Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Opko Health, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 229
- −5 vs. Q4 2021
- Shares held
- 195.0M
- +4.82M (+2.5%) vs. Q4 2021
- Total value
- $671.0M
- −$243.7M (−26.6%) vs. Q4 2021
- New holders
- 35
- 54 more added
- Sold out
- 40
- 73 more reduced
2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 36,072,131 | $124.1M | 0.00% | +346,707+1.0% | Added |
| BlackRock Inc. | 33,870,368 | $116.5M | 0.00% | −520,544−1.5% | Reduced |
| State Street Corp | 27,688,831 | $95.3M | 0.00% | +10,014,088+56.7% | Added |
| Oracle Investment Management Inc | 8,985,756 | $30.9M | 6.22% | −3,233,317−26.5% | Reduced |
| Geode Capital Management, LLC | 7,767,491 | $26.7M | 0.00% | +37,079+0.5% | Added |
| Dimensional Fund Advisors LP | 7,184,414 | $24.7M | 0.01% | +3,037,320+73.2% | Added |
| Northern Trust Corp | 5,734,926 | $19.7M | 0.00% | −500,674−8.0% | Reduced |
| D. E. Shaw & Co., Inc. | 5,375,226 | $18.5M | 0.02% | +1,294,225+31.7% | Added |
| Charles Schwab Investment Management Inc | 3,870,903 | $13.3M | 0.00% | +296,038+8.3% | Added |
| Norges Bank | 3,832,941 | $13.2M | 0.00% | −443,442−10.4% | Reduced |
| Nuveen Asset Management, LLC | 3,493,482 | $12.5M | 0.00% | +1,2720.0% | Added |
| Goldman Sachs Group Inc | 3,001,411 | $10.3M | 0.00% | −858,033−22.2% | Reduced |
| JPMorgan Chase & Co | 2,676,143 | $9.21M | 0.00% | +463,047+20.9% | Added |
| Morgan Stanley | 2,621,574 | $9.02M | 0.00% | +1,760,173+204.3% | Added |
| Prudential Financial Inc | 2,587,076 | $8.90M | 0.01% | −94,880−3.5% | Reduced |
| Invesco Ltd. | 2,579,006 | $8.87M | 0.00% | +2,138,491+485.5% | Added |
| Bank of New York Mellon Corp | 2,115,948 | $7.28M | 0.00% | −4,996−0.2% | Reduced |
| Bank of America Corp | 1,794,830 | $6.17M | 0.00% | +1,175,492+189.8% | Added |
| Millennium Management LLC | 1,765,569 | $6.07M | 0.01% | +1,285,809+268.0% | Added |
| Rafferty Asset Management, LLC | 1,639,109 | $5.64M | 0.03% | +752,379+84.8% | Added |
| Nordea Investment Management AB | 1,329,997 | $4.71M | 0.01% | +9,908+0.8% | Added |
| Phoenix Holdings Ltd. | 1,328,562 | $4.57M | 0.08% | +1,328,562 | New |
| Susquehanna International Group, LLP | 1,214,277 | $4.18M | 0.01% | −2,759,565−69.4% | Reduced |
| Swiss National Bank | 1,047,200 | $3.60M | 0.00% | +72,900+7.5% | Added |
| UBS Group AG | 879,386 | $3.03M | 0.00% | +157,935+21.9% | Added |
| Hennion & Walsh Asset Management, Inc. | 801,974 | $2.76M | 0.15% | −40,352−4.8% | Reduced |
| AWM Investment Company, Inc. | 800,000 | $2.75M | 0.35% | 00.0% | Unchanged |
| Jupiter Asset Management Ltd | 788,416 | $2.70M | 0.03% | 00.0% | Unchanged |
| Alps Advisors Inc | 700,368 | $2.41M | 0.03% | −88,162−11.2% | Reduced |
| Weiss Multi-Strategy Advisers LLC | 650,000 | $2.24M | 0.05% | +650,000 | New |
| ExodusPoint Capital Management, LP | 620,216 | $2.13M | 0.03% | −161,929−20.7% | Reduced |
| Alliancebernstein L.P. | 599,400 | $2.06M | 0.00% | +1,500+0.3% | Added |
| AQR Capital Management LLC | 594,979 | $2.05M | 0.00% | +440,720+285.7% | Added |
| Landscape Capital Management, L.L.C. | 591,637 | $2.04M | 0.26% | +523,614+769.8% | Added |
| Point72 Asset Management, L.P. | 589,100 | $2.03M | 0.01% | −6,065,023−91.1% | Reduced |
| Rhumbline Advisers | 552,789 | $1.90M | 0.00% | −63,092−10.2% | Reduced |
| California State Teachers Retirement System | 546,710 | $1.88M | 0.00% | −45,683−7.7% | Reduced |
| Jane Street Group, LLC | 539,333 | $1.85M | 0.00% | −802,895−59.8% | Reduced |
| State of Wisconsin Investment Board | 535,300 | $1.84M | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 504,242 | $1.73M | 0.08% | +446,844+778.5% | Added |
| Wells Fargo & Company | 470,228 | $1.62M | 0.00% | −215,432−31.4% | Reduced |
| UBS Asset Management Americas Inc | 464,585 | $1.60M | 0.00% | +4,366+0.9% | Added |
| AXA S.A. | 436,100 | $1.50M | 0.00% | +407,100+1,403.8% | Added |
| Trellus Management Company, LLC | 422,881 | $1.46M | 1.81% | +422,881 | New |
| Credit Suisse AG | 420,432 | $1.45M | 0.00% | −38,846−8.5% | Reduced |
| Renaissance Technologies LLC | 410,043 | $1.41M | 0.00% | +410,043 | New |
| Commonwealth Equity Services, LLC | 402,730 | $1.39M | 0.00% | −1,085−0.3% | Reduced |
| State Board of Administration of Florida Retirement System | 366,480 | $1.26M | 0.00% | +63,683+21.0% | Added |
| Principal Financial Group Inc | 356,040 | $1.23M | 0.00% | −132,035−27.1% | Reduced |
| Legal & General Group Plc | 350,255 | $1.21M | 0.00% | +6,716+2.0% | Added |
| Two Sigma Advisers, LP | 342,200 | $1.18M | 0.00% | +60,900+21.6% | Added |
| First Trust Advisors LP | 333,867 | $1.15M | 0.00% | −160,231−32.4% | Reduced |
| Allspring Global Investments Holdings, LLC | 328,511 | $1.13M | 0.00% | −121,762−27.0% | Reduced |
| FMR LLC | 297,600 | $1.02M | 0.00% | +297,599+29,759,900.0% | Added |
| Citadel Advisors LLC | 296,618 | $1.02M | 0.00% | −531,447−64.2% | Reduced |
| Citigroup Inc | 279,947 | $963.0K | 0.00% | −465,786−62.5% | Reduced |
| Deutsche Bank AG | 274,542 | $944.0K | 0.00% | −50,553−15.6% | Reduced |
| Price T Rowe Associates Inc | 272,505 | $937.0K | 0.00% | −12,169−4.3% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 262,841 | $904.0K | 0.00% | −5,148−1.9% | Reduced |
| New York State Common Retirement Fund | 261,700 | $900.0K | 0.00% | −3,846−1.4% | Reduced |
| Victory Capital Management Inc | 325,794 | $880.0K | 0.00% | −50,155−13.3% | Reduced |
| Zebra Capital Management LLC | 250,259 | $861.0K | 1.98% | −101,486−28.9% | Reduced |
| Gabelli Funds LLC | 221,000 | $760.0K | 0.00% | 00.0% | Unchanged |
| Teton Advisors, Inc. | 220,000 | $757.0K | 0.13% | 00.0% | Unchanged |
| Royal Bank of Canada | 214,989 | $740.0K | 0.00% | −76,816−26.3% | Reduced |
| ETF Managers Group, LLC | 206,672 | $732.0K | 0.01% | −93,069−31.0% | Reduced |
| MetLife Investment Management | 206,296 | $709.7K | 0.00% | +85,349+70.6% | Added |
| X-Square Capital, LLC | 205,396 | $707.0K | 0.37% | −45,569−18.2% | Reduced |
| Gamco Investors, Inc. Et Al | 200,000 | $688.0K | 0.01% | 00.0% | Unchanged |
| American International Group, Inc. | 198,386 | $682.0K | 0.00% | −13,964−6.6% | Reduced |
| Mark Asset Management LP | 190,694 | $656.0K | 0.12% | +190,694 | New |
| Parametric Portfolio Associates LLC | 175,466 | $604.0K | 0.00% | −60,865−25.8% | Reduced |
| Manufacturers Life Insurance Company, The | 172,454 | $593.2K | 0.00% | −36,017−17.3% | Reduced |
| Capital Advisors Inc | 164,625 | $566.0K | 0.02% | 00.0% | Unchanged |
| Vident Investment Advisory, LLC | 161,037 | $554.0K | 0.01% | +161,037 | New |
| Voya Investment Management LLC | 160,421 | $552.0K | 0.00% | +3,660+2.3% | Added |
| Advisor Group Holdings, Inc. | 165,601 | $487.0K | 0.00% | −386,812−70.0% | Reduced |
| Ameriprise Financial Inc | 134,868 | $464.0K | 0.00% | −6,171−4.4% | Reduced |
| Simplex Trading, LLC | 126,869 | $436.0K | 0.01% | −69,983−35.6% | Reduced |
| Arizona State Retirement System | 119,715 | $412.0K | 0.00% | +549+0.5% | Added |
| Susquehanna International Group Ltd. | 117,816 | $409.0K | 0.14% | +117,816 | New |
| IndexIQ Advisors LLC | 109,868 | $378.0K | 0.01% | +109,868 | New |
| Virginia Retirement Systems Et Al | 108,100 | $372.0K | 0.00% | −10,700−9.0% | Reduced |
| Matrix Private Capital Group LLC | 106,086 | $365.0K | 0.18% | 00.0% | Unchanged |
| Group One Trading, L.P. | 105,587 | $363.0K | 0.01% | −254,524−70.7% | Reduced |
| Handelsbanken Fonder AB | 101,621 | $350.0K | 0.00% | −22,000−17.8% | Reduced |
| Sequoia Financial Advisors, LLC | 94,071 | $324.0K | 0.01% | +10,000+11.9% | Added |
| Teacher Retirement System of Texas | 90,494 | $311.0K | 0.00% | +3,972+4.6% | Added |
| Janus Henderson Group PLC | 88,092 | $302.0K | 0.00% | +150.0% | Added |
| Creative Planning | 85,247 | $293.0K | 0.00% | −298−0.3% | Reduced |
| Hollencrest Capital Management | 83,980 | $289.0K | 0.03% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 81,338 | $280.0K | 0.01% | +53,299+190.1% | Added |
| AE Wealth Management LLC | 79,313 | $273.0K | 0.00% | −22,760−22.3% | Reduced |
| ProShare Advisors LLC | 74,923 | $257.0K | 0.00% | −12,374−14.2% | Reduced |
| Fairfield, Bush & Co. | 73,650 | $253.0K | 0.13% | −6,000−7.5% | Reduced |
| Engineers Gate Manager LP | 71,689 | $247.0K | 0.01% | +32,294+82.0% | Added |
| BNP Paribas Arbitrage, SA | 70,210 | $241.5K | 0.00% | −95,718−57.7% | Reduced |
| BDO Wealth Advisors, LLC | 70,000 | $241.0K | 0.03% | +3,000+4.5% | Added |
| Barclays PLC | 66,910 | $230.0K | 0.00% | −438,103−86.8% | Reduced |
| Norris Perne & French LLP | 67,000 | $230.0K | 0.02% | 00.0% | Unchanged |