Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Opko Health, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 236
- +30 vs. Q3 2021
- Shares held
- 190.2M
- +6.95M (+3.8%) vs. Q3 2021
- Total value
- $914.8M
- +$246.0M (+36.8%) vs. Q3 2021
- New holders
- 53
- 58 more added
- Sold out
- 23
- 63 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 35,725,424 | $171.8M | 0.00% | +259,540+0.7% | Added |
| BlackRock Inc. | 34,390,912 | $165.4M | 0.00% | −434,768−1.2% | Reduced |
| State Street Corp | 17,674,743 | $85.0M | 0.00% | −5,699,872−24.4% | Reduced |
| Oracle Investment Management Inc | 12,219,073 | $58.8M | 8.63% | −600,000−4.7% | Reduced |
| Geode Capital Management, LLC | 7,730,412 | $37.2M | 0.00% | +1,6820.0% | Added |
| Point72 Asset Management, L.P. | 6,654,123 | $32.0M | 0.14% | +6,654,123 | New |
| Northern Trust Corp | 6,235,600 | $30.0M | 0.00% | −76,350−1.2% | Reduced |
| Norges Bank | 4,276,383 | $20.6M | 0.00% | +1,215,448+39.7% | Added |
| Dimensional Fund Advisors LP | 4,147,094 | $19.9M | 0.01% | −326,001−7.3% | Reduced |
| D. E. Shaw & Co., Inc. | 4,081,001 | $19.6M | 0.02% | +2,003,147+96.4% | Added |
| Susquehanna International Group, LLP | 3,973,842 | $19.1M | 0.03% | +966,579+32.1% | Added |
| Goldman Sachs Group Inc | 3,859,444 | $18.6M | 0.00% | +1,844,799+91.6% | Added |
| Charles Schwab Investment Management Inc | 3,574,865 | $17.2M | 0.01% | +24,106+0.7% | Added |
| Nuveen Asset Management, LLC | 3,492,210 | $16.8M | 0.00% | +656,465+23.1% | Added |
| Prudential Financial Inc | 2,681,956 | $12.9M | 0.02% | −1,099,863−29.1% | Reduced |
| JPMorgan Chase & Co | 2,213,096 | $10.6M | 0.00% | +936,522+73.4% | Added |
| Bank of New York Mellon Corp | 2,120,944 | $10.2M | 0.00% | +166,335+8.5% | Added |
| Nordea Investment Management AB | 1,320,089 | $6.53M | 0.01% | −8,753−0.7% | Reduced |
| Jane Street Group, LLC | 1,342,228 | $6.46M | 0.01% | +863,575+180.4% | Added |
| Swiss National Bank | 974,300 | $4.69M | 0.00% | +14,300+1.5% | Added |
| Rafferty Asset Management, LLC | 886,730 | $4.26M | 0.02% | +16,064+1.8% | Added |
| Morgan Stanley | 861,401 | $4.14M | 0.00% | −262,464−23.4% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 842,326 | $4.05M | 0.20% | −769,741−47.7% | Reduced |
| Citadel Advisors LLC | 828,065 | $3.98M | 0.00% | +616,393+291.2% | Added |
| AWM Investment Company, Inc. | 800,000 | $3.85M | 0.39% | 00.0% | Unchanged |
| Jupiter Asset Management Ltd | 788,416 | $3.82M | 0.04% | +224,398+39.8% | Added |
| Alps Advisors Inc | 788,530 | $3.79M | 0.04% | +788,530 | New |
| ExodusPoint Capital Management, LP | 782,145 | $3.76M | 0.05% | +345,531+79.1% | Added |
| Citigroup Inc | 745,733 | $3.59M | 0.00% | +132,243+21.6% | Added |
| UBS Group AG | 721,451 | $3.47M | 0.00% | −95,826−11.7% | Reduced |
| Wells Fargo & Company | 685,660 | $3.30M | 0.00% | −334,792−32.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 627,454 | $3.02M | 0.01% | −361,676−36.6% | Reduced |
| Bank of America Corp | 619,338 | $2.98M | 0.00% | +399,970+182.3% | Added |
| Rhumbline Advisers | 615,881 | $2.96M | 0.00% | −4,975−0.8% | Reduced |
| Alliancebernstein L.P. | 597,900 | $2.88M | 0.00% | −300,000−33.4% | Reduced |
| California State Teachers Retirement System | 592,393 | $2.85M | 0.00% | +19,485+3.4% | Added |
| Advisor Group Holdings, Inc. | 552,413 | $2.66M | 0.01% | +355,163+180.1% | Added |
| State of Wisconsin Investment Board | 535,300 | $2.58M | 0.00% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 508,967 | $2.45M | 0.01% | +508,967 | New |
| Barclays PLC | 505,013 | $2.43M | 0.00% | +286,073+130.7% | Added |
| First Trust Advisors LP | 494,098 | $2.38M | 0.00% | −480,834−49.3% | Reduced |
| Principal Financial Group Inc | 488,075 | $2.35M | 0.00% | −506,797−50.9% | Reduced |
| Millennium Management LLC | 479,760 | $2.31M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 460,219 | $2.21M | 0.00% | +29,127+6.8% | Added |
| Credit Suisse AG | 459,278 | $2.21M | 0.00% | +37,855+9.0% | Added |
| Allspring Global Investments Holdings, LLC | 450,273 | $2.17M | 0.00% | +450,273 | New |
| Invesco Ltd. | 440,515 | $2.12M | 0.00% | −2,199,365−83.3% | Reduced |
| Toronto Dominion Bank | 437,732 | $2.10M | 0.00% | +437,732 | New |
| Old Mission Capital LLC | 412,551 | $1.98M | 0.10% | +412,551 | New |
| Commonwealth Equity Services, LLC | 403,815 | $1.94M | 0.00% | −100.0% | Reduced |
| Victory Capital Management Inc | 375,949 | $1.81M | 0.00% | −323,907−46.3% | Reduced |
| Verition Fund Management LLC | 375,702 | $1.81M | 0.02% | +375,702 | New |
| Group One Trading, L.P. | 360,111 | $1.73M | 0.03% | −14,059−3.8% | Reduced |
| Susquehanna Fundamental Investments, LLC | 356,280 | $1.71M | 0.04% | +177,840+99.7% | Added |
| Zebra Capital Management LLC | 351,745 | $1.69M | 2.71% | −117,338−25.0% | Reduced |
| Legal & General Group Plc | 343,539 | $1.65M | 0.00% | −3,833−1.1% | Reduced |
| Deutsche Bank AG | 325,095 | $1.56M | 0.00% | −6,874−2.1% | Reduced |
| HRT Financial LP | 313,544 | $1.51M | 0.01% | +313,544 | New |
| Cubist Systematic Strategies, LLC | 309,357 | $1.49M | 0.01% | +214,532+226.2% | Added |
| State Board of Administration of Florida Retirement System | 302,797 | $1.46M | 0.00% | +126,777+72.0% | Added |
| ETF Managers Group, LLC | 299,741 | $1.45M | 0.03% | +51,025+20.5% | Added |
| Intrinsic Edge Capital Management LLC | 300,000 | $1.44M | 0.11% | +300,000 | New |
| Royal Bank of Canada | 291,805 | $1.40M | 0.00% | +147,106+101.7% | Added |
| Price T Rowe Associates Inc | 284,674 | $1.37M | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 281,300 | $1.35M | 0.00% | +261,000+1,285.7% | Added |
| Cambridge Investment Research Advisors, Inc. | 267,989 | $1.29M | 0.01% | −19,085−6.6% | Reduced |
| New York State Common Retirement Fund | 265,546 | $1.28M | 0.00% | 00.0% | Unchanged |
| X-Square Capital, LLC | 250,965 | $1.21M | 0.61% | +19,500+8.4% | Added |
| Parametric Portfolio Associates LLC | 236,331 | $1.14M | 0.00% | −37,190−13.6% | Reduced |
| Gabelli Funds LLC | 221,000 | $1.06M | 0.01% | 00.0% | Unchanged |
| Teton Advisors, Inc. | 220,000 | $1.06M | 0.15% | 00.0% | Unchanged |
| American International Group, Inc. | 212,350 | $1.02M | 0.01% | −6,353−2.9% | Reduced |
| Squarepoint Ops LLC | 210,703 | $1.01M | 0.00% | +210,703 | New |
| Manufacturers Life Insurance Company, The | 208,471 | $1.00M | 0.00% | −4,107−1.9% | Reduced |
| Gamco Investors, Inc. Et Al | 200,000 | $962.0K | 0.01% | 00.0% | Unchanged |
| Simplex Trading, LLC | 196,852 | $946.0K | 0.03% | +196,852 | New |
| BNP Paribas Arbitrage, SA | 165,928 | $798.1K | 0.00% | +26,707+19.2% | Added |
| Capital Advisors Inc | 164,625 | $792.0K | 0.02% | 00.0% | Unchanged |
| Voya Investment Management LLC | 156,761 | $754.0K | 0.00% | −1,726−1.1% | Reduced |
| AQR Capital Management LLC | 154,259 | $742.0K | 0.00% | −146,248−48.7% | Reduced |
| Ameriprise Financial Inc | 141,039 | $679.0K | 0.00% | −4,190−2.9% | Reduced |
| Wolverine Asset Management LLC | 138,500 | $666.0K | 0.01% | +138,500 | New |
| SG Americas Securities, LLC | 135,741 | $653.0K | 0.00% | −124,006−47.7% | Reduced |
| Handelsbanken Fonder AB | 123,621 | $595.0K | 0.00% | +44,200+55.7% | Added |
| MetLife Investment Management | 120,947 | $581.8K | 0.00% | −19,559−13.9% | Reduced |
| Arizona State Retirement System | 119,166 | $573.0K | 0.00% | +512+0.4% | Added |
| Virginia Retirement Systems Et Al | 118,800 | $571.0K | 0.01% | −25,900−17.9% | Reduced |
| Matrix Private Capital Group LLC | 106,086 | $510.0K | 0.24% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 105,379 | $506.9K | 0.01% | −2,402−2.2% | Reduced |
| AE Wealth Management LLC | 102,073 | $491.0K | 0.00% | −20,275−16.6% | Reduced |
| Jump Financial, LLC | 93,080 | $447.0K | 0.03% | −274,235−74.7% | Reduced |
| Janus Henderson Group PLC | 88,077 | $424.0K | 0.00% | +44,259+101.0% | Added |
| ProShare Advisors LLC | 87,297 | $420.0K | 0.00% | +36,089+70.5% | Added |
| Teacher Retirement System of Texas | 86,522 | $416.0K | 0.00% | +16,288+23.2% | Added |
| Creative Planning | 85,545 | $411.0K | 0.00% | −122−0.1% | Reduced |
| Sax Wealth Advisors, LLC | 84,110 | $405.0K | 0.08% | −25,491−23.3% | Reduced |
| Hollencrest Capital Management | 83,980 | $404.0K | 0.03% | +50,000+147.1% | Added |
| Sequoia Financial Advisors, LLC | 84,071 | $404.0K | 0.01% | +84,071 | New |
| Fairfield, Bush & Co. | 79,650 | $383.0K | 0.18% | +15,000+23.2% | Added |
| Bank of Nova Scotia | 77,477 | $376.0K | 0.00% | +77,477 | New |