Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 225 institutions reported holding it in 13F filings for Q2 2026, worth $368.6M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Opko Health, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 225
- −9 vs. Q1 2026
- Shares held
- 202.8M
- +2.06M (+1.0%) vs. Q1 2026
- Total value
- $368.6M
- +$77.6M (+26.7%) vs. Q1 2026
- New holders
- 23
- 76 more added
- Sold out
- 32
- 51 more reduced
6 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $368.6M |
| Q1 2026 | 240 | $291.5M |
| Q4 2025 | 225 | $308.6M |
| Q3 2025 | 237 | $371.8M |
| Q2 2025 | 226 | $328.7M |
| Q1 2025 | 258 | $457.6M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $282.2M |
| Q2 2024 | 232 | $229.3M |
| Q1 2024 | 224 | $195.8M |
| Q4 2023 | 218 | $262.3M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.9M |
| Q1 2023 | 227 | $259.5M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $350.3M |
| Q2 2022 | 231 | $480.5M |
| Q1 2022 | 229 | $672.5M |
| Q4 2021 | 236 | $939.9M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $774.5M |
| Q1 2021 | 239 | $817.2M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 47,791,243 | $73.6M | 0.67% | 00.0% | Unchanged |
| BlackRock, Inc. | 36,978,893 | $55.5M | 0.00% | +746,670+2.1% | Added |
| Vanguard Capital Management LLC | 14,968,930 | $22.5M | 0.00% | +469,766+3.2% | Added |
| Vanguard Portfolio Management LLC | 14,934,924 | $22.4M | 0.00% | +165,205+1.1% | Added |
| Whitefort Capital Management, LP | 4,511,412 | $20.8M | 5.14% | +258,072+6.1% | Added |
| Wolverine Asset Management LLC | – | $20.4M | 0.27% | – | – |
| Geode Capital Management, LLC | 11,581,027 | $17.4M | 0.00% | +279,526+2.5% | Added |
| State Street Corp | 10,309,070 | $15.5M | 0.00% | +807,693+8.5% | Added |
| PenderFund Capital Management Ltd. | – | $12.8M | 1.64% | – | – |
| Goldman Sachs Group Inc | 7,035,492 | $10.6M | 0.00% | −639,534−8.3% | Reduced |
| Zazove Associates LLC | 100,000 | $9.14M | 0.75% | −200,000−66.7% | Reduced |
| UBS Group AG | 5,006,284 | $7.51M | 0.00% | −1,065,148−17.5% | Reduced |
| Northern Trust Corp | 3,756,163 | $5.63M | 0.00% | +136,817+3.8% | Added |
| Highbridge Capital Management LLC | 3,593,925 | $5.43M | 0.19% | +3,593,925 | New |
| Charles Schwab Investment Management Inc | 3,596,980 | $5.40M | 0.00% | +22,941+0.6% | Added |
| Vanguard Fiduciary Trust Co | 2,706,235 | $4.06M | 0.00% | −35,782−1.3% | Reduced |
| Linden Advisors LP | – | $3.37M | 0.02% | – | – |
| AWM Investment Company, Inc. | 2,110,000 | $3.17M | 0.27% | +10,000+0.5% | Added |
| Morgan Stanley | 1,975,027 | $2.96M | 0.00% | +778,940+65.1% | Added |
| Citadel Advisors LLC | 1,420,922 | $2.13M | 0.00% | −658,625−31.7% | Reduced |
| FMR LLC | 15,336 | $2.12M | 0.00% | −26,007−62.9% | Reduced |
| Washington Growth Strategies LLC | 1,356,124 | $2.03M | 1.13% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 1,329,974 | $1.99M | 0.00% | +49,932+3.9% | Added |
| Dimensional Fund Advisors LP | 1,267,741 | $1.90M | 0.00% | −292,259−18.7% | Reduced |
| Y.D. More Investments Ltd | 1,257,568 | $1.88M | 0.06% | −41,905−3.2% | Reduced |
| AQR Capital Management LLC | 1,239,399 | $1.86M | 0.00% | +475,809+62.3% | Added |
| OP Asset Management Ltd | 1,159,647 | $1.74M | 0.02% | +57,393+5.2% | Added |
| Voya Investment Management LLC | 1,094,111 | $1.64M | 0.00% | −66,816−5.8% | Reduced |
| California State Teachers Retirement System | 961,484 | $1.44M | 0.00% | +547,447+132.2% | Added |
| Clearstead Advisors, LLC | 883,288 | $1.32M | 0.01% | −831−0.1% | Reduced |
| Nuveen, LLC | 863,035 | $1.29M | 0.00% | +16,042+1.9% | Added |
| Bank of America Corp | 795,716 | $1.19M | 0.00% | −346,133−30.3% | Reduced |
| Swiss National Bank | 761,455 | $1.14M | 0.00% | −84,300−10.0% | Reduced |
| JPMorgan Chase & Co | 168,305 | $1.13M | 0.00% | −340,179−66.9% | Reduced |
| Invesco Ltd. | 685,076 | $1.03M | 0.00% | −108,093−13.6% | Reduced |
| Susquehanna International Group, LLP | 623,561 | $935.3K | 0.00% | +232,045+59.3% | Added |
| PFG Investments, LLC | 610,491 | $915.7K | 0.04% | −502,285−45.1% | Reduced |
| UBS Asset Management Americas Inc | 574,107 | $861.2K | 0.00% | −100,741−14.9% | Reduced |
| Assenagon Asset Management S.A. | 570,678 | $851.0K | 0.00% | −81,388−12.5% | Reduced |
| Kovack Advisors, Inc. | 536,202 | $804.3K | 0.04% | +76,502+16.6% | Added |
| Rhumbline Advisers | 498,861 | $748.3K | 0.00% | +1,621+0.3% | Added |
| Price T Rowe Associates Inc | 455,748 | $684.0K | 0.00% | +51,096+12.6% | Added |
| Van Eck Associates Corp | 438,645 | $658.0K | 0.00% | +278,549+174.0% | Added |
| Commonwealth Equity Services, LLC | 431,894 | $647.8K | 0.00% | +988+0.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 412,051 | $618.1K | 0.00% | −110,855−21.2% | Reduced |
| Deutsche Bank AG | 398,603 | $597.9K | 0.00% | +27,655+7.5% | Added |
| Algert Global LLC | 397,030 | $595.5K | 0.01% | +397,030 | New |
| Wells Fargo & Company | 354,039 | $531.1K | 0.00% | +191,430+117.7% | Added |
| Legal & General Group Plc | 346,787 | $520.2K | 0.00% | +3,313+1.0% | Added |
| Alliancebernstein L.P. | 442,680 | $504.7K | 0.00% | +19,490+4.6% | Added |
| Vanguard Asset Management, Ltd | 294,013 | $441.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 289,812 | $435.0K | 0.00% | +69,818+31.7% | Added |
| XTX Topco Ltd | 286,173 | $429.3K | 0.01% | −144,793−33.6% | Reduced |
| Creative Planning | 246,065 | $369.1K | 0.00% | +69,080+39.0% | Added |
| Tudor Investment Corp Et Al | 244,821 | $367.2K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 229,454 | $344.2K | 0.00% | −884,921−79.4% | Reduced |
| MetLife Investment Management | 226,799 | $340.2K | 0.00% | +22,061+10.8% | Added |
| Russell Investments Group, Ltd. | 215,820 | $323.7K | 0.00% | +184,004+578.3% | Added |
| Jupiter Topco LLC | 206,314 | $310.5K | 0.00% | +206,314 | New |
| Citigroup Inc | 199,824 | $299.7K | 0.00% | +166,148+493.4% | Added |
| HSBC Holdings PLC | 199,966 | $298.9K | 0.00% | −38,315−16.1% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 185,564 | $278.3K | 0.00% | −12,342−6.2% | Reduced |
| Vanguard Global Advisers, LLC | 181,766 | $272.6K | 0.00% | 00.0% | Unchanged |
| RPg Family Wealth Advisory, LLC | 177,238 | $265.9K | 0.02% | +88,619+100.0% | Added |
| State Board of Administration of Florida Retirement System | 176,260 | $264.4K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 175,801 | $263.7K | 0.00% | +5,801+3.4% | Added |
| Gamco Investors, Inc. Et Al | 175,000 | $262.5K | 0.00% | 00.0% | Unchanged |
| Gabelli Funds LLC | 170,000 | $255.0K | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 170,000 | $255.0K | 0.00% | +41,209+32.0% | Added |
| Ieq Capital, LLC | 169,425 | $254.1K | 0.00% | +76,203+81.7% | Added |
| Cambridge Investment Research Advisors, Inc. | 167,350 | $252.0K | 0.00% | +77,071+85.4% | Added |
| 360 Financial, Inc. | 150,300 | $225.4K | 0.06% | +53,000+54.5% | Added |
| Point72 Asset Management, L.P. | 145,234 | $217.9K | 0.00% | +51,899+55.6% | Added |
| Teton Advisors, LLC | 140,000 | $210.0K | 0.12% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 132,463 | $198.7K | 0.00% | +30,066+29.4% | Added |
| Manufacturers Life Insurance Company, The | 119,132 | $178.7K | 0.00% | −2,996−2.5% | Reduced |
| Highline Wealth Partners LLC | 116,680 | $175.0K | 0.04% | 00.0% | Unchanged |
| State of Wyoming | 116,489 | $174.7K | 0.02% | −50,531−30.3% | Reduced |
| New York State Common Retirement Fund | 114,301 | $171.5K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 113,848 | $171.0K | 0.00% | +26,002+29.6% | Added |
| Glenmede Trust Co NA | 112,750 | $169.1K | 0.00% | 00.0% | Unchanged |
| Vanguard Investments Australia, Ltd. | 110,958 | $166.4K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 107,989 | $162.0K | 0.02% | +51,509+91.2% | Added |
| Arizona State Retirement System | 104,725 | $157.1K | 0.00% | −11,253−9.7% | Reduced |
| Barclays PLC | 99,596 | $149.4K | 0.00% | −38,704−28.0% | Reduced |
| Ameriprise Financial Inc | 94,061 | $141.1K | 0.00% | −2,661−2.8% | Reduced |
| SRS Capital Advisors, Inc. | 93,616 | $140.4K | 0.00% | +93,323+31,850.9% | Added |
| Cerity Partners LLC | 91,099 | $136.7K | 0.00% | +67,628+288.1% | Added |
| KLP Kapitalforvaltning AS | 90,700 | $136.1K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 85,883 | $128.8K | 0.00% | −39,931−31.7% | Reduced |
| Allied Private Wealth LLC | 91,137 | $128.5K | 0.08% | +91,137 | New |
| Mercer Global Advisors Inc | 76,808 | $115.2K | 0.00% | +23,976+45.4% | Added |
| Wealth Enhancement Advisory Services, LLC | 83,994 | $113.4K | 0.00% | +21,629+34.7% | Added |
| Millennium Management LLC | 72,301 | $108.5K | 0.00% | +72,301 | New |
| Advisor Group Holdings, Inc. | 69,567 | $104.3K | 0.00% | +21,900+45.9% | Added |
| Prudential Financial Inc | 68,976 | $103.5K | 0.00% | +3,420+5.2% | Added |
| Cascade Financial Partners, LLC | 66,490 | $99.7K | 0.01% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 65,495 | $98.2K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 63,704 | $95.6K | 0.00% | +23,398+58.1% | Added |
| Public Employees Retirement Association of Colorado | 61,502 | $92.0K | 0.00% | 00.0% | Unchanged |