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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
162
+28 vs. Q3 2024
Shares held
21.7M
+2.85M (+15.1%) vs. Q3 2024
Total value
$1.67B
+$580.5M (+53.2%) vs. Q3 2024
New holders
38
56 more added
Sold out
10
52 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 162 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ4 2024: $1.67B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2024.

Institutions holding PRAX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC2$00.00%00.0%Unchanged
Covestor Ltd1$00.00%+1New
IFP Advisors, Inc1$770.00%+1New
The PNC Financial Services Group, Inc.2$1540.00%+2New
Parallel Advisors, LLC2$1540.00%+2New
CoreCap Advisors, LLC3$2310.00%+3New
Principal Securities, Inc.6$4620.00%00.0%Unchanged
Assetmark, Inc7$5390.00%+7New
Lindbrook Capital, LLC11$8470.00%00.0%Unchanged
Sterling Capital Management LLC18$1.39K0.00%00.0%Unchanged
FSA Wealth Management LLC21$1.62K0.00%00.0%Unchanged
True Wealth Design, LLC25$1.92K0.00%00.0%Unchanged
Rothschild Investment LLC25$1.92K0.00%+10+66.7%Added
Bessemer Group Inc25$2.00K0.00%00.0%Unchanged
SBI Securities Co., Ltd.60$4.62K0.00%+60New
Daiwa Securities Group Inc.62$5.00K0.00%+62New
GAMMA Investing LLC65$5.00K0.00%+39+150.0%Added
Nisa Investment Advisors, LLC71$5.46K0.00%+13+22.4%Added
Advisor Group Holdings, Inc.79$6.08K0.00%+18+29.5%Added
R Squared Ltd90$6.93K0.01%+90New
Quest Partners LLC95$7.31K0.00%+95New
Creative Planning106$8.16K0.00%+106New
Aster Capital Management (DIFC) Ltd117$9.00K0.00%+108+1,200.0%Added
Russell Investments Group, Ltd.156$12.0K0.00%−1,727−91.7%Reduced
CWM, LLC195$15.0K0.00%+17+9.6%Added
Public Employees Retirement Association of Colorado217$17.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.391$30.1K0.00%+391New
Royal Bank of Canada514$39.0K0.00%−1,464−74.0%Reduced
Amalgamated Bank597$46.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.621$47.8K0.00%+621New
US Bancorp968$74.5K0.00%−1,321−57.7%Reduced
Virtus ETF Advisers LLC1,001$77.0K0.03%−1,296−56.4%Reduced
Ameritas Investment Partners, Inc.1,689$130.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA2,142$164.8K0.00%−7,383−77.5%Reduced
Graham Capital Management, L.P.2,722$209.5K0.01%+2,722New
KLP Kapitalforvaltning AS2,800$215.5K0.00%+2,800New
Man Group plc2,832$218.0K0.00%−1,209−29.9%Reduced
Envestnet Asset Management Inc3,008$231.5K0.00%+3,008New
Freestone Grove Partners LP3,080$237.0K0.00%+3,080New
Fox Run Management, L.L.C.3,195$245.9K0.04%+3,195New
Ameriprise Financial Inc3,227$248.3K0.00%+3,227New
Pale Fire Capital SE3,369$259.3K0.06%−63,915−95.0%Reduced
Police & Firemen's Retirement System of New Jersey3,789$291.6K0.00%+3,789New
Glenmede Trust Co NA3,809$293.1K0.00%−364−8.7%Reduced
Coastal Bridge Advisors, LLC3,846$296.0K0.07%00.0%Unchanged
Engineers Gate Manager LP3,850$296.3K0.01%−887−18.7%Reduced
Arizona State Retirement System3,851$296.4K0.00%+156+4.2%Added
China Universal Asset Management Co., Ltd.3,952$304.1K0.03%+3,952New
Teacher Retirement System of Texas3,961$305.0K0.00%+3,961New
Mesirow Financial Investment Management, Inc.4,047$311.5K0.01%+41+1.0%Added
Nomura Holdings Inc4,102$315.7K0.00%+4,102New
Quarry LP4,200$323.2K0.06%+3,200+320.0%Added
Cerity Partners LLC4,364$333.9K0.00%−24−0.5%Reduced
Dimensional Fund Advisors LP4,544$349.7K0.00%−545−10.7%Reduced
SEI Investments Co4,918$378.5K0.00%+29+0.6%Added
Standard Life Aberdeen plc4,999$384.7K0.00%00.0%Unchanged
Maven Securities LTD5,000$384.8K0.06%+5,000New
Voya Investment Management LLC5,228$402.3K0.00%−441−7.8%Reduced
Bank of America Corp5,504$423.6K0.00%−44,345−89.0%Reduced
Gsa Capital Partners LLP5,682$437.0K0.03%+5,682New
ProShare Advisors LLC5,738$441.6K0.00%+5,738New
Tower Research Capital LLC (TRC)5,873$452.0K0.01%+4,990+565.1%Added
State Board of Administration of Florida Retirement System6,040$464.8K0.00%−230−3.7%Reduced
Intech Investment Management LLC6,338$487.8K0.00%+2,567+68.1%Added
Profund Advisors LLC6,559$504.8K0.02%−488−6.9%Reduced
AQR Capital Management LLC6,704$515.9K0.00%−18,564−73.5%Reduced
Squarepoint Ops LLC7,782$598.9K0.00%−6,876−46.9%Reduced
New York State Common Retirement Fund7,847$603.9K0.00%+847+12.1%Added
Ellsworth Advisors, LLC8,150$627.2K0.16%+8,150New
Nicholas Investment Partners, LP8,481$652.7K0.06%+8,481New
Corebridge Financial, Inc.8,574$659.9K0.00%−646−7.0%Reduced
Wells Fargo & Company8,612$662.8K0.00%+2,746+46.8%Added
Trexquant Investment LP9,115$701.5K0.01%−6,317−40.9%Reduced
Fred Alger Management, LLC9,496$730.8K0.00%−927−8.9%Reduced
JPMorgan Chase & Co9,693$746.0K0.00%+1,879+24.0%Added
Woodline Partners LP9,948$765.6K0.01%+9,948New
Hussman Strategic Advisors, Inc.10,500$808.1K0.24%−10,500−50.0%Reduced
MetLife Investment Management10,675$821.5K0.00%+544+5.4%Added
State of Wisconsin Investment Board10,682$822.1K0.00%−1,966−15.5%Reduced
HighVista Strategies LLC10,951$842.8K0.31%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.11,135$856.0K0.00%+258+2.4%Added
Jump Financial, LLC11,188$861.0K0.02%+11,188New
J. Goldman & Co LP11,634$895.4K0.03%+11,634New
California State Teachers Retirement System12,726$979.4K0.00%+275+2.2%Added
Legal & General Group Plc14,439$1.11M0.00%+610+4.4%Added
Alps Advisors Inc15,066$1.16M0.01%+1,637+12.2%Added
Deutsche Bank AG15,324$1.18M0.00%+5,009+48.6%Added
American Century Companies Inc15,594$1.20M0.00%+5,281+51.2%Added
Simplex Trading, LLC16,854$1.30M0.04%+4,436+35.7%Added
PCG Wealth Advisors, LLC17,282$1.33M0.49%−77−0.4%Reduced
UBS Asset Management Americas Inc18,615$1.43M0.00%+2,747+17.3%Added
Two Sigma Investments, LP20,066$1.54M0.00%−2,700−11.9%Reduced
Rhumbline Advisers22,769$1.75M0.00%−347−1.5%Reduced
Swiss National Bank26,100$2.01M0.00%+1,000+4.0%Added
UBS Oconnor LLC26,503$2.04M0.05%−11,987−31.1%Reduced
Ensign Peak Advisors, Inc27,650$2.13M0.00%+27,650New
Moody Aldrich Partners LLC30,677$2.36M0.44%−928−2.9%Reduced
Qube Research & Technologies Ltd31,999$2.46M0.00%−12,704−28.4%Reduced
Rafferty Asset Management, LLC33,629$2.59M0.01%−1,730−4.9%Reduced
Jane Street Group, LLC37,144$2.86M0.00%−1,401−3.6%Reduced