Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 87
- −17 vs. Q4 2022
- Shares held
- 53.2M
- +7.81M (+17.2%) vs. Q4 2022
- Total value
- $43.1M
- −$65.0M (−60.1%) vs. Q4 2022
- New holders
- 12
- 39 more added
- Sold out
- 29
- 19 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Velan Capital Investment Management LP | 5,185,000 | $4.19M | 3.72% | +5,185,000 | New |
| Kingdon Capital Management, L.L.C. | 4,700,000 | $3.80M | 0.89% | +1,844,011+64.6% | Added |
| Avidity Partners Management LP | 4,281,700 | $3.46M | 0.11% | +4,281,700 | New |
| Bank of America Corp | 4,025,769 | $3.26M | 0.00% | +2,510,848+165.7% | Added |
| Verition Fund Management LLC | 2,962,335 | $2.40M | 0.04% | +1,291,964+77.3% | Added |
| BlackRock Inc. | 2,888,281 | $2.34M | 0.00% | −83,481−2.8% | Reduced |
| Tri Locum Partners LP | 2,488,354 | $2.01M | 0.61% | +2,464,207+10,205.0% | Added |
| PFM Health Sciences, LP | 2,176,594 | $1.76M | 0.08% | −600,873−21.6% | Reduced |
| Vanguard Group Inc | 2,139,901 | $1.73M | 0.00% | +353,605+19.8% | Added |
| Great Point Partners LLC | 2,032,550 | $1.64M | 0.32% | +2,032,550 | New |
| Adage Capital Partners GP, L.L.C. | 1,922,262 | $1.56M | 0.00% | −333,779−14.8% | Reduced |
| Baker Bros. Advisors LP | 1,879,915 | $1.52M | 0.01% | +49,600+2.7% | Added |
| Vida Ventures Advisors, LLC | 1,469,665 | $1.19M | 1.63% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 1,396,407 | $1.13M | 0.00% | +42,877+3.2% | Added |
| CIBC Asset Management Inc | 1,284,471 | $1.04M | 0.00% | +904,834+238.3% | Added |
| Blackstone Group Inc. | 1,054,109 | $853.8K | 0.00% | −3,840,000−78.5% | Reduced |
| 72 Investment Holdings, LLC | 988,995 | $800.1K | 0.38% | 00.0% | Unchanged |
| State Street Corp | 968,570 | $783.6K | 0.00% | +82,777+9.3% | Added |
| Geode Capital Management, LLC | 835,576 | $676.0K | 0.00% | +141,994+20.5% | Added |
| Morgan Stanley | 828,534 | $670.3K | 0.00% | +646,477+355.1% | Added |
| Harvard Management Co Inc | 778,517 | $629.8K | 0.07% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 760,686 | $615.4K | 0.00% | +41,234+5.7% | Added |
| Citadel Advisors LLC | 623,787 | $504.6K | 0.00% | −131,543−17.4% | Reduced |
| Schonfeld Strategic Advisors LLC | 531,634 | $430.1K | 0.00% | +463,734+683.0% | Added |
| UBS Oconnor LLC | 507,258 | $410.4K | 0.01% | +507,258 | New |
| Northern Trust Corp | 406,203 | $328.6K | 0.00% | +54,332+15.4% | Added |
| Federated Hermes, Inc. | 387,767 | $313.7K | 0.00% | +19,337+5.2% | Added |
| Renaissance Technologies LLC | 380,000 | $307.0K | 0.00% | +16,000+4.4% | Added |
| Marshall Wace, LLP | 283,695 | $229.8K | 0.00% | +283,695 | New |
| Los Angeles Capital Management LLC | 263,873 | $213.5K | 0.00% | +131,548+99.4% | Added |
| Dimensional Fund Advisors LP | 247,654 | $200.4K | 0.00% | +130,362+111.1% | Added |
| Millennium Management LLC | 175,837 | $142.0K | 0.00% | +8,770+5.2% | Added |
| Two Sigma Advisers, LP | 171,900 | $139.1K | 0.00% | −275,800−61.6% | Reduced |
| Bridgeway Capital Management, LLC | 155,800 | $126.0K | 0.00% | +42,200+37.1% | Added |
| Nuveen Asset Management, LLC | 153,308 | $124.0K | 0.00% | −38,253−20.0% | Reduced |
| J. Goldman & Co LP | 135,000 | $109.2K | 0.01% | +135,000 | New |
| Charles Schwab Investment Management Inc | 129,296 | $104.6K | 0.00% | +18,933+17.2% | Added |
| Bank of New York Mellon Corp | 126,960 | $102.7K | 0.00% | +8,170+6.9% | Added |
| Raymond James & Associates | 115,540 | $93.5K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 104,320 | $84.4K | 0.00% | +84,115+416.3% | Added |
| PEAK6 Investments LLC | 89,468 | $72.4K | 0.00% | +89,468 | New |
| Alliancebernstein L.P. | 80,700 | $65.3K | 0.00% | 00.0% | Unchanged |
| Tekla Capital Management LLC | 75,000 | $60.7K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 74,594 | $60.3K | 0.00% | −85,935−53.5% | Reduced |
| Cornercap Investment Counsel Inc | 73,127 | $59.2K | 0.01% | +152+0.2% | Added |
| Boothbay Fund Management, LLC | 71,243 | $57.6K | 0.00% | +45,683+178.7% | Added |
| Rhumbline Advisers | 63,363 | $51.0K | 0.00% | +7,913+14.3% | Added |
| Susquehanna Fundamental Investments, LLC | 62,252 | $50.4K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 52,800 | $42.7K | 0.00% | −225,972−81.1% | Reduced |
| Point72 Asset Management, L.P. | 50,000 | $40.5K | 0.00% | −50,000−50.0% | Reduced |
| Squarepoint Ops LLC | 46,537 | $37.6K | 0.00% | +20,919+81.7% | Added |
| Occudo Quantitative Strategies LP | 41,263 | $33.4K | 0.00% | −2,447−5.6% | Reduced |
| Price T Rowe Associates Inc | 40,383 | $33.0K | 0.00% | −7,550−15.8% | Reduced |
| JPMorgan Chase & Co | 38,001 | $31.0K | 0.00% | +15,121+66.1% | Added |
| Group One Trading, L.P. | 37,690 | $30.5K | 0.00% | +37,690 | New |
| Alta Wealth Advisors LLC | 31,028 | $25.1K | 0.02% | 00.0% | Unchanged |
| Algert Global LLC | 28,280 | $22.9K | 0.00% | +1,450+5.4% | Added |
| Deutsche Bank AG | 26,273 | $21.3K | 0.00% | +12,309+88.1% | Added |
| Man Group plc | – | $20.3K | 0.00% | – | – |
| Barclays PLC | 24,167 | $19.6K | 0.00% | +13,628+129.3% | Added |
| American International Group, Inc. | 23,019 | $18.6K | 0.00% | +4,488+24.2% | Added |
| State Board of Administration of Florida Retirement System | 20,871 | $16.9K | 0.00% | 00.0% | Unchanged |
| Panagora Asset Management Inc | 20,550 | $16.6K | 0.00% | +1,696+9.0% | Added |
| UBS Group AG | 19,745 | $16.0K | 0.00% | +9,490+92.5% | Added |
| Voya Investment Management LLC | 19,216 | $15.5K | 0.00% | +1,147+6.3% | Added |
| Principal Financial Group Inc | 19,071 | $15.4K | 0.00% | +271+1.4% | Added |
| California State Teachers Retirement System | 17,732 | $14.3K | 0.00% | +2,093+13.4% | Added |
| SG Americas Securities, LLC | 17,206 | $14.0K | 0.00% | +3,467+25.2% | Added |
| Allspring Global Investments Holdings, LLC | 16,175 | $13.1K | 0.00% | 00.0% | Unchanged |
| Worth Venture Partners, LLC | 12,810 | $10.4K | 0.01% | +12,810 | New |
| Tower Research Capital LLC (TRC) | 12,322 | $10.0K | 0.00% | −14,279−53.7% | Reduced |
| Cetera Advisors LLC | 11,194 | $9.06K | 0.00% | 00.0% | Unchanged |
| Quantum Private Wealth, LLC | 10,640 | $8.61K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 10,504 | $8.50K | 0.00% | −136−1.3% | Reduced |
| Zuckerman Investment Group, LLC | 10,479 | $8.48K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 8,508 | $6.88K | 0.00% | +8,508 | New |
| New York State Common Retirement Fund | 5,832 | $4.72K | 0.00% | −20,500−77.9% | Reduced |
| Amalgamated Bank | 4,528 | $4.00K | 0.00% | −160−3.4% | Reduced |
| Legal & General Group Plc | 4,438 | $3.59K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,483 | $2.01K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 2,668 | $2.00K | 0.00% | −2,112−44.2% | Reduced |
| Quantbot Technologies LP | 2,400 | $1.94K | 0.00% | +2,400 | New |
| Citigroup Inc | 1,789 | $1.45K | 0.00% | −267−13.0% | Reduced |
| Cutler Group LP | 2,400 | $1.00K | 0.00% | +700+41.2% | Added |
| Allworth Financial LP | 632 | $512 | 0.00% | +632 | New |
| FMR LLC | 629 | $509 | 0.00% | −3,878−86.0% | Reduced |
| Newbridge Financial Services Group, Inc. | 23 | $19 | 0.00% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −3,518,062−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −1,585,324−100.0% | Sold out |
| Artal Group S.A. | 0 | $0 | 0.00% | −1,200,000−100.0% | Sold out |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −630,584−100.0% | Sold out |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −610,000−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −574,426−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −252,017−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −196,669−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −150,000−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −148,001−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −105,846−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −98,409−100.0% | Sold out |