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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
60
−14 vs. Q3 2023
Shares held
8.02M
+389.3K (+5.1%) vs. Q3 2023Converted for a 1-for-15 split
Total value
$178.6M
−$17.0M (−8.7%) vs. Q3 2023
New holders
10
28 more added
Sold out
24
8 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 60 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ4 2023: $178.6M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2023.

Institutions holding PRAX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Adage Capital Partners GP, L.L.C.738,666$16.5M0.03%+153,333+26.2%AddedConverted for a 1-for-15 split
Verition Fund Management LLC703,000$15.7M0.16%+99,011+16.4%AddedConverted for a 1-for-15 split
Point72 Asset Management, L.P.692,252$15.4M0.05%00.0%UnchangedConverted for a 1-for-15 split
PFM Health Sciences, LP656,548$14.6M0.88%+61,882+10.4%AddedConverted for a 1-for-15 split
Cormorant Asset Management, LP633,345$14.1M0.68%00.0%UnchangedConverted for a 1-for-15 split
Vanguard Group Inc370,938$8.26M0.00%00.0%UnchangedConverted for a 1-for-15 split
VR Adviser, LLC353,626$7.88M0.54%00.0%UnchangedConverted for a 1-for-15 split
Kingdon Capital Management, L.L.C.346,665$7.72M1.47%00.0%UnchangedConverted for a 1-for-15 split
Velan Capital Investment Management LP345,666$7.70M5.45%00.0%UnchangedConverted for a 1-for-15 split
Sphera Funds Management Ltd.328,986$7.33M1.36%+5,632+1.7%AddedConverted for a 1-for-15 split
Acuta Capital Partners, LLC299,636$6.68M3.76%00.0%UnchangedConverted for a 1-for-15 split
Silverarc Capital Management, LLC283,841$6.32M1.95%+9,313+3.4%AddedConverted for a 1-for-15 split
Bank of America Corp278,862$6.21M0.00%00.0%UnchangedConverted for a 1-for-15 split
Tri Locum Partners LP248,761$5.54M2.72%−74,958−23.2%ReducedConverted for a 1-for-15 split
Ikarian Capital, LLC200,000$4.46M1.22%+50,000+33.3%AddedConverted for a 1-for-15 split
CIBC Asset Management Inc173,868$3.87M0.01%+52,141+42.8%AddedConverted for a 1-for-15 split
Baker Bros. Advisors LP131,533$2.93M0.03%+6,205+5.0%AddedConverted for a 1-for-15 split
BlackRock Inc.126,536$2.82M0.00%+1,546+1.2%AddedConverted for a 1-for-15 split
Acadian Asset Management LLC98,049$2.18M0.01%+2,417+2.5%AddedConverted for a 1-for-15 split
Geode Capital Management, LLC92,958$2.07M0.00%+6,412+7.4%AddedConverted for a 1-for-15 split
Renaissance Technologies LLC80,804$1.80M0.00%+15,671+24.1%AddedConverted for a 1-for-15 split
Ally Bridge Group (NY) LLC70,424$1.57M1.13%00.0%UnchangedConverted for a 1-for-15 split
Blackstone Group Inc.70,273$1.57M0.01%00.0%UnchangedConverted for a 1-for-15 split
Jacobs Levy Equity Management, Inc66,488$1.48M0.01%+20,929+45.9%AddedConverted for a 1-for-15 split
72 Investment Holdings, LLC65,933$1.47M6.52%00.0%UnchangedConverted for a 1-for-15 split
Citadel Advisors LLC56,479$1.26M0.00%+15,243+37.0%AddedConverted for a 1-for-15 split
Marshall Wace, LLP48,842$1.09M0.00%+7,064+16.9%AddedConverted for a 1-for-15 split
Susquehanna International Group, LLP48,284$1.08M0.00%+34,499+250.3%AddedConverted for a 1-for-15 split
Boothbay Fund Management, LLC46,710$1.04M0.04%+16,500+54.6%AddedConverted for a 1-for-15 split
State Street Corp30,708$684.2K0.00%+16,938+123.0%AddedConverted for a 1-for-15 split
Atom Investors LP30,037$669.2K0.12%+23,185+338.4%AddedConverted for a 1-for-15 split
Qube Research & Technologies Ltd25,104$559.3K0.00%+25,082+113,664.4%AddedConverted for a 1-for-15 split
Citigroup Inc23,524$524.1K0.00%+17,983+324.5%AddedConverted for a 1-for-15 split
Millennium Management LLC22,346$497.9K0.00%+10,179+83.7%AddedConverted for a 1-for-15 split
UBS Oconnor LLC22,278$496.4K0.02%−16,625−42.7%ReducedConverted for a 1-for-15 split
Bridgeway Capital Management, LLC21,152$471.3K0.01%+7,705+57.3%AddedConverted for a 1-for-15 split
Northern Trust Corp19,364$431.4K0.00%−370−1.9%ReducedConverted for a 1-for-15 split
J. Goldman & Co LP18,000$401.0K0.02%00.0%UnchangedConverted for a 1-for-15 split
Morgan Stanley16,933$377.3K0.00%−2,415−12.5%ReducedConverted for a 1-for-15 split
Wildcat Capital Management, LLC16,756$373.3K0.13%+16,756New
Victory Capital Management Inc15,705$349.9K0.00%+14,867+1,774.4%AddedConverted for a 1-for-15 split
Dimensional Fund Advisors LP13,710$305.1K0.00%+12,302+873.8%AddedConverted for a 1-for-15 split
Man Group plc13,139$292.7K0.00%+13,139New
Connor, Clark & Lunn Investment Management Ltd.11,531$256.9K0.00%+7,789+208.2%AddedConverted for a 1-for-15 split
683 Capital Management, LLC11,481$255.8K0.03%+11,481New
Jane Street Group, LLC10,576$235.6K0.00%+10,576New
DLD Asset Management, LP10,000$222.8K0.04%+10,000New
Two Sigma Investments, LP9,426$210.0K0.00%+5,633+148.5%AddedConverted for a 1-for-15 split
Barclays PLC9,245$206.0K0.00%+9,245New
UBS Group AG2,699$60.1K0.00%+2,699New
Simplex Trading, LLC1,392$31.0K0.00%+1,392New
Royal Bank of Canada1,157$26.0K0.00%+1,157New
Farther Finance Advisors, LLC1,000$22.3K0.00%00.0%UnchangedConverted for a 1-for-15 split
Group One Trading, L.P.160$3.56K0.00%−17−9.4%ReducedConverted for a 1-for-15 split
Deutsche Bank AG152$3.39K0.00%−1−0.6%ReducedConverted for a 1-for-15 split
Rhumbline Advisers152$3.39K0.00%00.0%UnchangedConverted for a 1-for-15 split
FMR LLC115$2.56K0.00%−13−10.5%ReducedConverted for a 1-for-15 split
Wells Fargo & Company67$1.49K0.00%+4+7.1%AddedConverted for a 1-for-15 split
JPMorgan Chase & Co17$3790.00%−81−82.6%ReducedConverted for a 1-for-15 split
FSA Wealth Management LLC21$00.00%+21New
Vida Ventures Advisors, LLC0$00.00%−97,978−100.0%Sold outConverted for a 1-for-15 split
Soleus Capital Management, L.P.0$00.00%−76,667−100.0%Sold outConverted for a 1-for-15 split
Altium Capital Management LP0$00.00%−43,333−100.0%Sold outConverted for a 1-for-15 split
Schonfeld Strategic Advisors LLC0$00.00%−42,170−100.0%Sold outConverted for a 1-for-15 split
Goldman Sachs Group Inc0$00.00%−6,174−100.0%Sold outConverted for a 1-for-15 split
Bank of New York Mellon Corp0$00.00%−5,005−100.0%Sold outConverted for a 1-for-15 split
PEAK6 Investments LLC0$00.00%−4,298−100.0%Sold outConverted for a 1-for-15 split
Principal Financial Group Inc0$00.00%−2,310−100.0%Sold outConverted for a 1-for-15 split
Gsa Capital Partners LLP0$00.00%−2,237−100.0%Sold outConverted for a 1-for-15 split
Jump Financial, LLC0$00.00%−2,177−100.0%Sold outConverted for a 1-for-15 split
Alta Wealth Advisors LLC0$00.00%−2,069−100.0%Sold outConverted for a 1-for-15 split
PCG Wealth Advisors, LLC0$00.00%−1,967−100.0%Sold outConverted for a 1-for-15 split
Charles Schwab Investment Management Inc0$00.00%−1,410−100.0%Sold outConverted for a 1-for-15 split
Prudential Financial Inc0$00.00%−1,113−100.0%Sold outConverted for a 1-for-15 split
Neuberger Berman Group LLC0$00.00%−1,071−100.0%Sold outConverted for a 1-for-15 split
Two Sigma Advisers, LP0$00.00%−1,047−100.0%Sold outConverted for a 1-for-15 split
Cetera Advisors LLC0$00.00%−746−100.0%Sold outConverted for a 1-for-15 split
Zuckerman Investment Group, LLC0$00.00%−699−100.0%Sold outConverted for a 1-for-15 split
Quantum Private Wealth, LLC0$00.00%−693−100.0%Sold outConverted for a 1-for-15 split
GWM Advisors LLC0$00.00%−208−100.0%Sold outConverted for a 1-for-15 split
Cutler Group LP0$00.00%−160−100.0%Sold outConverted for a 1-for-15 split
IFP Advisors, Inc0$00.00%−33−100.0%Sold outConverted for a 1-for-15 split
Toronto Dominion Bank0$00.00%−27−100.0%Sold outConverted for a 1-for-15 split
Newbridge Financial Services Group, Inc.0$00.00%−2−100.0%Sold outConverted for a 1-for-15 split