Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 150
- −11 vs. Q4 2024
- Shares held
- 23.5M
- +2.04M (+9.5%) vs. Q4 2024
- Total value
- $889.3M
- −$758.8M (−46.0%) vs. Q4 2024
- New holders
- 34
- 47 more added
- Sold out
- 45
- 52 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 1 | $0 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 1 | $38 | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 5 | $189 | 0.00% | −20−80.0% | Reduced |
| The PNC Financial Services Group, Inc. | 5 | $189 | 0.00% | +3+150.0% | Added |
| Allworth Financial LP | 6 | $216 | 0.00% | +6 | New |
| Creative Financial Designs Inc | 6 | $227 | 0.00% | +6 | New |
| Parkside Financial Bank & Trust | 10 | $379 | 0.00% | +10 | New |
| Stephens Consulting, LLC | 10 | $379 | 0.00% | +10 | New |
| TD Private Client Wealth LLC | 11 | $417 | 0.00% | +11 | New |
| EverSource Wealth Advisors, LLC | 11 | $417 | 0.00% | +11 | New |
| Principal Securities, Inc. | 6 | $462 | 0.00% | 00.0% | Unchanged |
| Coldstream Capital Management Inc | 13 | $493 | 0.00% | +13 | New |
| UMA Financial Services, Inc. | 17 | $644 | 0.00% | +17 | New |
| Sterling Capital Management LLC | 18 | $682 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 20 | $757 | 0.00% | +17+566.7% | Added |
| FSA Wealth Management LLC | 21 | $795 | 0.00% | 00.0% | Unchanged |
| Hemington Wealth Management | 30 | $1.00K | 0.00% | +30 | New |
| Comerica Bank | 40 | $1.51K | 0.00% | +40 | New |
| Clear Street Markets LLC | 40 | $1.51K | 0.00% | +40 | New |
| Quantbot Technologies LP | 47 | $1.78K | 0.00% | +47 | New |
| Daiwa Securities Group Inc. | 62 | $2.00K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 62 | $2.39K | 0.00% | −55−47.0% | Reduced |
| SBI Securities Co., Ltd. | 65 | $2.46K | 0.00% | +5+8.3% | Added |
| Advisor Group Holdings, Inc. | 66 | $2.50K | 0.00% | −13−16.5% | Reduced |
| CWM, LLC | 77 | $3.00K | 0.00% | −118−60.5% | Reduced |
| Royal Bank of Canada | 108 | $4.00K | 0.00% | −406−79.0% | Reduced |
| GAMMA Investing LLC | 106 | $4.01K | 0.00% | +41+63.1% | Added |
| Quest Partners LLC | 148 | $5.61K | 0.00% | +53+55.8% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 167 | $6.32K | 0.00% | +167 | New |
| Farther Finance Advisors, LLC | 200 | $7.17K | 0.00% | +200 | New |
| Public Employees Retirement Association of Colorado | 217 | $8.00K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 334 | $12.6K | 0.00% | +263+370.4% | Added |
| GF Fund Management Co. Ltd. | 477 | $18.1K | 0.00% | +86+22.0% | Added |
| Amalgamated Bank | 599 | $23.0K | 0.00% | +2+0.3% | Added |
| Mirae Asset Global Investments Co., Ltd. | 675 | $26.1K | 0.00% | +54+8.7% | Added |
| US Bancorp | 866 | $32.8K | 0.00% | −102−10.5% | Reduced |
| Tower Research Capital LLC (TRC) | 1,478 | $56.0K | 0.00% | −4,395−74.8% | Reduced |
| Ameritas Investment Partners, Inc. | 1,689 | $64.0K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 2,316 | $87.7K | 0.02% | +2,316 | New |
| KLP Kapitalforvaltning AS | 2,800 | $106.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 3,004 | $114.0K | 0.00% | +3,004 | New |
| Simplex Trading, LLC | 3,298 | $124.0K | 0.00% | −13,556−80.4% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 3,789 | $143.5K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 3,900 | $147.7K | 0.04% | −300−7.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 4,044 | $153.1K | 0.01% | +92+2.3% | Added |
| Ameriprise Financial Inc | 5,408 | $204.8K | 0.00% | +2,181+67.6% | Added |
| Graham Capital Management, L.P. | 5,449 | $206.4K | 0.01% | +2,727+100.2% | Added |
| Shay Capital LLC | 5,500 | $208.3K | 0.06% | +5,500 | New |
| State Board of Administration of Florida Retirement System | 6,040 | $228.7K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 6,074 | $230.0K | 0.00% | −37,026−85.9% | Reduced |
| Profund Advisors LLC | 6,108 | $231.3K | 0.01% | −451−6.9% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 6,250 | $236.7K | 0.02% | +6,250 | New |
| New York State Common Retirement Fund | 6,600 | $249.9K | 0.00% | −1,247−15.9% | Reduced |
| BNP Paribas Arbitrage, SA | 7,451 | $282.2K | 0.00% | +5,309+247.9% | Added |
| Engineers Gate Manager LP | 7,606 | $288.0K | 0.00% | +3,756+97.6% | Added |
| LMR Partners LLP | 7,774 | $294.4K | 0.01% | +7,774 | New |
| Corebridge Financial, Inc. | 8,448 | $319.9K | 0.00% | −126−1.5% | Reduced |
| Wells Fargo & Company | 8,517 | $322.5K | 0.00% | −95−1.1% | Reduced |
| Intech Investment Management LLC | 8,798 | $333.2K | 0.00% | +2,460+38.8% | Added |
| Jane Street Group, LLC | 9,489 | $359.3K | 0.00% | −27,655−74.5% | Reduced |
| Nuveen, LLC | 14,762 | $376.6K | 0.00% | +14,762 | New |
| XTX Topco Ltd | 10,043 | $380.3K | 0.02% | +10,043 | New |
| Hussman Strategic Advisors, Inc. | 10,500 | $397.6K | 0.10% | 00.0% | Unchanged |
| MetLife Investment Management | 10,597 | $401.3K | 0.00% | −78−0.7% | Reduced |
| Group One Trading, L.P. | 10,927 | $413.8K | 0.02% | +10,927 | New |
| JPMorgan Chase & Co | 11,479 | $434.7K | 0.00% | +1,786+18.4% | Added |
| Invesco Ltd. | 11,678 | $442.2K | 0.00% | −75,305−86.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 11,708 | $444.5K | 0.00% | +573+5.1% | Added |
| D. E. Shaw & Co., Inc. | 12,208 | $462.3K | 0.00% | −35,785−74.6% | Reduced |
| Gsa Capital Partners LLP | 12,977 | $491.0K | 0.04% | +7,295+128.4% | Added |
| Deutsche Bank AG | 13,861 | $524.9K | 0.00% | −1,463−9.5% | Reduced |
| Legal & General Group Plc | 14,409 | $545.7K | 0.00% | −30−0.2% | Reduced |
| State of Wisconsin Investment Board | 14,611 | $553.3K | 0.00% | +3,929+36.8% | Added |
| Alps Advisors Inc | 14,938 | $565.7K | 0.00% | −128−0.8% | Reduced |
| California State Teachers Retirement System | 16,346 | $619.0K | 0.00% | +3,620+28.4% | Added |
| PCG Wealth Advisors, LLC | 16,413 | $621.6K | 0.22% | −869−5.0% | Reduced |
| Caption Management, LLC | 18,280 | $692.3K | 0.03% | +18,280 | New |
| Two Sigma Investments, LP | 18,808 | $712.3K | 0.00% | −1,258−6.3% | Reduced |
| B Group, Inc. | 19,000 | $719.5K | 0.63% | +19,000 | New |
| Atom Investors LP | 19,779 | $749.0K | 0.09% | +19,779 | New |
| Algert Global LLC | 21,490 | $813.8K | 0.02% | +21,490 | New |
| Rhumbline Advisers | 24,294 | $920.0K | 0.00% | +1,525+6.7% | Added |
| UBS Oconnor LLC | 26,793 | $1.01M | 0.02% | +290+1.1% | Added |
| Swiss National Bank | 27,100 | $1.03M | 0.00% | +1,000+3.8% | Added |
| Rafferty Asset Management, LLC | 29,245 | $1.11M | 0.00% | −4,384−13.0% | Reduced |
| Moody Aldrich Partners LLC | 30,221 | $1.14M | 0.24% | −456−1.5% | Reduced |
| Barclays PLC | 31,768 | $1.20M | 0.00% | −5,520−14.8% | Reduced |
| Manufacturers Life Insurance Company, The | 32,492 | $1.23M | 0.00% | −5,991−15.6% | Reduced |
| Susquehanna International Group, LLP | 34,748 | $1.32M | 0.00% | −123,177−78.0% | Reduced |
| FMR LLC | 35,719 | $1.35M | 0.00% | −152,648−81.0% | Reduced |
| TD Asset Management Inc | 37,138 | $1.41M | 0.00% | −15,760−29.8% | Reduced |
| HighVista Strategies LLC | 39,286 | $1.49M | 0.57% | +28,335+258.7% | Added |
| ExodusPoint Capital Management, LP | 39,975 | $1.51M | 0.02% | +39,975 | New |
| Jacobs Levy Equity Management, Inc | 39,999 | $1.51M | 0.01% | 00.0% | Unchanged |
| Citigroup Inc | 45,632 | $1.73M | 0.00% | −49,415−52.0% | Reduced |
| Bank of New York Mellon Corp | 46,307 | $1.75M | 0.00% | −549−1.2% | Reduced |
| Boothbay Fund Management, LLC | 46,626 | $1.77M | 0.06% | +46,626 | New |
| Wellington Management Group LLP | 50,776 | $1.92M | 0.00% | −13,158−20.6% | Reduced |
| Alliancebernstein L.P. | 51,116 | $1.94M | 0.00% | −27,511−35.0% | Reduced |
| Citadel Advisors LLC | 62,210 | $2.36M | 0.00% | −30,980−33.2% | Reduced |