- Sold out
- 7
- 17 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Adage Capital Partners GP, L.L.C. | 1,393,028 | $85.0M | 0.16% | +654,362+88.6% | Added |
| Cormorant Asset Management, LP | 1,310,000 | $79.9M | 3.52% | +676,655+106.8% | Added |
| Point72 Asset Management, L.P. | 954,140 | $58.2M | 0.17% | +261,888+37.8% | Added |
| Ra Capital Management, L.P. | 828,380 | $50.5M | 0.64% | +828,380 | New |
| Perceptive Advisors LLC | 821,589 | $50.1M | 0.88% | +821,589 | New |
| Vanguard Group Inc | 744,069 | $45.4M | 0.00% | +373,131+100.6% | Added |
| VR Adviser, LLC | 706,126 | $43.1M | 2.05% | +352,500+99.7% | Added |
| Verition Fund Management LLC | 545,408 | $33.3M | 0.32% | −157,592−22.4% | Reduced |
| Price T Rowe Associates Inc | 535,999 | $32.7M | 0.00% | +535,999 | New |
| PFM Health Sciences, LP | 477,605 | $29.1M | 1.45% | −178,943−27.3% | Reduced |
| OrbiMed Advisors LLC | 460,512 | $28.1M | 0.55% | +460,512 | New |
| FMR LLC | 442,621 | $27.0M | 0.00% | +442,506+384,787.8% | Added |
| Velan Capital Investment Management LP | 350,666 | $21.4M | 11.57% | +5,000+1.4% | Added |
| Kingdon Capital Management, L.L.C. | 350,000 | $21.4M | 2.83% | +3,335+1.0% | Added |
| 5AM Venture Management, LLC | 340,000 | $20.7M | 4.65% | +340,000 | New |
| Janus Henderson Group PLC | 310,059 | $18.9M | 0.01% | +310,059 | New |
| Driehaus Capital Management LLC | 266,496 | $16.3M | 0.16% | +266,496 | New |
| Octagon Capital Advisors LP | 260,000 | $15.9M | 1.93% | +260,000 | New |
| Laurion Capital Management LP | 225,000 | $13.7M | 0.38% | +225,000 | New |
| BlackRock Inc. | 221,745 | $13.5M | 0.00% | +95,209+75.2% | Added |
| Vestal Point Capital, LP | 210,000 | $12.8M | 1.06% | +210,000 | New |
| CIBC Asset Management Inc | 192,304 | $11.7M | 0.04% | +18,436+10.6% | Added |
| Silverarc Capital Management, LLC | 190,556 | $11.6M | 3.26% | −93,285−32.9% | Reduced |
| Sphera Funds Management Ltd. | 177,139 | $10.8M | 1.75% | −151,847−46.2% | Reduced |
| Millennium Management LLC | 176,952 | $10.8M | 0.01% | +154,606+691.9% | Added |
| Ikarian Capital, LLC | 168,388 | $10.3M | 2.79% | −31,612−15.8% | Reduced |
| Acuta Capital Partners, LLC | 162,302 | $9.90M | 6.43% | −137,334−45.8% | Reduced |
| Ally Bridge Group (NY) LLC | 159,486 | $9.73M | 5.41% | +89,062+126.5% | Added |
| Logos Global Management LP | 150,000 | $9.15M | 0.96% | +150,000 | New |
| Franklin Resources Inc | 145,295 | $8.87M | 0.00% | +145,295 | New |
| Geode Capital Management, LLC | 134,717 | $8.22M | 0.00% | +41,759+44.9% | Added |
| Qube Research & Technologies Ltd | 132,942 | $8.11M | 0.01% | +107,838+429.6% | Added |
| Baker Bros. Advisors LP | 131,533 | $8.03M | 0.10% | 00.0% | Unchanged |
| Marshall Wace, LLP | 121,024 | $7.38M | 0.01% | +72,182+147.8% | Added |
| Tri Locum Partners LP | 106,494 | $6.50M | 2.25% | −142,267−57.2% | Reduced |
| Susquehanna International Group, LLP | 106,159 | $6.48M | 0.01% | +57,875+119.9% | Added |
| Morgan Stanley | 100,136 | $6.11M | 0.00% | +83,203+491.4% | Added |
| Goldman Sachs Group Inc | 98,635 | $6.02M | 0.00% | +98,635 | New |
| Invesco Ltd. | 95,181 | $5.81M | 0.00% | +95,181 | New |
| LMR Partners LLP | 94,332 | $5.76M | 0.15% | +94,332 | New |
| Hudson Bay Capital Management LP | 93,000 | $5.67M | 0.05% | +93,000 | New |
| Acadian Asset Management LLC | 82,254 | $5.02M | 0.02% | −15,795−16.1% | Reduced |
| Altium Capital Management LP | 78,100 | $4.77M | 2.13% | +78,100 | New |
| Assenagon Asset Management S.A. | 71,253 | $4.35M | 0.01% | +71,253 | New |
| 72 Investment Holdings, LLC | 65,933 | $4.02M | 6.00% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 51,548 | $3.15M | 0.01% | −14,940−22.5% | Reduced |
| JPMorgan Chase & Co | 51,372 | $3.13M | 0.00% | +51,355+302,088.2% | Added |
| Farallon Capital Management, L.L.C. | 50,000 | $3.05M | 0.02% | +50,000 | New |
| Jane Street Group, LLC | 47,066 | $2.87M | 0.00% | +36,490+345.0% | Added |
| Fred Alger Management, LLC | 47,041 | $2.87M | 0.01% | +47,041 | New |
| State Street Corp | 44,508 | $2.72M | 0.00% | +13,800+44.9% | Added |
| Boothbay Fund Management, LLC | 42,803 | $2.61M | 0.08% | −3,907−8.4% | Reduced |
| Superstring Capital Management LP | 40,119 | $2.45M | 1.62% | +40,119 | New |
| Wellington Management Group LLP | 39,565 | $2.41M | 0.00% | +39,565 | New |
| Soleus Capital Management, L.P. | 37,268 | $2.27M | 0.20% | +37,268 | New |
| TD Asset Management Inc | 35,000 | $2.14M | 0.00% | +35,000 | New |
| Atom Investors LP | 34,867 | $2.13M | 0.27% | +4,830+16.1% | Added |
| UBS Oconnor LLC | 34,729 | $2.12M | 0.06% | +12,451+55.9% | Added |
| Voloridge Investment Management, LLC | 27,667 | $1.69M | 0.01% | +27,667 | New |
| Northern Trust Corp | 27,279 | $1.66M | 0.00% | +7,915+40.9% | Added |
| Woodline Partners LP | 27,263 | $1.66M | 0.02% | +27,263 | New |
| StemPoint Capital LP | 26,893 | $1.64M | 0.44% | +26,893 | New |
| Citadel Advisors LLC | 26,008 | $1.59M | 0.00% | −30,471−54.0% | Reduced |
| Alyeska Investment Group, L.P. | 25,000 | $1.53M | 0.01% | +25,000 | New |
| Two Sigma Investments, LP | 23,372 | $1.43M | 0.00% | +13,946+148.0% | Added |
| Bridgeway Capital Management, LLC | 21,152 | $1.29M | 0.03% | 00.0% | Unchanged |
| Monashee Investment Management LLC | 20,000 | $1.22M | 0.14% | +20,000 | New |
| Maven Securities LTD | 20,000 | $1.22M | 0.07% | +20,000 | New |
| Ovata Capital Management Ltd | 20,000 | $1.22M | 0.64% | +20,000 | New |
| Manufacturers Life Insurance Company, The | 19,865 | $1.21M | 0.00% | +19,865 | New |
| Bank of America Corp | 19,004 | $1.16M | 0.00% | −259,858−93.2% | Reduced |
| Barclays PLC | 16,445 | $1.00M | 0.00% | +7,200+77.9% | Added |
| Brevan Howard Capital Management LP | 16,180 | $987.3K | 0.09% | +16,180 | New |
| Man Group plc | 15,921 | $971.5K | 0.00% | +2,782+21.2% | Added |
| Citigroup Inc | 15,118 | $922.5K | 0.00% | −8,406−35.7% | Reduced |
| Dimensional Fund Advisors LP | 15,040 | $917.7K | 0.00% | +1,330+9.7% | Added |
| HRT Financial LP | 14,764 | $900.0K | 0.01% | +14,764 | New |
| Group One Trading, L.P. | 13,522 | $825.1K | 0.03% | +13,362+8,351.3% | Added |
| Balyasny Asset Management LLC | 13,311 | $812.2K | 0.00% | +13,311 | New |
| PCG Wealth Advisors, LLC | 12,917 | $788.2K | 0.37% | +12,917 | New |
| J. Goldman & Co LP | 12,336 | $752.7K | 0.03% | −5,664−31.5% | Reduced |
| Renaissance Technologies LLC | 12,104 | $739.0K | 0.00% | −68,700−85.0% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 11,776 | $718.6K | 0.05% | +11,776 | New |
| Marathon Trading Investment Management LLC | 9,000 | $549.2K | 0.22% | +9,000 | New |
| American Century Companies Inc | 7,612 | $464.5K | 0.00% | +7,612 | New |
| BNP Paribas Arbitrage, SA | 6,750 | $411.9K | 0.00% | +6,750 | New |
| Charles Schwab Investment Management Inc | 6,689 | $408.2K | 0.00% | +6,689 | New |
| Squarepoint Ops LLC | 6,406 | $390.9K | 0.00% | +6,406 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 5,627 | $343.4K | 0.00% | −5,904−51.2% | Reduced |
| Windmill Hill Asset Management Ltd | 5,268 | $321.5K | 0.12% | +5,268 | New |
| Norges Bank | 5,000 | $305.1K | 0.00% | +5,000 | New |
| Standard Life Aberdeen plc | 4,999 | $305.0K | 0.00% | +4,999 | New |
| Trexquant Investment LP | 4,343 | $265.0K | 0.01% | +4,343 | New |
| Cerity Partners LLC | 4,261 | $260.0K | 0.00% | +4,261 | New |
| Engineers Gate Manager LP | 4,244 | $259.0K | 0.01% | +4,244 | New |
| Boulder Hill Capital Management LP | 4,200 | $256.3K | 0.11% | +4,200 | New |
| Schonfeld Strategic Advisors LLC | 4,028 | $245.8K | 0.00% | +4,028 | New |
| Coastal Bridge Advisors, LLC | 3,846 | $234.7K | 0.05% | +3,846 | New |
| Chase Investment Counsel Corp | 3,768 | $229.0K | 0.09% | +3,768 | New |
| Polymer Capital Management (HK) LTD | 3,726 | $227.4K | 0.06% | +3,726 | New |