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Praxis Precision Medicines, Inc.

PRAX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001689548

No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
291
+48 vs. Q4 2025
Shares held
31.8M
+3.79M (+13.5%) vs. Q4 2025
Total value
$10.2B
+$1.98B (+24.0%) vs. Q4 2025
New holders
80
121 more added
Sold out
32
68 more reduced

7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 291 institutions
Q1 2021: 68 institutionsQ2 2021: 80 institutionsQ3 2021: 93 institutionsQ4 2021: 100 institutionsQ1 2022: 103 institutionsQ2 2022: 95 institutionsQ3 2022: 108 institutionsQ4 2022: 104 institutionsQ1 2023: 87 institutionsQ2 2023: 78 institutionsQ3 2023: 74 institutionsQ4 2023: 60 institutionsQ1 2024: 111 institutionsQ2 2024: 113 institutionsQ3 2024: 134 institutionsQ4 2024: 162 institutionsQ1 2025: 150 institutionsQ2 2025: 144 institutionsQ3 2025: 152 institutionsQ4 2025: 250 institutionsQ1 2026: 291 institutionsQ2 2026: 309 institutions
Value heldQ1 2026: $10.2B
Q1 2021: $1.19BQ2 2021: $751.0MQ3 2021: $791.5MQ4 2021: $863.1MQ1 2022: $463.4MQ2 2022: $105.5MQ3 2022: $95.7MQ4 2022: $108.1MQ1 2023: $43.1MQ2 2023: $134.6MQ3 2023: $195.6MQ4 2023: $178.6MQ1 2024: $971.3MQ2 2024: $762.1MQ3 2024: $1.09BQ4 2024: $1.67BQ1 2025: $889.3MQ2 2025: $1.02BQ3 2025: $1.31BQ4 2025: $8.69BQ1 2026: $10.2BQ2 2026: $11.3B
Institutions holding PRAX and their total value by quarter
QuarterHoldersValue
Q2 2026309$11.3B
Q1 2026291$10.2B
Q4 2025250$8.69B
Q3 2025152$1.31B
Q2 2025144$1.02B
Q1 2025150$889.3M
Q4 2024162$1.67B
Q3 2024134$1.09B
Q2 2024113$762.1M
Q1 2024111$971.3M
Q4 202360$178.6M
Q3 202374$195.6M
Q2 202378$134.6M
Q1 202387$43.1M
Q4 2022104$108.1M
Q3 2022108$95.7M
Q2 202295$105.5M
Q1 2022103$463.4M
Q4 2021100$863.1M
Q3 202193$791.5M
Q2 202180$751.0M
Q1 202168$1.19B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.

Institutions holding PRAX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Atria Investments LLC1,060$341.5K0.00%+1,060New
Virtus Investment Advisers, Inc.1,013$326.4K0.09%+24+2.4%Added
QP Wealth Management, LLC995$320.6K0.55%+995New
Gallagher Fiduciary Advisors, LLC990$319.0K0.01%+990New
Carl P. Sherr & Co., LLC972$313.2K0.15%+75+8.4%Added
Brevan Howard Capital Management LP972$313.2K0.00%+972New
Brick & Kyle, Associates966$311.2K0.10%+966New
The PNC Financial Services Group, Inc.953$307.0K0.00%+239+33.5%Added
Daiwa Securities Group Inc.946$304.8K0.00%+874+1,213.9%Added
M&T Bank Corp935$301.3K0.00%+50+5.6%Added
CTC Alternative Strategies, Ltd.925$298.0K0.68%+925New
CIBC Asset Management Inc900$290.0K0.00%00.0%Unchanged
Chicago Partners Investment Group LLC833$281.0K0.01%+833New
Inscription Capital, LLC866$279.0K0.03%00.0%Unchanged
SG Americas Securities, LLC852$275.0K0.00%−9,113−91.5%Reduced
Ieq Capital, LLC842$271.3K0.00%+27+3.3%Added
O'Shaughnessy Asset Management, LLC839$270.3K0.00%+71+9.2%Added
GTS Securities LLC837$269.7K0.01%+837New
Sterling Capital Management LLC804$259.0K0.00%−407−33.6%Reduced
Bank of Montreal804$259.0K0.00%+804New
Perbak Capital Partners LLP799$257.4K0.06%+799New
Englebert Financial Advisers, LLC789$254.2K0.29%+789New
Wealth Enhancement Advisory Services, LLC787$244.3K0.00%+787New
Pinnacle Associates Ltd744$239.7K0.00%+744New
Pinnacle Wealth Management Advisory Group, LLC744$239.7K0.02%+744New
Acadian Asset Management LLC741$238.0K0.00%+112+17.8%Added
KBC Group NV715$230.0K0.00%+39+5.8%Added
Amalgamated Bank708$228.0K0.00%00.0%Unchanged
Legato Capital Management LLC670$215.9K0.02%+670New
Scientech Research LLC669$215.5K0.18%+669New
NBC Securities, Inc.668$215.2K0.02%+538+413.8%Added
Westfield Capital Management Co LP662$213.3K0.00%+662New
Commonwealth Equity Services, LLC660$212.7K0.00%−85−11.4%Reduced
MML Investors Services, LLC639$205.9K0.00%−225−26.0%Reduced
GF Fund Management Co. Ltd.562$181.1K0.00%+72+14.7%Added
Caitong International Asset Management Co., Ltd472$152.1K0.03%+472New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.424$136.6K0.00%+145+52.0%Added
ABS Direct Equity Fund LLC400$135.0K0.10%+400New
Rockefeller Capital Management L.P.315$101.5K0.00%+251+392.2%Added
GAMMA Investing LLC301$97.0K0.00%+63+26.5%Added
Toronto Dominion Bank289$93.1K0.00%+289New
Eurizon Capital SGR S.p.A.306$85.0K0.00%+306New
Farther Finance Advisors, LLC238$76.0K0.00%−130−35.3%Reduced
Kemnay Advisory Services Inc.221$71.2K0.01%+160+262.3%Added
Group One Trading, L.P.129$41.6K0.00%−5,410−97.7%Reduced
Parallel Advisors, LLC124$40.0K0.00%+120+3,000.0%Added
MAI Capital Management106$34.2K0.00%+102+2,550.0%Added
Larson Financial Group LLC98$31.6K0.00%+8+8.9%Added
Advisor Group Holdings, Inc.94$30.3K0.00%+11+13.3%Added
Smartleaf Asset Management LLC99$27.4K0.00%+25+33.8%Added
Pinnacle Wealth Planning Services, Inc.81$26.1K0.00%+81New
Allworth Financial LP75$24.2K0.00%+47+167.9%Added
Rothschild Investment LLC69$22.2K0.00%+19+38.0%Added
SBI Securities Co., Ltd.67$21.6K0.00%−7−9.5%Reduced
J.Safra Asset Management Corp54$17.4K0.00%+36+200.0%Added
Accent Capital Management, LLC50$16.1K0.01%00.0%Unchanged
EverSource Wealth Advisors, LLC50$16.1K0.00%+25+100.0%Added
First Horizon Corp48$15.5K0.00%+48New
E Fund Management (Hong Kong) Co., Ltd.46$14.8K0.01%+46New
Federated Hermes, Inc.44$14.2K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.38$12.2K0.00%−26−40.6%Reduced
Optiver Holding B.V.37$11.9K0.00%−23−38.3%Reduced
Aster Capital Management (DIFC) Ltd260$9.85K0.00%+260New
Signaturefd, LLC30$9.67K0.00%+30New
Jones Financial Companies LLLP31$8.99K0.00%+31New
Rakuten Securities, Inc.25$8.05K0.00%+25New
Covestor Ltd24$8.00K0.01%+22+1,100.0%Added
Basecamp Wealth Advisors LLC24$7.73K0.00%+8+50.0%Added
Golden State Equity Partners24$7.73K0.00%+24New
AdvisorNet Financial, Inc20$6.44K0.00%+20New
Meeder Asset Management Inc16$5.16K0.00%+16New
Parkside Financial Bank & Trust14$4.51K0.00%00.0%Unchanged
Bare Financial Services, Inc10$3.22K0.00%+1+11.1%Added
Steward Partners Investment Advisory, LLC10$3.22K0.00%+10New
Keating Financial Advisory Services, Inc.8$2.58K0.00%+7+700.0%Added
Massmutual Trust Co FSB7$2.25K0.00%+7New
Fortitude Family Office, LLC7$2.25K0.00%+7New
Root Financial Partners, LLC7$2.25K0.00%+7New
IFP Advisors, Inc6$1.93K0.00%00.0%Unchanged
Bell Investment Advisors, Inc5$1.61K0.00%00.0%Unchanged
Wealth Preservation Advisors, LLC5$1.61K0.00%+5New
Twin Peaks Wealth Advisors, LLC5$1.61K0.00%+5New
Essential Partners LLC4$1.29K0.00%00.0%Unchanged
SJS Investment Consulting Inc.4$1.29K0.00%+3+300.0%Added
UMA Financial Services, Inc.4$1.29K0.00%+4New
Zions Bancorporation, National Association2$6440.00%+2New
Versant Capital Management, Inc2$6440.00%+2New
National Bank of Canada2$6410.00%+2New
Quadrant Capital Group LLC1$3230.00%+1New
Bogart Wealth, LLC1$3220.00%+1New
Hughes Financial Services, LLC1$3220.00%+1New
Activest Wealth Management0$00.00%−68−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−492,346−100.0%Sold out
Assenagon Asset Management S.A.0$00.00%−408,787−100.0%Sold out
Renaissance Technologies LLC0$00.00%−66,230−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−37,481−100.0%Sold out
Empowered Funds, LLC0$00.00%−36,852−100.0%Sold out
Readystate Asset Management LP0$00.00%−36,792−100.0%Sold out
Citadel Advisors LLC0$00.00%−34,917−100.0%Sold out
Caption Management, LLC0$00.00%−33,300−100.0%Sold out