Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Opko Health, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- −10 vs. Q2 2022
- Shares held
- 185.0M
- −4.73M (−2.5%) vs. Q2 2022
- Total value
- $349.6M
- −$130.3M (−27.1%) vs. Q2 2022
- New holders
- 22
- 68 more added
- Sold out
- 32
- 57 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 40,284,773 | $76.1M | 0.00% | −2,296,471−5.4% | Reduced |
| BlackRock Inc. | 34,508,003 | $65.2M | 0.00% | −502,344−1.4% | Reduced |
| Dimensional Fund Advisors LP | 10,823,641 | $20.5M | 0.01% | +1,744,961+19.2% | Added |
| State Street Corp | 10,374,273 | $19.6M | 0.00% | +507,764+5.1% | Added |
| Geode Capital Management, LLC | 7,829,188 | $14.8M | 0.00% | +200,456+2.6% | Added |
| D. E. Shaw & Co., Inc. | 5,968,306 | $11.3M | 0.02% | −397,910−6.3% | Reduced |
| Oracle Investment Management Inc | 5,102,756 | $9.64M | 5.53% | −2,150,000−29.6% | Reduced |
| Northern Trust Corp | 3,905,354 | $7.38M | 0.00% | −1,162,543−22.9% | Reduced |
| Charles Schwab Investment Management Inc | 3,813,530 | $7.21M | 0.00% | +420,857+12.4% | Added |
| Invesco Ltd. | 3,372,129 | $6.37M | 0.00% | +706,353+26.5% | Added |
| Norges Bank | 3,233,385 | $6.11M | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 2,887,369 | $5.46M | 0.02% | +1,191,429+70.3% | Added |
| Renaissance Technologies LLC | 2,836,343 | $5.36M | 0.01% | −1,053,829−27.1% | Reduced |
| Goldman Sachs Group Inc | 2,806,554 | $5.30M | 0.00% | +185,071+7.1% | Added |
| JPMorgan Chase & Co | 2,374,176 | $4.49M | 0.00% | +344,713+17.0% | Added |
| Deutsche Bank AG | 2,280,181 | $4.31M | 0.00% | +751,958+49.2% | Added |
| Nuveen Asset Management, LLC | 2,201,636 | $4.16M | 0.00% | −483,570−18.0% | Reduced |
| Citigroup Inc | 2,142,392 | $4.05M | 0.01% | −25,221−1.2% | Reduced |
| Millennium Management LLC | 2,142,184 | $4.05M | 0.01% | −5,248,251−71.0% | Reduced |
| Two Sigma Advisers, LP | 2,122,397 | $4.01M | 0.01% | +1,275,600+150.6% | Added |
| Bank of New York Mellon Corp | 2,043,330 | $3.86M | 0.00% | +119,338+6.2% | Added |
| Voya Investment Management LLC | 1,621,430 | $3.06M | 0.00% | +1,464,669+934.3% | Added |
| Phoenix Holdings Ltd. | 1,628,862 | $3.05M | 0.07% | +404,800+33.1% | Added |
| Morgan Stanley | 1,347,909 | $2.55M | 0.00% | −14,635−1.1% | Reduced |
| Nordea Investment Management AB | 1,290,609 | $2.45M | 0.00% | −43,926−3.3% | Reduced |
| Susquehanna International Group, LLP | 1,235,957 | $2.34M | 0.00% | −62,554−4.8% | Reduced |
| Jane Street Group, LLC | 1,086,733 | $2.05M | 0.00% | +489,131+81.8% | Added |
| Prudential Financial Inc | 1,049,591 | $1.98M | 0.00% | −345,885−24.8% | Reduced |
| Swiss National Bank | 1,047,200 | $1.98M | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 850,208 | $1.61M | 0.00% | −196,210−18.8% | Reduced |
| Group One Trading, L.P. | 835,828 | $1.58M | 0.05% | +455,845+120.0% | Added |
| AWM Investment Company, Inc. | 800,000 | $1.51M | 0.23% | 00.0% | Unchanged |
| Jupiter Asset Management Ltd | 765,198 | $1.45M | 0.02% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 757,240 | $1.43M | 0.01% | +232,618+44.3% | Added |
| Rhumbline Advisers | 648,706 | $1.23M | 0.00% | +42,521+7.0% | Added |
| Alliancebernstein L.P. | 606,000 | $1.15M | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 540,577 | $1.02M | 0.00% | −8,883−1.6% | Reduced |
| Schonfeld Strategic Advisors LLC | 478,378 | $904.0K | 0.01% | +204,183+74.5% | Added |
| Cubist Systematic Strategies, LLC | 477,599 | $903.0K | 0.01% | −355,379−42.7% | Reduced |
| Candriam Luxembourg S.C.A. | 452,348 | $855.0K | 0.01% | +452,348 | New |
| State of Wisconsin Investment Board | 450,334 | $851.0K | 0.00% | −24,303−5.1% | Reduced |
| Graham Capital Management, L.P. | 450,638 | $851.0K | 0.04% | +258,286+134.3% | Added |
| HRT Financial LP | 445,083 | $841.0K | 0.01% | +170,122+61.9% | Added |
| Alps Advisors Inc | 421,404 | $796.0K | 0.01% | +16,862+4.2% | Added |
| Credit Suisse AG | 409,282 | $773.0K | 0.00% | +4,549+1.1% | Added |
| Commonwealth Equity Services, LLC | 407,607 | $770.0K | 0.00% | +1,876+0.5% | Added |
| Legal & General Group Plc | 376,343 | $712.0K | 0.00% | +29,143+8.4% | Added |
| Occudo Quantitative Strategies LP | 349,563 | $661.0K | 0.05% | +274,160+363.6% | Added |
| Tudor Investment Corp Et Al | 341,105 | $645.0K | 0.02% | +308,800+955.9% | Added |
| UBS Asset Management Americas Inc | 334,071 | $631.4K | 0.00% | −116,125−25.8% | Reduced |
| Victory Capital Management Inc | 333,249 | $630.0K | 0.00% | −4,309−1.3% | Reduced |
| AQR Capital Management LLC | 331,249 | $626.0K | 0.00% | +162,396+96.2% | Added |
| Engineers Gate Manager LP | 313,110 | $592.0K | 0.04% | +88,486+39.4% | Added |
| Price T Rowe Associates Inc | 272,058 | $515.0K | 0.00% | −3,543−1.3% | Reduced |
| AXA S.A. | 261,925 | $495.0K | 0.00% | +13,900+5.6% | Added |
| New York State Common Retirement Fund | 261,700 | $495.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 246,922 | $466.0K | 0.00% | +56,706+29.8% | Added |
| ETF Managers Group, LLC | 227,801 | $431.0K | 0.01% | +12,506+5.8% | Added |
| Hennion & Walsh Asset Management, Inc. | 221,951 | $419.0K | 0.03% | +55,248+33.1% | Added |
| UBS Group AG | 218,538 | $413.0K | 0.00% | +47,049+27.4% | Added |
| MetLife Investment Management | 214,381 | $405.2K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 210,316 | $397.0K | 0.00% | −51,125−19.6% | Reduced |
| Teton Advisors, Inc. | 210,000 | $397.0K | 0.10% | −10,000−4.5% | Reduced |
| X-Square Capital, LLC | 205,396 | $388.0K | 0.25% | 00.0% | Unchanged |
| Principal Financial Group Inc | 203,567 | $385.0K | 0.00% | −121,918−37.5% | Reduced |
| Gabelli Funds LLC | 200,000 | $378.0K | 0.00% | −21,000−9.5% | Reduced |
| Gamco Investors, Inc. Et Al | 200,000 | $378.0K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 191,675 | $362.0K | 0.00% | +2,707+1.4% | Added |
| BNP Paribas Arbitrage, SA | 190,685 | $360.4K | 0.00% | +83,717+78.3% | Added |
| First Trust Advisors LP | 190,553 | $360.0K | 0.00% | +21,846+12.9% | Added |
| State Board of Administration of Florida Retirement System | 176,020 | $333.0K | 0.00% | −170,641−49.2% | Reduced |
| Manufacturers Life Insurance Company, The | 170,750 | $322.7K | 0.00% | −1,869−1.1% | Reduced |
| Advisor Group Holdings, Inc. | 151,267 | $287.0K | 0.00% | −2,973−1.9% | Reduced |
| Capital Advisors Inc | 164,625 | $285.0K | 0.01% | +164,625 | New |
| Bank of America Corp | 149,557 | $283.0K | 0.00% | −1,370−0.9% | Reduced |
| New York Life Investment Management LLC | 146,311 | $277.0K | 0.00% | +10,747+7.9% | Added |
| Van Eck Associates Corp | 141,935 | $268.0K | 0.00% | −17,744−11.1% | Reduced |
| SG Americas Securities, LLC | 137,544 | $260.0K | 0.00% | −20,694−13.1% | Reduced |
| Wilbanks Smith & Thomas Asset Management LLC | 135,976 | $257.0K | 0.01% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 131,279 | $248.0K | 0.00% | +400.0% | Added |
| Arizona State Retirement System | 120,370 | $227.0K | 0.00% | +351+0.3% | Added |
| Csenge Advisory Group | 117,000 | $221.0K | 0.02% | 00.0% | Unchanged |
| Highline Wealth Partners LLC | 106,680 | $201.6K | 0.16% | +106,680 | New |
| Altshuler Shaham Ltd | 62,428 | $196.0K | 0.00% | +62,428 | New |
| Handelsbanken Fonder AB | 101,621 | $192.0K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 101,051 | $190.0K | 0.01% | −90,917−47.4% | Reduced |
| Intrepid Capital Management Inc | 100,000 | $189.0K | 0.15% | +100,000 | New |
| Ergoteles LLC | 97,530 | $184.0K | 0.01% | +69,491+247.8% | Added |
| Creative Planning | 94,697 | $179.0K | 0.00% | +5,487+6.2% | Added |
| Dynamic Technology Lab Private Ltd | 91,634 | $173.0K | 0.02% | +29,392+47.2% | Added |
| Great West Life Assurance Co | 91,094 | $171.0K | 0.00% | +66,990+277.9% | Added |
| Janus Henderson Group PLC | 87,861 | $166.0K | 0.00% | −1,884−2.1% | Reduced |
| Weiss Multi-Strategy Advisers LLC | 85,000 | $161.0K | 0.00% | −190,000−69.1% | Reduced |
| Hollencrest Capital Management | 83,980 | $159.0K | 0.02% | 00.0% | Unchanged |
| Caption Management, LLC | 80,000 | $151.0K | 0.03% | +58,559+273.1% | Added |
| Shell Asset Management Co | 78,576 | $149.0K | 0.01% | +29,030+58.6% | Added |
| AE Wealth Management LLC | 78,313 | $148.0K | 0.00% | −1,000−1.3% | Reduced |
| Wells Fargo & Company | 73,391 | $139.0K | 0.00% | −9,714−11.7% | Reduced |
| XTX Topco Ltd | 71,440 | $135.0K | 0.03% | +40,252+129.1% | Added |
| BDO Wealth Advisors, LLC | 70,000 | $132.0K | 0.02% | 00.0% | Unchanged |