Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 144
- −6 vs. Q1 2025
- Shares held
- 24.2M
- +699.7K (+3.0%) vs. Q1 2025
- Total value
- $1.02B
- +$126.3M (+14.2%) vs. Q1 2025
- New holders
- 25
- 65 more added
- Sold out
- 31
- 36 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Janus Henderson Group PLC | 2,533,405 | $106.5M | 0.05% | +1,026,969+68.2% | Added |
| Adage Capital Partners GP, L.L.C. | 1,974,585 | $83.0M | 0.14% | +231,827+13.3% | Added |
| Cormorant Asset Management, LP | 1,625,000 | $68.3M | 5.09% | −120,000−6.9% | Reduced |
| BlackRock, Inc. | 1,590,128 | $66.9M | 0.00% | +173,193+12.2% | Added |
| Price T Rowe Associates Inc | 1,473,075 | $61.9M | 0.01% | +377,350+34.4% | Added |
| Morgan Stanley | 1,226,339 | $51.6M | 0.00% | +12,670+1.0% | Added |
| Vanguard Group Inc | 1,215,644 | $51.1M | 0.00% | +128,624+11.8% | Added |
| Soleus Capital Management, L.P. | 966,740 | $40.7M | 2.81% | −173,000−15.2% | Reduced |
| Point72 Asset Management, L.P. | 954,075 | $40.1M | 0.09% | +620,541+186.1% | Added |
| Perceptive Advisors LLC | 752,921 | $31.7M | 1.19% | −227,973−23.2% | Reduced |
| State Street Corp | 698,093 | $29.4M | 0.00% | −38,946−5.3% | Reduced |
| Baker Bros. Advisors LP | 689,488 | $29.0M | 0.28% | +357,955+108.0% | Added |
| Deerfield Management Company, L.P. (Series C) | 686,931 | $28.9M | 0.52% | +67,000+10.8% | Added |
| Assenagon Asset Management S.A. | 604,298 | $25.4M | 0.04% | +96,898+19.1% | Added |
| Driehaus Capital Management LLC | 530,988 | $22.3M | 0.18% | +49,390+10.3% | Added |
| Bank of America Corp | 453,403 | $19.1M | 0.00% | −7,304−1.6% | Reduced |
| Geode Capital Management, LLC | 451,731 | $19.0M | 0.00% | +33,715+8.1% | Added |
| CIBC Asset Management Inc | 388,759 | $16.3M | 0.05% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 369,254 | $15.5M | 0.04% | −33,749−8.4% | Reduced |
| Franklin Resources Inc | 314,150 | $13.2M | 0.00% | +230.0% | Added |
| Ikarian Capital, LLC | 276,950 | $11.6M | 3.85% | +131,448+90.3% | Added |
| Goldman Sachs Group Inc | 225,992 | $9.50M | 0.00% | +48,728+27.5% | Added |
| Logos Global Management LP | 225,000 | $9.46M | 1.26% | +225,000 | New |
| Standard Life Aberdeen plc | 214,056 | $9.00M | 0.02% | +126,153+143.5% | Added |
| Northern Trust Corp | 213,712 | $8.99M | 0.00% | +48,529+29.4% | Added |
| Tri Locum Partners LP | 195,432 | $8.22M | 2.49% | +111,773+133.6% | Added |
| 5AM Venture Management, LLC | 170,000 | $7.15M | 2.75% | 00.0% | Unchanged |
| Vivo Capital, LLC | 167,600 | $7.05M | 0.72% | +167,600 | New |
| Charles Schwab Investment Management Inc | 152,444 | $6.41M | 0.00% | +11,364+8.1% | Added |
| Velan Capital Investment Management LP | 149,334 | $6.28M | 6.28% | −35,666−19.3% | Reduced |
| Alyeska Investment Group, L.P. | 125,000 | $5.26M | 0.02% | −25,000−16.7% | Reduced |
| Verition Fund Management LLC | 118,482 | $4.98M | 0.03% | −81,175−40.7% | Reduced |
| Boothbay Fund Management, LLC | 118,121 | $4.97M | 0.16% | +71,495+153.3% | Added |
| Sphera Funds Management Ltd. | 109,757 | $4.62M | 1.21% | −30,903−22.0% | Reduced |
| Schonfeld Strategic Advisors LLC | 100,702 | $4.23M | 0.03% | +94,628+1,557.9% | Added |
| UBS Asset Management Americas Inc | 96,945 | $4.08M | 0.00% | +9,864+11.3% | Added |
| Barclays PLC | 88,724 | $3.73M | 0.00% | +56,956+179.3% | Added |
| UBS Group AG | 86,534 | $3.64M | 0.00% | −106,375−55.1% | Reduced |
| PFM Health Sciences, LP | 84,713 | $3.56M | 0.31% | −76,153−47.3% | Reduced |
| Ally Bridge Group (NY) LLC | 80,880 | $3.40M | 2.83% | −14,702−15.4% | Reduced |
| Pictet Asset Management Holding SA | 79,143 | $3.33M | 0.00% | +555+0.7% | Added |
| Acuta Capital Partners, LLC | 74,087 | $3.12M | 4.35% | −13,054−15.0% | Reduced |
| Kennedy Capital Management, Inc. | 70,445 | $2.96M | 0.07% | +5,180+7.9% | Added |
| HighVista Strategies LLC | 67,288 | $2.83M | 1.04% | +28,002+71.3% | Added |
| 72 Investment Holdings, LLC | 65,933 | $2.77M | 7.23% | 00.0% | Unchanged |
| TD Asset Management Inc | 63,938 | $2.69M | 0.00% | +26,800+72.2% | Added |
| Candriam Luxembourg S.C.A. | 63,671 | $2.68M | 0.02% | 00.0% | Unchanged |
| Exome Asset Management LLC | 59,002 | $2.48M | 2.05% | +59,002 | New |
| Manufacturers Life Insurance Company, The | 56,131 | $2.36M | 0.00% | +23,639+72.8% | Added |
| Wellington Management Group LLP | 55,881 | $2.35M | 0.00% | +5,105+10.1% | Added |
| Bank of New York Mellon Corp | 52,553 | $2.21M | 0.00% | +6,246+13.5% | Added |
| Susquehanna International Group, LLP | 46,927 | $1.97M | 0.00% | +12,179+35.0% | Added |
| Woodline Partners LP | 45,952 | $1.93M | 0.01% | −129,775−73.9% | Reduced |
| Jacobs Levy Equity Management, Inc | 45,082 | $1.90M | 0.01% | +5,083+12.7% | Added |
| Caption Management, LLC | 39,036 | $1.64M | 0.15% | +20,756+113.5% | Added |
| Nuveen, LLC | 38,549 | $1.62M | 0.00% | +23,787+161.1% | Added |
| FMR LLC | 38,100 | $1.60M | 0.00% | +2,381+6.7% | Added |
| B Group, Inc. | 35,000 | $1.47M | 1.27% | +16,000+84.2% | Added |
| StemPoint Capital LP | 32,255 | $1.36M | 0.44% | +32,255 | New |
| Swiss National Bank | 30,800 | $1.30M | 0.00% | +3,700+13.7% | Added |
| Algert Global LLC | 27,570 | $1.16M | 0.02% | +6,080+28.3% | Added |
| Rhumbline Advisers | 27,341 | $1.15M | 0.00% | +3,047+12.5% | Added |
| Simplex Trading, LLC | 25,328 | $1.06M | 0.03% | +22,030+668.0% | Added |
| Rafferty Asset Management, LLC | 24,805 | $1.04M | 0.00% | −4,440−15.2% | Reduced |
| Capital Fund Management S.A. | 24,292 | $1.02M | 0.01% | +24,292 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 23,873 | $1.01M | 0.00% | +12,165+103.9% | Added |
| Royal Bank of Canada | 22,593 | $950.0K | 0.00% | +22,485+20,819.4% | Added |
| UBS Oconnor LLC | 21,892 | $920.6K | 0.03% | −4,901−18.3% | Reduced |
| Prelude Capital Management, LLC | 19,900 | $836.8K | 0.08% | +19,900 | New |
| D. E. Shaw & Co., Inc. | 19,056 | $801.3K | 0.00% | +6,848+56.1% | Added |
| Alliancebernstein L.P. | 18,040 | $758.6K | 0.00% | −33,076−64.7% | Reduced |
| Legal & General Group Plc | 16,670 | $701.0K | 0.00% | +2,261+15.7% | Added |
| California State Teachers Retirement System | 16,346 | $687.3K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 15,939 | $670.2K | 0.00% | +4,261+36.5% | Added |
| Sofinnova Investments, Inc. | 15,717 | $660.9K | 0.04% | −141,923−90.0% | Reduced |
| State of Wisconsin Investment Board | 14,759 | $620.6K | 0.00% | +148+1.0% | Added |
| AQR Capital Management LLC | 14,580 | $613.1K | 0.00% | +14,580 | New |
| JPMorgan Chase & Co | 13,938 | $586.1K | 0.00% | +2,459+21.4% | Added |
| Jane Street Group, LLC | 13,003 | $546.8K | 0.00% | +3,514+37.0% | Added |
| Deutsche Bank AG | 12,124 | $509.8K | 0.00% | −1,737−12.5% | Reduced |
| Gsa Capital Partners LLP | 12,008 | $505.0K | 0.04% | −969−7.5% | Reduced |
| Citigroup Inc | 11,866 | $499.0K | 0.00% | −33,766−74.0% | Reduced |
| Wells Fargo & Company | 11,252 | $473.1K | 0.00% | +2,735+32.1% | Added |
| Alps Advisors Inc | 10,994 | $462.3K | 0.00% | −3,944−26.4% | Reduced |
| MetLife Investment Management | 10,520 | $442.4K | 0.00% | −77−0.7% | Reduced |
| Hussman Strategic Advisors, Inc. | 10,500 | $441.5K | 0.10% | 00.0% | Unchanged |
| Citadel Advisors LLC | 10,366 | $435.9K | 0.00% | −51,844−83.3% | Reduced |
| Silverarc Capital Management, LLC | 10,000 | $420.5K | 0.09% | −156,074−94.0% | Reduced |
| Intech Investment Management LLC | 8,719 | $366.6K | 0.00% | −79−0.9% | Reduced |
| Brevan Howard Capital Management LP | 8,503 | $357.6K | 0.00% | +8,503 | New |
| New York State Common Retirement Fund | 6,600 | $277.5K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 6,509 | $273.7K | 0.00% | −12,299−65.4% | Reduced |
| Creative Planning | 6,495 | $273.1K | 0.00% | +6,495 | New |
| State Board of Administration of Florida Retirement System | 6,425 | $270.2K | 0.00% | +385+6.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 5,750 | $241.8K | 0.01% | +5,750 | New |
| Cerity Partners LLC | 5,611 | $235.9K | 0.00% | +5,611 | New |
| Profund Advisors LLC | 5,261 | $221.2K | 0.01% | −847−13.9% | Reduced |
| Virtu Financial LLC | 5,058 | $213.0K | 0.01% | +5,058 | New |
| Norges Bank | 5,000 | $210.3K | 0.00% | −79,200−94.1% | Reduced |
| Jefferies Financial Group Inc. | 5,000 | $210.3K | 0.00% | +5,000 | New |