Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 104
- −4 vs. Q3 2022
- Shares held
- 45.4M
- +3.28M (+7.8%) vs. Q3 2022
- Total value
- $108.1M
- +$12.4M (+13.0%) vs. Q3 2022
- New holders
- 18
- 26 more added
- Sold out
- 22
- 41 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rockefeller Capital Management L.P. | 53 | $0 | 0.00% | −442−89.3% | Reduced |
| Nisa Investment Advisors, LLC | 124 | $0 | 0.00% | +124 | New |
| Credit Suisse AG | 2 | $5 | 0.00% | −15,479−100.0% | Reduced |
| Newbridge Financial Services Group, Inc. | 23 | $55 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 1,222 | $2.00K | 0.00% | −11,620−90.5% | Reduced |
| Cutler Group LP | 1,700 | $4.00K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 2,056 | $4.89K | 0.00% | −7,422−78.3% | Reduced |
| Point72 Middle East FZE | 2,269 | $5.40K | 0.00% | +2,269 | New |
| Ameritas Investment Partners, Inc. | 2,483 | $10.2K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 4,438 | $10.5K | 0.00% | −8,298−65.2% | Reduced |
| FMR LLC | 4,507 | $10.7K | 0.00% | −445,518−99.0% | Reduced |
| Amalgamated Bank | 4,688 | $11.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 4,780 | $11.0K | 0.00% | +4,225+761.3% | Added |
| UBS Group AG | 10,255 | $24.4K | 0.00% | +10,255 | New |
| Zuckerman Investment Group, LLC | 10,479 | $24.9K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 10,539 | $25.1K | 0.00% | +8,935+557.0% | Added |
| Quantum Private Wealth, LLC | 10,640 | $25.3K | 0.02% | −4,477−29.6% | Reduced |
| Invesco Ltd. | 10,640 | $25.3K | 0.00% | −2,253−17.5% | Reduced |
| Prelude Capital Management, LLC | 11,103 | $26.4K | 0.00% | +11,103 | New |
| Cetera Advisors LLC | 11,194 | $26.6K | 0.00% | 00.0% | Unchanged |
| Y-Intercept (Hong Kong) Ltd | 13,865 | $33.0K | 0.00% | −54,642−79.8% | Reduced |
| SG Americas Securities, LLC | 13,739 | $33.0K | 0.00% | −4,078−22.9% | Reduced |
| Deutsche Bank AG | 13,964 | $33.2K | 0.00% | +253+1.8% | Added |
| California State Teachers Retirement System | 15,639 | $37.2K | 0.00% | −30,632−66.2% | Reduced |
| Allspring Global Investments Holdings, LLC | 16,175 | $38.5K | 0.00% | +16,175 | New |
| Mariner, LLC | 17,693 | $42.0K | 0.00% | +4,398+33.1% | Added |
| Cubist Systematic Strategies, LLC | 17,920 | $42.6K | 0.00% | −99,551−84.7% | Reduced |
| Voya Investment Management LLC | 18,069 | $43.0K | 0.00% | +18,069 | New |
| American International Group, Inc. | 18,531 | $44.1K | 0.00% | +570+3.2% | Added |
| Principal Financial Group Inc | 18,800 | $44.7K | 0.00% | +18,800 | New |
| Panagora Asset Management Inc | 18,854 | $44.9K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 20,205 | $48.1K | 0.00% | −14,557−41.9% | Reduced |
| State Board of Administration of Florida Retirement System | 20,871 | $49.7K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 22,880 | $54.0K | 0.00% | −757−3.2% | Reduced |
| Tri Locum Partners LP | 24,147 | $57.0K | 0.03% | +24,147 | New |
| Boothbay Fund Management, LLC | 25,560 | $60.8K | 0.00% | +25,560 | New |
| Squarepoint Ops LLC | 25,618 | $61.0K | 0.00% | −151,588−85.5% | Reduced |
| New York State Common Retirement Fund | 26,332 | $62.7K | 0.00% | −73−0.3% | Reduced |
| Tower Research Capital LLC (TRC) | 26,601 | $63.0K | 0.00% | +9,559+56.1% | Added |
| Atom Investors LP | 26,597 | $63.3K | 0.03% | +26,597 | New |
| Algert Global LLC | 26,830 | $63.9K | 0.00% | +26,830 | New |
| Thrivent Financial for Lutherans | 27,223 | $66.0K | 0.00% | +27,223 | New |
| Alta Wealth Advisors LLC | 31,028 | $73.8K | 0.05% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 42,360 | $101.0K | 0.00% | −21,849−34.0% | Reduced |
| Occudo Quantitative Strategies LP | 43,710 | $104.0K | 0.01% | −62,791−59.0% | Reduced |
| Walleye Capital LLC | 43,745 | $104.1K | 0.00% | +17,006+63.6% | Added |
| Price T Rowe Associates Inc | 47,933 | $114.0K | 0.00% | +12,324+34.6% | Added |
| Public Employees Retirement System of Ohio | 50,286 | $120.0K | 0.00% | −11,414−18.5% | Reduced |
| Ameriprise Financial Inc | 54,698 | $130.0K | 0.00% | +100.0% | Added |
| Rhumbline Advisers | 55,450 | $132.0K | 0.00% | +263+0.5% | Added |
| Jane Street Group, LLC | 57,774 | $137.5K | 0.00% | −45,624−44.1% | Reduced |
| Susquehanna Fundamental Investments, LLC | 62,252 | $148.2K | 0.00% | −10,759−14.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 67,900 | $161.6K | 0.00% | −44,100−39.4% | Reduced |
| Cornercap Investment Counsel Inc | 72,975 | $173.7K | 0.03% | +230+0.3% | Added |
| Tekla Capital Management LLC | 75,000 | $178.5K | 0.01% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 80,700 | $192.1K | 0.00% | +17,100+26.9% | Added |
| Silverarc Capital Management, LLC | 98,409 | $234.2K | 0.08% | −1,591−1.6% | Reduced |
| Point72 Asset Management, L.P. | 100,000 | $238.0K | 0.00% | 00.0% | Unchanged |
| HRT Financial LP | 105,846 | $251.0K | 0.00% | −96,058−47.6% | Reduced |
| Charles Schwab Investment Management Inc | 110,363 | $262.7K | 0.00% | +26,178+31.1% | Added |
| Bridgeway Capital Management, LLC | 113,600 | $270.4K | 0.01% | 00.0% | Unchanged |
| Raymond James & Associates | 115,540 | $275.0K | 0.00% | −2,000−1.7% | Reduced |
| Dimensional Fund Advisors LP | 117,292 | $279.0K | 0.00% | +76,245+185.8% | Added |
| Bank of New York Mellon Corp | 118,790 | $282.7K | 0.00% | 00.0% | Unchanged |
| Los Angeles Capital Management LLC | 132,325 | $314.9K | 0.00% | +26,210+24.7% | Added |
| XTX Topco Ltd | 148,001 | $352.2K | 0.07% | +14,114+10.5% | Added |
| Ikarian Capital, LLC | 150,000 | $357.0K | 0.15% | +150,000 | New |
| AQR Capital Management LLC | 160,529 | $382.1K | 0.00% | −91,223−36.2% | Reduced |
| Millennium Management LLC | 167,067 | $398.0K | 0.00% | −814,871−83.0% | Reduced |
| Morgan Stanley | 182,057 | $433.3K | 0.00% | −92,816−33.8% | Reduced |
| Nuveen Asset Management, LLC | 191,561 | $455.0K | 0.00% | −5,080−2.6% | Reduced |
| Laurion Capital Management LP | 196,669 | $468.1K | 0.01% | −1,429−0.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 252,017 | $599.8K | 0.00% | −15,029−5.6% | Reduced |
| Two Sigma Investments, LP | 278,772 | $663.5K | 0.00% | −163,215−36.9% | Reduced |
| Man Group plc | 306,661 | $729.9K | 0.00% | +67,202+28.1% | Added |
| Northern Trust Corp | 351,871 | $837.5K | 0.00% | −18,723−5.1% | Reduced |
| Renaissance Technologies LLC | 364,000 | $866.0K | 0.00% | −85,116−19.0% | Reduced |
| Federated Hermes, Inc. | 368,430 | $876.9K | 0.00% | +284,953+341.4% | Added |
| CIBC Asset Management Inc | 379,637 | $903.5K | 0.00% | +379,637 | New |
| Two Sigma Advisers, LP | 447,700 | $1.07M | 0.00% | −56,100−11.1% | Reduced |
| D. E. Shaw & Co., Inc. | 574,426 | $1.37M | 0.00% | +290,367+102.2% | Added |
| MPM Oncology Impact Management LP | 610,000 | $1.45M | 0.38% | +610,000 | New |
| Ally Bridge Group (NY) LLC | 630,584 | $1.50M | 1.46% | +630,584 | New |
| Geode Capital Management, LLC | 693,582 | $1.65M | 0.00% | +58,866+9.3% | Added |
| Goldman Sachs Group Inc | 719,452 | $1.71M | 0.00% | −403,151−35.9% | Reduced |
| Citadel Advisors LLC | 755,330 | $1.80M | 0.00% | −325,769−30.1% | Reduced |
| Harvard Management Co Inc | 778,517 | $1.85M | 0.23% | 00.0% | Unchanged |
| Octagon Capital Advisors LP | 800,000 | $1.90M | 0.30% | +800,000 | New |
| State Street Corp | 885,793 | $2.11M | 0.00% | +10,441+1.2% | Added |
| 72 Investment Holdings, LLC | 988,995 | $2.35M | 1.08% | 00.0% | Unchanged |
| Artal Group S.A. | 1,200,000 | $2.86M | 0.16% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 1,353,530 | $3.22M | 0.02% | +331,869+32.5% | Added |
| Vida Ventures Advisors, LLC | 1,469,665 | $3.50M | 4.70% | −1,469,664−50.0% | Reduced |
| Bank of America Corp | 1,514,921 | $3.61M | 0.00% | +1,481,427+4,423.0% | Added |
| EcoR1 Capital, LLC | 1,585,324 | $3.77M | 0.11% | +89,000+5.9% | Added |
| Verition Fund Management LLC | 1,670,371 | $3.98M | 0.08% | +766,063+84.7% | Added |
| Vanguard Group Inc | 1,786,296 | $4.25M | 0.00% | −18,057−1.0% | Reduced |
| Baker Bros. Advisors LP | 1,830,315 | $4.36M | 0.03% | +1,830,315 | New |
| Adage Capital Partners GP, L.L.C. | 2,256,041 | $5.37M | 0.01% | 00.0% | Unchanged |
| PFM Health Sciences, LP | 2,777,467 | $6.61M | 0.28% | −681,058−19.7% | Reduced |