Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 291
- +48 vs. Q4 2025
- Shares held
- 31.8M
- +3.79M (+13.5%) vs. Q4 2025
- Total value
- $10.2B
- +$1.98B (+24.0%) vs. Q4 2025
- New holders
- 80
- 121 more added
- Sold out
- 32
- 68 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Boothbay Fund Management, LLC | 17,587 | $5.67M | 0.13% | −3,387−16.1% | Reduced |
| Creative Planning | 16,286 | $5.25M | 0.00% | +5,443+50.2% | Added |
| Algert Global LLC | 16,168 | $5.21M | 0.08% | −64,472−80.0% | Reduced |
| Polygon Management Ltd. | 15,952 | $5.14M | 1.01% | −7,000−30.5% | Reduced |
| J. Goldman & Co LP | 15,664 | $5.05M | 0.23% | +10,114+182.2% | Added |
| Rafferty Asset Management, LLC | 15,188 | $4.89M | 0.02% | −7,052−31.7% | Reduced |
| ExodusPoint Capital Management, LP | 14,742 | $4.75M | 0.05% | +14,742 | New |
| State of Wisconsin Investment Board | 14,642 | $4.72M | 0.01% | −589−3.9% | Reduced |
| Victory Capital Management Inc | 14,132 | $4.55M | 0.00% | +834+6.3% | Added |
| Allianz Asset Management GmbH | 14,030 | $4.52M | 0.01% | +11,630+484.6% | Added |
| Mutual of America Capital Management LLC | 12,473 | $4.02M | 0.05% | +12,473 | New |
| Wells Fargo & Company | 11,614 | $3.74M | 0.00% | −13,621−54.0% | Reduced |
| Vanguard Global Advisers, LLC | 11,335 | $3.65M | 0.00% | +11,335 | New |
| Polen Capital Management LLC | 10,043 | $3.24M | 0.02% | +10,043 | New |
| Braidwell LP | 9,976 | $3.21M | 0.11% | +9,976 | New |
| Prelude Capital Management, LLC | 9,064 | $2.92M | 0.22% | −6,974−43.5% | Reduced |
| Erste Asset Management GmbH | 10,500 | $2.90M | 0.03% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 8,749 | $2.82M | 0.00% | +1,449+19.8% | Added |
| Susquehanna International Group, LLP | 8,517 | $2.74M | 0.00% | +6,174+263.5% | Added |
| Allspring Global Investments Holdings, LLC | 8,536 | $2.73M | 0.00% | +6,804+392.8% | Added |
| State of New Jersey Common Pension Fund D | 8,058 | $2.60M | 0.01% | +1,040+14.8% | Added |
| Massachusetts Financial Services Co | 7,388 | $2.38M | 0.00% | +4,072+122.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 7,194 | $2.32M | 0.01% | +324+4.7% | Added |
| Profund Advisors LLC | 7,081 | $2.28M | 0.08% | −1,374−16.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 6,989 | $2.25M | 0.02% | +932+15.4% | Added |
| Barclays PLC | 6,979 | $2.25M | 0.00% | −523,772−98.7% | Reduced |
| Intech Investment Management LLC | 6,977 | $2.25M | 0.02% | −1,757−20.1% | Reduced |
| Vestmark Advisory Solutions, Inc. | 6,681 | $2.15M | 0.02% | +2,176+48.3% | Added |
| Trexquant Investment LP | 6,626 | $2.13M | 0.02% | −1,705−20.5% | Reduced |
| Arizona State Retirement System | 6,476 | $2.09M | 0.01% | +753+13.2% | Added |
| Nisa Investment Advisors, LLC | 6,280 | $2.02M | 0.01% | −1,490−19.2% | Reduced |
| Vanguard Investments Australia, Ltd. | 5,936 | $1.91M | 0.01% | +5,936 | New |
| State Board of Administration of Florida Retirement System | 5,902 | $1.90M | 0.00% | +96+1.7% | Added |
| Citigroup Inc | 5,646 | $1.82M | 0.00% | +60+1.1% | Added |
| Raymond James Financial Inc | 5,320 | $1.71M | 0.00% | +85+1.6% | Added |
| KLP Kapitalforvaltning AS | 5,200 | $1.68M | 0.01% | +800+18.2% | Added |
| Los Angeles Capital Management LLC | 5,060 | $1.63M | 0.01% | +4,508+816.7% | Added |
| Ghisallo Capital Management LLC | 5,000 | $1.61M | 0.04% | +5,000 | New |
| ProShare Advisors LLC | 4,988 | $1.61M | 0.00% | −226−4.3% | Reduced |
| China Universal Asset Management Co., Ltd. | 4,942 | $1.59M | 0.12% | +67+1.4% | Added |
| Envestnet Asset Management Inc | 4,862 | $1.57M | 0.00% | −688−12.4% | Reduced |
| Lion Point Capital, LP | 4,450 | $1.43M | 8.57% | 00.0% | Unchanged |
| Hussman Strategic Advisors, Inc. | 4,200 | $1.35M | 0.29% | −4,200−50.0% | Reduced |
| Royal Bank of Canada | 4,133 | $1.33M | 0.00% | +755+22.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 4,049 | $1.30M | 0.00% | +3,951+4,031.6% | Added |
| Nicholas Investment Partners, LP | 3,948 | $1.27M | 0.09% | +3,948 | New |
| Coastal Bridge Advisors, LLC | 3,906 | $1.26M | 0.09% | −248−6.0% | Reduced |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 3,855 | $1.24M | 1.81% | +1,773+85.2% | Added |
| Millennium Management LLC | 3,831 | $1.23M | 0.00% | +3,831 | New |
| STRS Ohio | 3,600 | $1.16M | 0.00% | +400+12.5% | Added |
| Fifth Third Bancorp | 3,589 | $1.16M | 0.00% | +3,589 | New |
| Allstate Corp | 3,512 | $1.13M | 0.01% | +3,512 | New |
| Glenmede Trust Co NA | 3,410 | $1.10M | 0.01% | −2,878−45.8% | Reduced |
| FORA Capital, LLC | 3,412 | $1.10M | 0.08% | +3,412 | New |
| Quantinno Capital Management LP | 3,320 | $1.07M | 0.00% | +597+21.9% | Added |
| RE Advisers Corp | 3,300 | $1.06M | 0.03% | +3,300 | New |
| Man Group plc | 3,173 | $1.02M | 0.00% | −17,997−85.0% | Reduced |
| Teacher Retirement System of Texas | 3,062 | $986.5K | 0.00% | +9+0.3% | Added |
| LPL Financial LLC | 2,923 | $941.8K | 0.00% | +2,923 | New |
| Quarry LP | 2,750 | $886.0K | 0.18% | −1,250−31.3% | Reduced |
| ACT Capital Management, LLC | 2,700 | $869.9K | 0.68% | +2,000+285.7% | Added |
| Guggenheim Capital LLC | 2,670 | $860.2K | 0.01% | +2,670 | New |
| Artia Global Partners LP | 2,500 | $805.5K | 0.18% | 00.0% | Unchanged |
| Xponance, Inc. | 2,420 | $779.7K | 0.01% | +656+37.2% | Added |
| Public Employees Retirement Association of Colorado | 2,390 | $770.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,113 | $680.8K | 0.02% | +247+13.2% | Added |
| Squarepoint Ops LLC | 2,010 | $647.6K | 0.00% | +120+6.3% | Added |
| Ethic Inc. | 1,990 | $641.2K | 0.01% | −203−9.3% | Reduced |
| E Fund Management Co., Ltd. | 1,956 | $630.2K | 0.02% | +1,956 | New |
| Mercer Global Advisors Inc | 1,850 | $596.1K | 0.00% | +638+52.6% | Added |
| Amundi | 1,802 | $580.6K | 0.00% | +1,012+128.1% | Added |
| Virginia Retirement Systems Et Al | 1,800 | $579.9K | 0.00% | −1,700−48.6% | Reduced |
| Bellevue Group AG | 1,757 | $566.1K | 0.01% | +1,757 | New |
| Brinker Capital Investments, LLC | 1,734 | $558.7K | 0.00% | −251−12.6% | Reduced |
| Simplex Trading, LLC | 1,660 | $534.8K | 0.02% | +1,660 | New |
| Hudson Bay Capital Management LP | 1,640 | $528.4K | 0.00% | +1,640 | New |
| Martingale Asset Management L P | 1,615 | $520.3K | 0.01% | +559+52.9% | Added |
| HSBC Holdings PLC | 1,634 | $518.3K | 0.00% | +809+98.1% | Added |
| Cerity Partners LLC | 1,599 | $515.2K | 0.00% | −2,328−59.3% | Reduced |
| US Bancorp | 1,539 | $495.9K | 0.00% | −286−15.7% | Reduced |
| Centiva Capital, LP | 1,501 | $483.6K | 0.02% | +1,501 | New |
| PSP Research LLC | 1,500 | $483.3K | 0.34% | −482−24.3% | Reduced |
| ADAR1 Capital Management, LLC | 1,500 | $483.3K | 0.03% | 00.0% | Unchanged |
| StoneX Group Inc. | 1,469 | $473.3K | 0.03% | −297−16.8% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,453 | $468.1K | 0.00% | +238+19.6% | Added |
| CWM, LLC | 1,432 | $461.4K | 0.00% | +558+63.8% | Added |
| Swiss Life Asset Management Ltd | 1,402 | $451.7K | 0.00% | +456+48.2% | Added |
| Abel Hall, LLC | 1,392 | $448.5K | 0.10% | +360+34.9% | Added |
| JustInvest LLC | 1,344 | $433.0K | 0.00% | +1,344 | New |
| XTX Topco Ltd | 1,344 | $433.0K | 0.01% | +1,344 | New |
| Tower Research Capital LLC (TRC) | 1,333 | $429.5K | 0.01% | +722+118.2% | Added |
| CIBC Bancorp USA Inc. | 1,312 | $422.7K | 0.00% | +1,312 | New |
| Integrated Quantitative Investments LLC | 1,253 | $403.7K | 0.07% | +1,253 | New |
| Fieldview Capital Management, LLC | 1,223 | $394.0K | 0.12% | +1,223 | New |
| Fox Run Management, L.L.C. | 1,393 | $385.1K | 0.07% | +1,393 | New |
| Mariner, LLC | 1,177 | $378.8K | 0.00% | +1,177 | New |
| Principal Financial Group Inc | 1,153 | $371.5K | 0.00% | +158+15.9% | Added |
| DnB Asset Management AS | 1,146 | $369.2K | 0.00% | +1,146 | New |
| AlphaGrep UK Ltd | 1,134 | $365.4K | 0.11% | +1,134 | New |
| Persistent Asset Partners Ltd | 1,131 | $364.4K | 0.14% | −276−19.6% | Reduced |