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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
144
−6 vs. Q1 2025
Shares held
24.2M
+699.7K (+3.0%) vs. Q1 2025
Total value
$1.02B
+$126.3M (+14.2%) vs. Q1 2025
New holders
25
65 more added
Sold out
31
36 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 144 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2025: $1.02B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2025.

Institutions holding PRAX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd2$00.00%+1+100.0%Added
National Bank of Canada1$420.00%+1New
Essential Partners LLC1$420.00%+1New
Twin Peaks Wealth Advisors, LLC1$480.00%+1New
Parkside Financial Bank & Trust10$4210.00%00.0%Unchanged
EverSource Wealth Advisors, LLC18$7570.00%+7+63.6%Added
FSA Wealth Management LLC21$8830.00%00.0%Unchanged
SRS Capital Advisors, Inc.23$9680.00%+23New
Hemington Wealth Management30$1.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.24$1.01K0.00%+19+380.0%Added
Larson Financial Group LLC38$1.60K0.00%+38New
IFP Advisors, Inc0$1.89K0.00%−1−100.0%Reduced
Rothschild Investment LLC50$2.10K0.00%+45+900.0%Added
Advisor Group Holdings, Inc.54$2.27K0.00%−12−18.2%Reduced
Allworth Financial LP69$2.90K0.00%+63+1,050.0%Added
Daiwa Securities Group Inc.62$3.00K0.00%00.0%Unchanged
SBI Securities Co., Ltd.75$3.15K0.00%+10+15.4%Added
Quest Partners LLC116$4.88K0.00%−32−21.6%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.133$6.00K0.00%+133New
GAMMA Investing LLC155$6.52K0.00%+49+46.2%Added
US Bancorp166$6.98K0.00%−700−80.8%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)167$7.02K0.00%00.0%Unchanged
Public Employees Retirement Association of Colorado217$9.00K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd219$9.21K0.01%+219New
Farther Finance Advisors, LLC230$9.67K0.00%+30+15.0%Added
Russell Investments Group, Ltd.249$10.5K0.00%+249New
Skopos Labs, Inc.298$12.5K0.00%+298New
Sterling Capital Management LLC445$18.7K0.00%+427+2,372.2%Added
GF Fund Management Co. Ltd.477$20.1K0.00%00.0%Unchanged
Amalgamated Bank599$25.0K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC629$26.4K0.00%+295+88.3%Added
CWM, LLC753$32.0K0.00%+676+877.9%Added
Mirae Asset Global Investments Co., Ltd.787$33.1K0.00%+112+16.6%Added
Ameritas Investment Partners, Inc.1,689$71.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,837$77.2K0.00%+359+24.3%Added
BNP Paribas Arbitrage, SA2,047$86.1K0.00%−5,404−72.5%Reduced
Virtus Investment Advisers, Inc.2,088$87.8K0.03%−228−9.8%Reduced
KLP Kapitalforvaltning AS2,800$117.7K0.00%00.0%Unchanged
Toronto Dominion Bank3,100$130.4K0.00%+3,100New
Police & Firemen's Retirement System of New Jersey3,789$159.3K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.4,091$172.0K0.02%+47+1.2%Added
Quarry LP4,800$201.8K0.05%+900+23.1%Added
Voya Investment Management LLC4,919$206.8K0.00%+4,919New
Norges Bank5,000$210.3K0.00%−79,200−94.1%Reduced
Jefferies Financial Group Inc.5,000$210.3K0.00%+5,000New
Maven Securities LTD5,000$210.3K0.05%+5,000New
Virtu Financial LLC5,058$213.0K0.01%+5,058New
Profund Advisors LLC5,261$221.2K0.01%−847−13.9%Reduced
Cerity Partners LLC5,611$235.9K0.00%+5,611New
Susquehanna Portfolio Strategies, LLC5,750$241.8K0.01%+5,750New
State Board of Administration of Florida Retirement System6,425$270.2K0.00%+385+6.4%Added
Creative Planning6,495$273.1K0.00%+6,495New
Two Sigma Investments, LP6,509$273.7K0.00%−12,299−65.4%Reduced
New York State Common Retirement Fund6,600$277.5K0.00%00.0%Unchanged
Brevan Howard Capital Management LP8,503$357.6K0.00%+8,503New
Intech Investment Management LLC8,719$366.6K0.00%−79−0.9%Reduced
Silverarc Capital Management, LLC10,000$420.5K0.09%−156,074−94.0%Reduced
Citadel Advisors LLC10,366$435.9K0.00%−51,844−83.3%Reduced
Hussman Strategic Advisors, Inc.10,500$441.5K0.10%00.0%Unchanged
MetLife Investment Management10,520$442.4K0.00%−77−0.7%Reduced
Alps Advisors Inc10,994$462.3K0.00%−3,944−26.4%Reduced
Wells Fargo & Company11,252$473.1K0.00%+2,735+32.1%Added
Citigroup Inc11,866$499.0K0.00%−33,766−74.0%Reduced
Gsa Capital Partners LLP12,008$505.0K0.04%−969−7.5%Reduced
Deutsche Bank AG12,124$509.8K0.00%−1,737−12.5%Reduced
Jane Street Group, LLC13,003$546.8K0.00%+3,514+37.0%Added
JPMorgan Chase & Co13,938$586.1K0.00%+2,459+21.4%Added
AQR Capital Management LLC14,580$613.1K0.00%+14,580New
State of Wisconsin Investment Board14,759$620.6K0.00%+148+1.0%Added
Sofinnova Investments, Inc.15,717$660.9K0.04%−141,923−90.0%Reduced
Invesco Ltd.15,939$670.2K0.00%+4,261+36.5%Added
California State Teachers Retirement System16,346$687.3K0.00%00.0%Unchanged
Legal & General Group Plc16,670$701.0K0.00%+2,261+15.7%Added
Alliancebernstein L.P.18,040$758.6K0.00%−33,076−64.7%Reduced
D. E. Shaw & Co., Inc.19,056$801.3K0.00%+6,848+56.1%Added
Prelude Capital Management, LLC19,900$836.8K0.08%+19,900New
UBS Oconnor LLC21,892$920.6K0.03%−4,901−18.3%Reduced
Royal Bank of Canada22,593$950.0K0.00%+22,485+20,819.4%Added
Mirae Asset Global ETFs Holdings Ltd.23,873$1.01M0.00%+12,165+103.9%Added
Capital Fund Management S.A.24,292$1.02M0.01%+24,292New
Rafferty Asset Management, LLC24,805$1.04M0.00%−4,440−15.2%Reduced
Simplex Trading, LLC25,328$1.06M0.03%+22,030+668.0%Added
Rhumbline Advisers27,341$1.15M0.00%+3,047+12.5%Added
Algert Global LLC27,570$1.16M0.02%+6,080+28.3%Added
Swiss National Bank30,800$1.30M0.00%+3,700+13.7%Added
StemPoint Capital LP32,255$1.36M0.44%+32,255New
B Group, Inc.35,000$1.47M1.27%+16,000+84.2%Added
FMR LLC38,100$1.60M0.00%+2,381+6.7%Added
Nuveen, LLC38,549$1.62M0.00%+23,787+161.1%Added
Caption Management, LLC39,036$1.64M0.15%+20,756+113.5%Added
Jacobs Levy Equity Management, Inc45,082$1.90M0.01%+5,083+12.7%Added
Woodline Partners LP45,952$1.93M0.01%−129,775−73.9%Reduced
Susquehanna International Group, LLP46,927$1.97M0.00%+12,179+35.0%Added
Bank of New York Mellon Corp52,553$2.21M0.00%+6,246+13.5%Added
Wellington Management Group LLP55,881$2.35M0.00%+5,105+10.1%Added
Manufacturers Life Insurance Company, The56,131$2.36M0.00%+23,639+72.8%Added
Exome Asset Management LLC59,002$2.48M2.05%+59,002New
Candriam Luxembourg S.C.A.63,671$2.68M0.02%00.0%Unchanged
TD Asset Management Inc63,938$2.69M0.00%+26,800+72.2%Added
72 Investment Holdings, LLC65,933$2.77M7.23%00.0%Unchanged