Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
Holders of 5% or more of OPK
Holders whose latest Schedule 13D or 13G filing reports 5% or more of Opko Health, Inc., largest stake first. The change is against the holder's previous filing.
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Frost Phillip MD Et Al | 13D/A | 32.80%252.9M shares | +1.10 ppfrom 31.70% | Apr 3, 20252 filings | Oct 1, 2025 | SEC |
| Rubric Capital Management LP | 13G/A | 6.03%47.8M shares | – | Jul 9, 20251 filing | Jul 9, 2025 | SEC |
Stakes are as of each holder's latest filing. Holders whose last filing was in the old format (before December 18, 2024) have no stake on record and are not listed, and after an acquisition or delisting holders usually stop filing.
13D and 13G filings
4 Schedule 13D and 13G filings on Opko Health, Inc., newest first, including old-format filings without a stake.
| Filed (ET) | Filer | Form | Stake | Change | Event date | Filing |
|---|---|---|---|---|---|---|
| Oct 1, 20254:46 PM ET | Frost Phillip MD Et Aland 2 others | 13D/A | 32.80%252.9M shares | +1.10 ppfrom 31.70% | Sep 30, 2025 | SEC |
| Jul 9, 20254:10 PM ET | Rubric Capital Management LPand 1 other | 13G/A | 6.03%47.8M shares | – | Jun 30, 2025 | SEC |
| Apr 3, 20255:22 PM ET | Frost Phillip MD Et Aland 2 others | 13D/A | 31.70%252.4M shares | – | Apr 2, 2025 | SEC |
| Apr 3, 20255:21 PM ET | Hsiao Jane PH Dand 1 other | 13D/A | 4.50%35.7M shares | –Below 5% | Apr 2, 2025 | SEC |
Form 144: proposed insider sales
Notices from officers, directors and other affiliates planning to sell Opko Health, Inc. shares.
No Form 144 notices for Opko Health, Inc. are on file.