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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
74
−3 vs. Q2 2023
Shares held
114.4M
−2.60M (−2.2%) vs. Q2 2023
Total value
$195.6M
+$61.1M (+45.4%) vs. Q2 2023
New holders
11
21 more added
Sold out
14
20 more reduced

1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 74 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ3 2023: $195.6M
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2023.

Institutions holding PRAX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Point72 Asset Management, L.P.10,383,780$17.8M0.06%−166,220−1.6%Reduced
Cormorant Asset Management, LP9,500,000$16.2M0.95%00.0%Unchanged
Verition Fund Management LLC9,059,839$15.5M0.21%−1,427,989−13.6%Reduced
PFM Health Sciences, LP8,919,997$15.3M0.73%+28,235+0.3%Added
Adage Capital Partners GP, L.L.C.8,780,000$15.0M0.03%+849,362+10.7%Added
Vanguard Group Inc5,564,114$9.51M0.00%+3,199,541+135.3%Added
VR Adviser, LLC5,304,410$9.07M0.95%00.0%Unchanged
Kingdon Capital Management, L.L.C.5,200,000$8.89M1.63%00.0%Unchanged
Velan Capital Investment Management LP5,185,000$8.87M7.25%00.0%Unchanged
Tri Locum Partners LP4,855,783$8.30M2.66%−28,838−0.6%Reduced
Sphera Funds Management Ltd.4,850,317$8.29M1.99%−3,914,017−44.7%Reduced
Acuta Capital Partners, LLC4,485,000$7.67M5.58%+235,000+5.5%Added
Bank of America Corp4,171,107$7.13M0.00%−281,067−6.3%Reduced
Silverarc Capital Management, LLC4,117,920$7.04M2.62%+641,758+18.5%Added
Ikarian Capital, LLC2,250,000$3.85M1.43%+2,250,000New
Baker Bros. Advisors LP1,879,915$3.21M0.02%00.0%Unchanged
BlackRock Inc.1,874,843$3.21M0.00%+1,270,920+210.4%Added
CIBC Asset Management Inc1,825,910$3.12M0.01%+295,425+19.3%Added
Vida Ventures Advisors, LLC1,469,665$2.51M3.89%00.0%Unchanged
Acadian Asset Management LLC1,434,474$2.45M0.01%−108,743−7.0%Reduced
Geode Capital Management, LLC1,298,186$2.22M0.00%+854,896+192.9%Added
Soleus Capital Management, L.P.1,150,000$1.97M0.20%−950,000−45.2%Reduced
Ally Bridge Group (NY) LLC1,056,370$1.81M2.12%−2,143,630−67.0%Reduced
Blackstone Group Inc.1,054,109$1.80M0.01%00.0%Unchanged
72 Investment Holdings, LLC988,995$1.69M11.33%00.0%Unchanged
Renaissance Technologies LLC977,000$1.67M0.00%+321,200+49.0%Added
Jacobs Levy Equity Management, Inc683,379$1.17M0.01%−624,145−47.7%Reduced
Altium Capital Management LP650,000$1.11M0.64%−775,000−54.4%Reduced
Schonfeld Strategic Advisors LLC632,543$1.08M0.01%−87,226−12.1%Reduced
Marshall Wace, LLP626,669$1.07M0.00%+626,669New
Citadel Advisors LLC618,540$1.06M0.00%−40,669−6.2%Reduced
UBS Oconnor LLC583,544$997.9K0.02%00.0%Unchanged
Boothbay Fund Management, LLC453,150$774.9K0.03%+453,150New
Northern Trust Corp296,009$506.2K0.00%+175,511+145.7%Added
Morgan Stanley290,213$496.3K0.00%+47,217+19.4%Added
J. Goldman & Co LP270,000$461.7K0.02%00.0%Unchanged
Susquehanna International Group, LLP206,770$353.6K0.00%+55,123+36.3%Added
State Street Corp206,555$353.2K0.00%−4,050−1.9%Reduced
Bridgeway Capital Management, LLC201,700$344.9K0.01%+100,000+98.3%Added
Millennium Management LLC182,499$312.1K0.00%−1,065,266−85.4%Reduced
Atom Investors LP102,779$175.8K0.04%+102,779New
Goldman Sachs Group Inc92,613$158.4K0.00%−60,918−39.7%Reduced
Citigroup Inc83,115$142.1K0.00%+82,929+44,585.5%Added
Bank of New York Mellon Corp75,077$128.4K0.00%+60,342+409.5%Added
PEAK6 Investments LLC64,468$110.2K0.01%−10,000−13.4%Reduced
Two Sigma Investments, LP56,900$97.3K0.00%+44,800+370.2%Added
Connor, Clark & Lunn Investment Management Ltd.56,130$96.0K0.00%+17,428+45.0%Added
Principal Financial Group Inc34,652$59.3K0.00%+2,881+9.1%Added
Gsa Capital Partners LLP33,549$57.0K0.00%+21,250+172.8%Added
Jump Financial, LLC32,659$55.8K0.00%+32,659New
Alta Wealth Advisors LLC31,028$53.1K0.03%00.0%Unchanged
PCG Wealth Advisors, LLC29,500$50.4K0.03%+29,500New
Charles Schwab Investment Management Inc21,152$36.2K0.00%00.0%Unchanged
Dimensional Fund Advisors LP21,118$36.1K0.00%00.0%Unchanged
Prudential Financial Inc16,700$28.6K0.00%+16,700New
Neuberger Berman Group LLC16,071$27.5K0.00%00.0%Unchanged
Two Sigma Advisers, LP15,700$26.8K0.00%−9,100−36.7%Reduced
Farther Finance Advisors, LLC15,000$25.6K0.00%+15,000New
Victory Capital Management Inc12,568$21.5K0.00%+12,568New
Cetera Advisors LLC11,194$19.1K0.00%00.0%Unchanged
Zuckerman Investment Group, LLC10,479$17.9K0.00%00.0%Unchanged
Quantum Private Wealth, LLC10,393$17.8K0.01%00.0%Unchanged
GWM Advisors LLC3,122$5.34K0.00%+3,122New
Group One Trading, L.P.2,649$4.53K0.00%+2,470+1,379.9%Added
Cutler Group LP2,400$4.00K0.00%00.0%Unchanged
Deutsche Bank AG2,294$3.92K0.00%00.0%Unchanged
Rhumbline Advisers2,285$3.91K0.00%−1,314−36.5%Reduced
FMR LLC1,927$3.29K0.00%−1,825−48.6%Reduced
JPMorgan Chase & Co1,465$2.50K0.00%00.0%Unchanged
Wells Fargo & Company938$1.60K0.00%+576+159.1%Added
IFP Advisors, Inc500$8550.00%+500New
Toronto Dominion Bank400$6840.00%00.0%Unchanged
Qube Research & Technologies Ltd331$5660.00%−75,411−99.6%Reduced
Newbridge Financial Services Group, Inc.23$390.00%00.0%Unchanged
Maven Securities LTD0$00.00%−1,351,442−100.0%Sold out
Harvard Management Co Inc0$00.00%−692,617−100.0%Sold out
Federated Hermes, Inc.0$00.00%−365,690−100.0%Sold out
CVI Holdings, LLC0$00.00%−89,174−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−67,177−100.0%Sold out
Old Mission Capital LLC0$00.00%−25,040−100.0%Sold out
Engineers Gate Manager LP0$00.00%−19,492−100.0%Sold out
XTX Topco Ltd0$00.00%−18,130−100.0%Sold out
Ergoteles LLC0$00.00%−15,167−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−11,183−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−10,315−100.0%Sold out
UBS Group AG0$00.00%−7,620−100.0%Sold out
Allworth Financial LP0$00.00%−632−100.0%Sold out
New York State Common Retirement Fund0$00.00%−327−100.0%Sold out
Tekla Capital Management LLC––––Not filed