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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Opko Health, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
206
−22 vs. Q2 2021
Shares held
183.2M
−7.45M (−3.9%) vs. Q2 2021
Total value
$668.9M
−$103.2M (−13.4%) vs. Q2 2021
New holders
19
51 more added
Sold out
41
57 more reduced

6 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 206 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ3 2021: $668.9M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q2 2021.

Institutions holding OPK in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc35,465,884$129.4M0.00%−266,596−0.7%Reduced
BlackRock Inc.34,825,680$127.1M0.00%−610,701−1.7%Reduced
State Street Corp23,374,615$85.3M0.00%+2,577,407+12.4%Added
Oracle Investment Management Inc12,819,073$46.8M5.88%00.0%Unchanged
Geode Capital Management, LLC7,728,730$28.2M0.00%−53,188−0.7%Reduced
Northern Trust Corp6,311,950$23.0M0.00%−248,032−3.8%Reduced
Dimensional Fund Advisors LP4,473,095$16.3M0.01%−2,759,184−38.2%Reduced
Prudential Financial Inc3,781,819$13.8M0.02%+529,609+16.3%Added
Charles Schwab Investment Management Inc3,550,759$13.0M0.00%−90,897−2.5%Reduced
Norges Bank3,060,935$11.2M0.00%−139,462−4.4%Reduced
Susquehanna International Group, LLP3,007,263$11.0M0.01%+645,080+27.3%Added
Nuveen Asset Management, LLC2,835,745$10.3M0.00%−515,132−15.4%Reduced
Invesco Ltd.2,639,880$9.64M0.00%+103,959+4.1%Added
D. E. Shaw & Co., Inc.2,077,854$7.58M0.01%−478,728−18.7%Reduced
Goldman Sachs Group Inc2,014,645$7.35M0.00%−2,671,054−57.0%Reduced
Bank of New York Mellon Corp1,954,609$7.13M0.00%+69,458+3.7%Added
Hennion & Walsh Asset Management, Inc.1,612,067$5.88M0.31%−75,255−4.5%Reduced
Nordea Investment Management AB1,328,842$4.92M0.01%−17,025−1.3%Reduced
JPMorgan Chase & Co1,276,574$4.66M0.00%+369,649+40.8%Added
Morgan Stanley1,123,865$4.10M0.00%−259,666−18.8%Reduced
Wells Fargo & Company1,020,452$3.73M0.00%+41,995+4.3%Added
Principal Financial Group Inc994,872$3.63M0.00%+1,938+0.2%Added
Connor, Clark & Lunn Investment Management Ltd.989,130$3.61M0.02%+187,633+23.4%Added
First Trust Advisors LP974,932$3.56M0.00%−494,162−33.6%Reduced
Swiss National Bank960,000$3.50M0.00%00.0%Unchanged
Renaissance Technologies LLC910,153$3.32M0.00%−329,790−26.6%Reduced
Alliancebernstein L.P.897,900$3.28M0.00%+300,000+50.2%Added
Rafferty Asset Management, LLC870,666$3.18M0.02%+169,452+24.2%Added
UBS Group AG817,277$2.98M0.00%+30,948+3.9%Added
AWM Investment Company, Inc.800,000$2.92M0.29%00.0%Unchanged
Landscape Capital Management, L.L.C.768,807$2.81M0.39%−80,959−9.5%Reduced
Victory Capital Management Inc699,856$2.55M0.00%+57,252+8.9%Added
Rhumbline Advisers620,856$2.27M0.00%+18,201+3.0%Added
Citigroup Inc613,490$2.24M0.00%−555,806−47.5%Reduced
California State Teachers Retirement System572,908$2.09M0.00%+30,959+5.7%Added
Jupiter Asset Management Ltd564,018$2.05M0.02%+383,792+213.0%Added
State of Wisconsin Investment Board535,300$1.95M0.00%−93,400−14.9%Reduced
Millennium Management LLC479,760$1.75M0.00%+45,896+10.6%Added
Jane Street Group, LLC478,653$1.75M0.00%−63,408−11.7%Reduced
Zebra Capital Management LLC469,083$1.71M2.07%+469,083New
ExodusPoint Capital Management, LP436,614$1.59M0.02%−207,744−32.2%Reduced
UBS Asset Management Americas Inc431,092$1.57M0.00%+4,577+1.1%Added
Credit Suisse AG421,423$1.54M0.00%+34,609+8.9%Added
Commonwealth Equity Services, LLC403,825$1.47M0.00%−350.0%Reduced
Group One Trading, L.P.374,170$1.37M0.03%+99,836+36.4%Added
Jump Financial, LLC367,315$1.34M0.10%+367,315New
Legal & General Group Plc347,372$1.27M0.00%+90,502+35.2%Added
Deutsche Bank AG331,969$1.21M0.00%−3,559−1.1%Reduced
AQR Capital Management LLC300,507$1.10M0.00%−144,214−32.4%Reduced
Cambridge Investment Research Advisors, Inc.287,074$1.05M0.01%−6,867−2.3%Reduced
Price T Rowe Associates Inc284,674$1.04M0.00%00.0%Unchanged
Parametric Portfolio Associates LLC273,521$998.0K0.00%−37,590−12.1%Reduced
Phoenix Holdings Ltd.266,862$974.0K0.02%00.0%Unchanged
New York State Common Retirement Fund265,546$969.0K0.00%−67,030−20.2%Reduced
SG Americas Securities, LLC259,747$948.0K0.01%+190,433+274.7%Added
ETF Managers Group, LLC248,716$905.0K0.02%+51,060+25.8%Added
X-Square Capital, LLC231,465$845.0K0.44%00.0%Unchanged
Gabelli Funds LLC221,000$807.0K0.01%00.0%Unchanged
Teton Advisors, Inc.220,000$803.0K0.12%00.0%Unchanged
Bank of America Corp219,368$800.0K0.00%+66,822+43.8%Added
Barclays PLC218,940$799.0K0.00%+108,746+98.7%Added
American International Group, Inc.218,703$798.0K0.00%−1,579−0.7%Reduced
Manufacturers Life Insurance Company, The212,578$776.0K0.00%−13,868−6.1%Reduced
Citadel Advisors LLC211,672$773.0K0.00%−80,259−27.5%Reduced
Gamco Investors, Inc. Et Al200,000$730.0K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.197,250$719.0K0.00%−2,100−1.1%Reduced
Susquehanna Fundamental Investments, LLC178,440$651.0K0.01%+116,379+187.5%Added
State Board of Administration of Florida Retirement System176,020$642.0K0.00%00.0%Unchanged
Capital Advisors Inc164,625$601.0K0.02%−4,000−2.4%Reduced
Voya Investment Management LLC158,487$578.0K0.00%00.0%Unchanged
Ameriprise Financial Inc145,229$530.0K0.00%−112,000−43.5%Reduced
Virginia Retirement Systems Et Al144,700$528.0K0.01%−20,900−12.6%Reduced
Royal Bank of Canada144,699$528.0K0.00%+31,767+28.1%Added
MetLife Investment Management140,506$512.8K0.00%+20,154+16.7%Added
BNP Paribas Arbitrage, SA139,221$508.2K0.00%+32,660+30.6%Added
Occudo Quantitative Strategies LP135,902$496.0K0.06%+52,787+63.5%Added
AE Wealth Management LLC122,348$447.0K0.00%−2,616−2.1%Reduced
Arizona State Retirement System118,654$433.0K0.00%+267+0.2%Added
Ergoteles LLC113,021$413.0K0.02%+113,021New
Sax Wealth Advisors, LLC109,601$400.0K0.09%+109,601New
Metropolitan Life Insurance Co107,781$393.4K0.01%+9,693+9.9%Added
Matrix Private Capital Group LLC106,086$387.0K0.20%00.0%Unchanged
Cubist Systematic Strategies, LLC94,825$346.0K0.00%−25,810−21.4%Reduced
Hussman Strategic Advisors, Inc.93,000$339.0K0.07%−51,000−35.4%Reduced
Tower Research Capital LLC (TRC)86,175$315.0K0.01%+57,520+200.7%Added
Creative Planning85,667$313.0K0.00%+5,273+6.6%Added
Engineers Gate Manager LP84,171$307.0K0.02%+6,385+8.2%Added
DuPont Capital Management Corp80,363$293.0K0.01%−11,358−12.4%Reduced
Raymond James & Associates79,986$292.0K0.00%+4,672+6.2%Added
Handelsbanken Fonder AB79,421$290.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas70,234$256.0K0.00%+12,793+22.3%Added
Sowell Financial Services LLC69,600$254.0K0.02%00.0%Unchanged
Norris Perne & French LLP67,000$245.0K0.02%+7,000+11.7%Added
Fairfield, Bush & Co.64,650$236.0K0.08%−12,545−16.3%Reduced
Farmers National Bank57,500$227.1K0.09%+57,500New
Public Employees Retirement Association of Colorado61,502$224.0K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC61,000$223.0K0.02%00.0%Unchanged
Raymond James Financial Services Advisors, Inc.58,060$212.0K0.00%+2,854+5.2%Added
Shell Asset Management Co56,510$206.0K0.00%−2,430−4.1%Reduced
HSBC Holdings PLC55,422$204.0K0.00%−12,922−18.9%Reduced