Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opko Health, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 236
- +21 vs. Q4 2025
- Shares held
- 201.2M
- +34.3M (+20.5%) vs. Q4 2025
- Total value
- $229.4M
- +$19.5M (+9.3%) vs. Q4 2025
- New holders
- 44
- 59 more added
- Sold out
- 23
- 62 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Headlands Technologies LLC | 56,480 | $64.4K | 0.01% | −32,482−36.5% | Reduced |
| Private Advisor Group, LLC | 55,301 | $63.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $62.9K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 54,068 | $62.0K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 52,859 | $60.3K | 0.00% | −66,795−55.8% | Reduced |
| Mercer Global Advisors Inc | 52,832 | $60.2K | 0.00% | −6,194−10.5% | Reduced |
| First Manhattan Co | 52,150 | $59.5K | 0.00% | +400+0.8% | Added |
| Transcend Wealth Collective, LLC | 51,905 | $59.2K | 0.00% | −836−1.6% | Reduced |
| Farmers National Bank | 50,300 | $57.3K | 0.01% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 47,667 | $54.3K | 0.00% | −27,648−36.7% | Reduced |
| Brevan Howard Capital Management LP | 45,919 | $52.3K | 0.00% | −39,429−46.2% | Reduced |
| LGL Partners, LLC | 44,507 | $50.7K | 0.02% | +44,507 | New |
| Victory Capital Management Inc | 44,268 | $50.5K | 0.00% | −757−1.7% | Reduced |
| FMR LLC | 41,343 | $47.1K | 0.00% | +27,256+193.5% | Added |
| Group One Trading, L.P. | 40,662 | $46.4K | 0.00% | +40,662 | New |
| Captrust Financial Advisors | 40,306 | $45.9K | 0.00% | +186+0.5% | Added |
| Hollencrest Capital Management | 40,000 | $45.6K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 39,346 | $44.8K | 0.00% | −2,879−6.8% | Reduced |
| Brighton Jones LLC | 37,950 | $43.3K | 0.00% | +37,950 | New |
| Xponance, Inc. | 37,294 | $42.5K | 0.00% | +4,933+15.2% | Added |
| The PNC Financial Services Group, Inc. | 37,000 | $42.2K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 34,714 | $39.6K | 0.00% | +8,277+31.3% | Added |
| RSM US Wealth Management LLC | 33,757 | $38.5K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 33,676 | $38.4K | 0.00% | +17,134+103.6% | Added |
| HighTower Advisors, LLC | 33,311 | $38.0K | 0.00% | −4,142−11.1% | Reduced |
| Abel Hall, LLC | 33,271 | $37.9K | 0.01% | +33,271 | New |
| Raymond James Financial Inc | 32,624 | $37.2K | 0.00% | −6,120−15.8% | Reduced |
| Warren Averett Asset Management, LLC | 32,556 | $37.1K | 0.00% | −2,171−6.3% | Reduced |
| Operose Advisors LLC | 32,000 | $36.5K | 0.01% | 00.0% | Unchanged |
| STRS Ohio | 31,900 | $36.4K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 31,889 | $36.4K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 31,816 | $36.3K | 0.00% | −2,874−8.3% | Reduced |
| EP Wealth Advisors, LLC | 30,170 | $34.4K | 0.00% | +724+2.5% | Added |
| Wellington Grp LLC | 30,000 | $34.2K | 0.01% | −30,000−50.0% | Reduced |
| IPG Investment Advisors LLC | 30,000 | $34.2K | 0.01% | 00.0% | Unchanged |
| Apella Capital, LLC | 27,021 | $33.5K | 0.00% | +27,021 | New |
| Diversify Wealth Management, LLC | 30,000 | $33.3K | 0.00% | 00.0% | Unchanged |
| Swiss Life Asset Management Ltd | 28,488 | $32.5K | 0.00% | +9,324+48.7% | Added |
| LPL Financial LLC | 28,158 | $32.1K | 0.00% | +5,700+25.4% | Added |
| SlateStone Wealth, LLC | 25,770 | $29.0K | 0.00% | 00.0% | Unchanged |
| Arrow Financial Corp | 25,000 | $28.5K | 0.00% | 00.0% | Unchanged |
| Mirabella Financial Services LLP | 24,906 | $28.4K | 0.00% | −168,816−87.1% | Reduced |
| Zacks Investment Management | 24,665 | $28.1K | 0.00% | +3,343+15.7% | Added |
| Cerity Partners LLC | 23,471 | $26.8K | 0.00% | +6,089+35.0% | Added |
| Sax Wealth Advisors, LLC | 20,188 | $25.4K | 0.00% | −110−0.5% | Reduced |
| CIBC Asset Management Inc | 21,918 | $25.0K | 0.00% | 00.0% | Unchanged |
| CIBC Bancorp USA Inc. | 20,721 | $23.6K | 0.00% | +20,721 | New |
| Capital Advisors Inc | 20,000 | $22.8K | 0.00% | −350,000−94.6% | Reduced |
| Spartan Wealth Advisory Services LLC | 20,000 | $22.8K | 0.00% | +20,000 | New |
| Cumberland Advisors Inc | 19,500 | $22.2K | 0.01% | 00.0% | Unchanged |
| Westmount Partners, LLC | 18,550 | $21.1K | 0.01% | 00.0% | Unchanged |
| Principal Financial Group Inc | 17,740 | $20.2K | 0.00% | −12−0.1% | Reduced |
| CIBC World Markets Inc. | 17,228 | $19.6K | 0.00% | 00.0% | Unchanged |
| Blueshift Asset Management, LLC | 17,036 | $19.4K | 0.01% | +17,036 | New |
| Shufro Rose & Co LLC | 17,000 | $19.4K | 0.00% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 16,770 | $19.1K | 0.00% | 00.0% | Unchanged |
| SIH Partners, LLLP | 16,687 | $19.0K | 0.00% | −87,647−84.0% | Reduced |
| Jones Financial Companies LLLP | 16,675 | $18.7K | 0.00% | +2,550+18.1% | Added |
| Commons Capital, LLC | 16,300 | $18.6K | 0.02% | 00.0% | Unchanged |
| Sequoia Financial Advisors, LLC | 16,264 | $18.5K | 0.00% | +16,264 | New |
| Sigma Planning Corp | 15,807 | $18.0K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 15,549 | $17.7K | 0.00% | +191+1.2% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,823 | $16.9K | 0.00% | 00.0% | Unchanged |
| Colony Family Offices, LLC | 14,729 | $16.8K | 0.00% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 14,775 | $16.7K | 0.00% | +11,483+348.8% | Added |
| Mill Creek Capital Advisors, LLC | 14,383 | $16.4K | 0.00% | +2,000+16.2% | Added |
| Sterling Capital Management LLC | 13,716 | $15.6K | 0.00% | −10,004−42.2% | Reduced |
| Moody National Bank Trust Division | 13,554 | $15.5K | 0.00% | +13,554 | New |
| Key Financial Inc | 13,250 | $15.1K | 0.00% | −2,000−13.1% | Reduced |
| Amalgamated Bank | 12,929 | $15.0K | 0.00% | 00.0% | Unchanged |
| Atomi Financial Group, Inc. | 12,501 | $14.3K | 0.00% | +1,001+8.7% | Added |
| Traphagen Investment Advisors LLC | 11,680 | $13.3K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 11,661 | $13.3K | 0.00% | +3,510+43.1% | Added |
| JustInvest LLC | 11,596 | $13.2K | 0.00% | +11,596 | New |
| Formidable Asset Management, LLC | 10,296 | $13.0K | 0.00% | −1,000−8.9% | Reduced |
| Colony Group, LLC | 11,100 | $12.7K | 0.00% | +11,100 | New |
| HBK Sorce Advisory LLC | 11,057 | $12.6K | 0.00% | 00.0% | Unchanged |
| IMC-Chicago, LLC | 10,874 | $12.4K | 0.00% | +10,874 | New |
| Frec Markets, Inc. | 10,542 | $12.0K | 0.00% | +10,542 | New |
| SEI Investments Co | 10,163 | $11.6K | 0.00% | 00.0% | Unchanged |
| Diversified Trust Co | 10,122 | $11.5K | 0.00% | −252−2.4% | Reduced |
| First Affirmative Financial Network | 10,108 | $11.5K | 0.00% | +10,108 | New |
| KLCM Advisors, Inc. | 10,000 | $11.4K | 0.00% | 00.0% | Unchanged |
| MRP Capital Investments, LLC | 10,000 | $11.4K | 0.01% | 00.0% | Unchanged |
| Greenbush Financial Group, LLC | 10,000 | $11.4K | 0.00% | 00.0% | Unchanged |
| Sanibel Captiva Trust Company, Inc. | 10,000 | $11.4K | 0.00% | +10,000 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 9,221 | $10.5K | 0.00% | +3,176+52.5% | Added |
| Quantbot Technologies LP | 8,902 | $10.1K | 0.00% | −113,845−92.7% | Reduced |
| Aventura Private Wealth, LLC | 8,400 | $9.58K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 7,320 | $8.34K | 0.00% | −86,561−92.2% | Reduced |
| Steward Partners Investment Advisory, LLC | 7,110 | $8.11K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 5,200 | $5.93K | 0.00% | −1,000−16.1% | Reduced |
| Aquatic Capital Management LLC | 4,166 | $4.75K | 0.00% | +4,166 | New |
| Parallel Advisors, LLC | 3,649 | $4.16K | 0.00% | +3,649 | New |
| EverSource Wealth Advisors, LLC | 3,534 | $4.03K | 0.00% | −2,091−37.2% | Reduced |
| Nisa Investment Advisors, LLC | 3,388 | $3.86K | 0.00% | +2,076+158.2% | Added |
| Gables Capital Management Inc. | 3,000 | $3.42K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 2,729 | $3.08K | 0.00% | +2,621+2,426.9% | Added |
| Smartleaf Asset Management LLC | 2,757 | $3.03K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 2,207 | $2.52K | 0.00% | +491+28.6% | Added |