Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q2 2022
Institutional positions in Opko Health, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 231
- +8 vs. Q1 2022
- Shares held
- 189.7M
- −4.80M (−2.5%) vs. Q1 2022
- Total value
- $479.9M
- −$189.5M (−28.3%) vs. Q1 2022
- New holders
- 32
- 63 more added
- Sold out
- 24
- 73 more reduced
6 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 42,581,244 | $107.7M | 0.00% | +6,509,113+18.0% | Added |
| BlackRock Inc. | 35,010,347 | $88.6M | 0.00% | +1,139,979+3.4% | Added |
| State Street Corp | 9,866,509 | $25.0M | 0.00% | −17,822,322−64.4% | Reduced |
| Dimensional Fund Advisors LP | 9,078,680 | $23.0M | 0.01% | +1,894,266+26.4% | Added |
| Geode Capital Management, LLC | 7,628,732 | $19.3M | 0.00% | −138,759−1.8% | Reduced |
| Millennium Management LLC | 7,390,435 | $18.7M | 0.02% | +5,624,866+318.6% | Added |
| Oracle Investment Management Inc | 7,252,756 | $18.3M | 5.63% | −1,733,000−19.3% | Reduced |
| D. E. Shaw & Co., Inc. | 6,366,216 | $16.1M | 0.03% | +990,990+18.4% | Added |
| Northern Trust Corp | 5,067,897 | $12.8M | 0.00% | −667,029−11.6% | Reduced |
| Renaissance Technologies LLC | 3,890,172 | $9.84M | 0.01% | +3,480,129+848.7% | Added |
| Charles Schwab Investment Management Inc | 3,392,673 | $8.58M | 0.00% | −478,230−12.4% | Reduced |
| Norges Bank | 3,233,385 | $8.18M | 0.00% | −599,556−15.6% | Reduced |
| Nuveen Asset Management, LLC | 2,685,206 | $6.79M | 0.00% | −808,276−23.1% | Reduced |
| Invesco Ltd. | 2,665,776 | $6.74M | 0.00% | +86,770+3.4% | Added |
| Goldman Sachs Group Inc | 2,621,483 | $6.63M | 0.00% | −379,928−12.7% | Reduced |
| Citigroup Inc | 2,167,613 | $5.48M | 0.01% | +1,887,666+674.3% | Added |
| JPMorgan Chase & Co | 2,029,463 | $5.13M | 0.00% | −646,680−24.2% | Reduced |
| Bank of New York Mellon Corp | 1,923,992 | $4.87M | 0.00% | −191,956−9.1% | Reduced |
| Two Sigma Investments, LP | 1,695,940 | $4.29M | 0.01% | +1,695,940 | New |
| Deutsche Bank AG | 1,528,223 | $3.87M | 0.00% | +1,253,681+456.6% | Added |
| Prudential Financial Inc | 1,395,476 | $3.53M | 0.01% | −1,191,600−46.1% | Reduced |
| Morgan Stanley | 1,362,544 | $3.45M | 0.00% | −1,259,030−48.0% | Reduced |
| Nordea Investment Management AB | 1,334,535 | $3.31M | 0.00% | +4,538+0.3% | Added |
| Susquehanna International Group, LLP | 1,298,511 | $3.29M | 0.01% | +84,234+6.9% | Added |
| Phoenix Holdings Ltd. | 1,224,062 | $3.10M | 0.06% | −104,500−7.9% | Reduced |
| Swiss National Bank | 1,047,200 | $2.65M | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 1,046,418 | $2.65M | 0.00% | +749,800+252.8% | Added |
| Two Sigma Advisers, LP | 846,797 | $2.14M | 0.01% | +504,597+147.5% | Added |
| Cubist Systematic Strategies, LLC | 832,978 | $2.11M | 0.02% | +787,939+1,749.5% | Added |
| AWM Investment Company, Inc. | 800,000 | $2.02M | 0.32% | 00.0% | Unchanged |
| Jupiter Asset Management Ltd | 765,198 | $1.93M | 0.03% | −23,218−2.9% | Reduced |
| Jump Financial, LLC | 660,608 | $1.67M | 0.07% | +645,208+4,189.7% | Added |
| Rhumbline Advisers | 606,185 | $1.53M | 0.00% | +53,396+9.7% | Added |
| Alliancebernstein L.P. | 606,000 | $1.53M | 0.00% | +6,600+1.1% | Added |
| Jane Street Group, LLC | 597,602 | $1.51M | 0.00% | +58,269+10.8% | Added |
| Trellus Management Company, LLC | 590,000 | $1.49M | 2.11% | +167,119+39.5% | Added |
| California State Teachers Retirement System | 549,460 | $1.39M | 0.00% | +2,750+0.5% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 524,622 | $1.33M | 0.01% | +524,622 | New |
| State of Wisconsin Investment Board | 474,637 | $1.20M | 0.00% | −60,663−11.3% | Reduced |
| UBS Asset Management Americas Inc | 450,196 | $1.14M | 0.00% | −14,389−3.1% | Reduced |
| Commonwealth Equity Services, LLC | 405,731 | $1.03M | 0.00% | +3,001+0.7% | Added |
| Credit Suisse AG | 404,733 | $1.02M | 0.00% | −15,699−3.7% | Reduced |
| Alps Advisors Inc | 404,542 | $1.02M | 0.01% | −295,826−42.2% | Reduced |
| Group One Trading, L.P. | 379,983 | $961.0K | 0.03% | +274,396+259.9% | Added |
| Legal & General Group Plc | 347,200 | $878.0K | 0.00% | −3,055−0.9% | Reduced |
| State Board of Administration of Florida Retirement System | 346,661 | $877.0K | 0.00% | −19,819−5.4% | Reduced |
| Victory Capital Management Inc | 337,558 | $854.0K | 0.00% | +11,764+3.6% | Added |
| Marshall Wace, LLP | 335,123 | $848.0K | 0.00% | +335,123 | New |
| Principal Financial Group Inc | 325,485 | $823.0K | 0.00% | −30,555−8.6% | Reduced |
| Zebra Capital Management LLC | 285,778 | $723.0K | 2.12% | +35,519+14.2% | Added |
| Price T Rowe Associates Inc | 275,601 | $697.0K | 0.00% | +3,096+1.1% | Added |
| Weiss Multi-Strategy Advisers LLC | 275,000 | $696.0K | 0.02% | −375,000−57.7% | Reduced |
| HRT Financial LP | 274,961 | $695.0K | 0.01% | +274,961 | New |
| Schonfeld Strategic Advisors LLC | 274,195 | $694.0K | 0.01% | +233,595+575.4% | Added |
| New York State Common Retirement Fund | 261,700 | $662.0K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 261,441 | $661.0K | 0.00% | −1,400−0.5% | Reduced |
| Pinz Capital Management, LP | 252,200 | $638.0K | 0.44% | +252,200 | New |
| AXA S.A. | 248,025 | $627.5K | 0.00% | −188,075−43.1% | Reduced |
| ExodusPoint Capital Management, LP | 240,400 | $608.0K | 0.01% | −379,816−61.2% | Reduced |
| Engineers Gate Manager LP | 224,624 | $568.0K | 0.02% | +152,935+213.3% | Added |
| Gabelli Funds LLC | 221,000 | $559.0K | 0.00% | 00.0% | Unchanged |
| ETF Managers Group, LLC | 215,295 | $558.0K | 0.02% | +8,623+4.2% | Added |
| Teton Advisors, Inc. | 220,000 | $557.0K | 0.12% | 00.0% | Unchanged |
| MetLife Investment Management | 214,381 | $542.4K | 0.00% | +8,085+3.9% | Added |
| X-Square Capital, LLC | 205,396 | $520.0K | 0.31% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 200,000 | $506.0K | 0.01% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 192,352 | $486.0K | 0.02% | −311,890−61.9% | Reduced |
| Quantbot Technologies LP | 191,968 | $485.0K | 0.04% | +191,968 | New |
| Royal Bank of Canada | 190,216 | $482.0K | 0.00% | −24,773−11.5% | Reduced |
| American International Group, Inc. | 188,968 | $478.0K | 0.00% | −9,418−4.7% | Reduced |
| Mark Asset Management LP | 186,441 | $472.0K | 0.11% | −4,253−2.2% | Reduced |
| Manufacturers Life Insurance Company, The | 172,619 | $436.7K | 0.00% | +165+0.1% | Added |
| UBS Group AG | 171,489 | $434.0K | 0.00% | −707,897−80.5% | Reduced |
| AQR Capital Management LLC | 168,853 | $427.0K | 0.00% | −426,126−71.6% | Reduced |
| First Trust Advisors LP | 168,707 | $427.0K | 0.00% | −165,160−49.5% | Reduced |
| Vident Investment Advisory, LLC | 168,562 | $426.0K | 0.01% | +7,525+4.7% | Added |
| Hennion & Walsh Asset Management, Inc. | 166,703 | $422.0K | 0.03% | −635,271−79.2% | Reduced |
| Van Eck Associates Corp | 159,679 | $404.0K | 0.00% | +159,679 | New |
| SG Americas Securities, LLC | 158,238 | $400.0K | 0.01% | +96,929+158.1% | Added |
| Voya Investment Management LLC | 156,761 | $397.0K | 0.00% | −3,660−2.3% | Reduced |
| Advisor Group Holdings, Inc. | 154,240 | $394.0K | 0.00% | −11,361−6.9% | Reduced |
| Bank of America Corp | 150,927 | $381.0K | 0.00% | −1,643,903−91.6% | Reduced |
| Squarepoint Ops LLC | 143,711 | $364.0K | 0.00% | +105,786+278.9% | Added |
| Wilbanks Smith & Thomas Asset Management LLC | 135,976 | $344.0K | 0.01% | +135,976 | New |
| New York Life Investment Management LLC | 135,564 | $343.0K | 0.00% | +135,564 | New |
| Ameriprise Financial Inc | 131,239 | $332.0K | 0.00% | −3,629−2.7% | Reduced |
| Arizona State Retirement System | 120,019 | $304.0K | 0.00% | +304+0.3% | Added |
| Csenge Advisory Group | 117,000 | $296.0K | 0.02% | +117,000 | New |
| BNP Paribas Arbitrage, SA | 106,968 | $270.6K | 0.00% | +36,758+52.4% | Added |
| Matrix Private Capital Group LLC | 106,086 | $268.0K | 0.15% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 101,621 | $257.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 97,796 | $247.0K | 0.01% | −29,073−22.9% | Reduced |
| Janus Henderson Group PLC | 89,745 | $226.0K | 0.00% | +1,653+1.9% | Added |
| Creative Planning | 89,210 | $226.0K | 0.00% | +3,963+4.6% | Added |
| Hollencrest Capital Management | 83,980 | $212.0K | 0.02% | 00.0% | Unchanged |
| Wells Fargo & Company | 83,105 | $209.0K | 0.00% | −387,123−82.3% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 81,997 | $207.0K | 0.03% | +81,997 | New |
| AE Wealth Management LLC | 79,313 | $201.0K | 0.00% | 00.0% | Unchanged |
| Occudo Quantitative Strategies LP | 75,403 | $191.0K | 0.02% | +44,460+143.7% | Added |
| Point72 Hong Kong Ltd | 72,494 | $183.0K | 0.01% | +61,016+531.6% | Added |