Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 152
- +9 vs. Q2 2025
- Shares held
- 24.7M
- +519.5K (+2.2%) vs. Q2 2025
- Total value
- $1.31B
- +$291.9M (+28.8%) vs. Q2 2025
- New holders
- 27
- 60 more added
- Sold out
- 18
- 45 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 2 | $0 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 1 | $53 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 2 | $106 | 0.00% | +2 | New |
| IFP Advisors, Inc | 3 | $159 | 0.00% | +3 | Added |
| Parkside Financial Bank & Trust | 10 | $530 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 12 | $636 | 0.00% | −57−82.6% | Reduced |
| EverSource Wealth Advisors, LLC | 18 | $954 | 0.00% | 00.0% | Unchanged |
| Hemington Wealth Management | 30 | $1.00K | 0.00% | 00.0% | Unchanged |
| FSA Wealth Management LLC | 21 | $1.11K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 24 | $1.27K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 45 | $2.38K | 0.00% | −5−10.0% | Reduced |
| Daiwa Securities Group Inc. | 62 | $3.00K | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 71 | $3.76K | 0.00% | +33+86.8% | Added |
| Advisor Group Holdings, Inc. | 80 | $4.16K | 0.00% | +26+48.1% | Added |
| SBI Securities Co., Ltd. | 83 | $4.40K | 0.00% | +8+10.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 98 | $5.19K | 0.00% | −69−41.3% | Reduced |
| US Bancorp | 112 | $5.94K | 0.00% | −54−32.5% | Reduced |
| Optiver Holding B.V. | 140 | $7.42K | 0.00% | +140 | New |
| GAMMA Investing LLC | 150 | $7.95K | 0.00% | −5−3.2% | Reduced |
| SRS Capital Advisors, Inc. | 152 | $8.06K | 0.00% | +129+560.9% | Added |
| Clear Street Markets LLC | 164 | $8.69K | 0.00% | +164 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 163 | $9.00K | 0.00% | +30+22.6% | Added |
| Public Employees Retirement Association of Colorado | 217 | $12.0K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 230 | $12.2K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 453 | $24.0K | 0.00% | −24−5.0% | Reduced |
| Amalgamated Bank | 599 | $32.0K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 757 | $40.0K | 0.00% | +4+0.5% | Added |
| Mirae Asset Global Investments Co., Ltd. | 814 | $43.1K | 0.00% | +27+3.4% | Added |
| Sterling Capital Management LLC | 1,146 | $60.7K | 0.00% | +701+157.5% | Added |
| Ameritas Investment Partners, Inc. | 1,519 | $80.5K | 0.00% | −170−10.1% | Reduced |
| Quest Partners LLC | 1,999 | $105.9K | 0.01% | +1,883+1,623.3% | Added |
| Jefferies Financial Group Inc. | 2,000 | $106.0K | 0.00% | −3,000−60.0% | Reduced |
| Tower Research Capital LLC (TRC) | 2,127 | $112.7K | 0.00% | +290+15.8% | Added |
| Virtus Investment Advisers, Inc. | 2,527 | $133.9K | 0.04% | +439+21.0% | Added |
| Citigroup Inc | 2,807 | $148.8K | 0.00% | −9,059−76.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 3,689 | $195.5K | 0.02% | −402−9.8% | Reduced |
| ProShare Advisors LLC | 3,826 | $202.8K | 0.00% | +3,826 | New |
| Coastal Bridge Advisors, LLC | 3,846 | $203.8K | 0.02% | +3,846 | New |
| Virginia Retirement Systems Et Al | 3,900 | $206.7K | 0.00% | +3,900 | New |
| Royal Bank of Canada | 3,956 | $209.0K | 0.00% | −18,637−82.5% | Reduced |
| KLP Kapitalforvaltning AS | 4,000 | $212.0K | 0.00% | +1,200+42.9% | Added |
| BNP Paribas Arbitrage, SA | 4,385 | $232.4K | 0.00% | +2,338+114.2% | Added |
| Russell Investments Group, Ltd. | 4,404 | $233.4K | 0.00% | +4,155+1,668.7% | Added |
| Teacher Retirement System of Texas | 4,469 | $236.9K | 0.00% | +4,469 | New |
| Police & Firemen's Retirement System of New Jersey | 4,915 | $260.5K | 0.00% | +1,126+29.7% | Added |
| Arizona State Retirement System | 5,417 | $287.1K | 0.00% | +5,417 | New |
| Cerity Partners LLC | 5,450 | $288.9K | 0.00% | −161−2.9% | Reduced |
| Two Sigma Investments, LP | 5,508 | $291.9K | 0.00% | −1,001−15.4% | Reduced |
| Lion Point Capital, LP | 5,700 | $302.1K | 1.72% | +5,700 | New |
| Gsa Capital Partners LLP | 5,740 | $304.0K | 0.03% | −6,268−52.2% | Reduced |
| Caption Management, LLC | 6,357 | $336.9K | 0.02% | −32,679−83.7% | Reduced |
| State Board of Administration of Florida Retirement System | 6,425 | $340.5K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 6,600 | $349.8K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 6,660 | $353.0K | 0.00% | +165+2.5% | Added |
| Phoenix Holdings Ltd. | 6,817 | $361.5K | 0.00% | +6,817 | New |
| Nisa Investment Advisors, LLC | 7,129 | $377.8K | 0.00% | +6,500+1,033.4% | Added |
| Intech Investment Management LLC | 7,754 | $411.0K | 0.00% | −965−11.1% | Reduced |
| Citadel Advisors LLC | 7,798 | $413.3K | 0.00% | −2,568−24.8% | Reduced |
| Profund Advisors LLC | 8,079 | $428.2K | 0.01% | +2,818+53.6% | Added |
| Freestone Grove Partners LP | 8,269 | $438.3K | 0.00% | +8,269 | New |
| Trexquant Investment LP | 8,905 | $472.0K | 0.00% | +8,905 | New |
| State of Wisconsin Investment Board | 9,033 | $478.7K | 0.00% | −5,726−38.8% | Reduced |
| Alps Advisors Inc | 10,424 | $552.5K | 0.00% | −570−5.2% | Reduced |
| Hussman Strategic Advisors, Inc. | 10,500 | $556.5K | 0.12% | 00.0% | Unchanged |
| MetLife Investment Management | 10,520 | $557.6K | 0.00% | 00.0% | Unchanged |
| HSBC Holdings PLC | 11,172 | $594.7K | 0.00% | +11,172 | New |
| SG Americas Securities, LLC | 13,496 | $715.0K | 0.00% | +13,496 | New |
| Wells Fargo & Company | 13,605 | $721.1K | 0.00% | +2,353+20.9% | Added |
| Deutsche Bank AG | 13,856 | $734.4K | 0.00% | +1,732+14.3% | Added |
| Jacobs Levy Equity Management, Inc | 13,898 | $736.6K | 0.00% | −31,184−69.2% | Reduced |
| PCG Wealth Advisors, LLC | 14,483 | $767.6K | 0.22% | +14,483 | New |
| American Century Companies Inc | 15,268 | $809.2K | 0.00% | +15,268 | New |
| Group One Trading, L.P. | 16,628 | $881.3K | 0.03% | +16,628 | New |
| Legal & General Group Plc | 16,824 | $891.7K | 0.00% | +154+0.9% | Added |
| Alliancebernstein L.P. | 18,060 | $957.2K | 0.00% | +20+0.1% | Added |
| California State Teachers Retirement System | 18,583 | $984.9K | 0.00% | +2,237+13.7% | Added |
| D. E. Shaw & Co., Inc. | 19,796 | $1.05M | 0.00% | +740+3.9% | Added |
| Quarry LP | 20,001 | $1.06M | 0.26% | +15,201+316.7% | Added |
| Invesco Ltd. | 20,868 | $1.11M | 0.00% | +4,929+30.9% | Added |
| Dark Forest Capital Management LP | 21,684 | $1.15M | 0.04% | +21,684 | New |
| AQR Capital Management LLC | 21,904 | $1.16M | 0.00% | +7,324+50.2% | Added |
| Simplex Trading, LLC | 22,529 | $1.19M | 0.03% | −2,799−11.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 22,836 | $1.21M | 0.00% | −1,037−4.3% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 23,251 | $1.23M | 0.02% | +17,501+304.4% | Added |
| UBS Asset Management Americas Inc | 23,756 | $1.26M | 0.00% | −73,189−75.5% | Reduced |
| JPMorgan Chase & Co | 26,208 | $1.39M | 0.00% | +12,270+88.0% | Added |
| Rhumbline Advisers | 26,794 | $1.42M | 0.00% | −547−2.0% | Reduced |
| Knott David M Jr | 28,000 | $1.48M | 0.62% | +28,000 | New |
| Prelude Capital Management, LLC | 28,102 | $1.49M | 0.12% | +8,202+41.2% | Added |
| Ikarian Capital, LLC | 28,571 | $1.51M | 0.34% | −248,379−89.7% | Reduced |
| First Trust Advisors LP | 28,966 | $1.54M | 0.00% | +28,966 | New |
| Susquehanna International Group, LLP | 29,337 | $1.55M | 0.00% | −17,590−37.5% | Reduced |
| Congress Asset Management Co | 30,439 | $1.61M | 0.01% | +30,439 | New |
| B Group, Inc. | 31,500 | $1.67M | 1.60% | −3,500−10.0% | Reduced |
| Jane Street Group, LLC | 31,687 | $1.68M | 0.00% | +18,684+143.7% | Added |
| Y-Intercept (Hong Kong) Ltd | 32,186 | $1.71M | 0.04% | +32,186 | New |
| SummitTX Capital, L.P. | 34,928 | $1.85M | 0.08% | +34,928 | New |
| Swiss National Bank | 35,500 | $1.88M | 0.00% | +4,700+15.3% | Added |
| Manufacturers Life Insurance Company, The | 35,829 | $1.90M | 0.00% | −20,302−36.2% | Reduced |
| Dimensional Fund Advisors LP | 37,414 | $1.98M | 0.00% | +37,414 | New |