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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
134
+22 vs. Q2 2024
Shares held
18.9M
+1.74M (+10.1%) vs. Q2 2024
Total value
$1.09B
+$382.6M (+54.0%) vs. Q2 2024
New holders
35
43 more added
Sold out
13
45 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 134 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ3 2024: $1.09B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2024.

Institutions holding PRAX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.1,302,435$74.9M0.00%+1,302,435New
Perceptive Advisors LLC1,164,035$67.0M1.44%+413,805+55.2%Added
Price T Rowe Associates Inc1,120,080$64.5M0.01%+181,501+19.3%Added
Vanguard Group Inc1,038,994$59.8M0.00%+61,849+6.3%Added
Point72 Asset Management, L.P.1,033,244$59.5M0.21%−18,457−1.8%Reduced
Capital Research Global Investors997,094$57.4M0.01%+997,094New
Cormorant Asset Management, LP870,000$50.1M2.65%+185,000+27.0%Added
Adage Capital Partners GP, L.L.C.854,083$49.1M0.09%−280,000−24.7%Reduced
State Street Corp789,624$45.4M0.00%−29,518−3.6%Reduced
Ra Capital Management, L.P.761,955$43.8M0.51%−473,644−38.3%Reduced
VR Adviser, LLC706,131$40.6M2.13%00.0%Unchanged
Verition Fund Management LLC559,151$32.2M0.22%−189,169−25.3%Reduced
Franklin Resources Inc445,233$31.2M0.01%+205,335+85.6%Added
Janus Henderson Group PLC523,566$30.1M0.02%+141,881+37.2%Added
Geode Capital Management, LLC398,838$23.0M0.00%+3,779+1.0%Added
Kingdon Capital Management, L.L.C.368,000$21.2M3.11%−47,000−11.3%Reduced
Velan Capital Investment Management LP350,666$20.2M21.90%00.0%Unchanged
5AM Venture Management, LLC340,000$19.6M4.04%00.0%Unchanged
Baker Bros. Advisors LP323,105$18.6M0.19%+191,572+145.6%Added
Nuveen Asset Management, LLC304,827$17.5M0.00%+130,160+74.5%Added
Goldman Sachs Group Inc279,620$16.1M0.00%+148,623+113.5%Added
FMR LLC273,895$15.8M0.00%−17,084−5.9%Reduced
Soleus Capital Management, L.P.259,398$14.9M1.24%−273,617−51.3%Reduced
CIBC Asset Management Inc248,939$14.3M0.05%+56,272+29.2%Added
Wellington Management Group LLP219,907$12.7M0.00%+168,394+326.9%Added
PFM Health Sciences, LP183,092$10.5M0.60%−270,054−59.6%Reduced
StemPoint Capital LP174,034$10.0M3.00%+144,775+494.8%Added
Marshall Wace, LLP170,095$9.79M0.01%−78,286−31.5%Reduced
Driehaus Capital Management LLC166,056$9.55M0.08%−98,632−37.3%Reduced
Candriam Luxembourg S.C.A.162,031$9.32M0.05%+162,031New
Sphera Funds Management Ltd.152,307$8.76M1.43%−131,117−46.3%Reduced
Northern Trust Corp152,267$8.76M0.00%+104,198+216.8%Added
Charles Schwab Investment Management Inc137,052$7.89M0.00%+89,578+188.7%Added
Octagon Capital Advisors LP130,000$7.48M1.20%−130,000−50.0%Reduced
Invesco Ltd.107,713$6.20M0.00%+98,901+1,122.3%Added
Citigroup Inc83,350$4.80M0.00%+75,739+995.1%Added
Morgan Stanley80,500$4.63M0.00%−103,819−56.3%Reduced
Voloridge Investment Management, LLC75,187$4.33M0.02%+39,964+113.5%Added
Ally Bridge Group (NY) LLC73,185$4.21M2.25%−80,194−52.3%Reduced
Pale Fire Capital SE67,284$3.87M0.61%+67,284New
Silverarc Capital Management, LLC67,045$3.86M0.87%−251−0.4%Reduced
72 Investment Holdings, LLC65,933$3.79M8.16%00.0%Unchanged
Group One Trading, L.P.60,818$3.50M0.14%+60,818New
Acuta Capital Partners, LLC57,500$3.31M2.68%−106,931−65.0%Reduced
Walleye Capital LLC55,613$3.20M0.03%+55,613New
Bank of America Corp49,849$2.87M0.00%+11,295+29.3%Added
Bank of New York Mellon Corp48,207$2.77M0.00%−1,303−2.6%Reduced
Citadel Advisors LLC48,034$2.76M0.00%+25,388+112.1%Added
D. E. Shaw & Co., Inc.46,364$2.67M0.00%+25,287+120.0%Added
Qube Research & Technologies Ltd44,703$2.57M0.00%−45,990−50.7%Reduced
TD Asset Management Inc43,898$2.54M0.00%−7,414−14.4%Reduced
Jacobs Levy Equity Management, Inc39,999$2.30M0.01%−23,362−36.9%Reduced
Jane Street Group, LLC38,545$2.22M0.00%+6,452+20.1%Added
UBS Oconnor LLC38,490$2.21M0.05%+2,761+7.7%Added
Barclays PLC37,130$2.14M0.00%+20,759+126.8%Added
Rafferty Asset Management, LLC35,359$2.03M0.01%−5,999−14.5%Reduced
Manufacturers Life Insurance Company, The35,139$2.02M0.00%−169−0.5%Reduced
Moody Aldrich Partners LLC31,605$1.82M0.33%+7,224+29.6%Added
UBS Group AG29,550$1.70M0.00%+2,773+10.4%Added
Susquehanna International Group, LLP28,994$1.67M0.00%+28,994New
Schonfeld Strategic Advisors LLC28,451$1.64M0.01%+28,451New
AQR Capital Management LLC25,268$1.45M0.00%+25,268New
Swiss National Bank25,100$1.44M0.00%−6,900−21.6%Reduced
Rhumbline Advisers23,116$1.33M0.00%+924+4.2%Added
Two Sigma Investments, LP22,766$1.31M0.00%−1,200−5.0%Reduced
Hussman Strategic Advisors, Inc.21,000$1.21M0.30%00.0%Unchanged
Alliancebernstein L.P.18,040$1.04M0.00%00.0%Unchanged
PCG Wealth Advisors, LLC17,359$998.8K0.39%−82−0.5%Reduced
UBS Asset Management Americas Inc15,868$913.0K0.00%−6,014−27.5%Reduced
Trexquant Investment LP15,432$888.0K0.01%−7,375−32.3%Reduced
Squarepoint Ops LLC14,658$843.4K0.00%+1,310+9.8%Added
Legal & General Group Plc13,829$795.7K0.00%−212−1.5%Reduced
Alps Advisors Inc13,429$772.7K0.01%+87+0.7%Added
State of Wisconsin Investment Board12,648$727.8K0.00%+698+5.8%Added
California State Teachers Retirement System12,451$716.4K0.00%−3,494−21.9%Reduced
Simplex Trading, LLC12,418$714.0K0.02%+10,857+695.5%Added
HighVista Strategies LLC10,951$630.1K0.22%+10,951New
Mirae Asset Global ETFs Holdings Ltd.10,877$626.3K0.00%+9,320+598.6%Added
Fred Alger Management, LLC10,423$599.7K0.00%+7,828+301.7%Added
Deutsche Bank AG10,315$593.5K0.00%+2,406+30.4%Added
American Century Companies Inc10,313$593.4K0.00%+10,313New
MetLife Investment Management10,131$582.9K0.00%+5,708+129.1%Added
Assenagon Asset Management S.A.10,096$580.9K0.00%−9,665−48.9%Reduced
Ovata Capital Management Ltd9,777$562.6K0.24%−30,223−75.6%Reduced
BNP Paribas Arbitrage, SA9,525$548.1K0.00%+7,496+369.4%Added
Corebridge Financial, Inc.9,220$530.5K0.00%−57−0.6%Reduced
Caption Management, LLC9,204$529.6K0.06%+9,204New
JPMorgan Chase & Co7,814$449.6K0.00%+448+6.1%Added
Profund Advisors LLC7,047$405.5K0.02%−639−8.3%Reduced
New York State Common Retirement Fund7,000$402.8K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System6,270$360.8K0.00%00.0%Unchanged
Wells Fargo & Company5,866$337.5K0.00%−211−3.5%Reduced
Voya Investment Management LLC5,669$326.2K0.00%−155−2.7%Reduced
SG Americas Securities, LLC5,158$297.0K0.00%+5,158New
Dimensional Fund Advisors LP5,089$292.8K0.00%−1,799−26.1%Reduced
Norges Bank5,000$287.7K0.00%−27,005−84.4%Reduced
Standard Life Aberdeen plc4,999$287.6K0.00%00.0%Unchanged
SEI Investments Co4,889$281.3K0.00%+4,889New
Engineers Gate Manager LP4,737$272.6K0.01%−7,922−62.6%Reduced
Cerity Partners LLC4,388$252.5K0.00%+4,388New