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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Praxis Precision Medicines, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
309
+20 vs. Q1 2026
Shares held
33.7M
+5.40M (+19.0%) vs. Q1 2026
Total value
$11.3B
+$2.17B (+23.8%) vs. Q1 2026
New holders
59
123 more added
Sold out
39
93 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 309 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ2 2026: $11.3B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q1 2026.

Institutions holding PRAX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Mercer Global Advisors Inc1,699$568.8K0.00%−151−8.2%Reduced
E Fund Management Co., Ltd.1,684$563.8K0.01%−272−13.9%Reduced
Group One Trading, L.P.1,666$557.8K0.02%+1,537+1,191.5%Added
The PNC Financial Services Group, Inc.1,593$533.3K0.00%+640+67.2%Added
University of Texas/Texas Am Investment Managment Co1,525$510.6K0.06%+1,525New
Swiss Life Asset Management Ltd1,522$509.6K0.00%+120+8.6%Added
StoneX Group Inc.1,521$508.0K0.02%+52+3.5%Added
Brevan Howard Capital Management LP1,478$494.8K0.01%+506+52.1%Added
CIBC Bancorp USA Inc.1,397$467.7K0.00%+85+6.5%Added
Los Angeles Capital Management LLC1,364$456.7K0.00%−3,696−73.0%Reduced
Dark Forest Capital Management LP1,331$445.6K0.03%+1,331New
Himension Fund1,327$444.3K0.03%+1,327New
Mitsubishi UFJ Trust & Banking Corp1,317$440.9K0.00%+1,317New
Englebert Financial Advisers, LLC1,306$437.2K0.43%+517+65.5%Added
US Bancorp1,260$421.8K0.00%−279−18.1%Reduced
Mirae Asset Global Investments Co., Ltd.1,247$417.5K0.00%−206−14.2%Reduced
Virtus Investment Advisers, Inc.1,227$410.8K0.10%+214+21.1%Added
XTX Topco Ltd1,175$393.4K0.01%−169−12.6%Reduced
JustInvest LLC1,170$391.7K0.00%−174−12.9%Reduced
Cerity Partners LLC1,159$388.0K0.00%−440−27.5%Reduced
Daiwa Securities Group Inc.1,151$385.3K0.00%+205+21.7%Added
DnB Asset Management AS1,146$383.7K0.00%00.0%Unchanged
Brinker Capital Investments, LLC1,081$361.9K0.00%−653−37.7%Reduced
Jupiter Asset Management Ltd1,052$352.2K0.00%+1,052New
Abel Hall, LLC1,019$341.2K0.06%−373−26.8%Reduced
Jane Street Group, LLC1,008$337.5K0.00%+1,008New
Atria Investments LLC1,001$335.1K0.00%−59−5.6%Reduced
Millennium Management LLC995$333.1K0.00%−2,836−74.0%Reduced
HSBC Holdings PLC942$325.0K0.00%−692−42.4%Reduced
M&T Bank Corp966$323.1K0.00%+31+3.3%Added
Gallagher Fiduciary Advisors, LLC957$320.4K0.01%−33−3.3%Reduced
Eagle Bay Advisors LLC956$320.1K0.24%+956New
Brick & Kyle, Associates966$311.2K0.10%00.0%Unchanged
O'Shaughnessy Asset Management, LLC891$298.3K0.00%+52+6.2%Added
Virtus ETF Advisers LLC883$295.6K0.11%+883New
Inscription Capital, LLC866$289.9K0.03%00.0%Unchanged
CIBC Asset Management Inc862$288.6K0.00%−38−4.2%Reduced
Everence Capital Management Inc832$279.0K0.01%+832New
Ieq Capital, LLC815$272.9K0.00%−27−3.2%Reduced
VARCOV Co.815$272.9K0.10%+815New
Bank of Montreal797$266.8K0.00%−7−0.9%Reduced
Two Sigma Securities, LLC793$265.5K0.02%+793New
Nykredit A/S779$260.8K0.00%+779New
Chicago Partners Investment Group LLC781$251.8K0.01%−52−6.2%Reduced
Acadian Asset Management LLC741$246.0K0.00%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC745$242.1K0.00%−42−5.3%Reduced
KBC Group NV715$239.0K0.00%00.0%Unchanged
Amalgamated Bank682$228.0K0.00%−26−3.7%Reduced
NBC Securities, Inc.668$223.6K0.02%00.0%Unchanged
Mariner, LLC650$217.6K0.00%−527−44.8%Reduced
GF Fund Management Co. Ltd.592$198.2K0.00%+30+5.3%Added
Global Retirement Partners, LLC403$134.9K0.00%+403New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.360$120.5K0.00%−64−15.1%Reduced
GAMMA Investing LLC332$111.2K0.00%+31+10.3%Added
Eurizon Capital SGR S.p.A.306$107.4K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.315$105.5K0.00%00.0%Unchanged
Kemnay Advisory Services Inc.248$83.0K0.01%+27+12.2%Added
Farther Finance Advisors, LLC237$79.4K0.00%−1−0.4%Reduced
Pacer Advisors, Inc.192$64.0K0.00%+192New
Bernard Wealth Management Corp.181$60.6K0.02%+181New
SRS Capital Advisors, Inc.168$56.2K0.00%+130+342.1%Added
Bessemer Group Inc140$47.0K0.00%+140New
Optiver Holding B.V.131$43.9K0.00%+94+254.1%Added
Advisor Group Holdings, Inc.124$41.5K0.00%+30+31.9%Added
Smartleaf Asset Management LLC99$34.7K0.00%00.0%Unchanged
Toronto Dominion Bank90$30.1K0.00%−199−68.9%Reduced
Sterling Capital Management LLC88$29.5K0.00%−716−89.1%Reduced
Pinnacle Wealth Planning Services, Inc.87$29.1K0.00%+6+7.4%Added
Allworth Financial LP78$26.1K0.00%+3+4.0%Added
Larson Financial Group LLC68$22.8K0.00%−30−30.6%Reduced
E Fund Management (Hong Kong) Co., Ltd.66$22.1K0.01%+20+43.5%Added
J.Safra Asset Management Corp61$20.4K0.00%+7+13.0%Added
Bayforest Capital Ltd58$19.4K0.02%+58New
Rothschild Investment LLC56$18.7K0.00%−13−18.8%Reduced
SBI Securities Co., Ltd.55$18.4K0.00%−12−17.9%Reduced
First Horizon Corp53$17.7K0.00%+5+10.4%Added
Accent Capital Management, LLC50$16.7K0.01%00.0%Unchanged
Federated Hermes, Inc.44$14.7K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC32$10.7K0.00%+8+33.3%Added
EverSource Wealth Advisors, LLC30$10.0K0.00%−20−40.0%Reduced
Jones Financial Companies LLLP29$9.51K0.00%−2−6.5%Reduced
Steward Partners Investment Advisory, LLC28$9.37K0.00%+18+180.0%Added
IFP Advisors, Inc25$8.37K0.00%+19+316.7%Added
Covestor Ltd23$8.00K0.00%−1−4.2%Reduced
Signaturefd, LLC21$7.03K0.00%−9−30.0%Reduced
Essential Partners LLC21$7.03K0.00%+17+425.0%Added
Parkside Financial Bank & Trust14$4.69K0.00%00.0%Unchanged
Ares Financial Consulting, LLC13$4.35K0.00%+13New
Northwestern Mutual Wealth Management Co12$4.02K0.00%+12New
Keating Financial Advisory Services, Inc.10$3.35K0.00%+2+25.0%Added
Meeder Asset Management Inc7$2.34K0.00%−9−56.3%Reduced
Bare Financial Services, Inc6$2.01K0.00%−4−40.0%Reduced
Bell Investment Advisors, Inc5$1.67K0.00%00.0%Unchanged
UMA Financial Services, Inc.5$1.67K0.00%+1+25.0%Added
Rakuten Securities, Inc.3$1.00K0.00%−22−88.0%Reduced
Zions Bancorporation, National Association3$1.00K0.00%+1+50.0%Added
Hughes Financial Services, LLC3$1.00K0.00%+2+200.0%Added
Action Point Financial Planning, LLC3$1.00K0.00%+3New
Avion Wealth3$1.00K0.00%+3New
Massmutual Trust Co FSB2$6700.00%−5−71.4%Reduced