Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 150
- −11 vs. Q4 2024
- Shares held
- 23.5M
- +2.04M (+9.5%) vs. Q4 2024
- Total value
- $889.3M
- −$758.8M (−46.0%) vs. Q4 2024
- New holders
- 34
- 47 more added
- Sold out
- 45
- 52 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cormorant Asset Management, LP | 1,745,000 | $66.1M | 5.00% | +51,781+3.1% | Added |
| Adage Capital Partners GP, L.L.C. | 1,742,758 | $66.0M | 0.12% | +1,137,748+188.1% | Added |
| Janus Henderson Group PLC | 1,506,436 | $58.3M | 0.03% | +576,913+62.1% | Added |
| BlackRock, Inc. | 1,416,935 | $53.7M | 0.00% | −45,510−3.1% | Reduced |
| Morgan Stanley | 1,213,669 | $46.0M | 0.00% | +50,143+4.3% | Added |
| Soleus Capital Management, L.P. | 1,139,740 | $43.2M | 3.38% | +896,200+368.0% | Added |
| Price T Rowe Associates Inc | 1,095,725 | $41.5M | 0.01% | −112,797−9.3% | Reduced |
| Vanguard Group Inc | 1,087,020 | $41.2M | 0.00% | +23,381+2.2% | Added |
| VR Adviser, LLC | 989,985 | $37.5M | 3.19% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 980,894 | $37.1M | 1.32% | −348,841−26.2% | Reduced |
| Capital Research Global Investors | 853,746 | $32.3M | 0.01% | −139,823−14.1% | Reduced |
| State Street Corp | 737,039 | $27.9M | 0.00% | −31,616−4.1% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 619,931 | $23.5M | 0.47% | +619,931 | New |
| Assenagon Asset Management S.A. | 507,400 | $19.2M | 0.03% | −51,682−9.2% | Reduced |
| Driehaus Capital Management LLC | 481,598 | $18.2M | 0.18% | +316,686+192.0% | Added |
| Bank of America Corp | 460,707 | $17.4M | 0.00% | +455,203+8,270.4% | Added |
| Geode Capital Management, LLC | 418,016 | $15.8M | 0.00% | +11,305+2.8% | Added |
| Balyasny Asset Management LLC | 403,003 | $15.3M | 0.04% | +403,003 | New |
| CIBC Asset Management Inc | 388,759 | $14.7M | 0.05% | +22,003+6.0% | Added |
| Point72 Asset Management, L.P. | 333,534 | $12.6M | 0.04% | −187,739−36.0% | Reduced |
| Baker Bros. Advisors LP | 331,533 | $12.6M | 0.14% | 00.0% | Unchanged |
| Franklin Resources Inc | 314,127 | $11.9M | 0.00% | −75,708−19.4% | Reduced |
| Verition Fund Management LLC | 199,657 | $7.56M | 0.04% | −264,851−57.0% | Reduced |
| UBS Group AG | 192,909 | $7.31M | 0.00% | +72,642+60.4% | Added |
| Velan Capital Investment Management LP | 185,000 | $7.01M | 7.21% | −115,000−38.3% | Reduced |
| Goldman Sachs Group Inc | 177,264 | $6.71M | 0.00% | −102,131−36.6% | Reduced |
| Woodline Partners LP | 175,727 | $6.65M | 0.04% | +165,779+1,666.5% | Added |
| 5AM Venture Management, LLC | 170,000 | $6.44M | 2.43% | 00.0% | Unchanged |
| Silverarc Capital Management, LLC | 166,074 | $6.29M | 1.31% | +93,558+129.0% | Added |
| Northern Trust Corp | 165,183 | $6.26M | 0.00% | −2,407−1.4% | Reduced |
| PFM Health Sciences, LP | 160,866 | $6.09M | 0.47% | +41,357+34.6% | Added |
| Sofinnova Investments, Inc. | 157,640 | $5.97M | 0.45% | +157,640 | New |
| Alyeska Investment Group, L.P. | 150,000 | $5.68M | 0.02% | −76,788−33.9% | Reduced |
| Ikarian Capital, LLC | 145,502 | $5.51M | 1.80% | +145,502 | New |
| Charles Schwab Investment Management Inc | 141,080 | $5.34M | 0.00% | −1,812−1.3% | Reduced |
| Sphera Funds Management Ltd. | 140,660 | $5.33M | 1.31% | +49,077+53.6% | Added |
| Walleye Capital LLC | 131,756 | $4.99M | 0.06% | +42,143+47.0% | Added |
| Sio Capital Management, LLC | 112,500 | $4.26M | 1.29% | +112,500 | New |
| Ally Bridge Group (NY) LLC | 95,582 | $3.62M | 3.26% | +50,600+112.5% | Added |
| Standard Life Aberdeen plc | 87,903 | $3.33M | 0.01% | +82,904+1,658.4% | Added |
| Acuta Capital Partners, LLC | 87,141 | $3.30M | 3.83% | +19,641+29.1% | Added |
| UBS Asset Management Americas Inc | 87,081 | $3.30M | 0.00% | +68,466+367.8% | Added |
| Norges Bank | 84,200 | $3.19M | 0.00% | −34,700−29.2% | Reduced |
| Tri Locum Partners LP | 83,659 | $3.17M | 1.63% | +46,390+124.5% | Added |
| Pictet Asset Management Holding SA | 78,588 | $2.98M | 0.00% | +33,161+73.0% | Added |
| First Turn Management, LLC | 71,775 | $2.72M | 0.55% | +26,239+57.6% | Added |
| Millennium Management LLC | 69,181 | $2.62M | 0.00% | −81,711−54.2% | Reduced |
| 72 Investment Holdings, LLC | 65,933 | $2.50M | 7.02% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 65,265 | $2.47M | 0.06% | +65,265 | New |
| Candriam Luxembourg S.C.A. | 63,671 | $2.41M | 0.02% | −54,299−46.0% | Reduced |
| Citadel Advisors LLC | 62,210 | $2.36M | 0.00% | −30,980−33.2% | Reduced |
| Alliancebernstein L.P. | 51,116 | $1.94M | 0.00% | −27,511−35.0% | Reduced |
| Wellington Management Group LLP | 50,776 | $1.92M | 0.00% | −13,158−20.6% | Reduced |
| Boothbay Fund Management, LLC | 46,626 | $1.77M | 0.06% | +46,626 | New |
| Bank of New York Mellon Corp | 46,307 | $1.75M | 0.00% | −549−1.2% | Reduced |
| Citigroup Inc | 45,632 | $1.73M | 0.00% | −49,415−52.0% | Reduced |
| Jacobs Levy Equity Management, Inc | 39,999 | $1.51M | 0.01% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 39,975 | $1.51M | 0.02% | +39,975 | New |
| HighVista Strategies LLC | 39,286 | $1.49M | 0.57% | +28,335+258.7% | Added |
| TD Asset Management Inc | 37,138 | $1.41M | 0.00% | −15,760−29.8% | Reduced |
| FMR LLC | 35,719 | $1.35M | 0.00% | −152,648−81.0% | Reduced |
| Susquehanna International Group, LLP | 34,748 | $1.32M | 0.00% | −123,177−78.0% | Reduced |
| Manufacturers Life Insurance Company, The | 32,492 | $1.23M | 0.00% | −5,991−15.6% | Reduced |
| Barclays PLC | 31,768 | $1.20M | 0.00% | −5,520−14.8% | Reduced |
| Moody Aldrich Partners LLC | 30,221 | $1.14M | 0.24% | −456−1.5% | Reduced |
| Rafferty Asset Management, LLC | 29,245 | $1.11M | 0.00% | −4,384−13.0% | Reduced |
| Swiss National Bank | 27,100 | $1.03M | 0.00% | +1,000+3.8% | Added |
| UBS Oconnor LLC | 26,793 | $1.01M | 0.02% | +290+1.1% | Added |
| Rhumbline Advisers | 24,294 | $920.0K | 0.00% | +1,525+6.7% | Added |
| Algert Global LLC | 21,490 | $813.8K | 0.02% | +21,490 | New |
| Atom Investors LP | 19,779 | $749.0K | 0.09% | +19,779 | New |
| B Group, Inc. | 19,000 | $719.5K | 0.63% | +19,000 | New |
| Two Sigma Investments, LP | 18,808 | $712.3K | 0.00% | −1,258−6.3% | Reduced |
| Caption Management, LLC | 18,280 | $692.3K | 0.03% | +18,280 | New |
| PCG Wealth Advisors, LLC | 16,413 | $621.6K | 0.22% | −869−5.0% | Reduced |
| California State Teachers Retirement System | 16,346 | $619.0K | 0.00% | +3,620+28.4% | Added |
| Alps Advisors Inc | 14,938 | $565.7K | 0.00% | −128−0.8% | Reduced |
| State of Wisconsin Investment Board | 14,611 | $553.3K | 0.00% | +3,929+36.8% | Added |
| Legal & General Group Plc | 14,409 | $545.7K | 0.00% | −30−0.2% | Reduced |
| Deutsche Bank AG | 13,861 | $524.9K | 0.00% | −1,463−9.5% | Reduced |
| Gsa Capital Partners LLP | 12,977 | $491.0K | 0.04% | +7,295+128.4% | Added |
| D. E. Shaw & Co., Inc. | 12,208 | $462.3K | 0.00% | −35,785−74.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 11,708 | $444.5K | 0.00% | +573+5.1% | Added |
| Invesco Ltd. | 11,678 | $442.2K | 0.00% | −75,305−86.6% | Reduced |
| JPMorgan Chase & Co | 11,479 | $434.7K | 0.00% | +1,786+18.4% | Added |
| Group One Trading, L.P. | 10,927 | $413.8K | 0.02% | +10,927 | New |
| MetLife Investment Management | 10,597 | $401.3K | 0.00% | −78−0.7% | Reduced |
| Hussman Strategic Advisors, Inc. | 10,500 | $397.6K | 0.10% | 00.0% | Unchanged |
| XTX Topco Ltd | 10,043 | $380.3K | 0.02% | +10,043 | New |
| Nuveen, LLC | 14,762 | $376.6K | 0.00% | +14,762 | New |
| Jane Street Group, LLC | 9,489 | $359.3K | 0.00% | −27,655−74.5% | Reduced |
| Intech Investment Management LLC | 8,798 | $333.2K | 0.00% | +2,460+38.8% | Added |
| Wells Fargo & Company | 8,517 | $322.5K | 0.00% | −95−1.1% | Reduced |
| Corebridge Financial, Inc. | 8,448 | $319.9K | 0.00% | −126−1.5% | Reduced |
| LMR Partners LLP | 7,774 | $294.4K | 0.01% | +7,774 | New |
| Engineers Gate Manager LP | 7,606 | $288.0K | 0.00% | +3,756+97.6% | Added |
| BNP Paribas Arbitrage, SA | 7,451 | $282.2K | 0.00% | +5,309+247.9% | Added |
| New York State Common Retirement Fund | 6,600 | $249.9K | 0.00% | −1,247−15.9% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 6,250 | $236.7K | 0.02% | +6,250 | New |
| Profund Advisors LLC | 6,108 | $231.3K | 0.01% | −451−6.9% | Reduced |