Skip to main content

Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
111
+51 vs. Q4 2023
Shares held
15.9M
+7.90M (+98.6%) vs. Q4 2023
Total value
$971.3M
+$792.7M (+443.9%) vs. Q4 2023
New holders
58
30 more added
Sold out
7
17 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 111 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ1 2024: $971.3M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2023.

Institutions holding PRAX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Macquarie Group Ltd966$590.00%+966New
UBS Group AG8$4880.00%−2,691−99.7%Reduced
FSA Wealth Management LLC21$1.28K0.00%00.0%Unchanged
Quest Partners LLC109$6.65K0.00%+109New
Deutsche Bank AG152$9.28K0.00%00.0%Unchanged
Rhumbline Advisers152$9.28K0.00%00.0%Unchanged
Wells Fargo & Company654$39.9K0.00%+587+876.1%Added
Tower Research Capital LLC (TRC)1,848$112.8K0.00%+1,848New
SG Americas Securities, LLC2,465$150.0K0.00%+2,465New
Simplex Trading, LLC3,355$204.0K0.01%+1,963+141.0%Added
Jump Financial, LLC3,449$210.5K0.01%+3,449New
Polymer Capital Management (HK) LTD3,726$227.4K0.06%+3,726New
Chase Investment Counsel Corp3,768$229.0K0.09%+3,768New
Coastal Bridge Advisors, LLC3,846$234.7K0.05%+3,846New
Schonfeld Strategic Advisors LLC4,028$245.8K0.00%+4,028New
Boulder Hill Capital Management LP4,200$256.3K0.11%+4,200New
Engineers Gate Manager LP4,244$259.0K0.01%+4,244New
Cerity Partners LLC4,261$260.0K0.00%+4,261New
Trexquant Investment LP4,343$265.0K0.01%+4,343New
Standard Life Aberdeen plc4,999$305.0K0.00%+4,999New
Norges Bank5,000$305.1K0.00%+5,000New
Windmill Hill Asset Management Ltd5,268$321.5K0.12%+5,268New
Connor, Clark & Lunn Investment Management Ltd.5,627$343.4K0.00%−5,904−51.2%Reduced
Squarepoint Ops LLC6,406$390.9K0.00%+6,406New
Charles Schwab Investment Management Inc6,689$408.2K0.00%+6,689New
BNP Paribas Arbitrage, SA6,750$411.9K0.00%+6,750New
American Century Companies Inc7,612$464.5K0.00%+7,612New
Marathon Trading Investment Management LLC9,000$549.2K0.22%+9,000New
Y-Intercept (Hong Kong) Ltd11,776$718.6K0.05%+11,776New
Renaissance Technologies LLC12,104$739.0K0.00%−68,700−85.0%Reduced
J. Goldman & Co LP12,336$752.7K0.03%−5,664−31.5%Reduced
PCG Wealth Advisors, LLC12,917$788.2K0.37%+12,917New
Balyasny Asset Management LLC13,311$812.2K0.00%+13,311New
Group One Trading, L.P.13,522$825.1K0.03%+13,362+8,351.3%Added
HRT Financial LP14,764$900.0K0.01%+14,764New
Dimensional Fund Advisors LP15,040$917.7K0.00%+1,330+9.7%Added
Citigroup Inc15,118$922.5K0.00%−8,406−35.7%Reduced
Man Group plc15,921$971.5K0.00%+2,782+21.2%Added
Brevan Howard Capital Management LP16,180$987.3K0.09%+16,180New
Barclays PLC16,445$1.00M0.00%+7,200+77.9%Added
Bank of America Corp19,004$1.16M0.00%−259,858−93.2%Reduced
Manufacturers Life Insurance Company, The19,865$1.21M0.00%+19,865New
Monashee Investment Management LLC20,000$1.22M0.14%+20,000New
Maven Securities LTD20,000$1.22M0.07%+20,000New
Ovata Capital Management Ltd20,000$1.22M0.64%+20,000New
Bridgeway Capital Management, LLC21,152$1.29M0.03%00.0%Unchanged
Two Sigma Investments, LP23,372$1.43M0.00%+13,946+148.0%Added
Alyeska Investment Group, L.P.25,000$1.53M0.01%+25,000New
Citadel Advisors LLC26,008$1.59M0.00%−30,471−54.0%Reduced
StemPoint Capital LP26,893$1.64M0.44%+26,893New
Woodline Partners LP27,263$1.66M0.02%+27,263New
Northern Trust Corp27,279$1.66M0.00%+7,915+40.9%Added
Voloridge Investment Management, LLC27,667$1.69M0.01%+27,667New
UBS Oconnor LLC34,729$2.12M0.06%+12,451+55.9%Added
Atom Investors LP34,867$2.13M0.27%+4,830+16.1%Added
TD Asset Management Inc35,000$2.14M0.00%+35,000New
Soleus Capital Management, L.P.37,268$2.27M0.20%+37,268New
Wellington Management Group LLP39,565$2.41M0.00%+39,565New
Superstring Capital Management LP40,119$2.45M1.62%+40,119New
Boothbay Fund Management, LLC42,803$2.61M0.08%−3,907−8.4%Reduced
State Street Corp44,508$2.72M0.00%+13,800+44.9%Added
Fred Alger Management, LLC47,041$2.87M0.01%+47,041New
Jane Street Group, LLC47,066$2.87M0.00%+36,490+345.0%Added
Farallon Capital Management, L.L.C.50,000$3.05M0.02%+50,000New
JPMorgan Chase & Co51,372$3.13M0.00%+51,355+302,088.2%Added
Jacobs Levy Equity Management, Inc51,548$3.15M0.01%−14,940−22.5%Reduced
72 Investment Holdings, LLC65,933$4.02M6.00%00.0%Unchanged
Assenagon Asset Management S.A.71,253$4.35M0.01%+71,253New
Altium Capital Management LP78,100$4.77M2.13%+78,100New
Acadian Asset Management LLC82,254$5.02M0.02%−15,795−16.1%Reduced
Hudson Bay Capital Management LP93,000$5.67M0.05%+93,000New
LMR Partners LLP94,332$5.76M0.15%+94,332New
Invesco Ltd.95,181$5.81M0.00%+95,181New
Goldman Sachs Group Inc98,635$6.02M0.00%+98,635New
Morgan Stanley100,136$6.11M0.00%+83,203+491.4%Added
Susquehanna International Group, LLP106,159$6.48M0.01%+57,875+119.9%Added
Tri Locum Partners LP106,494$6.50M2.25%−142,267−57.2%Reduced
Marshall Wace, LLP121,024$7.38M0.01%+72,182+147.8%Added
Baker Bros. Advisors LP131,533$8.03M0.10%00.0%Unchanged
Qube Research & Technologies Ltd132,942$8.11M0.01%+107,838+429.6%Added
Geode Capital Management, LLC134,717$8.22M0.00%+41,759+44.9%Added
Franklin Resources Inc145,295$8.87M0.00%+145,295New
Logos Global Management LP150,000$9.15M0.96%+150,000New
Ally Bridge Group (NY) LLC159,486$9.73M5.41%+89,062+126.5%Added
Acuta Capital Partners, LLC162,302$9.90M6.43%−137,334−45.8%Reduced
Ikarian Capital, LLC168,388$10.3M2.79%−31,612−15.8%Reduced
Millennium Management LLC176,952$10.8M0.01%+154,606+691.9%Added
Sphera Funds Management Ltd.177,139$10.8M1.75%−151,847−46.2%Reduced
Silverarc Capital Management, LLC190,556$11.6M3.26%−93,285−32.9%Reduced
CIBC Asset Management Inc192,304$11.7M0.04%+18,436+10.6%Added
Vestal Point Capital, LP210,000$12.8M1.06%+210,000New
BlackRock Inc.221,745$13.5M0.00%+95,209+75.2%Added
Laurion Capital Management LP225,000$13.7M0.38%+225,000New
Octagon Capital Advisors LP260,000$15.9M1.93%+260,000New
Driehaus Capital Management LLC266,496$16.3M0.16%+266,496New
Janus Henderson Group PLC310,059$18.9M0.01%+310,059New
5AM Venture Management, LLC340,000$20.7M4.65%+340,000New
Kingdon Capital Management, L.L.C.350,000$21.4M2.83%+3,335+1.0%Added
Velan Capital Investment Management LP350,666$21.4M11.57%+5,000+1.4%Added
FMR LLC442,621$27.0M0.00%+442,506+384,787.8%Added