Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Opko Health, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 218
- −7 vs. Q3 2023
- Shares held
- 169.9M
- +2.69M (+1.6%) vs. Q3 2023
- Total value
- $256.6M
- −$11.0M (−4.1%) vs. Q3 2023
- New holders
- 25
- 53 more added
- Sold out
- 32
- 65 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 39,751,293 | $60.0M | 0.00% | +428,520+1.1% | Added |
| BlackRock Inc. | 36,965,429 | $55.8M | 0.00% | +2,206,364+6.3% | Added |
| Geode Capital Management, LLC | 9,719,368 | $14.7M | 0.00% | +589,076+6.5% | Added |
| State Street Corp | 9,306,684 | $14.1M | 0.00% | −31,744−0.3% | Reduced |
| D. E. Shaw & Co., Inc. | 5,842,537 | $8.82M | 0.01% | −320,902−5.2% | Reduced |
| Charles Schwab Investment Management Inc | 5,733,700 | $8.66M | 0.00% | +183,754+3.3% | Added |
| Invesco Ltd. | 5,494,276 | $8.30M | 0.00% | +330,096+6.4% | Added |
| Northern Trust Corp | 5,034,255 | $7.60M | 0.00% | +515,838+11.4% | Added |
| Dimensional Fund Advisors LP | 3,449,062 | $5.21M | 0.00% | −864,430−20.0% | Reduced |
| Goldman Sachs Group Inc | 2,909,499 | $4.39M | 0.00% | +736,158+33.9% | Added |
| Norges Bank | 2,703,082 | $4.08M | 0.00% | −209,790−7.2% | Reduced |
| JPMorgan Chase & Co | 1,944,337 | $2.94M | 0.00% | +51,999+2.7% | Added |
| Morgan Stanley | 1,870,343 | $2.82M | 0.00% | +431,243+30.0% | Added |
| Voya Investment Management LLC | 1,741,571 | $2.63M | 0.00% | −62,046−3.4% | Reduced |
| Portolan Capital Management, LLC | 1,661,766 | $2.51M | 0.22% | +1,661,766 | New |
| Bank of New York Mellon Corp | 1,613,399 | $2.44M | 0.00% | +35,570+2.3% | Added |
| Citigroup Inc | 1,549,582 | $2.34M | 0.00% | +65,824+4.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 1,538,716 | $2.32M | 0.01% | +118,759+8.4% | Added |
| UBS Group AG | 1,413,300 | $2.13M | 0.00% | +399,290+39.4% | Added |
| Nuveen Asset Management, LLC | 1,147,369 | $1.73M | 0.00% | −1,517,045−56.9% | Reduced |
| Two Sigma Advisers, LP | 1,136,897 | $1.72M | 0.00% | −176,200−13.4% | Reduced |
| AWM Investment Company, Inc. | 1,100,000 | $1.66M | 0.22% | +100,000+10.0% | Added |
| Intrinsic Edge Capital Management LLC | 1,000,000 | $1.51M | 0.16% | +100,000+11.1% | Added |
| Two Sigma Investments, LP | 968,815 | $1.46M | 0.00% | −471,367−32.7% | Reduced |
| Deutsche Bank AG | 951,120 | $1.44M | 0.00% | +722,249+315.6% | Added |
| Credit Suisse AG | 896,018 | $1.35M | 0.00% | +260,379+41.0% | Added |
| Swiss National Bank | 837,855 | $1.27M | 0.00% | −96,200−10.3% | Reduced |
| Barclays PLC | 768,078 | $1.16M | 0.00% | +579,657+307.6% | Added |
| Jupiter Asset Management Ltd | 765,198 | $1.16M | 0.01% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 764,209 | $1.15M | 0.00% | +263,389+52.6% | Added |
| Weiss Multi-Strategy Advisers LLC | 700,000 | $1.06M | 0.03% | +700,000 | New |
| Hennion & Walsh Asset Management, Inc. | 696,495 | $1.05M | 0.06% | +28,975+4.3% | Added |
| Rhumbline Advisers | 650,017 | $981.5K | 0.00% | +1,132+0.2% | Added |
| Assenagon Asset Management S.A. | 605,239 | $959.7K | 0.00% | −254,100−29.6% | Reduced |
| Millennium Management LLC | 596,444 | $900.6K | 0.00% | −516,842−46.4% | Reduced |
| Alliancebernstein L.P. | 570,109 | $860.9K | 0.00% | −20,130−3.4% | Reduced |
| Alps Advisors Inc | 536,481 | $810.1K | 0.01% | +536,481 | New |
| Susquehanna International Group, LLP | 496,397 | $749.6K | 0.00% | +342,832+223.2% | Added |
| Marshall Wace, LLP | 465,493 | $702.9K | 0.00% | −99,040−17.5% | Reduced |
| California State Teachers Retirement System | 444,922 | $671.8K | 0.00% | −19,639−4.2% | Reduced |
| Price T Rowe Associates Inc | 428,310 | $647.0K | 0.00% | +29,117+7.3% | Added |
| Legal & General Group Plc | 418,602 | $632.1K | 0.00% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 412,926 | $624.0K | 0.00% | −1,943−0.5% | Reduced |
| Citadel Advisors LLC | 408,551 | $616.9K | 0.00% | +198,960+94.9% | Added |
| Bank of America Corp | 408,055 | $616.2K | 0.00% | +117,161+40.3% | Added |
| UBS Asset Management Americas Inc | 401,189 | $605.8K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 358,144 | $540.8K | 0.00% | +216,369+152.6% | Added |
| HRT Financial LP | 343,605 | $518.0K | 0.00% | +89,275+35.1% | Added |
| AQR Capital Management LLC | 326,655 | $493.2K | 0.00% | +151,025+86.0% | Added |
| Engineers Gate Manager LP | 320,419 | $483.8K | 0.01% | −27,107−7.8% | Reduced |
| Group One Trading, L.P. | 308,615 | $466.0K | 0.01% | +308,615 | New |
| First Trust Advisors LP | 305,731 | $461.7K | 0.00% | +305,731 | New |
| Royal Bank of Canada | 304,411 | $460.0K | 0.00% | +50,248+19.8% | Added |
| American Century Companies Inc | 276,664 | $417.8K | 0.00% | −1,008−0.4% | Reduced |
| BNP Paribas Arbitrage, SA | 271,872 | $410.5K | 0.00% | +211,429+349.8% | Added |
| ExodusPoint Capital Management, LP | 265,830 | $401.0K | 0.00% | +253,741+2,098.9% | Added |
| Tudor Investment Corp Et Al | 244,821 | $369.7K | 0.01% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 244,294 | $369.0K | 0.00% | +39,459+19.3% | Added |
| Graham Capital Management, L.P. | 235,604 | $355.8K | 0.01% | +47,543+25.3% | Added |
| Manufacturers Life Insurance Company, The | 234,887 | $354.7K | 0.00% | −6,330−2.6% | Reduced |
| MetLife Investment Management | 211,348 | $319.1K | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 208,449 | $313.7K | 0.00% | −345−0.2% | Reduced |
| American International Group, Inc. | 200,496 | $302.7K | 0.00% | −810−0.4% | Reduced |
| Franklin Resources Inc | 193,867 | $292.7K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 185,805 | $280.6K | 0.00% | +14,682+8.6% | Added |
| Gamco Investors, Inc. Et Al | 185,000 | $279.4K | 0.00% | −15,000−7.5% | Reduced |
| Gabelli Funds LLC | 181,000 | $273.3K | 0.00% | 00.0% | Unchanged |
| X-Square Capital, LLC | 177,900 | $269.0K | 0.15% | −2,170−1.2% | Reduced |
| State Board of Administration of Florida Retirement System | 176,260 | $266.2K | 0.00% | 00.0% | Unchanged |
| Teton Advisors, Inc. | 170,000 | $256.7K | 0.08% | −8,000−4.5% | Reduced |
| POM Investment Strategies, LLC | 158,053 | $238.7K | 0.22% | +158,053 | New |
| Simplex Trading, LLC | 148,360 | $224.0K | 0.01% | +148,360 | New |
| Parallax Volatility Advisers, L.P. | 134,280 | $202.8K | 0.01% | +134,280 | New |
| Van Eck Associates Corp | 132,935 | $201.0K | 0.00% | −17,836−11.8% | Reduced |
| Wilbanks Smith & Thomas Asset Management LLC | 131,380 | $198.4K | 0.01% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 127,900 | $193.1K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 118,857 | $179.5K | 0.00% | −2,142−1.8% | Reduced |
| Csenge Advisory Group | 117,000 | $176.7K | 0.01% | 00.0% | Unchanged |
| Highline Wealth Partners LLC | 116,680 | $176.2K | 0.09% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 116,239 | $176.0K | 0.00% | +290+0.3% | Added |
| Ameriprise Financial Inc | 110,691 | $167.1K | 0.00% | −138,118−55.5% | Reduced |
| Blair William & Co | 109,786 | $165.8K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 106,676 | $161.1K | 0.00% | −22,177−17.2% | Reduced |
| Prudential Financial Inc | 104,996 | $158.5K | 0.00% | −235−0.2% | Reduced |
| Intrepid Capital Management Inc | 100,000 | $151.0K | 0.10% | 00.0% | Unchanged |
| Verition Fund Management LLC | 99,798 | $150.7K | 0.00% | −49,753−33.3% | Reduced |
| State of Wyoming | 82,890 | $125.2K | 0.02% | −4,627−5.3% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 80,348 | $121.3K | 0.00% | +80,348 | New |
| RPg Family Wealth Advisory, LLC | 80,330 | $121.3K | 0.04% | 00.0% | Unchanged |
| Hollencrest Capital Management | 78,980 | $119.3K | 0.01% | −5,000−6.0% | Reduced |
| Handelsbanken Fonder AB | 76,721 | $116.0K | 0.00% | −9,400−10.9% | Reduced |
| Qube Research & Technologies Ltd | 74,259 | $112.1K | 0.00% | −871−1.2% | Reduced |
| RSM US Wealth Management LLC | 70,000 | $105.7K | 0.00% | +70,000 | New |
| ProShare Advisors LLC | 66,766 | $100.8K | 0.00% | +14,365+27.4% | Added |
| Pictet Asset Management Holding SA | 65,495 | $98.9K | 0.00% | 00.0% | Unchanged |
| 360 Financial, Inc. | 62,500 | $94.4K | 0.04% | +7,340+13.3% | Added |
| Public Employees Retirement Association of Colorado | 61,502 | $93.0K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 55,899 | $84.4K | 0.00% | +10,023+21.8% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $83.3K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 54,068 | $81.0K | 0.00% | 00.0% | Unchanged |